Cellular and molecular biology (Noisy-le-Grand, France)最新文献

{"title":"Re-positive PCR of SARS-CoV-2 in health care persons during COVID-19 pandemic.","authors":"Masoud Alebouyeh,&nbsp;Pooya Aavani,&nbsp;Nareen Arif Abdulrahman,&nbsp;Azad Abduljabar Haleem,&nbsp;Abdollah Karimi,&nbsp;Shahnaz Armin,&nbsp;Fatemeh Fallah,&nbsp;Arezu Amirali,&nbsp;Saeed Sadr,&nbsp;Ghazaleh Ghandchi,&nbsp;Nafiseh Abdollahi,&nbsp;Roxana Mansour Ghanaie,&nbsp;Sedigheh Rafiei Tabatabaei,&nbsp;Seyed Alireza Fahimzad,&nbsp;Raheleh Razmara,&nbsp;Khalid J Alzahrani,&nbsp;Ghamartaj Khanbabaee,&nbsp;Soheila Sadat Vaghefi,&nbsp;Farid Imanzadeh,&nbsp;Peyman Eshghi,&nbsp;Leila Azimi","doi":"10.14715/cmb/2021.67.5.19","DOIUrl":"https://doi.org/10.14715/cmb/2021.67.5.19","url":null,"abstract":"<p><p>Reinfection rate with SARS-CoV-2 and degree of protection by the induced antibody after the first episode of the infection is not well known, so it makes a big dilemma for health care personnel (HCP) who work in the front line of combating SARS-CoV-2. In this study, we investigated the frequency of SARS-CoV-2 redetection among HCP after the initial onset of the infection in a children's hospital during one year. Out of 131 seropositive HCP, 13.7% of them were symptomatic and PCR positive during 74-360 days after first sampling. Analysis of demographic data of seropositive HCP showed a correlation between a higher number of family members, higher body mass index, and the existence of underlying diseases with SARS-CoV-2 redetection. In conclusion, reinfection is one of the important problems in the SARS-CoV-2 pandemic. Research on this topic can help us to find answers to questions for estimating the duration of human protection with produced immunity after the infection or vaccination.</p>","PeriodicalId":520584,"journal":{"name":"Cellular and molecular biology (Noisy-le-Grand, France)","volume":" ","pages":"138-143"},"PeriodicalIF":1.6,"publicationDate":"2022-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40513164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Propofol Regulates the Expression of BecliN-1 through miR-30b and Protects against Lung Ischemia-Reperfusion Injury.","authors":"Huanju Kang,&nbsp;Junjie Chen,&nbsp;Su Cao","doi":"10.14715/cmb/2021.67.5.47","DOIUrl":"https://doi.org/10.14715/cmb/2021.67.5.47","url":null,"abstract":"<p><p>Pulmonary ischemia-reperfusion can cause severe dysfunction of alveolar epithelium and alveolar cells. Drugs such as propofol have a protective effect on lung ischemia-reperfusion, but this protective mechanism is not stable and requires other factors such as nucleosides. The purpose of this article is to study the protective mechanism of propofol on lung ischemia-reperfusion injury by regulating the expression of BecliN-1 by miR-30b. With 72 male rats as the research object, a rat lung ischemia-reperfusion model was established. Phenol agents were perfused as the perfusion solution to detect the expression levels of miR-30b and BecliN-1, statistical experimental data and analyze the regulatory mechanism of miR-30b on the expression of BecliN-1 and the effect of propofol on the protection of lung ischemia-reperfusion. Research results show that propofol can reduce inflammation, reduce oxidative stress, inhibit lung tissue apoptosis, improve lung function and pathological changes of lung tissue by inhibiting the activation of the JAK-STAT signaling pathway, and propofol can pass. The protection of miR-30b's regulation of BecliN-1 expression against lung ischemia-reperfusion injury is 30% higher than that of other protective mechanisms. At the same time, the apoptosis rate of inflammatory lung tissue cells is reduced by 13%.