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Medical Mycology Case Reports最新文献

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A case of intracranial infection caused by Aspergillus flavus originating from chronic otitis media 一例由慢性中耳炎黄曲霉菌引起的颅内感染病例
IF 2.2
Medical Mycology Case Reports Pub Date : 2024-02-28 DOI: 10.1016/j.mmcr.2024.100637
Ling Yang , Jiacun Su , Chao Zhuo
{"title":"A case of intracranial infection caused by Aspergillus flavus originating from chronic otitis media","authors":"Ling Yang ,&nbsp;Jiacun Su ,&nbsp;Chao Zhuo","doi":"10.1016/j.mmcr.2024.100637","DOIUrl":"https://doi.org/10.1016/j.mmcr.2024.100637","url":null,"abstract":"<div><p>Central nervous system (CNS) aspergillosis is uncommon in immunocompetent patients. We present a 64-year-old man with chronic otitis media and uncontrolled diabetes. <em>Aspergillus flavus</em> was identified in cerebrospinal fluid via metagenomics next-generation sequencing technology. Initial voriconazole treatment offered limited relief, but personalized dosage adjustments, guided by drug concentration, led to remission. This case underscores the importance of diverse diagnostic approaches and tailored therapy for CNS <em>Aspergillus</em> infections.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"44 ","pages":"Article 100637"},"PeriodicalIF":2.2,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000113/pdfft?md5=a0e4659cb433cb495b53e4ba554c76d1&pid=1-s2.0-S2211753924000113-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140308701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Necrotizing pancreatitis with invasive candidiasis and candidemia due to Candida albicans and pan-echinocandin-resistant Candida glabrata 坏死性胰腺炎伴有白念珠菌和泛耐药念珠菌引起的侵袭性念珠菌病和念珠菌血症
IF 2.2
Medical Mycology Case Reports Pub Date : 2024-02-20 DOI: 10.1016/j.mmcr.2024.100636
Laman Rahimli , Jon Salmanton-García , Philipp Kasper , Michaela Simon , Oliver A. Cornely , Jannik Stemler
{"title":"Necrotizing pancreatitis with invasive candidiasis and candidemia due to Candida albicans and pan-echinocandin-resistant Candida glabrata","authors":"Laman Rahimli ,&nbsp;Jon Salmanton-García ,&nbsp;Philipp Kasper ,&nbsp;Michaela Simon ,&nbsp;Oliver A. Cornely ,&nbsp;Jannik Stemler","doi":"10.1016/j.mmcr.2024.100636","DOIUrl":"https://doi.org/10.1016/j.mmcr.2024.100636","url":null,"abstract":"<div><p>We report on a 64-year-old man with necrotizing pancreatitis related, invasive candidiasis, and candidemia. Despite a multidisciplinary management including antifungal therapy, endoscopic interventions and surgery, the patients’ infection progressed and lead to colon perforation, retroperitoneal abscess formation, and polymicrobial bloodstream infections. Resistance to echinocandins in <em>Candida glabrata</em> further complicated the course. This report emphasizes the need for vigilant monitoring and exploring alternative therapeutic approaches for patients in critical conditions.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"43 ","pages":"Article 100636"},"PeriodicalIF":2.2,"publicationDate":"2024-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000101/pdfft?md5=39373b7d47b4cf3bb8d8df2754e50021&pid=1-s2.0-S2211753924000101-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139936748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Haemophagocytic lymphohistiocytosis secondary to disseminated histoplasmosis in an immunocompetent patient 免疫功能正常患者继发于播散性组织胞浆菌病的嗜血细胞淋巴组织细胞增多症
IF 2.2
Medical Mycology Case Reports Pub Date : 2024-02-18 DOI: 10.1016/j.mmcr.2024.100635
Mallory Morton , Vinay Vanguru , Joo-Shik Shin , Amrita Ronnachit
