Journal of Frailty & Aging最新文献

{"title":"Prevalence of intrinsic capacity decline and its association with activities of daily living among pre-frail and frail older adults in a community-based geriatric services hub model.","authors":"Lydia Au, Izza Elyana Bte Azhar, Jer En Lee, Jasmine Shimin Lim, Alexa Lai, Bernice Mh Chua, Yu Ann Tan, Reshma A Merchant","doi":"10.1016/j.tjfa.2025.100105","DOIUrl":"10.1016/j.tjfa.2025.100105","url":null,"abstract":"<p><strong>Introduction: </strong>As Singapore's population rapidly ages, there is a growing need to proactively address frailty and intrinsic capacity (IC) decline to delay disability and preserve independence. This study aims to a) determine prevalence of IC decline in frail older patients referred to the geriatric service hub (GSH), stratified by age and frailty status and b) determine its association with activity of daily living (ADL).</p><p><strong>Methodology: </strong>A cross-sectional study was conducted from July 2019 to March 2022. Community-dwelling older adults (≥65 years) identified as pre-frail or frail in selected primary care clinics and eldercare centers were referred to the GSH for further evaluation. All participants received a comprehensive geriatric assessment, which included Clinical Frailty Scale (CFS) scoring and evaluation of six IC domains: locomotion, vitality, cognition, sensory (vision and hearing), psychological, and continence. Functional status was assessed using the Modified Barthel Index and self-reported ADL and instrumental ADL (IADL).</p><p><strong>Results: </strong>Among 372 participants, 52.2 % were aged 65-79 (old) and 47.8 % were ≥ 80 years (old-old). Approximately two-thirds were classified as CFS 4 or 5. IC decline was significantly more prevalent in the \"old-old\" group, especially in locomotion (94.4 %), vitality (94.5 %), cognition (68.4 %), vision (78.7 %), and hearing (33.1 %). Despite IC decline, up to two-thirds of participants remained independent or only mildly dependent in ADL. IC impairment increased progressively with advancing frailty and age. In multivariate logistic regression, moderate to severe ADL dependency was independently associated with impaired locomotion (aOR 5.105; 95 % CI 1.023-25.477) and vision impairment (aOR 2.607; 95 % CI 1.234-5.508).</p><p><strong>Conclusion: </strong>IC screening in primary care is a feasible and effective approach that may contribute to detection of early functional decline. The high burden of multidomain IC impairment, particularly among the oldest and most frail, supports the need for upstream, integrated, and age-inclusive screening and intervention strategies in community settings.</p>","PeriodicalId":51629,"journal":{"name":"Journal of Frailty & Aging","volume":"15 1","pages":"100105"},"PeriodicalIF":3.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12757629/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145745817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between diabetes and frailty, and the moderating role of sex in that association in older adults of the ELSA-Brasil study.","authors":"Elizabeth Leite Barbosa, Rosa Weiss Telles, Maria de Jesus Mendes da Fonseca, Maria Inês Schmidt, Sandhi Maria Barreto, Bruce Duncan, Rosane Harter Griep","doi":"10.1016/j.tjfa.2025.100115","DOIUrl":"10.1016/j.tjfa.2025.100115","url":null,"abstract":"<p><strong>Objective: </strong>to investigate the association of diabetes and its duration with frailty and evaluate the moderating effect of sex on that association in older adults.</p><p><strong>Methods: </strong>This cross-sectional study used data from the third visit (2017-2019) of the Estudo Longitudinal de Saúde do Adulto (ELSA-Brasil), a multicentre cohort of Brazilian civil servants. The data included were from 4886 participants aged ≥ 60 years. Diabetes was identified on the basis of self-reported diagnosis or laboratory test values. Frailty was evaluated on frailty phenotype criteria. Associations were estimated by way of multinomial regression models.</p><p><strong>Results: </strong>Adjusted final models showed that older adults classified as having diabetes were 116% more likely to show frailty, and 27% more likely to show pre-frailty, than persons without diabetes. Individuals with a diagnosis before baseline and those with that diagnosis at baseline or during follow-up until visit 3 were, respectively, 145% and 92% more likely to be classified as frail, and 35% and 21% more likely to be classified as pre-frail, than individuals without diabetes. No modification by a multiplier effect of sex was observed in the final models.</p><p><strong>Conclusions/interpretation: </strong>Older adults with diabetes returned greater odds of pre-frailty and frailty, and the odds were even greater in those with longer times since the diagnosis of diabetes, but sex did not modify those associations. These findings endorse the need for more frequent screening of older adults with diabetes with a view to early prevention and/or intervention.</p>","PeriodicalId":51629,"journal":{"name":"Journal of Frailty & Aging","volume":"15 1","pages":"100115"},"PeriodicalIF":3.