</p>","PeriodicalId":520584,"journal":{"name":"Cellular and molecular biology (Noisy-le-Grand, France)","volume":" ","pages":"348-355"},"PeriodicalIF":1.6,"publicationDate":"2022-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40607874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expression of LncRNA-BCYRN1 in pediatric asthma and related factors of disease induction.","authors":"Xufeng Huang,&nbsp;Zhengguo Huang,&nbsp;Chengliang Shao,&nbsp;Bin Zheng,&nbsp;Jing Zhang","doi":"10.14715/cmb/2021.67.5.34","DOIUrl":"https://doi.org/10.14715/cmb/2021.67.5.34","url":null,"abstract":"<p><p>The study aimed to investigate the expression of lncRNA-BCYRN1 in serum of pediatric asthma patients and the related factors of disease induction. For this purpose, a total of 95 patients were randomly selected from the outpatient department of pediatrics of a hospital affiliated with the medical university from October 2018 to October 2019, including 25 intermittent episodes, 25 mild persistent episodes, 20 moderate persistent episodes, and 20 severe persistent episodes. In addition, serum samples from 30 healthy control children were selected for comparison. The expression levels of lncRNA-BCYRN1 and the inflammatory factors IL-4, IL-12, IL-37, 25-(OH)D in serum were detected by real-time quantitative fluorescence PCR(qrt-PCR), and the influence of the expression of lncRNA-BCYRN1 on the prognosis of children and its correlation with the expression of TNF-a and IgE were analyzed. Results: the expression of LncRNA BCYRN1 was positively correlated with the expression of TNF-α and IgE (r=0.712, 0.748, all P<0.001). Serum IL-4 levels in each group were 21.06±2.93pg/ml, 23.88±3.91pg/ ml, 25.85±4.02pg/ml, and 17.74±1.77pg/ml, respectively. Serum IL-4 levels in each group were higher than those in the normal control group, and the difference was statistically significant (P<0.001). The levels of IL-12, IL-37 and 25-(OH)D in all the affected groups were decreased compared with the normal control group, while the serum levels of IL-37 were negatively correlated with IL-4 and positively correlated with IL-12 and 25-(OH)D. Conclusion: serum IL-4 level of children in the disease group was increased, indicating hyperexpression of Th2 cell function, and serum IL-12 and IL-37 levels were decreased, suggesting decreased Th1 cell function, indicating Th1/Th2 imbalance in children with asthma. The low serum vitamin D level of children in the disease group was negatively correlated with serum IL-4 level and positively correlated with IL-12 and IL-37 levels, which may be the trigger factor of inflammation in asthmatic diseases and should be supplemented in clinical treatment. The expression level of lncRNA-BCYRN1 is related to the severity of pediatric asthma, which can be used as a prognostic indicator and has a certain effect on the prognosis of clinical pediatric asthma.</p>","PeriodicalId":520584,"journal":{"name":"Cellular and molecular biology (Noisy-le-Grand, France)","volume":" ","pages":"248-255"},"PeriodicalIF":1.6,"publicationDate":"2022-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40494315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identifying the alpha-glucosidase inhibitory potential of dietary phytochemicals against diabetes mellitus type 2 via molecular interactions and dynamics simulation.","authors":"Mohd Adnan Kausar,&nbsp;Sma Shahid,&nbsp;Sadaf Anwar,&nbsp;M Kuddus,&nbsp;Mohammad Kalim Ahmad Khan,&nbsp;Amany Mohammed Khalifa,&nbsp;Fahmida Khatoon,&nbsp;Abdullah D Alotaibi,&nbsp;Salman F Alkhodairy,&nbsp;Mejdi Snoussi,&nbsp;Jamal M Arif","doi":"10.14715/cmb/2021.67.5.3","DOIUrl":"https://doi.org/10.14715/cmb/2021.67.5.3","url":null,"abstract":"<p><p>The research aims to identify the inhibitory potential of natural dietary phytochemicals against non-insulinotropic target protein alpha-glucosidase and its possible implications to diabetes mellitus type 2. A data set of sixteen plant-derived dietary molecules viz., 4,5-dimethyl-3-hydroxy-2(5H)-furanone, apigenin, bromelain, caffeic acid, cholecalciferol, dihydrokaempferol 7-o-glucopyranoside, galactomannan, genkwanin, isoimperatorin, luteolin, luteolin 7-o-glucoside, neohesperidin, oleanoic acid, pelargonidin-3-rutinoside, quercetin, and quinic acid were taken to accomplish molecular docking succeeded by their comparison with known inhibitors including acarbose, miglitol, voglibose, emiglitate, and 1-deoxynojirimycin. Among all phyto-compounds, bromelain (ΔG: -9.54 kcal/mol), cholecalciferol (-8.47 kcal/mol), luteolin (-9.02 kcal/mol), and neohesperidin (-8.53 kcal/mol) demonstrated better binding interactions with alpha-glucosidase in comparison to the best-known inhibitor, acarbose (ΔG: -7.93 kcal/mol). Molecular dynamics simulation of 10 ns duration, CYP450 site of metabolism identification, and prediction of activity spectra for substances depicted the bromelain as the most stable inhibitor compared to luteolin and acarbose. Findings of molecular interactions, molecular dynamics study, metabolism, and biological activity prediction proved bromelain as a potential alpha-glucosidase inhibitor. Thus, bromelain might be helpful as an insulin-independent therapeutic molecule towards controlling and managing diabetes mellitus type 2.