The Korean journal of helicobacter and upper gastrointestinal research最新文献_第2页

Autoimmune Gastritis: An Evolving Entity. 自身免疫性胃炎：一个不断发展的实体。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2026-09-01 Epub Date: 2026-09-08 DOI: 10.7704/kjhugr.2026.0047

Chan-Muk Im

引用次数: 0

Occurrence of New Helicobacter pylori Infections in Healthy, Helicobacter pylori-Negative Adults: A Prospective Observational Study. 健康幽门螺杆菌阴性成人新发幽门螺杆菌感染的发生：一项前瞻性观察研究

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2026-09-01 Epub Date: 2026-09-08 DOI: 10.7704/kjhugr.2026.0004

Young-Il Kim, Myeong-Cherl Kook, Jong Yeul Lee, Chan Gyoo Kim, Il Ju Choi

{"title":"Occurrence of New Helicobacter pylori Infections in Healthy, Helicobacter pylori-Negative Adults: A Prospective Observational Study.","authors":"Young-Il Kim, Myeong-Cherl Kook, Jong Yeul Lee, Chan Gyoo Kim, Il Ju Choi","doi":"10.7704/kjhugr.2026.0004","DOIUrl":"10.7704/kjhugr.2026.0004","url":null,"abstract":"Objectives: The annual incidence of new Helicobacter pylori infections evaluated by serological test in Korean adults has been reported to be 2.1%-3.3%. This study evaluated the rate of new H. pylori infections using the urea breath test (UBT) and the factors associated with new infection.Methods: In this prospective observational study, we recruited participants from the National Cancer Screening Program who tested negative for H. pylori infection by both rapid urease test and histology between November 2007 and December 2014. The participants underwent the UBT to check their follow-up H. pylori infection status from August 2015 to December 2017. The primary outcome of this study was new H. pylori infection.Results: A total of 192 participants were enrolled in this study. During the mean follow-up of 4.1 years from the initial negative tests for H. pylori infection, a new infection occurred in six participants (3.1%, 6/192 participants). According to analyses using the logistic regression model, age (odds ratio [OR], 1.13; 95% confidence interval [CI], 1.02-1.26) and corpus atrophy (OR, 9.83; 95% CI, 1.59-60.98) were associated with the new H. pylori infection in univariate analyses. However, no significant factors were identified in multivariate analysis.Conclusions: New H. pylori infection rarely occurred in Korean adults, with a rate of 3.1%. However, no independent risk factors for new infection were identified.","PeriodicalId":520887,"journal":{"name":"The Korean journal of helicobacter and upper gastrointestinal research","volume":"26 3","pages":"300-306"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13586464/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148993599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rapidly Progressive Gastric Poorly Differentiated Neuroendocrine Carcinoma Mimicking Gastrointestinal Stromal Tumor: A Case Report. 模拟胃肠道间质瘤的快速进展性胃低分化神经内分泌癌1例报告。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2026-09-01 Epub Date: 2026-09-08 DOI: 10.7704/kjhugr.2026.0038

Yonghoon Choi

{"title":"Rapidly Progressive Gastric Poorly Differentiated Neuroendocrine Carcinoma Mimicking Gastrointestinal Stromal Tumor: A Case Report.","authors":"Yonghoon Choi","doi":"10.7704/kjhugr.2026.0038","DOIUrl":"10.7704/kjhugr.2026.0038","url":null,"abstract":"Poorly differentiated gastric neuroendocrine carcinoma (NEC) represents a rare but highly aggressive malignancy, typically diagnosed at advanced stages, which are associated with poor prognosis. We present a case of a 71-year-old male with a history of distal gastrectomy who developed recurrent gastrointestinal bleeding from a subepithelial gastric mass. The lesion initially measured approximately 2 cm and demonstrated endoscopic and radiological features reminiscent of gastrointestinal stromal tumors (GIST). Repeated endoscopic biopsies indicated weak c-KIT and DOG1 positivity; however, the mass enlarged rapidly to 8 cm within 2 months, accompanied by multiple hepatic metastases. Ultrasound-guided liver biopsy confirmed the diagnosis of poorly differentiated gastric NEC. Cisplatin-based palliative chemotherapy was initiated, but the patient died within 3 weeks due to persistent hemorrhage and rapid clinical decline. Although uncommon, gastric NEC may closely mimic GIST both clinically and pathologically. Accurate differentiation between these entities is essential, given their markedly divergent prognoses and therapeutic approaches.","PeriodicalId":520887,"journal":{"name":"The Korean journal of helicobacter and upper gastrointestinal research","volume":"26 3","pages":"324-329"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13586454/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148993595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Intraductal Papillary Mucinous Neoplasm-Like Lesion Manifesting as a Duodenal Polyp: A Rare Case Report. 表现为十二指肠息肉的导管内乳头状黏液性肿瘤样病变：罕见病例报告。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2026-09-01 Epub Date: 2026-09-08 DOI: 10.7704/kjhugr.2026.0030

