International Journal of Medical Research & Health Sciences最新文献_第4页

change of BDNF expression in traumatic brain injury after Kaempferia galanga L. administration 山柰对创伤性脑损伤脑组织中BDNF表达的影响

International Journal of Medical Research & Health Sciences Pub Date : 2022-02-04 DOI: 10.21744/ijhms.v5n1.1847

A. Kurniawan, A. Turchan, Budi Utomo, M. Parenrengi, D. Fauziah

{"title":"change of BDNF expression in traumatic brain injury after Kaempferia galanga L. administration","authors":"A. Kurniawan, A. Turchan, Budi Utomo, M. Parenrengi, D. Fauziah","doi":"10.21744/ijhms.v5n1.1847","DOIUrl":"https://doi.org/10.21744/ijhms.v5n1.1847","url":null,"abstract":"BDNF has potent effects on neural synapses and its pathway affects cell survival and other biological processes. Kaempferia galanga L. has many active substances with antioxidant and anti-inflammatory effects. We analyzes BDNF in four different group of Wistar rats (Ratus novergicus) into Groups A (no trauma & extract), B (with trauma & no extract), C (with trauma and 600 mg/kgbw extract), and D (with trauma and 1200 mg/kgbw extract). Groups B, C, and D are further divided into those who had their BDNF measured on 24- (B24, C24, and D24) and 48-hours. BDNF expression were found to be statistically significant between Group A with both B24 (p = 0,009) and D24 (p = 0,009) on the 24-hour post-trauma decapitation analysis. On the 48 hours after trauma and extract administration, Group B48 (p = 0,002), C48 (p = <0,001), and D48 (p <0,001) were found to be significantly different with Group A. The administration of Kaempferia galanga L. extract can be considered as an option in increasing brain BDNF levels which are neuroprotective. Larger and specific studies are needed to determine the appropriate dose and duration.","PeriodicalId":51699,"journal":{"name":"International Journal of Medical Research & Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80592428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinicopathological profile of clear cell renal cell carcinoma 透明细胞肾细胞癌的临床病理特征

International Journal of Medical Research & Health Sciences Pub Date : 2022-01-25 DOI: 10.21744/ijhms.v5n1.1846

Pamela Kusumadewi Putri Thaib, A. S. Rahaju

{"title":"Clinicopathological profile of clear cell renal cell carcinoma","authors":"Pamela Kusumadewi Putri Thaib, A. S. Rahaju","doi":"10.21744/ijhms.v5n1.1846","DOIUrl":"https://doi.org/10.21744/ijhms.v5n1.1846","url":null,"abstract":"Clear cell renal cell carcinoma (ccRCC) is the most common subtype of kidney cancer with aggressive behavior. Tumor stage and grade are important parameter in diagnosis. Data about the clinical and pathology profile of ccRCC in Indonesia is limited, therefore further information is needed. The study aimed to determine clinicopathologic profile of ccRCC in Soetomo Academic General Hospital (SAGH). This descriptive study was conducted retrospectively with cross-sectional approach. Clinical and histopathological archives of ccRCC specimen were retrieved during January 2016 to December 2020. The total number of ccRCC cases obtained was 38 cases, the most cases (11) occurred in 2016. The average of patient’s age was 55.64 years. Patients were predominantly male (71.1%), with a ratio to female 2.5:1. The tumors mostly filled the entire kidney, in 15 (39.5%) cases. Most pT stage distribution was pT2, in 15 (39.5%) cases. Most N stage distribution was N0, in 23 (60.5%) cases. Only 5 (13.2%) cases showed multiple pulmonary nodules which suspected to be metastatic (M1). The most common tumors grade was G4, in 17 (44.7%) cases. In conclusion, ccRCC patient were predominantly male, tumors mostly high grade, filled entire kidney, not penetrated renal capsule, and not metastasize to regional lymph nodes.","PeriodicalId":51699,"journal":{"name":"International Journal of Medical Research & Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91268119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 62

Comparison of the use of shock index and modified early obstetric warning score in COVID-19 obstetric emergency patients as ICU care parameters 休克指数与修正产科早期预警评分在COVID-19产科急诊患者中作为ICU护理参数的比较

