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Meningeal sporotrichosis in an immunocompetent host: A case report 免疫功能正常宿主的脑膜孢子丝菌病：病例报告
IF 1.6
Medical Mycology Case Reports Pub Date : 2024-09-01 DOI: 10.1016/j.mmcr.2024.100665
Victor Teatini Ribeiro , Rachel Basques Caligiorne , Aldrin Pedroza Martins , Antônio Pereira Gomes Neto , Paulo Pereira Christo
{"title":"Meningeal sporotrichosis in an immunocompetent host: A case report","authors":"Victor Teatini Ribeiro ,&nbsp;Rachel Basques Caligiorne ,&nbsp;Aldrin Pedroza Martins ,&nbsp;Antônio Pereira Gomes Neto ,&nbsp;Paulo Pereira Christo","doi":"10.1016/j.mmcr.2024.100665","DOIUrl":"10.1016/j.mmcr.2024.100665","url":null,"abstract":"<div><p>A 78-year-old woman presented to hospital with altered mental status. Hyponatremia was diagnosed and treated. She maintained mental confusion despite normal sodium. No headache, fever or focal signs were present. CSF analysis showed chronic meningitis; MRI demonstrated basilar enhancement. She was empirically treated for tuberculosis, with no improvement. PCR for <em>Sporothrix</em> in the CSF was positive. After treatment with Amphotericin followed by oral itraconazole, she completely recovered her cognitive abilities. Follow-up CSF was normal. This report illustrates the need to consider sporotrichosis in the differential diagnosis of chronic meningitis in immunocompetent, and the importance of PCR as a diagnostic tool.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"45 ","pages":"Article 100665"},"PeriodicalIF":1.6,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000393/pdfft?md5=87f779cac484c1888ea96b8fe682203e&pid=1-s2.0-S2211753924000393-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142149331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Primary treatment of chronic pulmonary aspergillosis with weekly liposomal amphotericin B: A case report from Uganda 每周使用两性霉素 B 脂质体初治慢性肺曲霉菌病：乌干达的病例报告
IF 1.6
Medical Mycology Case Reports Pub Date : 2024-08-27 DOI: 10.1016/j.mmcr.2024.100666
Winnie Kibone , Felix Bongomin , David W. Denning , David B. Meya
{"title":"Primary treatment of chronic pulmonary aspergillosis with weekly liposomal amphotericin B: A case report from Uganda","authors":"Winnie Kibone ,&nbsp;Felix Bongomin ,&nbsp;David W. Denning ,&nbsp;David B. Meya","doi":"10.1016/j.mmcr.2024.100666","DOIUrl":"10.1016/j.mmcr.2024.100666","url":null,"abstract":"<div><p>Chronic pulmonary aspergillosis (CPA) treatment in Africa remains unexplored. We present a 23-year-old Ugandan male, previously treated thrice for pulmonary tuberculosis, developing CPA. Imaging showed lung fibrosis, bronchiectasis, and a fungal ball. He received weekly 600mg (10mg/kg) of liposomal amphotericin B for six weeks, leading to marked clinical improvement. Weekly liposomal amphotericin B may be a viable treatment option for CPA in resource-limited settings.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"46 ","pages":"Article 100666"},"PeriodicalIF":1.6,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S221175392400040X/pdfft?md5=869eeb1f4620398c42e0bdd62fda606c&pid=1-s2.0-S221175392400040X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142229852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cutaneous Purpureocillium lilacinum and Fusarium coinfection in a heart transplant recipient 一名心脏移植受者的皮肤紫癜疫霉菌和镰刀菌并发感染
IF 1.6
Medical Mycology Case Reports Pub Date : 2024-07-23 DOI: 10.1016/j.mmcr.2024.100664
Leonard Farrugia , Veronica Baston , Laura Burfield , Lucy Melly , Andrew M. Borman , Abhijit M. Bal
{"title":"Cutaneous Purpureocillium lilacinum and Fusarium coinfection in a heart transplant recipient","authors":"Leonard Farrugia ,&nbsp;Veronica Baston ,&nbsp;Laura Burfield ,&nbsp;Lucy Melly ,&nbsp;Andrew M. Borman ,&nbsp;Abhijit M. Bal","doi":"10.1016/j.mmcr.2024.100664","DOIUrl":"10.1016/j.mmcr.2024.100664","url":null,"abstract":"<div><p><em>Purpureocillium lilacinum</em> and <em>Fusarium</em> species are increasingly recognized as significant opportunistic fungal pathogens. We report a rare case of co-infection in a 63-year old heart transplant recipient presenting with nodular skin lesions, treated successfully with voriconazole. We highlight the importance of being vigilant about co-infection with moulds as it impacts on the selection of appropriate antifungal agents. 2012 Elsevier Ltd. All rights reserved.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"45 ","pages":"Article 100664"},"PeriodicalIF":1.6,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000381/pdfft?md5=01798f3bc582cd8922b052dc413bc4d9&pid=1-s2.0-S2211753924000381-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141840894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An unexpected opportunist: Magnusiomyces capitatus infection in an immunocompetent patient 意想不到的机会主义者一名免疫功能正常患者的帽状木兰霉菌感染。
