The Korean journal of helicobacter and upper gastrointestinal research最新文献_第3页

A Survey on the Management and Surveillance of Low-Grade Gastric Adenoma Among Gastroenterologists in South Korea. 韩国胃肠病学家对低级别胃腺瘤的管理和监测调查。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2025-06-01 Epub Date: 2025-06-04 DOI: 10.7704/kjhugr.2025.0021

Jin Lee, Jae Yong Park, Joon Sung Kim, Young-Il Kim, Hyuk Lee, Su Youn Nam, Ki Taek Nam, Hyo-Joon Yang, Jong Yeul Lee

{"title":"A Survey on the Management and Surveillance of Low-Grade Gastric Adenoma Among Gastroenterologists in South Korea.","authors":"Jin Lee, Jae Yong Park, Joon Sung Kim, Young-Il Kim, Hyuk Lee, Su Youn Nam, Ki Taek Nam, Hyo-Joon Yang, Jong Yeul Lee","doi":"10.7704/kjhugr.2025.0021","DOIUrl":"10.7704/kjhugr.2025.0021","url":null,"abstract":"Objectives: Low-grade gastric adenomas (LGA) are managed using a variety of methods, unlike high-grade adenomas or early gastric cancers, which follow more standardized treatment protocols. This study aimed to assess the current practices and follow-up strategies used by South Korean gastroenterologists in managing LGA.Methods: An online survey was created with Google Forms and distributed to South Korean gastroenterologists via email or paper instructions containing a Quick Response code.Results: A total of 130 South Korean gastroenterologists responded to the survey. The size criteria for endoscopic treatment of LGAs were as follows: size-independent (68.5%), ≥5 mm (13.1%), ≥1 cm (16.2%), ≥1.5 cm (0.8%), and ≥2 cm (1.5%). Treatment decisions, such as performing endoscopic submucosal dissection, were primarily influenced by lesion size (88.5%), endoscopic appearance (62.3%), and location (41.5%). For lesions ≥1.5 cm, 85.3% (n=111) of respondents favored endoscopic submucosal dissection, whereas for lesions ≤1 cm, endoscopic mucosal resection or argon plasma coagulation was preferred. Regarding follow-up endoscopy intervals, most respondents (70.0%) conducted follow-up within 6 months post-endoscopic resection, with subsequent endoscopies at 1-year intervals.Conclusions: This study provides a detailed overview of the current management strategies for LGAs among South Korean gastroenterologists, highlighting the variability in approaches. Further research is required to develop more standardized guidelines for the management and surveillance of LGA.","PeriodicalId":520887,"journal":{"name":"The Korean journal of helicobacter and upper gastrointestinal research","volume":"25 2","pages":"152-158"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12173576/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bridging the Gap in Management of Gastric Subepithelial Lesions: Time for Standardized Care. 弥合胃上皮下病变管理的差距：标准化护理的时间。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2025-06-01 Epub Date: 2025-06-04 DOI: 10.7704/kjhugr.2025.0031

Jong Yeul Lee

引用次数: 0

Gastric Adenocarcinoma and Synchronic Mantle Cell Lymphoma: A Case Report. 胃腺癌合并同期套细胞淋巴瘤1例。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2025-06-01 Epub Date: 2025-06-04 DOI: 10.7704/kjhugr.2025.0017

Carina Toledo Scoparo Barioni, Isabelli Zeitz de Castro, Julio Cezar Uili Coelho, Samya Hamad Mehanna, Eduardo Morais de Castro

{"title":"Gastric Adenocarcinoma and Synchronic Mantle Cell Lymphoma: A Case Report.","authors":"Carina Toledo Scoparo Barioni, Isabelli Zeitz de Castro, Julio Cezar Uili Coelho, Samya Hamad Mehanna, Eduardo Morais de Castro","doi":"10.7704/kjhugr.2025.0017","DOIUrl":"10.7704/kjhugr.2025.0017","url":null,"abstract":"The synchronous coexistence of primary neoplasms with diverse histogeneses in the gastrointestinal tract is rare, particularly the association between gastric adenocarcinoma and mantle cell lymphoma (MCL). Gastric adenocarcinoma is a common neoplasm, often associated with risk factors such as Helicobacter pylori infection and poor eating habits. Notably, MCL is an uncommon and aggressive type of non-Hodgkin's lymphoma, accounting for approximately 5% of lymphoma diagnoses. This report describes the case of a 74-year-old former smoker diagnosed with gastric adenocarcinoma and MCL of the perigastric lymph nodes. Adenocarcinoma was detected by evaluating the gastrointestinal symptoms, followed by upper gastrointestinal endoscopy and biopsy. MCL was diagnosed after evaluation of the lymph nodes obtained from the surgical specimen and confirmed using immunohistochemistry. This report highlights the importance of a detailed diagnostic approach for cases of synchronous neoplasms and the need for integrated therapeutic management considering the different biological characteristics of each type of neoplasm.","PeriodicalId":520887,"journal":{"name":"The Korean journal of helicobacter and upper gastrointestinal research","volume":"25 2","pages":"167-171"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12173588/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Series of Inadvertent Misplacements of Nasogastric Tube in a Patient. 一例病人鼻胃管误放的病例分析。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2025-06-01 Epub Date: 2025-06-04 DOI: 10.7704/kjhugr.2025.0002