International Journal of Medical Research & Health Sciences Pub Date : 2022-01-22 DOI: 10.21744/ijhms.v5n1.1844

S. Wahyuni, S. Chalid, N. Pelupessy, S. Arifuddin, Irfan Idris, A. N. Usman

{"title":"Comparison of the use of shock index and modified early obstetric warning score in COVID-19 obstetric emergency patients as ICU care parameters","authors":"S. Wahyuni, S. Chalid, N. Pelupessy, S. Arifuddin, Irfan Idris, A. N. Usman","doi":"10.21744/ijhms.v5n1.1844","DOIUrl":"https://doi.org/10.21744/ijhms.v5n1.1844","url":null,"abstract":"The physiological parameters included in the Modified Early Obstetric Warning Score (MEOWS) table have been selectively selected so that they cover all the standard observations in the NEWS table with the addition of several parameters that are specifically. The population in this study were all pregnant women who were in RSIA Siti Khadijah I Makassar and RSUP Dr. Wahidin Sudirohusodo Makassar. The results showed that there was no significant difference between the shock index and the incidence of shock (p=0.418). The difference in frequency between the shock index and the incidence of shock in the ICU was 1 patient who was pregnant. Based on shock index with high and low categories did not differ significantly (p=0.418). The data also shows that the frequency of pregnant women who are in shock is higher, namely 44 people (57.9%) compared to those who are not in shock, namely 32 people (42.1%). There was no significant difference between the shock index and the incidence of shock (p=0.112). The difference in frequency between the shock index and the incidence of shock in the ICU was 5 patients with pregnant women. Shock frequency based on the MEOWS index was not significantly different (p=0.112).","PeriodicalId":51699,"journal":{"name":"International Journal of Medical Research & Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84420993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 18

Analysis of understanding of midwife students of midwife care as the impact of online learning 分析助产士学生对助产士护理的理解作为在线学习的影响

International Journal of Medical Research & Health Sciences Pub Date : 2022-01-19 DOI: 10.21744/ijhms.v5n1.1834

Nursyahraeni Madika Rahman, Sutinah Made, A. N. Usman, Irfan Idris, A. Unde, Burhanuddin Bahar

{"title":"Analysis of understanding of midwife students of midwife care as the impact of online learning","authors":"Nursyahraeni Madika Rahman, Sutinah Made, A. N. Usman, Irfan Idris, A. Unde, Burhanuddin Bahar","doi":"10.21744/ijhms.v5n1.1834","DOIUrl":"https://doi.org/10.21744/ijhms.v5n1.1834","url":null,"abstract":"The purpose of this study was to analyze the understanding of midwifery students towards midwifery care as a result of online learning at the midwifery academy of Tahirah Al Baeti Bulukumba. This study is a quantitative descriptive study, a form of activity by measuring the level of understanding of students to family planning midwifery care as a result of online learning and probability sampling techniques with a total of 45 respondents. Analysis of data in this study is obtained from research instruments in the form of quantitative data. Quantitative data are obtained from the results of data processing case tests and surveys. The results of the study of Student Understanding Before and During the COVID-19 Pandemic on the creation of Family Planning Midwifery Care, namely an increase in understanding of the creation of family planning midwifery care by 20%, shows that students actively remain disciplined in carrying out learning activities through online, namely by self-study after online learning and able to understand the lecture materials provided by lecturers.","PeriodicalId":51699,"journal":{"name":"International Journal of Medical Research & Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84640580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Deep vein thrombosis prophylaxis use in traumatic brain injury patients in tropical climate 热带气候创伤性脑损伤患者深静脉血栓预防的应用

International Journal of Medical Research & Health Sciences Pub Date : 2022-01-19 DOI: 10.21744/ijhms.v5n1.1840

