Olga S. Tatarinova , Caroline L. Furness , Andrew M. Borman , Joy Barber , Nagarajan Muthialu , Laura Ferreras-Antolin
{"title":"Neosartorya udagawae pulmonary infection requiring a surgical treatment in a paediatric haematopoietic progenitor cell recipient","authors":"Olga S. Tatarinova , Caroline L. Furness , Andrew M. Borman , Joy Barber , Nagarajan Muthialu , Laura Ferreras-Antolin","doi":"10.1016/j.mmcr.2024.100645","DOIUrl":"https://doi.org/10.1016/j.mmcr.2024.100645","url":null,"abstract":"<div><p><em>Neosartorya udagawae</em> is a known cause of fungal infection in humans and animals. It is found to be more refractory to antifungal treatment in comparison to other <em>Aspergillus</em> species. With this report we present a case of proven invasive infection with <em>Neosartorya udagawae</em> in a child with chronic myeloid leukaemia after haematopoietic stem cell transplant. The patient received several lines of antifungal therapy including dual therapy appropriate to the antifungal susceptibility profile with progression of the invasive fungal disease requiring left lung upper lobe lobectomy. The case emphasizes the importance of early biopsy with antifungal susceptibility testing for targeted therapy and demonstrates the potential requirement for surgical management in addition to appropriate antifungal treatment.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"44 ","pages":"Article 100645"},"PeriodicalIF":2.2,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000198/pdfft?md5=01f8bef143761a16b40d0a7ee107627d&pid=1-s2.0-S2211753924000198-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140535590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nakul Dar , Abigail Wills , Scott Berg , Sarah E. Gradecki , Thomas G. Cropley , Darren Guffey
{"title":"Cutaneous mucormycosis with suspected dissemination in a patient with metastatic adrenocortical carcinoma","authors":"Nakul Dar , Abigail Wills , Scott Berg , Sarah E. Gradecki , Thomas G. Cropley , Darren Guffey","doi":"10.1016/j.mmcr.2024.100646","DOIUrl":"https://doi.org/10.1016/j.mmcr.2024.100646","url":null,"abstract":"<div><p>Mucormycosis is a frequently lethal fungal infection that most commonly affects patients with poorly controlled diabetes or other immunosuppressed states. We report the case of a suspected disseminated <em>Rhizopus</em> infection in a patient who was pursuing naturopathic treatment including mud baths for metastatic adrenocortical carcinoma. He was empirically treated with liposomal amphotericin B but opted to stop treatment following multiorgan failure. The patient passed away on the tenth day of his hospital admission.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"44 ","pages":"Article 100646"},"PeriodicalIF":2.2,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000204/pdfft?md5=8ac018c49c6e2c100c5e8984ee019d5d&pid=1-s2.0-S2211753924000204-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140540078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Traumatic implantation keratitis caused by Schizophyllum commune in Central India","authors":"Anand Kumar Maurya , Sweta Kumari , Karuna Tadepalli , Bhavna Sharma , Arati Bhadade","doi":"10.1016/j.mmcr.2024.100644","DOIUrl":"https://doi.org/10.1016/j.mmcr.2024.100644","url":null,"abstract":"<div><p>We present two cases with a history of trauma to the cornea and after a few days patients developed symptoms of corneal ulcers with one showing hypopyon as well. Due to strong suspicion of fungal keratitis both cases were treated with topical and intravenously voriconazole. Fungal culture showed white fluffy growth which was identified as <em>Schizophyllum commune</em> by conventional and molecular methods. In both cases surgical intervention was essential. Therapeutic keratoplasty was done in both cases but failed. Unfortunately, both patients lost vision in the affected eyes.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"44 ","pages":"Article 100644"},"PeriodicalIF":2.2,"publicationDate":"2024-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000186/pdfft?md5=95da3df753532c43f9682cc7ba7b6e7f&pid=1-s2.0-S2211753924000186-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140208995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christopher Skinner , Rachel Allavena , Karon Hoffmann , Mirrim Kelly-Bosma , Sarah Kidd , Christine Thomson