Heung Up Kim

引用次数: 0

Autoimmune Gastritis: Unveiling the Mystery. 自身免疫性胃炎：揭开谜底

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2025-06-01 Epub Date: 2025-04-21 DOI: 10.7704/kjhugr.2025.0011

Yong Hwan Ahn, Yong Sung Kim

{"title":"Autoimmune Gastritis: Unveiling the Mystery.","authors":"Yong Hwan Ahn, Yong Sung Kim","doi":"10.7704/kjhugr.2025.0011","DOIUrl":"10.7704/kjhugr.2025.0011","url":null,"abstract":"Atrophic gastritis is primarily caused by Helicobacter pylori infection and autoimmune mechanisms. In South Korea, where H. pylori infections remain highly prevalent, standardized guidelines for the use of serological testing or biopsies for diagnosing autoimmune gastritis (AIG) have not been developed. Recently, as H. pylori infection rates have declined and trends associated with gastric cancer and gastric neuroendocrine neoplasms (gNENs) have shifted, interest in AIG has increased, particularly in Asia. However, AIG diagnoses are often delayed owing to a lack of suspicion; even when AIG is considered, the limited understanding of the disease hampers its accurate diagnosis. Furthermore, the absence of established treatments and standardized follow-up protocols pose significant challenges for patient management. The loss of gastric acid secretion, a critical component of digestive function, and destruction of the gastric corpus mucosa are caused by autoimmune mechanisms, leading to incomplete protein digestion, micronutrient deficiencies, gut microbiota imbalances, and elevated gastrin levels that eventually contribute to neoplastic lesions, such as gNENs and gastric cancer. Although AIG is an immunerelated gastrointestinal disorder, it intersects with various disciplines, including pathology, genetics, microbiology, endocrinology, hematology, and oncology, and many unresolved issues remain in these areas. Research to address unanswered questions about the disease pathogenesis, the relationship between AIG and H. pylori, appropriate diagnostic methods and the risk of gastric neoplasms has previously been published. This review provides an overview of the current findings and explores unanswered questions surrounding AIG to help elucidate its complex pathogenesis, clinical implications, and potential management strategies.","PeriodicalId":520887,"journal":{"name":"The Korean journal of helicobacter and upper gastrointestinal research","volume":"25 2","pages":"134-145"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12173590/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of Helicobacter pylori Screening on Gastric Cancer Incidence and Mortality. 幽门螺杆菌筛查对胃癌发病率和死亡率的影响。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2025-06-01 Epub Date: 2025-06-04 DOI: 10.7704/kjhugr.2025.0003

Hyun Ho Choi

引用次数: 0

Treatment of Refractory Gastric Outlet Obstruction After Endoscopic Submucosal Dissection With Endoscopic Antralplasty and Stent Placement: A Case Report. 内镜下粘膜下剥离术后胃出口梗阻的内镜胃窦成形术及支架置入术治疗1例。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2025-06-01 Epub Date: 2025-06-04 DOI: 10.7704/kjhugr.2025.0019