</p>","PeriodicalId":520584,"journal":{"name":"Cellular and molecular biology (Noisy-le-Grand, France)","volume":" ","pages":"16-26"},"PeriodicalIF":1.6,"publicationDate":"2022-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40582312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potassium Ion Channel Protein (KCNH) Levels in Patients with Fibromyalgia Syndrome.","authors":"Ayca Tas,&nbsp;Emrullah Hayta,&nbsp;Ahmet Karadag,&nbsp;Cemile Zontul,&nbsp;Esma Ozmen,&nbsp;Süleyman Aydin,&nbsp;Yavuz Silig","doi":"10.14715/cmb/2021.67.5.57","DOIUrl":"https://doi.org/10.14715/cmb/2021.67.5.57","url":null,"abstract":"<p><p>Although there is not yet full clarity of the pathogenesis of fibromyalgia syndrome (FM), central sensitization is considered to be responsible. The purpose of this study was to measure the plasma levels of potassium ion channel proteins (human KCNH2, KCNH6 and KCNH7) in FM patients and healthy control subjects. The study sample includes 76 newly diagnosed FM patients and 79 healthy individuals. Venous blood samples were taken to measure the plasma levels of KCNH2, KCNH6 and KCNH7. Pain severity in FM patients was assessed using a visual analog scale (VAS). Bioinformatics analysis was performed using the STRING v 11 Protein interaction tool. Age, gender and body mass index were seen to be similar in both groups. In comparisons between FM and control groups, KCNH2 plasma levels was found to be significantly lower in the FM group. No significant correlation was found between plasma levels of KCNH2, KCNH6 and KCNH7 protein levels and VAS score of patients with FM. The KCNH2 protein had a high homology score with 9 proteins. The plasma levels of KCNH2 FM patients were found to be lower than those of the healthy control subjects, no difference was determined in respect of the plasma levels of KCNH6 and KCNH7. These results may be of use in guiding future studies on the pathogenesis of FM.</p>","PeriodicalId":520584,"journal":{"name":"Cellular and molecular biology (Noisy-le-Grand, France)","volume":" ","pages":"451-457"},"PeriodicalIF":1.6,"publicationDate":"2022-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40584332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diclofenac biotransformation and toxicity assessment of laccase from Pleurotus floridanus.","authors":"Dhrisya Chenthamara,&nbsp;Sankar Ganesh Ramakrishnan,&nbsp;Ameer Khusro,&nbsp;Sadhasivam Subramaniam,&nbsp;Saad Alghamdi,&nbsp;Mazen Almehmadi,&nbsp;Ahmed Kabrah,&nbsp;Muhammad Umar Khayam Sahibzada,&nbsp;Aziz Eftekhari","doi":"10.14715/cmb/2021.67.5.56","DOIUrl":"https://doi.org/10.14715/cmb/2021.67.5.56","url":null,"abstract":"<p><p>Laccase producing fungus Pleurotus floridanus was isolated from Siruvani forest, Tamil Nadu, India. The potential of P. floridanus to produce laccase by using various lignocellulosic substrates was screened under submerged fermentation. Laccase production in the presence of lignocellulosic substrates such as rice, wheat and maize bran as a sole source of carbon as well as an additional supplement was examined. Laccase activity of P. floridanus using varied substrates was observed in the order of rice bran > wheat bran > maize bran. The isolate showed maximum laccase activity of 13.29±0.01 U/mL using rice bran as a carbon source within 11 days. This was 18 fold higher than the control media that lacks lignocellulosic substrates. The diclofenac tolerance was assessed in solid media at various concentrations and the results showed that the mycelia growth is not significantly affected by the drug. Finally, the laccase mediated degradation of diclofenac at a concentration of 10 mg/L showed 98% degradation in 2 h. The phytotoxicity of the crude laccase treated diclofenac was lower than the untreated diclofenac. In conclusion, findings suggested direct application of crude laccase produced from P. floridanus using agro-residues as ideal substrate for environmental applications.