{"title":"Haemophagocytic lymphohistiocytosis secondary to disseminated histoplasmosis in an immunocompetent patient","authors":"Mallory Morton ,&nbsp;Vinay Vanguru ,&nbsp;Joo-Shik Shin ,&nbsp;Amrita Ronnachit","doi":"10.1016/j.mmcr.2024.100635","DOIUrl":"https://doi.org/10.1016/j.mmcr.2024.100635","url":null,"abstract":"<div><p>Haemophagocytic lymphohistiocytosis secondary to <em>Histoplasma</em> infection is rare and almost always occurs in immunocompromised hosts. We report a 32-year-old immunocompetent man presenting with a nonspecific febrile illness found to have disseminated histoplasmosis and associated haemophagocytic lymphohistiocytosis. The diagnosis was confirmed on histopathological examination and PCR of liver and bone marrow biopsies. He was successfully treated with steroids, intravenous immunoglobulin and itraconazole.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"43 ","pages":"Article 100635"},"PeriodicalIF":2.2,"publicationDate":"2024-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000095/pdfft?md5=fa483becfeccbcdb38767fa88aada861&pid=1-s2.0-S2211753924000095-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139941679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Septic arthritis caused by Candida dubliniensis following arthroscopic surgery 关节镜手术后由杜布林念珠菌引起的化脓性关节炎
IF 2.2
Medical Mycology Case Reports Pub Date : 2024-02-16 DOI: 10.1016/j.mmcr.2024.100634
Nayla Azanki Hatem , Alessandro C. Pasqualotto , Cecília Bittencourt Severo , Rafael Hannaui Bastos , Rafael de Luca de Lucena , Cezar Vinícius Würdig Riche
{"title":"Septic arthritis caused by Candida dubliniensis following arthroscopic surgery","authors":"Nayla Azanki Hatem ,&nbsp;Alessandro C. Pasqualotto ,&nbsp;Cecília Bittencourt Severo ,&nbsp;Rafael Hannaui Bastos ,&nbsp;Rafael de Luca de Lucena ,&nbsp;Cezar Vinícius Würdig Riche","doi":"10.1016/j.mmcr.2024.100634","DOIUrl":"https://doi.org/10.1016/j.mmcr.2024.100634","url":null,"abstract":"<div><p>A 37-year-old immunocompetent man was admitted to the emergency department due to recurrent pain and oedema of his right knee. Two months earlier, he had undergone surgery to repair his meniscus. Arthroscopic joint lavage was performed and <em>Candida dubliniensis</em> was recovered in culture. The authors describe the first case of septic arthritis caused by <em>Candida dubliniensis</em>.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"43 ","pages":"Article 100634"},"PeriodicalIF":2.2,"publicationDate":"2024-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000083/pdfft?md5=d88caddd8014e8308e78e612f3e1a892&pid=1-s2.0-S2211753924000083-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139908468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genotyping and clonal origin of Sporothrix brasiliensis in human sporotrichosis cases in Argentina 阿根廷人类孢子丝虫病病例中巴西孢子丝虫的基因分型和克隆起源
IF 2.2
Medical Mycology Case Reports Pub Date : 2024-02-16 DOI: 10.1016/j.mmcr.2024.100633
Norma B. Fernandez , Bram Spruijtenburg , Iris N. Tiraboschi , Jacques F. Meis , Ana Lugo , María Cecilia López Joffre , Eelco F.J. Meijer
{"title":"Genotyping and clonal origin of Sporothrix brasiliensis in human sporotrichosis cases in Argentina","authors":"Norma B. Fernandez ,&nbsp;Bram Spruijtenburg ,&nbsp;Iris N. Tiraboschi ,&nbsp;Jacques F. Meis ,&nbsp;Ana Lugo ,&nbsp;María Cecilia López Joffre ,&nbsp;Eelco F.J. Meijer","doi":"10.1016/j.mmcr.2024.100633","DOIUrl":"https://doi.org/10.1016/j.mmcr.2024.100633","url":null,"abstract":"<div><p><em>Sporothrix brasiliensis</em> is considered a highly virulent emerging pathogen that causes sporotrichosis in humans, mainly after zoonotic transmission from infected cats. The epidemic of this zoonosis that originated from Brazil has spread in the last decades, generating hyperendemic regions in Latin America. We present two cases of human sporotrichosis causes by <em>S. brasiliensis</em> in Buenos Aires, Argentina, with good clinical response to differing treatments after contact with sick cats. Using Short tandem repeat (STR) genotyping, the two <em>S. brasiliensis</em> cases appear to be introduced from Brazil and likely originate from the same source.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"43 ","pages":"Article 100633"},"PeriodicalIF":2.2,"publicationDate":"2024-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000071/pdfft?md5=9b9dc75c7eb7ee8becadf652f81e04a6&pid=1-s2.0-S2211753924000071-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139936749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tinea capitis due to Microsporum ferrugineum: A case of unusual laboratory finding on direct microscopic examination of infected hairs and skin lesions 铁锈色小孢子菌引起的头癣：对受感染的毛发和皮损进行直接显微镜检查时发现的一例异常实验室病例
IF 2.2