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12757626/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145745714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"Vieni da Nonna Tua, Vieni!\" A commentary on the social construction of grandmothers and its impact on older women's lives.","authors":"Hélio José Coelho-Júnior, Riccardo Calvani, Emanuele Marzetti","doi":"10.1016/j.tjfa.2025.100119","DOIUrl":"10.1016/j.tjfa.2025.100119","url":null,"abstract":"","PeriodicalId":51629,"journal":{"name":"Journal of Frailty & Aging","volume":"15 1","pages":"100119"},"PeriodicalIF":3.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12757615/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145752281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A multicomponent intervention consisting of exercise, proteins and omega-3 supplementation to improve sarcopenia in community-dwelling older adults: Lessons learned from a 5-armed randomized controlled feasibility trial.","authors":"Nadjia Amini, Jolan Dupont, Laurence Lapauw, Laura Vercauteren, Lisa Peeters, Lenore Dedeyne, Sabine Verschueren, Jos Tournoy, Evelien Gielen","doi":"10.1016/j.tjfa.2025.100129","DOIUrl":"10.1016/j.tjfa.2025.100129","url":null,"abstract":"<p><strong>Background: </strong>Anabolic interventions, including physical exercise, proteins and omega-3 polyunsaturated fatty acids (PUFAs) supplementation, have shown effectiveness in improving sarcopenia outcomes. However, data on their combined effects in older adults with sarcopenia remain limited.</p><p><strong>Objectives: </strong>To assess feasibility, acceptability, and preliminary effects of a multicomponent intervention combining individualized home-based exercise, proteins, and/or omega-3 supplementation.</p><p><strong>Design: </strong>Parallel five-armed randomized assessor-blinded controlled feasibility trial with triple-blinded supplementation.</p><p><strong>Participants and setting: </strong>Community-dwelling older adults (≥65 years) diagnosed with sarcopenia (EWGSOP2-criteria) from the Exercise and Nutrition for Healthy Ageing (ENHANce) study. The ENHANce study was registered on ClinicalTrials.gov (NCT03649698).</p><p><strong>Intervention: </strong>Participants were randomized into 5 groups: 1) Exercise, 2) Proteins, 3) Exercise+Protein, 4) Exercise+Protein+Omega-3, and 5) Control group.</p><p><strong>Measurements: </strong>Feasibility was assessed via eligibility, recruitment, retention, and data completion rates. Acceptability was evaluated through participants' feedback, adherence, and safety. Effects were measured by changes in sarcopenia outcomes after 12 weeks.</p><p><strong>Results: </strong>Fifty-eight participants (76.2±6.6years,♀:65.5%) were included (Exercise,n=9;Protein,n=12; Exercise+Protein,n=13;Exercise+Protein+Omega-3;n=12;Control,n=12). Feasibility was low, with a recruitment rate of 2%. Acceptability was moderate, with most participants completing the planned assessments and reporting positive experiences such as feeling stronger and more aware of the importance of physical activity and nutrition. However, many found the study procedures demanding, and many experienced difficulties with the protein supplements. Adherence varied widely across interventions. Safety was high, with no significant adverse effects reported. The interventions showed potential to improve chair stand test (CST), Short Physical Performance Battery (SPPB), muscle mass and quadriceps strength.</p><p><strong>Conclusion: </strong>A multicomponent intervention to treat sarcopenia showed low feasibility, moderate acceptability, and high safety. Preliminary efficacy results showed that exercise with protein supplementation may improve physical function. Adding omega-3 PUFA might offer further benefits for muscle strength and mass, but should be confirmed in larger studies. The insights and the practical challenges in the ENHANce study inform future sarcopenia intervention designs.</p>","PeriodicalId":51629,"journal":{"name":"Journal of Frailty & Aging","volume":"15 1","pages":"100129"},"PeriodicalIF":3.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12887399/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146115002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between the Frailty Index and psoriasis: a cross-sectional study of the U.S. NHANES 2003-2006.","authors":"Xiaodan Wang, Wenjia Weng, Zhenzhen Yan, Ming Zhang, Juan Li, Bingbing Song, Yanqing Gao","doi":"10.1016/j.tjfa.2025.100102","DOIUrl":"10.1016/j.tjfa.2025.100102","url":null,"abstract":"<p><strong>Background: </strong>Psoriasis is a chronic inflammatory skin disease often accompanied by various comorbidities, but its relationship with frailty remains understudied. The Frailty Index (FI), calculated based on 49 health deficits across multiple systems (e.g., cognition, function, comorbidities, laboratory values) was used as a continuous measure.</p><p><strong>Objectives: </strong>We investigated the association between psoriasis and the Frailty Index (FI), providing evidence to support the implementation of frailty screening and potential interventions in patients with psoriasis.