</p>","PeriodicalId":520584,"journal":{"name":"Cellular and molecular biology (Noisy-le-Grand, France)","volume":" ","pages":"439-450"},"PeriodicalIF":1.6,"publicationDate":"2022-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40584333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Her-2/Neu Gene Amplification or Expression between IHC and FISH in BC.","authors":"Qinqin Zhang,&nbsp;Lei Jin,&nbsp;Hua Gong","doi":"10.14715/cmb/2021.67.5.52","DOIUrl":"https://doi.org/10.14715/cmb/2021.67.5.52","url":null,"abstract":"<p><p>This study aimed to analyze and compare the application of FISH and IHC in BC tissue Her-2 / neu gene amplification or expression. For this purpose, 110 patients with BC were selected. FISH and IHC were performed on the BC tissues that were surgically removed, and the results were compared and analyzed. The results showed that in 110 BC tissues, the expression of HER-2 protein was (+++) 25 cases (22.73%); (++) 44 cases (40%); (+) 26 cases (23.64%); (1) 15 cases (13.64%). There were 42 cases of HER-2 gene amplification in 110 BC tissues, and 68 cases had no amplification. IHC test positive (+++) is consistent with FISH positive coincidence rate, IHC test negative (+/-) is consistent with FISH negative coincidence rate, IHC test suspicious positive (++) compared with the FISH result, the difference is statistically significant. However, the total coincidence rate between IHC test results and FISH test results was 89.29 (25/28), and the two test methods were positively correlated. Generally, IHC positive and negative expressions are in good agreement with FISH test results. The suspected positive expression of IHC is inconsistent with the FISH test result, suggesting that the IHC test is suspicious, and the positive specimens need to be tested by FISH.</p>","PeriodicalId":520584,"journal":{"name":"Cellular and molecular biology (Noisy-le-Grand, France)","volume":" ","pages":"399-404"},"PeriodicalIF":1.6,"publicationDate":"2022-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40607869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Possible Mechanism of Placental Mesenchymal Stem Cell-Derived Neural Cell Transplantation on the Recovery of Neurogenic Bladder Function after Spinal Cord Injury.","authors":"Ming Yao,&nbsp;Guo Liu,&nbsp;Yourui Li,&nbsp;Hualei Song","doi":"10.14715/cmb/2021.67.5.46","DOIUrl":"https://doi.org/10.14715/cmb/2021.67.5.46","url":null,"abstract":"<p><p>After spinal cord injury, more neurogenic bladder function is caused. The purpose of this article is to investigate the possible mechanism of placental mesenchymal stem cell-derived neural cell transplantation on the recovery of neurogenic bladder function after spinal cord injury. 50 SPF Wistar rats were selected to establish a spinal cord injury rat model and divided into experimental groups and in the control group, 25 animals in each group, the experimental group was transplanted with placental mesenchymal stem cell-derived nerve cells, and the urodynamics and TUNEL positive rate were compared. The results of the study showed that compared with the control group, the maximum bladder capacity and bladder compliance of the experimental group increased significantly (P<0.01), and the bladder basic pressure and urinary leakage pressure decreased (P<0.05). The values of these four items are 2.318ml, 28.892cm H2O, 46.34cm H2O, and 0.1389ml/cm H2O, respectively. It can be seen that the transplantation of neural cells derived from placental mesenchymal stem cells is of great significance for the recovery of neurogenic bladder function after spinal cord injury.