{"title":"Disseminated Rasamsonia argillacea complex infection presenting as intraventricular brain hemorrhage in a German shepherd dog in Australia","authors":"Christopher Skinner , Rachel Allavena , Karon Hoffmann , Mirrim Kelly-Bosma , Sarah Kidd , Christine Thomson","doi":"10.1016/j.mmcr.2024.100641","DOIUrl":"https://doi.org/10.1016/j.mmcr.2024.100641","url":null,"abstract":"<div><p>A German Shepherd Dog diagnosed with <em>Rasamsonia argillacea</em> based on fungal culture and DNA sequencing, is the first documented case in Australia, and the Southern Hemisphere. This species is part of <em>R. argillacea</em> complex, which is an emerging concern in immunocompromised human and veterinary patients. Intraventricular brain hemorrhage, noted on MRI, has not been reported previously in a dog with fungal encephalitis. The patient was euthanized due to progression of clinical signs before a final diagnosis was made, so no treatment was attempted in this case.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"44 ","pages":"Article 100641"},"PeriodicalIF":2.2,"publicationDate":"2024-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000150/pdfft?md5=d595d3cc7e0aa03c72b650418fa3e159&pid=1-s2.0-S2211753924000150-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140134644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Challenging frontiers: Canine sporotrichosis due to Sporothrix brasiliensis, first case in Chile","authors":"Ailén Dumont , Carlos González , Belén Rivera , Isidora Mercy , Pamela Thomson","doi":"10.1016/j.mmcr.2024.100632","DOIUrl":"https://doi.org/10.1016/j.mmcr.2024.100632","url":null,"abstract":"<div><p>We report the first case of <em>Sporothrix brasiliensis</em> in a dog at Santiago, Chile. From an initial biopsy obtained from the patient, a histopathological study was performed that oriented a fungal infection. The molecular diagnosis from the isolated colony confirmed the identity of the <em>S. brasiliensis</em> agent. Although the literature indicates itraconazole as the first treatment option, the patient was treated with terbinafine followed by itraconazole, without achieving a clinical cure. <em>S. brasiliensis</em> that spread rapidly in Latin America, hence highlight the importance of timely diagnosis that contribute to maintaining human and animal health.</p><p>2012 Elsevier Ltd. All rights reserved.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"44 ","pages":"Article 100632"},"PeriodicalIF":2.2,"publicationDate":"2024-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S221175392400006X/pdfft?md5=276cd16a4fb0f17dcec602eb8fc24cea&pid=1-s2.0-S221175392400006X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140208994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sara Harrar , Nidae Mimouni , Rabie Kharchi , Imad Abkari , Awatif El Hakkouni
{"title":"Challenges in the management of severe cutaneous mucormycosis: A case of rapid progression in uncontrolled diabetes mellitus with polymicrobial implications","authors":"Sara Harrar , Nidae Mimouni , Rabie Kharchi , Imad Abkari , Awatif El Hakkouni","doi":"10.1016/j.mmcr.2024.100643","DOIUrl":"https://doi.org/10.1016/j.mmcr.2024.100643","url":null,"abstract":"<div><p>Mucormycosis, a rare but life-threatening fungal infection, poses significant challenges in clinical management, particularly in patients with uncontrolled diabetes mellitus. This case report presents the clinical journey of a 44-year-old woman who developed a rapidly progressing Mucorales infection following a domestic knife injury. Her condition, complicated by diabetic ketoacidosis and co-infection with <em>Candida albicans</em>, led to severe hand phlegm and sepsis. Despite aggressive intervention, the infection continued to advance, ultimately resulting in the patient’s demise.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"44 ","pages":"Article 100643"},"PeriodicalIF":2.2,"publicationDate":"2024-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000174/pdfft?md5=9a22a13d66acaf6b60a008c0495b09d6&pid=1-s2.0-S2211753924000174-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140113275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mariana Lucy Mesquita Ramos , Vanessa Brito de Souza Rabello , Erica Aparecida dos Santos Ribeiro da Silva , Maria Cristina da Silva Lourenço , Rodrigo Almeida-Paes , Susana Frases
{"title":"Beyond conventional approaches: Enhancing photodynamic therapy for refractory feline sporotrichosis caused by Sporothrix brasiliensis","authors":"Mariana Lucy Mesquita Ramos , Vanessa Brito de Souza Rabello , Erica Aparecida dos Santos Ribeiro da Silva , Maria Cristina da Silva Lourenço , Rodrigo Almeida-Paes , Susana Frases","doi":"10.1016/j.mmcr.2024.100642","DOIUrl":"https://doi.org/10.1016/j.mmcr.2024.100642","url":null,"abstract":"<div><p>Male cat, 2 years old, with a refractory infection by Sporothrix brasiliensis, presents a single nodular lesion in the left auricular pavilion. To confirm the diagnosis, cytology, fungal culture, antifungal susceptibility test, molecular analysis, and, to aid in the differential diagnosis, bacterial culture, antibiogram, and histopathology of the lesion were performed. In the absence of therapeutic success with conventional antifungals, photodynamic therapy (PDT) was introduced, demonstrating a satisfactory response in the sixth treatment session.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"44 ","pages":"Article 100642"},"PeriodicalIF":2.2,"publicationDate":"2024-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000162/pdfft?md5=ca5199cb5a76d28fcd643c39e38fd5bb&pid=1-s2.0-S2211753924000162-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140134643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vítor Falcão de Oliveira, Mariane Taborda, Adriana Satie Gonçalves Kono Magri, Anna Sara Shafferman Levin, Marcello Mihailenko Chaves Magri
