The Korean journal of helicobacter and upper gastrointestinal research最新文献_第6页

Endoscopic Removal of Multiple Toothbrushes: A Case Report. 内镜下多支牙刷拔除1例。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2025-03-01 Epub Date: 2025-03-07 DOI: 10.7704/kjhugr.2024.0060

Young Woo Chae, Ilsoo Kim, Woon Geon Shin

{"title":"Endoscopic Removal of Multiple Toothbrushes: A Case Report.","authors":"Young Woo Chae, Ilsoo Kim, Woon Geon Shin","doi":"10.7704/kjhugr.2024.0060","DOIUrl":"10.7704/kjhugr.2024.0060","url":null,"abstract":"Foreign body ingestion is a common emergency that necessitates endoscopic intervention. Although many foreign bodies are easily removed, removal of magnets, blades, barbs, and unusually shaped objects, such as toothbrushes is challenging. Toothbrush ingestion may potentially cause complications such as pressure ulcers and perforations. We present a rare case of a 26-year-old woman with schizophrenia, who ingested multiple foreign bodies but was asymptomatic. Radiography showed multiple toothbrushes in the stomach. Emergency non-sedated endoscopy revealed eight toothbrushes in the stomach; five toothbrushes lodged in the great curvature of the stomach and three in the duodenal bulb were successfully removed using a snare and a technique that involved neck hyperextension to facilitate passage. This report describes a case of non-sedated endoscopic removal of multiple toothbrushes, which is rarely reported in the literature. This case highlights that even complex foreign bodies can be safely removed via endoscopy without surgical intervention. To our knowledge, this is the first report in the English literature that discusses endoscopic removal of more than five toothbrushes and underscores the role of customized approaches in the management of ingestion of unusual foreign bodies.","PeriodicalId":520887,"journal":{"name":"The Korean journal of helicobacter and upper gastrointestinal research","volume":"25 1","pages":"70-72"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12173563/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Potential Unnecessity of Bismuth in Standard Triple Therapy for Clarithromycin-Susceptible Helicobacter pylori Infection. 在克拉霉素敏感幽门螺杆菌感染的标准三联治疗中，可能没有必要使用铋。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2025-03-01 Epub Date: 2025-03-07 DOI: 10.7704/kjhugr.2024.0077

Seon Woo Oh, Keun Sol Min, Hyung Geun Kim, Sunmi Lee, Chul-Hyun Lim, Jung-Hwan Oh

{"title":"Potential Unnecessity of Bismuth in Standard Triple Therapy for Clarithromycin-Susceptible Helicobacter pylori Infection.","authors":"Seon Woo Oh, Keun Sol Min, Hyung Geun Kim, Sunmi Lee, Chul-Hyun Lim, Jung-Hwan Oh","doi":"10.7704/kjhugr.2024.0077","DOIUrl":"10.7704/kjhugr.2024.0077","url":null,"abstract":"Objectives: The standard first-line treatment for Helicobacter pylori infection typically involves proton pump inhibitors, amoxicillin, and clarithromycin (PAC), yet the eradication success rates are not entirely satisfactory. Recognizing bismuth's antibacterial properties and its potential to enhance antibiotic efficacy, this study compared the eradication success rates of a 7-day course of PAC with bismuth (PACB) versus PAC alone in patients with clarithromycin-susceptible H. pylori infections.Methods: We conducted a retrospective review at Eunpyeong St. Mary's Hospital involving 499 patients with confirmed clarithromycin-susceptible H. pylori infection. These patients were treated either with PACB or PAC for 7 days. Clarithromycin resistance-associated point mutations were evaluated using reverse transcriptase polymerase chain reaction. Successful eradication was confirmed by a negative 13C-urea breath test.Results: Of the patients, 261 received PACB therapy, and 238 received PAC therapy. The intention-to-treat analysis showed eradication success rates of 82.8% (216/261) for PACB and 89.1% (212/238) for PAC (p=0.093). The per-protocol analysis revealed eradication rates of 85.3% (215/252) for PACB and 90.5% (210/232) for PAC (p=0.081). The incidence of adverse effects was similar between the two groups, with 41.3% (104/252) in the PACB group and 34.1% (79/232) in the PAC group (p=0.102).Conclusions: Adding bismuth to the standard 7-day PAC regimen did not significantly increase eradication rates in patients with clarithromycin-susceptible H. pylori infections compared to PAC alone.","PeriodicalId":520887,"journal":{"name":"The Korean journal of helicobacter and upper gastrointestinal research","volume":"25 1","pages":"48-53"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12173562/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gastric Ulcer Bleeding Caused by Systemic Inflammatory Response to Mycobacterial Bacteremia. 分枝杆菌菌血症引起的全身炎症反应引起胃溃疡出血。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2025-03-01 Epub Date: 2025-03-07 DOI: 10.7704/kjhugr.2024.0064e