</p>","PeriodicalId":520584,"journal":{"name":"Cellular and molecular biology (Noisy-le-Grand, France)","volume":" ","pages":"340-347"},"PeriodicalIF":1.6,"publicationDate":"2022-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40607875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MiR-143-3p Increases the Radiosensitivity of Breast Cancer Cells Through FGF1.","authors":"Dewen Wang,&nbsp;Chunying Wang,&nbsp;Lei Sun,&nbsp;Xiang Lu,&nbsp;Jiangwei Shi,&nbsp;Jing Chen,&nbsp;Xuesong Zhang","doi":"10.14715/cmb/2021.67.5.35","DOIUrl":"https://doi.org/10.14715/cmb/2021.67.5.35","url":null,"abstract":"<p><p>Breast cancer is a common malignant tumor in women. At present, the main treatment for breast cancer is radiotherapy. Due to the difference in radiosensitivity between individuals or tumor cells, the effect of radiotherapy is not good. Therefore, in radiotherapy, how to use various auxiliary means to reduce the radiation resistance of tumor, Therefore, it has become an important research topic to improve the radiosensitivity of the tumor. Fibroblast growth factor-1 (FGF1) plays an important role in tumor migration. Therefore, the study of miR-143-3p increasing the radiosensitivity of breast cancer cells through FGF1 is proposed in this paper. In this study, a control group experiment was set up to study. During the experiment, the relative expression of miR-143-3p was detected by fluorescent quantitative PCR of miRNA, and the cell irradiation experiment was created to analyze the radiosensitivity of breast cancer cells by comparing their survival fraction. The results of this study showed that when the radiation dose was 0, the survival scores of the three groups were all 1. The survival fraction of the experimental group decreased from 0.26 ± 0.045 to 0.068 ± 0.008 when the dose was added to 4Gy. The survival fraction of the experimental group was always greater than that of the two control groups. The results of this study show that miR-143-3p can increase the radiosensitivity of breast cancer cells through FGF1.</p>","PeriodicalId":520584,"journal":{"name":"Cellular and molecular biology (Noisy-le-Grand, France)","volume":" ","pages":"256-262"},"PeriodicalIF":1.6,"publicationDate":"2022-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40494314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Remifentanil Anesthesia on the Expression of Apoptosis-Related Proteins Bcl-2 and Bax in Rat Myocardial Cells with Ischemia-Reperfusion Injury.","authors":"Jie Li,&nbsp;Shuguang Wang,&nbsp;Shaoyan Huang,&nbsp;Wei Shao,&nbsp;Jianzhong Zhang","doi":"10.14715/cmb/2021.67.5.13","DOIUrl":"https://doi.org/10.14715/cmb/2021.67.5.13","url":null,"abstract":"<p><p>Ischemia-reperfusion damage to the myocardium is inevitable. This study mainly explored the effect of remifentanil anesthesia on the expression of apoptosis-related proteins Bcl-2 and Bax in rat myocardial ischemia-reperfusion injury. Select 48 mice (n=6). First, prepare solutions of different concentrations of remifentanil. A model of ischemia-reperfusion cardiomyocytes was established, and 6 slices of tissue were taken from each specimen, and the positive cells were observed with an optical microscope and magnified 100 times. Bcl-2 and Bax were positive in the cytoplasm and yellowish-brown particles in the inner membrane. According to the distribution of positive cells, randomly select 3 clear fields of view from each part, count the number of positive cells in each field, and then take the average of the proportion of positive cells to get Bcl-2 or Bax protein-positive Index (PEI). Comparison of mRNA levels in each group: Compared with the R3 group, the ratio of the M, R1, and R2 groups increased, and the mRNA expression level of the M group increased almost 3 times, P<0.05. The results of the study show that remifentanil reduces the mortality of myocardial cells by regulating the appearance of Bcl-2 and Bax proteins, and has a certain protective effect on the rat heart during myocardial ischemia and reperfusion. There is no statistically significant difference in the protective effect of remifentanil on myocardial ischemia-reperfusion.</p>","PeriodicalId":520584,"journal":{"name":"Cellular and molecular biology (Noisy-le-Grand, France)","volume":" ","pages":"96-103"},"PeriodicalIF":1.6,"publicationDate":"2022-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40513170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}