Deep vein thrombosis prophylaxis use in traumatic brain injury patients in tropical climate

Akbar Wido, A. Bajamal, Tedy Apriawan, M. Parenrengi, Asra Al Fauzi
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引用次数: 30

Abstract

Deep Vein Trombosis (DVT) is one of the extracranial complications after TBI. Prophylaxis DVT using on TBI reduce incidence and mortality. Climate variants of an area affect the risk of DVT. UV ray increasing synthesis of vitamin D and lowering risk of thrombus fomation. A systematic review and meta-analysis we performed according PRISMA guidelines. A through literature search was conducted on PubMed, Scopus, and Cochrane database. Total 3 publications match study criteria with 178 samples, without 144 samples and 34 samples with prophylaxis. The overall incidence is 5% (0-6.8%), without 6.25% (5.3-6.8%) and with prophylaxis 0%. No reported complications and 100% survival rate. The incidence of DVT in TBI in tropical climate is low on average 5% (0-6.8%). There was no difference in the outcome of DVT in TBI in tropical climate which given and without DVT prophylaxis. Asian races ethnic protective factor and UV ray exposure may contributed to the low of incidence rate.  Prevention of DVT is still recommended for the use of prophylaxis, mechanical compression and early mobilization in cases of TBI to prevent the occurrence of DVT.
热带气候创伤性脑损伤患者深静脉血栓预防的应用
深静脉血栓形成(Deep Vein trobosis, DVT)是创伤性脑损伤后的颅外并发症之一。预防性深静脉血栓栓塞治疗脑外伤可降低发病率和死亡率。一个地区的气候变化会影响DVT的风险。紫外线增加维生素D的合成,降低血栓形成的风险。我们根据PRISMA指南进行了系统回顾和荟萃分析。通过PubMed、Scopus和Cochrane数据库进行文献检索。共有3份出版物有178份样本符合研究标准,144份样本不符合研究标准,34份样本有预防措施。总发病率为5%(0-6.8%),无6.25%(5.3-6.8%),预防为0%。无并发症报告,生存率100%。热带气候TBI中DVT的发生率较低,平均为5%(0-6.8%)。在热带气候下,给予和未给予DVT预防的TBI患者的DVT结局没有差异。亚洲人种的民族保护因素和紫外线照射可能是导致发病率低的原因。预防深静脉血栓仍然被推荐使用预防,机械压迫和早期活动在TBI的情况下,以防止深静脉血栓的发生。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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