Soo Bin Synn, Su Jin Kim

引用次数: 0

How Should Incidentally Detected Non-Ampullary Duodenal Neuroendocrine Tumors Be Treated? 偶然发现的非壶腹性十二指肠神经内分泌肿瘤应如何治疗？

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2025-03-01 Epub Date: 2025-03-07 DOI: 10.7704/kjhugr.2025.0015

Seung In Seo

引用次数: 0

Experts' Perceptions Regarding Testing for Helicobacter pylori Infection During Upper Gastrointestinal Endoscopy and Subsequent Eradication Therapy. 专家对上消化道内窥镜检查幽门螺杆菌感染及后续根除治疗的看法。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2025-03-01 Epub Date: 2025-03-07 DOI: 10.7704/kjhugr.2024.0073

Ilsoo Kim, Sang Pyo Lee, Jeong Wook Kim, Heung Up Kim, Tae Ho Kim, Seung Young Kim, Yu Jin Kim, Hee Seok Moon, Jung In Lee, Woon Geon Shin

{"title":"Experts' Perceptions Regarding Testing for Helicobacter pylori Infection During Upper Gastrointestinal Endoscopy and Subsequent Eradication Therapy.","authors":"Ilsoo Kim, Sang Pyo Lee, Jeong Wook Kim, Heung Up Kim, Tae Ho Kim, Seung Young Kim, Yu Jin Kim, Hee Seok Moon, Jung In Lee, Woon Geon Shin","doi":"10.7704/kjhugr.2024.0073","DOIUrl":"10.7704/kjhugr.2024.0073","url":null,"abstract":"Helicobacter pylori causes gastric cancer and peptic ulcers, and eradication therapy can reduce the incidence of cancer in high-risk groups. In Korea, discrepancies between the reimbursement criteria and clinical guidelines create clinical challenges. This study investigated the perceptions and practices of experts regarding H. pylori testing during upper gastrointestinal endoscopy and any subsequent eradication therapy. An anonymous 8-question survey was conducted among 51 experts attending the 2024 Korean College of Helicobacter and Upper Gastrointestinal Research Summer Workshop. Only 2% of the experts tested all patients. Testing was performed in 54% of patients with a family history of gastric cancer, 32% of those with atrophic gastritis, 42% of those with dyspeptic symptoms, and 62% of those with iron-deficiency anemia. Among patients with suspected infections (based on endoscopic findings) and eligible for selective reimbursement, 82% underwent H. pylori testing. Age did not influence testing decisions for 60% of the experts, and 57% considered factors other than age when deciding on eradication therapy. The practices of the experts varied depending on the patient's clinical condition and economic burden. Aligning clinical guidelines with the reimbursement criteria is necessary to reduce confusion and ensure appropriate patient care.","PeriodicalId":520887,"journal":{"name":"The Korean journal of helicobacter and upper gastrointestinal research","volume":"25 1","pages":"81-86"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12173579/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Step 1 Approach for Patients With Reflux Symptoms: Whom to Test and Whom to Treat? 1 .反流症状患者的治疗方法：该检测谁，该治疗谁？

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2025-03-01 Epub Date: 2025-03-07 DOI: 10.7704/kjhugr.2025.0016

Yu Kyung Cho

引用次数: 0

Gastric Subepithelial Lesion Accompanied by Colonic Subepithelial Mass. 胃上皮下病变伴结肠上皮下肿块。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2024-12-01 Epub Date: 2024-12-04 DOI: 10.7704/kjhugr.2024.0068

Hyun Lim, Hye-Young Sung, Dong Han Yeom, Yong Sung Kim

引用次数: 0

[The Relationship of Dysbiosis of Duodenal Microbiome and Functional Dyspepsia]. [十二指肠菌群失调与功能性消化不良的关系]。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2024-12-01 Epub Date: 2024-12-04 DOI: 10.7704/kjhugr.2024.0053