Medical Mycology Case Reports Pub Date : 2024-02-01 DOI: 10.1016/j.mmcr.2024.100629
Robab Ebrahimibarogh , Mona Ghazanfari , Tahereh Shokohi , Ensieh Yousefiabdolmaleki , Amir Seyedmousavi , Mohammad T. Hedayati
{"title":"Tinea capitis due to Microsporum ferrugineum: A case of unusual laboratory finding on direct microscopic examination of infected hairs and skin lesions","authors":"Robab Ebrahimibarogh ,&nbsp;Mona Ghazanfari ,&nbsp;Tahereh Shokohi ,&nbsp;Ensieh Yousefiabdolmaleki ,&nbsp;Amir Seyedmousavi ,&nbsp;Mohammad T. Hedayati","doi":"10.1016/j.mmcr.2024.100629","DOIUrl":"https://doi.org/10.1016/j.mmcr.2024.100629","url":null,"abstract":"<div><p>Tinea capitis is a chronic fungal infection of the scalp occurring commonly in children of school age, especially in developing countries. It is caused primarily by the dermatophyte members of genera <em>Microsporum</em> and <em>Trichophyton</em>. Here we report presence of free-living mycelial stage of dermatophytes, a stage of fungal growth which form in culture medias, around affected hairs and skin scrapings of scalp lesions in a 3-year-old boy presenting with alopecia and multiple scaly, non-erythematous plaques. On direct microscopy examination using 10 % potassium hydroxide, the fungal hyphae and arthrospores were detected in ectothrix form. In addition, we also observed numerous multicellular, thick-walled spindle-shaped macroconidia around hairs and skin scrapings. To our knowledge this is the first study reporting dermatophyte's macroconidia directly seen on clinical samples. Species level identification of the dermatophyte isolate growing on Mycosel™ agar was confirmed by PCR-sequencing of internal transcribed spacer of ribosomal RNA as <em>Microsporum ferrugineum.</em> The patient was successfully treated with systemic itraconazole combined with topical ketoconazole shampoo.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"43 ","pages":"Article 100629"},"PeriodicalIF":2.2,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000034/pdfft?md5=80b983de33d7ba9ce034beac2ea401c5&pid=1-s2.0-S2211753924000034-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139718572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Malassezia infection associated with stucco keratosis 与灰泥角化病相关的马拉色菌感染
IF 2.2
Medical Mycology Case Reports Pub Date : 2024-01-28 DOI: 10.1016/j.mmcr.2024.100630
Zhan Zhou , Jiali Zhu , Bin Jiao , Songgan Jia , Yanping Jiang
{"title":"Malassezia infection associated with stucco keratosis","authors":"Zhan Zhou ,&nbsp;Jiali Zhu ,&nbsp;Bin Jiao ,&nbsp;Songgan Jia ,&nbsp;Yanping Jiang","doi":"10.1016/j.mmcr.2024.100630","DOIUrl":"https://doi.org/10.1016/j.mmcr.2024.100630","url":null,"abstract":"<div><p>We report a case of a 20-year-old young woman with a large stucco keratosis in the mons veneris, one of the clinical variants of Seborrheic keratoses (SKs). Periodic acid-Schiff staining revealed a large number of <em>Malassezia</em> spores in the stratum corneum. After oral antifungal treatment with itraconazole for 4 weeks, the benign tumor was completely cleared without residue or recurrence, which may open a new perspective for exploring the pathogenesis of SKs.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"43 ","pages":"Article 100630"},"PeriodicalIF":2.2,"publicationDate":"2024-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000046/pdfft?md5=ffa78a443013fa62817ec77b44b48e3c&pid=1-s2.0-S2211753924000046-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139654187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oral mucosa sporotrichosis: Report of a rare case acquired by direct inoculation 口腔粘膜孢子丝菌病：报告一例通过直接接种获得的罕见病例
IF 2.2
Medical Mycology Case Reports Pub Date : 2024-01-24 DOI: 10.1016/j.mmcr.2024.100631
Syed Nabil , Mohd Ferdaus Isa , Badrul Iskandar Abdul Wahab , Nurismah Md Isa
