The Korean journal of helicobacter and upper gastrointestinal research最新文献_第6页

Autoimmune Gastritis Associated With a Gastric Hyperplastic Polyp: Two Case Reports and Review of its Neoplastic Potential. 自身免疫性胃炎合并胃增生性息肉：两例报告及其肿瘤潜力的回顾

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2026-03-01 Epub Date: 2026-03-05 DOI: 10.7704/kjhugr.2025.0086

Myung-Hun Lee, Sung Eun Kim, Moo In Park, Kyoungwon Jung

{"title":"Autoimmune Gastritis Associated With a Gastric Hyperplastic Polyp: Two Case Reports and Review of its Neoplastic Potential.","authors":"Myung-Hun Lee, Sung Eun Kim, Moo In Park, Kyoungwon Jung","doi":"10.7704/kjhugr.2025.0086","DOIUrl":"10.7704/kjhugr.2025.0086","url":null,"abstract":"Autoimmune gastritis (AIG) results in the loss of oxyntic glands, achlorhydria, and hypergastrinemia and frequently leads to the development of gastric hyperplastic polyps (GHPs). AIG is increasingly being recognized as a major contributor to corpus-dominant atrophy in East Asia. Despite its increasing prevalence, it is frequently underdiagnosed in clinical practice. Although GHPs are typically benign, AIG is associated with an elevated risk of gastric cancer, including neuroendocrine tumors. Herein, we report two cases in which GHPs detected during screening endoscopy led to AIG identification. Both of the patients were negative for Helicobacter pylori and tested positive for antiparietal cell antibodies. Histological examination confirmed oxyntic atrophy and hyperplastic polyps, without any evidence of dysplasia. These case reports have highlighted that GHPs may develop in the context of H. pylori-associated gastritis as well as from autoimmune causes, thus emphasizing the importance of recognizing and assessing AIG during endoscopic screening. The possibility of coexisting AIG should be considered in individuals with GHPs. Accordingly, clinicians are advised to evaluate AIG when GHPs are detected in a background of corpus-dominant atrophy, as delayed recognition may miss the opportunity to identify a precancerous risk.","PeriodicalId":520887,"journal":{"name":"The Korean journal of helicobacter and upper gastrointestinal research","volume":"26 1","pages":"100-105"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12997057/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147477833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Management of Non-Variceal Upper Gastrointestinal Bleeding. 非静脉曲张性上消化道出血的处理。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2026-03-01 Epub Date: 2026-03-05 DOI: 10.7704/kjhugr.2025.0083

Hyunchul Lim

引用次数: 0

Endoscopic Management of Post-Sleeve Gastrectomy Leaks Using Long, Fully Covered Stents. 使用长、全覆盖支架治疗胃切除术后套管渗漏的内镜治疗。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2026-03-01 Epub Date: 2026-03-05 DOI: 10.7704/kjhugr.2025.0077

Chan Sunwoo, Jong Kyu Park, Tae Yeong Lee, Sang Jin Lee

引用次数: 0

Endoscopic Diagnosis of Remnant Gastric Cancer After Gastrectomy. 胃切除术后残余胃癌的内镜诊断。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2025-12-01 Epub Date: 2025-12-04 DOI: 10.7704/kjhugr.2025.0064