Nayoung Kim

{"title":"[The Relationship of Dysbiosis of Duodenal Microbiome and Functional Dyspepsia].","authors":"Nayoung Kim","doi":"10.7704/kjhugr.2024.0053","DOIUrl":"10.7704/kjhugr.2024.0053","url":null,"abstract":"Functional dyspepsia (FD) is a common gastrointestinal disorder characterized by chronic or recurrent epigastric pain or discomfort and postprandial fullness, without a definite organic cause. Despite the importance of FD in terms of decreased quality of life and recurrence, treatment modalities have been unsatisfactory, mainly because of their complex and heterogeneous nature. A link between microbiome dysbiosis and low-grade inflammation, along with mucosal barrier disruption of the duodenal mucosa, has been suggested and may be a potential target for FD treatment. This link supports the gut-brain (overactive visceral signaling and pain modulation) and the brain-gut (abnormal central processing) axes in FD. A definite increase in Streptococcus and a reduced abundance of Prevotella, Veillonella, and Actinomyces have also been observed. In addition, bacterial overgrowth is frequently observed in the small intestine, and rifaximin treatment improves the symptoms of FD, especially in women. This evidence highlights the importance of bacterial ecology in the development of FD symptoms. However, further research is necessary to prove the causal relationship between duodenal mucosal microbiota dysbiosis and FD.","PeriodicalId":520887,"journal":{"name":"The Korean journal of helicobacter and upper gastrointestinal research","volume":"24 4","pages":"327-338"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11967397/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144278199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Gastric Ulcer Bleeding Caused by Systemic Inflammatory Response to Mycobacterial Bacteremia]. [分枝杆菌菌血症引起全身炎症反应的胃溃疡出血]。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2024-12-01 Epub Date: 2024-12-04 DOI: 10.7704/kjhugr.2024.0064

Soo Bin Synn, Su Jin Kim

引用次数: 0

Pathological Evaluation of the Therapeutic Effects of Argon Plasma Coagulation in Gastric Low-Grade Dysplasia. 氩等离子凝血治疗胃低度发育不良的病理评价。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2024-12-01 Epub Date: 2024-12-04 DOI: 10.7704/kjhugr.2024.0048

Min Kyung Yeo, Sun Hyung Kang, Hyun Seok Lee, Hyuk Soo Eun, Hee Seok Moon, Eaum Seok Lee, Seok Hyun Kim, Jae Kyu Sung, Byung Seok Lee

{"title":"Pathological Evaluation of the Therapeutic Effects of Argon Plasma Coagulation in Gastric Low-Grade Dysplasia.","authors":"Min Kyung Yeo, Sun Hyung Kang, Hyun Seok Lee, Hyuk Soo Eun, Hee Seok Moon, Eaum Seok Lee, Seok Hyun Kim, Jae Kyu Sung, Byung Seok Lee","doi":"10.7704/kjhugr.2024.0048","DOIUrl":"10.7704/kjhugr.2024.0048","url":null,"abstract":"Objectives: Gastric dysplasia is primarily treated using endoscopic resection. Although argon plasma coagulation (APC) is an alternative treatment for older patients or those with bleeding tendencies, studies have reported a higher rate of local recurrence after APC than after endoscopic resection. Using pathological examinations, this study aimed to investigate the incidence and associated causative factors of residual dysplasia following APC.Methods: This prospective study recruited patients with low-grade gastric dysplasia from March 2020 to February 2021 and conducted follow-up examinations for 15 months after enrollment of the last patient. The patients were randomly assigned to undergo APC at an output power setting of 45, 60, or 80 W.Results: Residual lesions were found in 13 of 68 patients (19.1%) during the 24-h follow-up endoscopy and biopsy. The Ki-67 index, a marker of cellular proliferation, was significantly associated with the presence of residual lesions. The presence of residual dysplasia at the three-month follow-up was associated with the presence of residual lesions at the 24-h follow-up and a positive Ki-67 index. Only three of the 13 patients with residual lesions 24 h after APC demonstrated residual lesions at the three-month follow up. No post-procedural complications were observed.Conclusions: Residual dysplasia may persist even after APC and cause local recurrence. If Ki-67-positive cells are detected in the remnant tissue following APC, additional interventions should be considered.","PeriodicalId":520887,"journal":{"name":"The Korean journal of helicobacter and upper gastrointestinal research","volume":"24 4","pages":"353-359"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11967395/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144278151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0