Akbar Wido, A. Bajamal, Tedy Apriawan, M. Parenrengi, Asra Al Fauzi

{"title":"Deep vein thrombosis prophylaxis use in traumatic brain injury patients in tropical climate","authors":"Akbar Wido, A. Bajamal, Tedy Apriawan, M. Parenrengi, Asra Al Fauzi","doi":"10.21744/ijhms.v5n1.1840","DOIUrl":"https://doi.org/10.21744/ijhms.v5n1.1840","url":null,"abstract":"Deep Vein Trombosis (DVT) is one of the extracranial complications after TBI. Prophylaxis DVT using on TBI reduce incidence and mortality. Climate variants of an area affect the risk of DVT. UV ray increasing synthesis of vitamin D and lowering risk of thrombus fomation. A systematic review and meta-analysis we performed according PRISMA guidelines. A through literature search was conducted on PubMed, Scopus, and Cochrane database. Total 3 publications match study criteria with 178 samples, without 144 samples and 34 samples with prophylaxis. The overall incidence is 5% (0-6.8%), without 6.25% (5.3-6.8%) and with prophylaxis 0%. No reported complications and 100% survival rate. The incidence of DVT in TBI in tropical climate is low on average 5% (0-6.8%). There was no difference in the outcome of DVT in TBI in tropical climate which given and without DVT prophylaxis. Asian races ethnic protective factor and UV ray exposure may contributed to the low of incidence rate. Prevention of DVT is still recommended for the use of prophylaxis, mechanical compression and early mobilization in cases of TBI to prevent the occurrence of DVT.","PeriodicalId":51699,"journal":{"name":"International Journal of Medical Research & Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85487262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 30

Effect of web-based she smart education models on adolescent girl’s knowledge, attitudes, and practice about obesity 网络智能教育模式对青春期少女肥胖知识、态度和行为的影响

International Journal of Medical Research & Health Sciences Pub Date : 2022-01-17 DOI: 10.21744/ijhms.v5n1.1832

A. Herliah, Y. S. Baso, Healthy Hidayanty, Syafruddin Syarif, A. Aminuddin, Burhanuddin Bahar

{"title":"Effect of web-based she smart education models on adolescent girl’s knowledge, attitudes, and practice about obesity","authors":"A. Herliah, Y. S. Baso, Healthy Hidayanty, Syafruddin Syarif, A. Aminuddin, Burhanuddin Bahar","doi":"10.21744/ijhms.v5n1.1832","DOIUrl":"https://doi.org/10.21744/ijhms.v5n1.1832","url":null,"abstract":"Obesity is a disorder characterized by excessive accumulation of body fat. The nutritional impact is more than just disturbing the aesthetics of appearance. Obesity (overweight and overweight) is a new chronic disorder that soon becomes a global pandemic that is quite difficult to control. To improve the knowledge, attitudes, and Practice of Adolescent Girls about obesity. Use Pre-Experiment with one group pre-test and post-test design. Sampling technique using purposive sampling and obtained a total of 47 respondents. The research was conducted in the Senior High School of 12 Makassar in September-October 2021. Data analysis using the McNemar test. The results of statistics showed that there is an influence on the use of the web-based She Smart education model of the knowledge and attitudes of Adolescent Girls with a value of p-value=0.008 (p<0.05). And there was no influence on the use of the web-based She Smart education model on the Practice of Adolescent Girls with a p-value of 0.453 (p>0.05). There is an influence on providing obesity education before and after intervention through web-based obesity education media in improving knowledge and attitudes but does not affect the Practice of adolescent girls in overcoming the problem of obesity.","PeriodicalId":51699,"journal":{"name":"International Journal of Medical Research & Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76497762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 29

Prolonged newborns and prolong pregnancy 延长新生儿和妊娠期

International Journal of Medical Research & Health Sciences Pub Date : 2022-01-14 DOI: 10.21744/ijhms.v5n1.1829

N. Ermatov, T. Bobomuratov, M.A. Sagdullaeva

引用次数: 0

effect of HIV/AIDS education prevention using web-based she smart on knowledge, attitudes, and practice in adolescent girls 基于网络的艾滋病预防教育对少女知识、态度和行为的影响

International Journal of Medical Research & Health Sciences Pub Date : 2022-01-14 DOI: 10.21744/ijhms.v5n1.1830