{"title":"Paracoccidioidomycosis after eyebrow micropigmentation: Unusual reactivation or a new form of transmission by cutaneous inoculation?","authors":"Vítor Falcão de Oliveira, Mariane Taborda, Adriana Satie Gonçalves Kono Magri, Anna Sara Shafferman Levin, Marcello Mihailenko Chaves Magri","doi":"10.1016/j.mmcr.2024.100639","DOIUrl":"10.1016/j.mmcr.2024.100639","url":null,"abstract":"<div><p>We report a case of unusual paracoccidioidomycosis reactivation after eyebrow micropigmentation in a Brazilian patient. The cutaneous lesion was the only clinical manifestation. Direct cutaneous inoculation in dermal tissues with <em>Paracoccidioides</em> sp. is extremely rare, explaining why paracoccidioidomycosis is not classically considered a cutaneous implantation mycosis.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"44 ","pages":"Article 100639"},"PeriodicalIF":2.2,"publicationDate":"2024-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000137/pdfft?md5=b98048f26a05417f0c09139c4f15dbd8&pid=1-s2.0-S2211753924000137-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140086009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kiran G. Kulirankal , Ann Mary , Merlin Moni , Gopal S. Pillai , Dipu T. Sathyapalan
{"title":"Long-term survival following medical management of Aspergillus endocarditis with dissemination as a consequence of steroid therapy in severe COVID-19 pneumonia","authors":"Kiran G. Kulirankal , Ann Mary , Merlin Moni , Gopal S. Pillai , Dipu T. Sathyapalan","doi":"10.1016/j.mmcr.2024.100638","DOIUrl":"https://doi.org/10.1016/j.mmcr.2024.100638","url":null,"abstract":"<div><p>A male in his 40's with no known comorbidities developed severe COVID-19 pneumonia and received a four-week course of methylprednisolone. The patient subsequently developed disseminated <em>Aspergillus</em> endocarditis, manifesting as multiple organ involvement including the heart, eyes, and brain. Despite the poor prognosis generally associated with fungal endocarditis, the patient survived following aggressive medical management with a combination of liposomal amphotericin b and voriconazole therapy and is now doing well for over two years and is off antifungal therapy for a year.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"43 ","pages":"Article 100638"},"PeriodicalIF":2.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000125/pdfft?md5=deb989cc37b52c73671299c8f5b1b1f6&pid=1-s2.0-S2211753924000125-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140052762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Phuong Anh Ton Nu , Thi Minh Chau Ngo , Cao Le Chi , Thị Bich Thao Do , Giang Tran Thi , Thị Ngoc Thuy Ha , Phuoc Vinh Nguyen , Minh Tam Le
{"title":"Three cases of vulvovaginal candidiasis due to Candida nivariensis","authors":"Phuong Anh Ton Nu , Thi Minh Chau Ngo , Cao Le Chi , Thị Bich Thao Do , Giang Tran Thi , Thị Ngoc Thuy Ha , Phuoc Vinh Nguyen , Minh Tam Le","doi":"10.1016/j.mmcr.2024.100640","DOIUrl":"https://doi.org/10.1016/j.mmcr.2024.100640","url":null,"abstract":"<div><p><em>Candida nivariensis</em> is emerging as a highly resistant species of the <em>Candida glabrata</em> complex causing invasive and mucocutaneous infections. In this study, three cases of vulvovaginal candidiasis caused by <em>C. nivariensis</em> are described and identified by Internal Transcribed Spacer 1–2 sequencing. All isolates were susceptible in vitro to anidulafungin, micafungin, caspofungin, 5-flucytosine, posaconazole, voriconazole, itraconazole, amphotericin B, and showed dose-dependent susceptibility to fluconazole. In two patients, three doses of oral fluconazole were effective, while one patient developed clinical fluconazole resistance with a new relapse after 6 months. Increasing the weekly dose of fluconazole showed to be effective in this patient.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"43 ","pages":"Article 100640"},"PeriodicalIF":2.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000149/pdfft?md5=019b1b5c0a4940ad3af8305bddb2bc56&pid=1-s2.0-S2211753924000149-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140014139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}