IF 1.6
Medical Mycology Case Reports Pub Date : 2024-07-23 DOI: 10.1016/j.mmcr.2024.100663
Mohammad Bosaeed , Rana Ayesh Alshehri , Danah Abdullah Albarrak , Tauseef Sharif , Majed Alghamdi , Abdullah Abdulrahman Alsunidy
{"title":"An unexpected opportunist: Magnusiomyces capitatus infection in an immunocompetent patient","authors":"Mohammad Bosaeed ,&nbsp;Rana Ayesh Alshehri ,&nbsp;Danah Abdullah Albarrak ,&nbsp;Tauseef Sharif ,&nbsp;Majed Alghamdi ,&nbsp;Abdullah Abdulrahman Alsunidy","doi":"10.1016/j.mmcr.2024.100663","DOIUrl":"10.1016/j.mmcr.2024.100663","url":null,"abstract":"<div><p><em>Magnusiomyces capitatus</em> is an uncommon opportunistic fungal pathogen primarily affecting immunocompromised individuals. While rare, cases have been reported in immunocompetent patients. We present a documented case of <em>Magnusiomyces capitatus</em> invasive infection in an immunocompetent patient with no previous medical history. This case shows that invasive fungal infections by <em>Magnusiomyces capitatus</em> might affect even the immunocompetent patients.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"45 ","pages":"Article 100663"},"PeriodicalIF":1.6,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S221175392400037X/pdfft?md5=db76f45dc44a1214698ac567617ff9f0&pid=1-s2.0-S221175392400037X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141849283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fatal misdiagnosis of progressive disseminated histoplasmosis 进行性播散组织胞浆菌病的致命误诊
IF 1.6
Medical Mycology Case Reports Pub Date : 2024-07-23 DOI: 10.1016/j.mmcr.2024.100662
Anthi Vasilopoulou , Marina Spaho , Paschalis Theotokis , Alexandra Grekou , Soultana Meditskou , Maria Eleni Manthou
{"title":"Fatal misdiagnosis of progressive disseminated histoplasmosis","authors":"Anthi Vasilopoulou ,&nbsp;Marina Spaho ,&nbsp;Paschalis Theotokis ,&nbsp;Alexandra Grekou ,&nbsp;Soultana Meditskou ,&nbsp;Maria Eleni Manthou","doi":"10.1016/j.mmcr.2024.100662","DOIUrl":"10.1016/j.mmcr.2024.100662","url":null,"abstract":"<div><p>Disseminated histoplasmosis is the form of a mycosis caused by the fungus <em>Histoplasma capsulatum</em> that mainly occurs in immunosuppressed hosts, usually with non-specific symptoms. In non-endemic areas, where the disease is rarely involved in the differential diagnosis, a delay in treatment may lead to severe medical complications. Due to the rising prevalence of disseminated histoplasmosis in these areas, a thorough medical history is regarded as the decisive factor in prompt diagnosis of the disease.</p><p>We, herein, report the case of an immunocompetent Greek farmer with disseminated histoplasmosis whose condition was initially misdiagnosed, and the consequential inadequate treatment led to his death.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"45 ","pages":"Article 100662"},"PeriodicalIF":1.6,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000368/pdfft?md5=3cef68843bbea6c2a0db8be12687cdfe&pid=1-s2.0-S2211753924000368-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141843462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recurrent Mucor indicus central venous catheter infection in a five year old child on long term parenteral nutrition for short gut syndrome: could gut translocation be responsible? 一名因短肠综合征接受长期肠外营养的五岁儿童反复发生吲哚粘菌中心静脉导管感染：肠道转位可能是原因吗？
IF 1.6
Medical Mycology Case Reports Pub Date : 2024-07-14 DOI: 10.1016/j.mmcr.2024.100661
Sarah Allen