Suna Yu, Min Joo Yoon, Eui Sun Jeong, Euno Choi, Hye-Kyung Jung, Seong-Eun Kim, Seryun Bae

{"title":"An Intraductal Papillary Mucinous Neoplasm-Like Lesion Manifesting as a Duodenal Polyp: A Rare Case Report.","authors":"Suna Yu, Min Joo Yoon, Eui Sun Jeong, Euno Choi, Hye-Kyung Jung, Seong-Eun Kim, Seryun Bae","doi":"10.7704/kjhugr.2026.0030","DOIUrl":"10.7704/kjhugr.2026.0030","url":null,"abstract":"Intraductal papillary mucinous neoplasms (IPMNs) typically originate within the pancreatic ductal system. However, the occurrence of an IPMN-like mucinous neoplasm outside the pancreas, presenting as an isolated duodenal polyp, is extremely rare. An asymptomatic 64-year-old woman underwent routine screening endoscopy, which revealed a 25-mm Yamada type IV pedunculated polypoid lesion in the second portion of the duodenum. En bloc endoscopic mucosal resection was performed without procedural complications, although histological evaluation revealed focal involvement of the deep resection margin. Histopathological examination demonstrated a mucinous neoplasm confined within the duodenal submucosa with papillary architecture and low-grade dysplasia, which was designated as a duodenal IPMN-like lesion. Post-procedural CT showed no concurrent pancreatic involvement, and endoscopy at 6 months demonstrated a stable post-resection scar without local recurrence. Extended follow-up with dedicated pancreatic imaging is ongoing. This case report describes a particularly uncommon duodenal IPMN-like lesion presenting as a polyp. This case highlights the importance of careful histological evaluation and the inclusion of pancreaticobiliary-type neoplasms in the differential diagnosis of atypical periampullary lesions, along with long-term surveillance.","PeriodicalId":520887,"journal":{"name":"The Korean journal of helicobacter and upper gastrointestinal research","volume":"26 3","pages":"345-350"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13586463/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148993548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Undetected Gastric Angiodysplastic Lesion Causing Obscure Gastrointestinal Bleeding. 未被发现的胃血管发育不良病变引起隐晦的胃肠道出血。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2026-09-01 Epub Date: 2026-09-08 DOI: 10.7704/kjhugr.2026.0011

Donghyoun Lee, Heung Up Kim, Hyun Joo Song

{"title":"Undetected Gastric Angiodysplastic Lesion Causing Obscure Gastrointestinal Bleeding.","authors":"Donghyoun Lee, Heung Up Kim, Hyun Joo Song","doi":"10.7704/kjhugr.2026.0011","DOIUrl":"10.7704/kjhugr.2026.0011","url":null,"abstract":"Obscure gastrointestinal bleeding (OGIB) has traditionally been defined to as bleeding originating from the small intestine that is beyond the reach of esophagogastroduodenoscopy and colonoscopy. However, gastric lesions associated with chronic intermittent bleeding may be undetected if there is no overt bleeding during initial endoscopic examination, resulting in a diagnosis of OGIB and repeated complex follow-up investigations. Vascular lesions, including angiodysplasia, Dieulafoy's lesion, and small vascular ectasias, are major causes of chronic intermittent gastrointestinal bleeding. Hematemesis is an important clue for identifying the upper gastrointestinal tract as the source of anemia. Even when these vascular lesions are small and undetected, or not recognized as foci of bleeding during the initial endoscopy, confirmation of interval changes in size and morphology on follow-up endoscopy may provide an opportunity for definitive treatment of the lesion. Herein, we report a case of a patient with chronic anemia accompanied by recurrent syncope in whom no bleeding focus was identified on the initial endoscopic examination. After the patient had overt hematemesis, upper gastrointestinal bleeding was strongly suspected. Follow-up end oscopy revealed an angiodysplastic lesion with interval changes in size and morphology, which was recognized as the source of bleeding, and it was successfully treated endoscopically.","PeriodicalId":520887,"journal":{"name":"The Korean journal of helicobacter and upper gastrointestinal research","volume":"26 3","pages":"340-344"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13586465/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148993563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

EtCO2 Instability as an Early Warning During Endoscopic Submucosal Dissection Sedation. 内镜下粘膜剥离镇静过程中EtCO2不稳定的早期预警。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2026-06-01 Epub Date: 2026-06-08 DOI: 10.7704/kjhugr.2026.0033