Komala Dewi Muslimin, Y. S. Baso, Healthy Hidayanty, Syafruddin Syarif, A. Aminuddin, Burhanuddin Bahar

{"title":"effect of HIV/AIDS education prevention using web-based she smart on knowledge, attitudes, and practice in adolescent girls","authors":"Komala Dewi Muslimin, Y. S. Baso, Healthy Hidayanty, Syafruddin Syarif, A. Aminuddin, Burhanuddin Bahar","doi":"10.21744/ijhms.v5n1.1830","DOIUrl":"https://doi.org/10.21744/ijhms.v5n1.1830","url":null,"abstract":"From year to year the number of cases of people with HIV/AIDS has increased. This increase is also experienced in Indonesia, where adolescents infected with HIV/AIDS show a number that tends to rise. It is characterized by a teenager's ignorance about reproductive health and knowledge of his sexual state. So many teenagers are at risk for early marriage problems, pregnancy, sexually transmitted infections, and also HIV/AIDS. To look at the influence of HIV/AIDS education on the knowledge, attitudes, and Practice of Adolescent girls. Use Pre-Experiment with one group pre-test and post-test design. Sampling technique using purposive sampling and obtained the number of 47 students. The research was conducted in Senior High School 12 Makassar in September-October 2021. Data analysis using the McNemar Test. And statistical test results showed there was an influence on the use of HIV/AIDS education using web-based She Smart on knowledge where p-value = 0,000, attitude with a value of p-value = 0.000, and no significant difference in action with p-value = 0.500. There is an influence on the use of web-based HIV/AIDS education using She Smart on knowledge and attitudes but no significant influence on actions before and after an intervention.","PeriodicalId":51699,"journal":{"name":"International Journal of Medical Research & Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87651498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Characteristics and pharmacological treatment options of delirium patients treated at Sanglah Central General Hospital 桑格拉中心总医院谵妄患者的特点和药物治疗选择

International Journal of Medical Research & Health Sciences Pub Date : 2022-01-13 DOI: 10.21744/ijhms.v5n1.1835

N. K. S. Diniari, L. Aryani

{"title":"Characteristics and pharmacological treatment options of delirium patients treated at Sanglah Central General Hospital","authors":"N. K. S. Diniari, L. Aryani","doi":"10.21744/ijhms.v5n1.1835","DOIUrl":"https://doi.org/10.21744/ijhms.v5n1.1835","url":null,"abstract":"Delirium is a syndrome characterized by disturbances of consciousness and cognition that occur acutely and fluctuate. Delirium can be caused by general medical conditions, drug users, sensory disturbances, polypharmacy, etc. The etiology of delirium is diverse and non-specific. The preference of pharmacological therapy in delirium is still a debate. Descriptive research with the retrospective cross-sectional method, using secondary data in medical records at the Sanglah Central General Hospital Denpasar for the period January 1, 2020, to December 31, 2020. Patients who were consulted were 166 people, with sex 57 people (34.3%) and 109 women (65.7%). The incidence of delirium in adults (20-59 years old) and elderly (age 60 years) is the highest with 51.2% and 45.1% respectively. One-third of 45 people (37.2%) had overlapping dementia. Most of the 142 people (85.5%) were experiencing significant life stress. The most common type of delirium was hyperactive delirium (74%). The underlying disease of delirium varies such as the cause of infection (24.1%), intracranial process (19%), malignancy 18.1%, cardiovascular (10.1%), endocrine disorders,(7.8%), kidney disorders (6%), and others in small percentages.","PeriodicalId":51699,"journal":{"name":"International Journal of Medical Research & Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74970436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 14

choice of surgical tactics for the treatment of children with destructive pathological dislocation of the hip after hematogenous osteomyelitis 儿童血液性骨髓炎后破坏性病理性髋关节脱位手术策略的选择

International Journal of Medical Research & Health Sciences Pub Date : 2021-12-29 DOI: 10.21744/ijhms.v5n1.1813

A. Djuraev, Khojaakhmed Shaykhislamovich Alpisbaev, Elyar Abduvalievich Tapilov

引用次数: 34