{"title":"Recurrent Mucor indicus central venous catheter infection in a five year old child on long term parenteral nutrition for short gut syndrome: could gut translocation be responsible?","authors":"Sarah Allen","doi":"10.1016/j.mmcr.2024.100661","DOIUrl":"10.1016/j.mmcr.2024.100661","url":null,"abstract":"<div><p>A five year old girl with life-long TPN dependence for short gut syndrome presented with two episodes of non-fatal <em>Mucor indicus</em> central line associated blood stream infection (CLABSI). Each episode occurred fifteen months apart, without any evidence of ongoing mould infection whilst off antifungal therapy in the intervening time period. Both episodes were treated with removal of the infected central venous catheter (CVC) and 6 weeks of intravenous liposomal amphotericin B and/or posaconazole, with good clinical, microbiological, and radiological response. The possibility of gut translocation is supported by the repeated isolation of <em>Mucor indicus</em> in cases of intestinal mucormycosis. To our knowledge, this is the first case of recurrent episodes of blood culture positive mucormycosis in a single patient. <em>Mucor indicus</em> blood stream infection may differ significantly from invasive mucormycosis caused by other species.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"45 ","pages":"Article 100661"},"PeriodicalIF":1.6,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000356/pdfft?md5=777b7488e21e477ea8f8bc1581afae21&pid=1-s2.0-S2211753924000356-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141690265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case of fungal peritonitis in a patient with paramalignant ascites 一例患有副恶性腹水的真菌性腹膜炎患者
IF 1.6
Medical Mycology Case Reports Pub Date : 2024-07-14 DOI: 10.1016/j.mmcr.2024.100660
Julia M. Berger , Felix Lötsch , Anna S. Berghoff , Wolfgang W. Lamm , Matthias Preusser , Georg Jeryczynski
{"title":"A case of fungal peritonitis in a patient with paramalignant ascites","authors":"Julia M. Berger ,&nbsp;Felix Lötsch ,&nbsp;Anna S. Berghoff ,&nbsp;Wolfgang W. Lamm ,&nbsp;Matthias Preusser ,&nbsp;Georg Jeryczynski","doi":"10.1016/j.mmcr.2024.100660","DOIUrl":"10.1016/j.mmcr.2024.100660","url":null,"abstract":"<div><p>Here, we present the case of a patient with a metastatic neuroendocrine tumor with cytologically negative ascites treated for spontaneous bacterial peritonitis (SBP). Ascitic cultures remained negative for bacterial growth but were positive for <em>Candida albicans</em> 8 days after SBP diagnosis. ß-D-glucan was only positive in ascites, while being negative in blood. Blood cultures remained negative throughout the whole admission. Fungal peritonitis presumably originated from an impending bowl perforation or an increasing vascular permeability caused by an increase in VEGF secondary to diffuse infiltration by the underlying malignant disease.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"45 ","pages":"Article 100660"},"PeriodicalIF":1.6,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000344/pdfft?md5=92876b989cdd2c15a0d13644baf0cb88&pid=1-s2.0-S2211753924000344-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141708727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rare case of early neonatal sepsis caused by Candida krusei successfully treated with voriconazole 用伏立康唑成功治疗由克鲁塞念珠菌引起的新生儿早期败血症的罕见病例
IF 1.6
Medical Mycology Case Reports Pub Date : 2024-07-09 DOI: 10.1016/j.mmcr.2024.100659
Shashi Bhushan , Supriya Mahajan , Aditya Sen
{"title":"Rare case of early neonatal sepsis caused by Candida krusei successfully treated with voriconazole","authors":"Shashi Bhushan ,&nbsp;Supriya Mahajan ,&nbsp;Aditya Sen","doi":"10.1016/j.mmcr.2024.100659","DOIUrl":"https://doi.org/10.1016/j.mmcr.2024.100659","url":null,"abstract":"<div><p>This study reports a case of multidrug resistant <em>Candida krusei</em> as the cause of early neonatal sepsis in a term small-for-gestational age neonate weighing 1680 g that successfully responded to voriconazole therapy. Both blood culture and urine culture of the neonate sent on day 4 and day 8 respectively showed Gram positive oval budding yeast cells on Gram staining which was confirmed as <em>C. krusei</em> susceptible only to voriconazole by Vitek 2 Compact (Biomérieux, France) automated system. Voriconazole was given for fourteen days leading to good clinical response with microbiological clearance of fungus from blood and no side-effects.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"45 ","pages":"Article 100659"},"PeriodicalIF":1.6,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000332/pdfft?md5=ab1b6989634d82689ea5cca976748fbd&pid=1-s2.0-S2211753924000332-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141605968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Disseminated histoplasmosis: Long journey of a febrile young man 播散性组织胞浆菌病一名发热青年的漫长旅程