</p><p><strong>Design and setting: </strong>This cross-sectional study used data from the 2003-2006 U.S. National Health and Nutrition Examination Survey (NHANES) including 6532 participants.</p><p><strong>Measurements: </strong>We analyzed the psoriasis-FI relationship using weighted nested regression, supplemented by subgroup analyses and restricted cubic spline regression to test for nonlinear relationships.</p><p><strong>Results: </strong>The FI was significantly higher in patients with psoriasis (n = 162) than in those without (n = 6370; P < 0.001). Weighted nested regression analysis showed a significant positive association between FI and psoriasis (OR 2.22; 95% CI 1.14-4.35; P = 0.02). The association was stronger for male patients, those with normal body mass index, hypertension, and diabetes. Nonlinear relationships were observed between FI and psoriasis.</p><p><strong>Conclusions: </strong>The present study validates the association between psoriasis and frailty using a nationally representative sample and provides empirical support for integrating frailty evaluations into psoriasis care. Our findings are consistent with the hypothesis that chronic inflammatory pathways may underlie the association between psoriasis and frailty.</p>","PeriodicalId":51629,"journal":{"name":"Journal of Frailty & Aging","volume":"15 1","pages":"100102"},"PeriodicalIF":3.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12757621/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145752284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploratory functional and quality of life outcomes with daily consumption of the ketone ester bis-octanoyl (R)-1,3-butanediol in healthy older adults: a randomized, parallel arm, double-blind, placebo-controlled study.","authors":"Brianna J Stubbs, Elizabeth B Stephens, Tyler Mansfield, Chatura Senadheera, Stephanie Roa Diaz, Sawyer Peralta, Laura Alexander, Wendie Silverman-Martin, Jamie Kurtzig, B Ashen Fernando, Thelma Y Garcia, Michi Yukawa, Jennifer Morris, James T Yurkovich, Anne B Newman, James B Johnson, Peggy M Cawthon, John C Newman","doi":"10.1016/j.tjfa.2025.100106","DOIUrl":"10.1016/j.tjfa.2025.100106","url":null,"abstract":"<p><strong>Background: </strong>Ketone bodies are metabolites produced during fasting or on a ketogenic diet that have pleiotropic effects on the inflammatory and metabolic aging pathways underpinning frailty in vivo models. Ketone esters (KEs) are compounds that induce hyperketonemia without dietary changes and that may impact physical and cognitive function in young adults. The functional effects of KEs have not been studied in older adults.</p><p><strong>Objectives: </strong>Our long-term goal is to examine if KEs modulate aging biology mechanisms and clinical outcomes relevant to frailty in older adults. Here, we report the exploratory functional and quality-of-life outcome measures collected during a 12-week safety and tolerability study of KE (NCT05585762).</p><p><strong>Design: </strong>Randomized, placebo-controlled, double-blinded, parallel-group, pilot trial of 12-weeks of daily KE ingestion.</p><p><strong>Setting: </strong>The Clinical Research Unit at the Buck Institute for Research on Aging, California.</p><p><strong>Participants: </strong>Community-dwelling older adults (≥65 years), independent in activities of daily living, with no unstable acute medical conditions (n = 30).</p><p><strong>Intervention: </strong>Participants were randomly allocated (1:1) to consume 25 g daily of either KE (bis-octanoyl (R)-1,3-butanediol) or a taste, appearance, and calorie-matched placebo (PLA) containing canola oil.</p><p><strong>Measurements: </strong>Longitudinal change in physical function, cognitive function and quality of life were assessed as exploratory outcomes in n = 23 completers (n = 11 PLA, n = 12 KE). A composite functional outcome intended for interventional frailty trials was derived and calculated. Heart rate and activity was measured throughout the study using digital wearables.</p><p><strong>Results: </strong>There were no statistically significant longitudinal differences between groups in exploratory functional, activity-based or quality of life outcomes.</p><p><strong>Conclusion: </strong>Daily ingestion of 25 g of KE did not affect exploratory functional or quality-of-life end points in this pilot cohort of healthy older adults. Future work will address these endpoints as primary and secondary outcomes in a larger trial of pre-frail older adults.</p>","PeriodicalId":51629,"journal":{"name":"Journal of Frailty & Aging","volume":"14 6","pages":"100106"},"PeriodicalIF":3.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12790065/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145642574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A two-stage analysis of social media use patterns, psychosocial well-being, and frailty in an aging Japan.","authors":"Yuki Nakada, Yuna Seo","doi":"10.1016/j.tjfa.2025.100091","DOIUrl":"10.1016/j.tjfa.2025.100091","url":null,"abstract":"<p><strong>Background: </strong>In Japan's super-aged society, frailty prevention is a critical public health issue. While social media use is increasing among older adults, its impact on well-being is complex and not fully understood beyond a simple active-passive dichotomy. This study aims to explore the relationship between specific social media usage patterns, users' psychosocial backgrounds, and frailty risk.