Ji Hyun Kim, Sung Chul Park

{"title":"Endoscopic Diagnosis of Remnant Gastric Cancer After Gastrectomy.","authors":"Ji Hyun Kim, Sung Chul Park","doi":"10.7704/kjhugr.2025.0064","DOIUrl":"10.7704/kjhugr.2025.0064","url":null,"abstract":"Remnant gastric cancer (RGC) can develop in patients who have undergone curative resection for gastric cancer and in those who have undergone gastrectomies for benign disorders such as peptic ulcer disease. Routine endoscopic surveillance is recommended for early detection of cancer at the anastomosis site or within the remnant stomach. However, endoscopy in postgastrectomy patients may be challenging because of the limited space of the remnant stomach, deformity at the anastomosis site, interference from retained food material, and inflammation associated with recurrent bile reflux. The interval and location of RGC occurrence may vary depending on the type of primary disease, the stage of the initial cancer, and the reconstruction method used. Elevated lesions are the most common finding in early stage RGC in the remnant stomach, whereas ulceroinfiltrative lesions are more frequently observed in advanced RGC at the anastomosis site. Therefore, meticulous examination of the gastric mucosa at both the anastomosis site and in the remnant stomach is crucial for the early detection and diagnosis of RGC in post-gastrectomy patients.","PeriodicalId":520887,"journal":{"name":"The Korean journal of helicobacter and upper gastrointestinal research","volume":"25 4","pages":"327-335"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12699064/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145746197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Superficial Esophageal Cancer Completely Cured With Radiotherapy Alone: A Case Report. 单纯放疗完全治愈浅表性食管癌1例。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2025-12-01 Epub Date: 2025-12-04 DOI: 10.7704/kjhugr.2025.0059

Hyung Jin Bae, Younghee Choe, Byung-Wook Kim

引用次数: 0

A 32-Year-Old Male Patient Presented With Symptoms of Indigestion. 32岁男性患者，表现为消化不良症状。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2025-12-01 Epub Date: 2025-12-04 DOI: 10.7704/kjhugr.2025.0046

Sun Hyung Kang

引用次数: 0

Assessment of the Prognostic Value of the ABC Score in Non-Variceal UGIB Showing Superiority to Traditional Scores, With Room for Improvement: A Retrospective Observational Study. 一项回顾性观察性研究：ABC评分在非静脉曲张UGIB中的预后价值优于传统评分，且有改进空间

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2025-12-01 Epub Date: 2025-12-04 DOI: 10.7704/kjhugr.2025.0053

Selen Kim, Sangyeong Lee, Ilsoo Kim, Jong-Uk Hou, Byung-Wook Kim

{"title":"Assessment of the Prognostic Value of the ABC Score in Non-Variceal UGIB Showing Superiority to Traditional Scores, With Room for Improvement: A Retrospective Observational Study.","authors":"Selen Kim, Sangyeong Lee, Ilsoo Kim, Jong-Uk Hou, Byung-Wook Kim","doi":"10.7704/kjhugr.2025.0053","DOIUrl":"10.7704/kjhugr.2025.0053","url":null,"abstract":"Objectives: Upper gastrointestinal bleeding (UGIB) is a critical medical emergency with a potentially fatal outcome. Early risk stratification is essential for determining the need for urgent interventions. Current guidelines recommend the use of risk-stratification models, among which the ABC score was recently developed. We aimed to validate the performance of the ABC score in comparison with the well-established Glasgow-Blatchford score (GBS), AIMS65, and pre-endoscopic Rockall score (PreRS).Methods: This retrospective single-center study included adult patients (≥18 years) who presented to the emergency department of Incheon St. Mary's Hospital with non-variceal UGIB between March 2019 and June 2022. The primary outcome was 30-day all-cause mortality. Secondary outcomes included a composite endpoint of hemostatic intervention (endoscopic, interventional radiologic, or surgical), hypotension (systolic blood pressure <90 mm Hg after 2 h), vasopressor use after 2 h, and rebleeding within 7 days. The predictive performance of the GBS, AIMS65, PreRS, and ABC scores was assessed using the area under the receiver operating characteristic curve (AUROC).Results: Of the 1597 enrolled patients, 116 (7.3%) died within 30 days. The ABC score demonstrated the highest performance (AUROC: 0.806; 95% confidence interval: 0.766-0.845) at predicting 30-day mortality, followed by the PreRS (0.734), GBS (0.679), and AIMS65 (0.558). The GBS had the highest AUROC (0.708), followed by the ABC (0.651), PreRS (0.626), and AIMS65 (0.529).Conclusions: The ABC score outperformed conventional risk models at predicting the 30-day mortality among patients with non-variceal UGIB. However, its predictive power for the need for intervention was inferior to that of the GBS.","PeriodicalId":520887,"journal":{"name":"The Korean journal of helicobacter and upper gastrointestinal research","volume":"25 4","pages":"355-362"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12699055/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145746648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Toxic Epidermal Necrolysis Induced by First-Line Helicobacter pylori Eradication Therapy: A Case Report. 一线幽门螺杆菌根除治疗致中毒性表皮坏死松解1例。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2025-12-01 Epub Date: 2025-12-04 DOI: 10.7704/kjhugr.2025.0051