IF 1.6
Medical Mycology Case Reports Pub Date : 2024-07-08 DOI: 10.1016/j.mmcr.2024.100658
Sudip Kumar Banik , Chowdhury Adnan Sami , Md Mizanur Rahman Khan , Shohael Mahmud Arafat , Abed Hussain Khan
{"title":"Disseminated histoplasmosis: Long journey of a febrile young man","authors":"Sudip Kumar Banik ,&nbsp;Chowdhury Adnan Sami ,&nbsp;Md Mizanur Rahman Khan ,&nbsp;Shohael Mahmud Arafat ,&nbsp;Abed Hussain Khan","doi":"10.1016/j.mmcr.2024.100658","DOIUrl":"https://doi.org/10.1016/j.mmcr.2024.100658","url":null,"abstract":"<div><p>A 19-year-old non-diabetic, non-HIV male presented with eighteen months of fever, weight loss, skin rash and lymphadenopathy. He was treated with anti-tubercular medication for more than twelve months in multiple institutions based on repeated biopsy reports of lymph nodes showing granuloma suggestive of tuberculosis. Before he was diagnosed at Bangabandhu Sheikh Mujib Medical University (BSMMU) with disseminated histoplasmosis at eighteen months of his disease, he already lost twenty kg weight, developed multiple small joint pain, back pain, and cough along with previously mentioned symptoms. Extensive investigations at BSMMU revealed biopsy material from multiple sites showed noncaseating granulomas with Periodic acid-Schiff (PAS) stain positive for budding oval yeast cells, and fungal culture revealed growth of dimorphic fungus suggestive of Histoplasma after three weeks. After treatment with intravenous liposomal amphotericin B with continuous itraconazole, the patient's fever completely subsided, his well-being improved, joint pain reduced, started to gain weight, and skin lesions started to heal. This case serves as a significant reminder that it is imperative to consider alternative diagnoses in patients who fail to show improvement with conventional antitubercular treatment.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"45 ","pages":"Article 100658"},"PeriodicalIF":1.6,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000320/pdfft?md5=3da91110ff935c480c1bf29b4827205c&pid=1-s2.0-S2211753924000320-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141594182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Malassezia furfur bloodstream infection: still a diagnostic challenge in clinical practice 糠秕马拉色菌血流感染：仍是临床实践中的诊断难题
IF 1.6
Medical Mycology Case Reports Pub Date : 2024-07-03 DOI: 10.1016/j.mmcr.2024.100657
Rosalba Petruccelli , Terenzio Cosio , Valeria Camicia , Carlotta Fiorilla , Roberta Gaziano , Cartesio D'Agostini
{"title":"Malassezia furfur bloodstream infection: still a diagnostic challenge in clinical practice","authors":"Rosalba Petruccelli ,&nbsp;Terenzio Cosio ,&nbsp;Valeria Camicia ,&nbsp;Carlotta Fiorilla ,&nbsp;Roberta Gaziano ,&nbsp;Cartesio D'Agostini","doi":"10.1016/j.mmcr.2024.100657","DOIUrl":"https://doi.org/10.1016/j.mmcr.2024.100657","url":null,"abstract":"<div><p>The opportunistic fungus <em>Malassezia furfur</em> (<em>M. furfur</em>) can cause either cutaneous or systemic infections. We report a case of <em>M. furfur</em> fungemia in a 22-year-old male with T-cell Acute Lymphoblastic Leukemia (T-ALL) who developed concomitant <em>Bacillus cereus</em> (<em>B. cereus</em>) septicemia. The fungal infection was diagnosed by microscopic examination and culture-based methods, while automated blood culture systems and molecular approaches failed in identifying the fungus. Despite appropriate therapy, the patient died 18 days after the hospitalization.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"45 ","pages":"Article 100657"},"PeriodicalIF":1.6,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000319/pdfft?md5=597966c6ac43ef2d4fda19572fb715eb&pid=1-s2.0-S2211753924000319-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141541373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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