Yasser Al-Ghabra , Mohammad Hamdi , Ahmad Alkheder , Ahmad Kammasha , Shams Shamso , Adham Bader Aldeen Mohsen
{"title":"Palatal mucormycosis in a 2-month-old child: A very rare case report and a literature review","authors":"Yasser Al-Ghabra , Mohammad Hamdi , Ahmad Alkheder , Ahmad Kammasha , Shams Shamso , Adham Bader Aldeen Mohsen","doi":"10.1016/j.mmcr.2024.100628","DOIUrl":null,"url":null,"abstract":"<div><p>A 2-month-old Syrian male child presented with a large blackish ulcerating lesion on his hard palate, along with fever, diarrhea, vomiting, and milk regurgitation from the nose. The child was diagnosed with palatal mucormycosis by histopathology and underwent treatment with liposomal amphotericin B and surgical debridement. However, despite treatment, the child's condition deteriorated, and he died from respiratory failure. An underlying immunodeficiency was not diagnosed, but the family history revealed several deaths of the child's siblings at very early ages due to poorly documented complicated metabolic syndromes. An autopsy was refused by the parents due to cultural reasons.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"43 ","pages":"Article 100628"},"PeriodicalIF":1.6000,"publicationDate":"2024-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000022/pdfft?md5=4df4570033271019c97490a871754653&pid=1-s2.0-S2211753924000022-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical Mycology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2211753924000022","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
引用次数: 0
Abstract
A 2-month-old Syrian male child presented with a large blackish ulcerating lesion on his hard palate, along with fever, diarrhea, vomiting, and milk regurgitation from the nose. The child was diagnosed with palatal mucormycosis by histopathology and underwent treatment with liposomal amphotericin B and surgical debridement. However, despite treatment, the child's condition deteriorated, and he died from respiratory failure. An underlying immunodeficiency was not diagnosed, but the family history revealed several deaths of the child's siblings at very early ages due to poorly documented complicated metabolic syndromes. An autopsy was refused by the parents due to cultural reasons.
一名2个月大的叙利亚男童因硬腭上出现大面积黑色溃疡,伴有发烧、腹泻、呕吐和鼻腔反流牛奶而就诊。经组织病理学检查,该患儿被诊断为腭粘液瘤病,并接受了两性霉素 B 脂质体治疗和手术清创。然而,尽管进行了治疗,孩子的病情还是恶化了,最后死于呼吸衰竭。虽然没有诊断出潜在的免疫缺陷,但家族病史显示,该患儿的几个兄弟姐妹在很小的时候就因复杂的代谢综合征而死亡。由于文化原因,父母拒绝进行尸检。