{"title":"Oral mucosa sporotrichosis: Report of a rare case acquired by direct inoculation","authors":"Syed Nabil ,&nbsp;Mohd Ferdaus Isa ,&nbsp;Badrul Iskandar Abdul Wahab ,&nbsp;Nurismah Md Isa","doi":"10.1016/j.mmcr.2024.100631","DOIUrl":"10.1016/j.mmcr.2024.100631","url":null,"abstract":"<div><p>Sporotrichosis is a rare type of fungal infection caused by <em>Sporothrix</em> fungus. Transmissions are commonly by traumatic inoculation of the fungus through the skin and subcutaneous tissue either from environmental exposure or contact with infected animals. Due to its mode of transmission, it is commonly affecting the upper limbs. Definitive diagnosis can be obtained by fungal culture test on secretion fluids, pus, bloods or tissue biopsy. We report a rare presentation of this disease appearing as a solitary chronic ulcer of the lip which was successfully treated with itraconazole.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"43 ","pages":"Article 100631"},"PeriodicalIF":2.2,"publicationDate":"2024-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000058/pdfft?md5=a97630fd0f2cf32e22f56e4fa393555c&pid=1-s2.0-S2211753924000058-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139638982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Palatal mucormycosis in a 2-month-old child: A very rare case report and a literature review 2个月大婴儿的腭粘液瘤病：非常罕见的病例报告和文献综述
IF 2.2
Medical Mycology Case Reports Pub Date : 2024-01-22 DOI: 10.1016/j.mmcr.2024.100628
Yasser Al-Ghabra , Mohammad Hamdi , Ahmad Alkheder , Ahmad Kammasha , Shams Shamso , Adham Bader Aldeen Mohsen
{"title":"Palatal mucormycosis in a 2-month-old child: A very rare case report and a literature review","authors":"Yasser Al-Ghabra ,&nbsp;Mohammad Hamdi ,&nbsp;Ahmad Alkheder ,&nbsp;Ahmad Kammasha ,&nbsp;Shams Shamso ,&nbsp;Adham Bader Aldeen Mohsen","doi":"10.1016/j.mmcr.2024.100628","DOIUrl":"10.1016/j.mmcr.2024.100628","url":null,"abstract":"<div><p>A 2-month-old Syrian male child presented with a large blackish ulcerating lesion on his hard palate, along with fever, diarrhea, vomiting, and milk regurgitation from the nose. The child was diagnosed with palatal mucormycosis by histopathology and underwent treatment with liposomal amphotericin B and surgical debridement. However, despite treatment, the child's condition deteriorated, and he died from respiratory failure. An underlying immunodeficiency was not diagnosed, but the family history revealed several deaths of the child's siblings at very early ages due to poorly documented complicated metabolic syndromes. An autopsy was refused by the parents due to cultural reasons.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"43 ","pages":"Article 100628"},"PeriodicalIF":2.2,"publicationDate":"2024-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000022/pdfft?md5=4df4570033271019c97490a871754653&pid=1-s2.0-S2211753924000022-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139638681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endobronchial amphotericin B to treat hemoptysis in an inoperable patient with aspergillosis 用支气管内两性霉素 B 治疗一名无法手术的曲霉菌病患者的咯血症状
IF 2.2
Medical Mycology Case Reports Pub Date : 2024-01-14 DOI: 10.1016/j.mmcr.2024.100627
Mário Pinto, João Rodrigues, Marta Silva, Dionísio Maia, António Miguel
{"title":"Endobronchial amphotericin B to treat hemoptysis in an inoperable patient with aspergillosis","authors":"Mário Pinto,&nbsp;João Rodrigues,&nbsp;Marta Silva,&nbsp;Dionísio Maia,&nbsp;António Miguel","doi":"10.1016/j.mmcr.2024.100627","DOIUrl":"https://doi.org/10.1016/j.mmcr.2024.100627","url":null,"abstract":"<div><p>A 37-year-old man presented with chronic cavitary pulmonary aspergillosis and hemoptysis refractory to systemic antifungal therapy with voriconazole and bronchial artery embolization. Surgical excision was unfeasible due to the patient's refusal of blood transfusions. Ten sessions of intracavitary instillation of amphotericin B via flexible bronchoscopy were then performed. Hemoptysis cessation and aspergilloma resolution were achieved, with no toxicity or side effects, and the clinical benefits were sustained at six months of follow-up.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"43 ","pages":"Article 100627"},"PeriodicalIF":2.2,"publicationDate":"2024-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000010/pdfft?md5=4ff2508192a1e1e69000e7dccd698270&pid=1-s2.0-S2211753924000010-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139493414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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