</p><p><strong>Methods: </strong>We conducted a cross-sectional online survey of 950 community-dwelling older adults in Japan. Frailty was assessed using the Kihon Checklist. A two-stage analysis was performed: 1) K-means cluster analysis was used to classify participants based on eight SOCIAL MEDIA use behavior variables, followed by a Kruskal-Wallis test to compare psychosocial characteristics across clusters; 2) Ordinal logistic regression analysis was used to identify specific behaviors associated with frailty after adjusting for covariates.</p><p><strong>Results: </strong>Three distinct user clusters were identified: \"Balanced, reality-oriented communicators\" (n = 333), \"Low-engagement, passive users\" (n = 419), and \"Active, multi-purpose users\" (n = 198). The \"Low-engagement\" group reported the highest levels of loneliness and unhappiness, despite high real-world social participation. Regression analysis revealed that the specific behavior of \"using social media to keep a record of my own activities\" (self-documentation) was independently associated with an increased risk of frailty (β = 0.105, p < .05). Conversely, high exercise self-efficacy (p < .001), sleep satisfaction (p < .01), and satisfaction with face-to-face communication (p < .001) were protective factors.</p><p><strong>Conclusion: </strong>Social media usage patterns reflect underlying psychosocial states, but are not direct predictors of frailty. The motivation-driven behavior of self-documentation, rather than general activity, is a risk factor. These findings suggest that interventions should focus on the quality and function of social media use, promoting digital literacy that enhances well-being in older adults.</p>","PeriodicalId":51629,"journal":{"name":"Journal of Frailty & Aging","volume":"14 6","pages":"100091"},"PeriodicalIF":3.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12516035/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145214377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"Balance T\" device improves balance confidence and performance in repeated measures study.","authors":"Courtney Walker, June Nicholas, Crystal Szczesny, Jeremy Walston, Yuri Agrawal, Michael C Schubert","doi":"10.1016/j.tjfa.2025.100113","DOIUrl":"10.1016/j.tjfa.2025.100113","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this research is to determine if balance can be improved in older adults from exercising at home using a novel piece of exercise equipment called the \"Balance T\".</p><p><strong>Method: </strong>Fifty older adults (77.9 ± 6.7 years old) participated in a four-week home exercise, open-label clinical pilot study investigating ability to improve balance using the Balance T device. Pre- and post-intervention assessments included the Activities-specific Balance Confidence (ABC) Scale, Short Physical Performance Battery (SPPB), Timed Up and Go (TUG), Clinical Test of the Sensory Interaction on Balance (CTSIB), Balance T Change Score (BTCS), and a user-opinion survey. Statistical analyses comprised parametric and non-parametric tests for pre-post exercise comparisons as well as evaluated balance differences across frailty status using established frailty-defining criteria.</p><p><strong>Results: </strong>Frail participants at-risk for falls exhibited greater improvement in balance confidence compared to robust participants, with a mean change of 5.28 ± 12.9 (p < 0.001). In addition, each performance variable of balance showed clinically significant and meaningful changes after completing the Balance T exercise program. Participants reported the Balance T device as easy and safe to use with benefits gained at improving their balance.</p><p><strong>Conclusion: </strong>The Balance T device proved feasible for home use, showing preliminary evidence of improved balance performance and confidence, particularly among frail adults.</p>","PeriodicalId":51629,"journal":{"name":"Journal of Frailty & Aging","volume":"14 6","pages":"100113"},"PeriodicalIF":3.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12704060/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145642514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The interrelationship of frailty, multimorbidity and disability in Parkinson's disease: PRIME-UK cross-sectional study.","authors":"Emma Tenison, Yoav Ben-Shlomo, Anahita Nodehi, Emily J Henderson","doi":"10.1016/j.tjfa.2025.100073","DOIUrl":"10.1016/j.tjfa.2025.100073","url":null,"abstract":"<p><strong>Background: </strong>The prevalence of Parkinson's disease rises with age and so patients may also be living with multimorbidity, two or more long-term conditions, and frailty, a loss of physiological reserve. However, these individuals are typically under-represented in clinical research. The aim was to describe the prevalence and interrelationship of frailty, multimorbidity, disability, sarcopenia and polypharmacy in a representative sample of people with parkinsonism recruited to the PRIME-UK cross-sectional study.