Laman Rahimli , Jon Salmanton-García , Philipp Kasper , Michaela Simon , Oliver A. Cornely , Jannik Stemler
{"title":"坏死性胰腺炎伴有白念珠菌和泛耐药念珠菌引起的侵袭性念珠菌病和念珠菌血症","authors":"Laman Rahimli , Jon Salmanton-García , Philipp Kasper , Michaela Simon , Oliver A. Cornely , Jannik Stemler","doi":"10.1016/j.mmcr.2024.100636","DOIUrl":null,"url":null,"abstract":"<div><p>We report on a 64-year-old man with necrotizing pancreatitis related, invasive candidiasis, and candidemia. Despite a multidisciplinary management including antifungal therapy, endoscopic interventions and surgery, the patients’ infection progressed and lead to colon perforation, retroperitoneal abscess formation, and polymicrobial bloodstream infections. Resistance to echinocandins in <em>Candida glabrata</em> further complicated the course. This report emphasizes the need for vigilant monitoring and exploring alternative therapeutic approaches for patients in critical conditions.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"43 ","pages":"Article 100636"},"PeriodicalIF":1.6000,"publicationDate":"2024-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000101/pdfft?md5=39373b7d47b4cf3bb8d8df2754e50021&pid=1-s2.0-S2211753924000101-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Necrotizing pancreatitis with invasive candidiasis and candidemia due to Candida albicans and pan-echinocandin-resistant Candida glabrata\",\"authors\":\"Laman Rahimli , Jon Salmanton-García , Philipp Kasper , Michaela Simon , Oliver A. Cornely , Jannik Stemler\",\"doi\":\"10.1016/j.mmcr.2024.100636\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>We report on a 64-year-old man with necrotizing pancreatitis related, invasive candidiasis, and candidemia. Despite a multidisciplinary management including antifungal therapy, endoscopic interventions and surgery, the patients’ infection progressed and lead to colon perforation, retroperitoneal abscess formation, and polymicrobial bloodstream infections. Resistance to echinocandins in <em>Candida glabrata</em> further complicated the course. This report emphasizes the need for vigilant monitoring and exploring alternative therapeutic approaches for patients in critical conditions.</p></div>\",\"PeriodicalId\":51724,\"journal\":{\"name\":\"Medical Mycology Case Reports\",\"volume\":\"43 \",\"pages\":\"Article 100636\"},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2024-02-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2211753924000101/pdfft?md5=39373b7d47b4cf3bb8d8df2754e50021&pid=1-s2.0-S2211753924000101-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Medical Mycology Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2211753924000101\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, RESEARCH & EXPERIMENTAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical Mycology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2211753924000101","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
Necrotizing pancreatitis with invasive candidiasis and candidemia due to Candida albicans and pan-echinocandin-resistant Candida glabrata
We report on a 64-year-old man with necrotizing pancreatitis related, invasive candidiasis, and candidemia. Despite a multidisciplinary management including antifungal therapy, endoscopic interventions and surgery, the patients’ infection progressed and lead to colon perforation, retroperitoneal abscess formation, and polymicrobial bloodstream infections. Resistance to echinocandins in Candida glabrata further complicated the course. This report emphasizes the need for vigilant monitoring and exploring alternative therapeutic approaches for patients in critical conditions.