Sunghoon Kim, Kwang Bum Cho, Ju Yup Lee

{"title":"Treatment of Refractory Gastric Outlet Obstruction After Endoscopic Submucosal Dissection With Endoscopic Antralplasty and Stent Placement: A Case Report.","authors":"Sunghoon Kim, Kwang Bum Cho, Ju Yup Lee","doi":"10.7704/kjhugr.2025.0019","DOIUrl":"10.7704/kjhugr.2025.0019","url":null,"abstract":"Endoscopic submucosal dissection (ESD) has emerged as a standard minimally invasive treatment for early gastric cancer and precancerous lesions. However, extensive resection near the pyloric ring or antrum can lead to post-ESD gastric outlet obstruction (GOO) due to cicatricial stenosis and luminal deformation. This report presents a case of a 79-year-old man who developed severe GOO following ESD for an antral tubular adenoma with low-grade dysplasia. Initial management with endoscopic antralplasty and local triamcinolone injection failed to provide sustained symptomatic relief. As a salvage therapy, a partially covered self-expandable metallic stent (SEMS) was placed across the antrum, pyloric ring, and proximal duodenum. This intervention resulted in complete resolutions of obstructive symptoms and restoration of normal oral intake. The SEMS was successfully removed after 4 weeks with no recurrence of GOO symptoms thereafter. This case highlights the therapeutic challenges of post-ESD GOO and demonstrates that SEMS placement is a viable salvage treatment for refractory cases. Further studies are required to optimize treatment strategies and assess long-term outcomes.","PeriodicalId":520887,"journal":{"name":"The Korean journal of helicobacter and upper gastrointestinal research","volume":"25 2","pages":"178-183"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12173567/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Barrett's Esophagus. 巴雷特食管。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2025-06-01 Epub Date: 2025-06-04 DOI: 10.7704/kjhugr.2022.0015e

Yong Kang Lee

引用次数: 0

Esophageal Mucosal Injuries From Drugs, Radiation, and Caustic Agents. 药物、辐射和腐蚀剂对食管黏膜的损伤。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2025-06-01 Epub Date: 2025-06-04 DOI: 10.7704/kjhugr.2025.0023

Hyung Jin Bae, Younghee Choe

{"title":"Esophageal Mucosal Injuries From Drugs, Radiation, and Caustic Agents.","authors":"Hyung Jin Bae, Younghee Choe","doi":"10.7704/kjhugr.2025.0023","DOIUrl":"10.7704/kjhugr.2025.0023","url":null,"abstract":"Various factors can lead to esophageal mucosal injury. A thorough patient history is crucial to accurately diagnose esophageal injuries caused by drugs, radiation, and caustic agents. These conditions are often identifiable based on characteristic clinical features, concomitant diseases, and endoscopic findings and do not necessarily require histological confirmation through biopsies. Regardless of the underlying cause, avoiding or minimizing the offending agent is essential for preventing further mucosal damage. In cases where this is unavoidable, such as radiationinduced esophageal injuries, careful adjustment of the radiation dose, field, and frequency is necessary. Additionally, the use of mucosal protective agents and adherence to a soft diet can help regenerate the mucosal epithelium. Esophageal mucosal injuries can cause chronic complications, such as esophageal strictures; therefore, they require close monitoring. Notably, injuries induced by caustic agents carry an increased risk of progression to esophageal cancer, underscoring the importance of long-term surveillance.","PeriodicalId":520887,"journal":{"name":"The Korean journal of helicobacter and upper gastrointestinal research","volume":"25 2","pages":"126-133"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12173573/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Eosinophilic Esophagitis: Emerging Insights Into Diagnosis and Management. 嗜酸性粒细胞性食管炎：诊断和治疗的新见解。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2025-06-01 Epub Date: 2025-06-04 DOI: 10.7704/kjhugr.2025.0013

Hyun Ho Choi

{"title":"Eosinophilic Esophagitis: Emerging Insights Into Diagnosis and Management.","authors":"Hyun Ho Choi","doi":"10.7704/kjhugr.2025.0013","DOIUrl":"10.7704/kjhugr.2025.0013","url":null,"abstract":"Eosinophilic esophagitis (EoE) is a chronic, immune-mediated, esophageal disease characterized by eosinophilic infiltration and symptoms such as dysphagia, food impaction, and esophageal dysfunction. Advances in diagnostic tools, including the EoE Endoscopic Reference Score and the Eosinophilic Esophagitis Histologic Scoring System, have improved disease characterization and monitoring. First-line treatments, such as proton pump inhibitors and topical corticosteroids, achieve significant histological and clinical remission rates. Dietary approaches, including the six-food elimination diet and step-up strategies, provide effective non-pharmacological options, although adherence remains a challenge. Esophageal dilation is a safe and effective therapy for relieving symptoms of dysphagia caused by strictures. Emerging biological therapies, such as dupilumab, show promise for targeting specific inflammatory pathways and addressing refractory cases. Although current therapies have demonstrated efficacy, gaps remain in the optimization of long-term disease control and treatment sequencing.","PeriodicalId":520887,"journal":{"name":"The Korean journal of helicobacter and upper gastrointestinal research","volume":"25 2","pages":"117-125"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12173586/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0