Young Woo Chae, Seung In Seo, Woon Geon Shin

引用次数: 0

Follow-Up and Strategies After Curative Surgical Resection for Gastric Cancer. 胃癌根治性手术切除后的随访及治疗策略。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2025-12-01 Epub Date: 2025-12-04 DOI: 10.7704/kjhugr.2025.0056

Seokin Kang

{"title":"Follow-Up and Strategies After Curative Surgical Resection for Gastric Cancer.","authors":"Seokin Kang","doi":"10.7704/kjhugr.2025.0056","DOIUrl":"10.7704/kjhugr.2025.0056","url":null,"abstract":"With advances in gastric cancer treatment, survival outcomes following surgery have improved; however, recurrence remains a significant challenge. Postoperative follow-up is crucial for the early detection of recurrence, enabling timely intervention and improving long-term survival. In patients who undergo curative resection of gastric cancer, postoperative surveillance typically includes regular esophagogastroduodenoscopy, blood tests-including tumor marker assessments-and imaging studies such as computed tomography. However, there is limited evidence that such follow-up strategies contribute to improved long-term survival. Multiple international guidelines recommend postoperative follow-up schedules and strategies based on retrospective studies and expert opinions. The impact of Helicobacter pylori eradication on long-term outcomes after gastric cancer surgery remains a subject of ongoing debate. Secondary primary cancer following gastric cancer treatment is another issue during postoperative follow-up. Optimizing follow-ups using an individualized, evidence-based approach is crucial.","PeriodicalId":520887,"journal":{"name":"The Korean journal of helicobacter and upper gastrointestinal research","volume":"25 4","pages":"336-341"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12699063/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145746426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hemostatic Use of Over-the-Scope Clips in Non-Variceal Upper Gastrointestinal Bleeding: A Narrative Review. 在非静脉曲张上消化道出血中使用镜外夹止血：叙述性回顾。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2025-12-01 Epub Date: 2025-12-04 DOI: 10.7704/kjhugr.2025.0072

James Y W Lau

{"title":"Hemostatic Use of Over-the-Scope Clips in Non-Variceal Upper Gastrointestinal Bleeding: A Narrative Review.","authors":"James Y W Lau","doi":"10.7704/kjhugr.2025.0072","DOIUrl":"10.7704/kjhugr.2025.0072","url":null,"abstract":"The over-the-scope clip (OTSC) system is increasingly used for the endoscopic hemostasis of bleeding non-variceal upper gastrointestinal lesions. OTSCs provide secure, full-thickness tissue compression. The Stop the Bleeding Trial (STING-1) was a German multicenter randomized controlled trial (RCT) that compared OTSC to standard treatment (through-the-scope clips and contact thermal devices) for refractory bleeding ulcers. The rate of further bleeding was significantly reduced with the use of OTSC (19 of 33 patients [57.6%] in the standard therapy group and 5 of 33 patients [15.2%] in the OTSC group). As a first-line endoscopic treatment, OTSCs have been compared with standard treatments in five RCTs, including the STING-2 trial. OTSCs are generally superior in controlling bleeding. Therefore, we recommend the use of OTSCs for lesions with a high risk of further bleeding. These include large ulcers (2 cm in size or larger) located at the duodenal bulb and the lesser curve of the stomach, and ulcers with vessels >2 mm in size. We have also used OTSCs for Dieulafoy's lesions, often with thick submucosal arteries. An ongoing RCT is comparing the use of OTSCs with trans-arterial embolization (TAE) for refractory bleeding. TAE is considered the most definitive, but is associated with a 30% rate of further bleeding. The results of the RCT will help define the management algorithm for such cases.","PeriodicalId":520887,"journal":{"name":"The Korean journal of helicobacter and upper gastrointestinal research","volume":"25 4","pages":"342-349"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12699058/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145746472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0