Donghoon Kang

引用次数: 0

A Case of Localized Gastric Amyloidosis With Improvement on Endoscopy After Eradication of Helicobacter pylori. 幽门螺杆菌根除后内镜改善的局限性胃淀粉样变性1例。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2026-06-01 Epub Date: 2026-06-08 DOI: 10.7704/kjhugr.2025.0092

Na Rae Lim, Dongkyung Shin, Woo Chul Chung

{"title":"A Case of Localized Gastric Amyloidosis With Improvement on Endoscopy After Eradication of Helicobacter pylori.","authors":"Na Rae Lim, Dongkyung Shin, Woo Chul Chung","doi":"10.7704/kjhugr.2025.0092","DOIUrl":"10.7704/kjhugr.2025.0092","url":null,"abstract":"Amyloidosis is a disease characterized by the abnormal accumulation of amyloids in tissues. The kidneys and heart are the most commonly affected organs in systemic amyloidosis. Primary localized gastric amyloidosis (LGA), on the other hand, is relatively rare. Some past studies have suggested a potential link between Helicobacter pylori infection and LGA, but more research is needed in order to support this hypothesis. A 37-year-old female patient complained of nausea and underwent an endoscopic examination. A 3.0-cm depressed mucosal lesion and mucosal fragility were observed in the upper and posterior gastric wall. She was referred to our hospital with ulcerative bleeding. The silver and Congo red staining results were positive. Echocardiography and abdominal computed tomography were performed to rule out systemic amyloid, and no evidence of systemic involvement was observed. Eradication therapy with standard triple therapy was administered, and successful eradication was confirmed. Two years after the successful eradication, an endoscopic follow-up examination revealed mucosal retraction; however, the mucosal inflammation, including edema and mucosal softening, significantly improved.","PeriodicalId":520887,"journal":{"name":"The Korean journal of helicobacter and upper gastrointestinal research","volume":"26 2","pages":"235-238"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13284570/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148280693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rifasutenizol-Based Triple Therapy for the Eradication of Helicobacter pylori. 利法替唑三联疗法根除幽门螺杆菌。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2026-06-01 Epub Date: 2026-06-08 DOI: 10.7704/kjhugr.2026.0006

Yeon Ji Kim

引用次数: 0

Endoscopic Evaluation of a Gastric Mass Mimicking a Subepithelial Tumor. 模拟上皮下肿瘤的胃肿块的内镜评估。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2026-06-01 Epub Date: 2026-06-08 DOI: 10.7704/kjhugr.2026.0022

Younghee Choe, Byung-Wook Kim

引用次数: 0

A Case of Oxyntic Gland Neoplasm Incidentally Found During Upper Endoscopic Screening. 上腔镜检查中偶然发现的氧合腺肿瘤1例。

The Korean journal of helicobacter and upper gastrointestinal research Pub Date : 2026-06-01 Epub Date: 2026-06-08 DOI: 10.7704/kjhugr.2025.0078

Ji Yoon Kim, Joo Hyun Lim

{"title":"A Case of Oxyntic Gland Neoplasm Incidentally Found During Upper Endoscopic Screening.","authors":"Ji Yoon Kim, Joo Hyun Lim","doi":"10.7704/kjhugr.2025.0078","DOIUrl":"10.7704/kjhugr.2025.0078","url":null,"abstract":"Oxyntic gland neoplasms (OGNs) are rare gastric epithelial tumors characterized by primary differentiation into chief cells and, to a lesser extent, parietal cells. It includes oxyntic gland adenoma and gastric adenocarcinoma of the fundic gland type (GA-FG) depending on the depth of invasion. Although generally indolent, another subgroup, GA-FG mucosa type, may exhibit more invasive behavior. We report a case of an asymptomatic 57-year-old man in whom a small, slightly elevated hyperemic lesion was incidentally found on surveillance endoscopy. Endoscopic mucosal resection using the cap-assisted method (EMR-C) was performed following a biopsy, which suggested a fundic gland-type neoplasm. Histopathologic evaluation confirmed GA-FG with submucosal invasion, but no lymphovascular invasion (pT1b). Post-EMR CT and follow-up endoscopy revealed no evidence of recurrence or metastasis. Recognition of OGNs require histopathologic and immunohistochemical confirmation using markers such as MUC-5AC and MUC-6. In most cases, complete endoscopic resection is curative. Further studies with larger cohorts and long-term follow-ups are needed in order to clarify the natural course and optimal management of this rare neoplasm.","PeriodicalId":520887,"journal":{"name":"The Korean journal of helicobacter and upper gastrointestinal research","volume":"26 2","pages":"239-244"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13284571/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148280667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0