</p><p><strong>Methods: </strong>In this single-centre cross-sectional study of people with parkinsonism, we supported the inclusion of typically under-represented groups including those with impaired capacity to consent to the research. Participants, or their representative, completed questionnaires including self-reported comorbidities, medications, a sarcopenia screening tool and measures of frailty and disability. Venn diagrams were used to show the overlap between these domains and a hierarchical cluster analysis was performed to explore clustering.</p><p><strong>Results: </strong>Only 78 (16.8 %) were categorised as neither frail nor multimorbid nor disabled. Almost all patients living with frailty were additionally living with disability and/or multimorbidity. It was uncommon to have multimorbidity and frailty without disability. Only 6 (1.3 %) had frailty without probable sarcopenia. Individuals clustered into three groups based on co-occurrence of some or all of these five domains.</p><p><strong>Conclusions: </strong>Amongst a representative sample of people with parkinsonism, there was a high frequency and co-occurrence of pre-frailty/frailty, sarcopenia, multimorbidity, polypharmacy and disability. This has implications for the structuring of health services for people with parkinsonism. There may also be opportunities to intervene to stop or slow the trajectory towards disability.</p>","PeriodicalId":51629,"journal":{"name":"Journal of Frailty & Aging","volume":"14 6","pages":"100073"},"PeriodicalIF":3.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12528879/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145228665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frail2Fit study: it was feasible and acceptable for volunteers to deliver a remote health intervention to older adults with frailty.","authors":"S J Meredith, L Holt, J Varkonyi-Sepp, A Bates, K A Mackintosh, M A McNarry, S Jack, J Murphy, Mpw Grocott, Ser Lim","doi":"10.1016/j.tjfa.2025.100092","DOIUrl":"10.1016/j.tjfa.2025.100092","url":null,"abstract":"<p><strong>Background: </strong>Physical activity (PA) and good nutrition are key to maintaining independence and reversing frailty among older adults.</p><p><strong>Objective: </strong>To evaluate the feasibility and acceptability of training volunteers to deliver a remote multimodal intervention to older people with frailty after hospital discharge.</p><p><strong>Design: </strong>Quasi-experimental mixed-methods feasibility study.</p><p><strong>Setting, and participants: </strong>Twenty-seven older adults (mean age 80 years, 15 female) with frailty (Clinical Frailty Status ≥5) were enrolled from a National Health Service South England hospital, UK.</p><p><strong>Intervention: </strong>Volunteers were trained to deliver a 3-month intervention, comprising exercise, behaviour change, and nutrition guidance in a group, or one-to-one, using telephone or online platforms.</p><p><strong>Measurements: </strong>Feasibility was assessed by determining the number of volunteers recruited, trained, and retained; participant recruitment; and intervention adherence. Interviews were conducted with 16 older adults, 1 carer, and 5 volunteers to explore intervention acceptability, and were analysed using reflexive thematic analysis. Secondary health outcomes, such as physical activity and appetite, were compared at baseline, post-intervention, and follow-up (3-months).</p><p><strong>Results: </strong>The intervention was safe and acceptable to volunteers, and older adults with frailty. Five volunteers (mean age 16 years, 3 female) completed training, and 60 % (n = 3) were retained. Seventeen participants completed the intervention (8 online; 9 telephone). Participants attended 75 % (IQR 38-92) online sessions, and 80 % (IQR 68.5-94.5) telephone support. Volunteers provided emotional support to older people with frailty and encouraged health behaviour change. Older people learnt from each other's shared experiences in the online group, and telephone calls provided them with reassurance and monitoring. Key components to success were volunteers received comprehensive training and support from a health practitioner, while key barriers were that participants lacked social support and experienced exercise discomfort.</p><p><strong>Conclusion: </strong>With appropriate training and support, volunteers can safely deliver a remote multimodal intervention for older adults with frailty following discharge from hospital.</p>","PeriodicalId":51629,"journal":{"name":"Journal of Frailty & Aging","volume":"14 6","pages":"100092"},"PeriodicalIF":3.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12519248/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145228696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}