Journal of Frailty & Aging最新文献

{"title":"Frailty indices based on routinely collected data: a scoping review.","authors":"Schenelle Dayna Dlima, Danielle Harris, Abodunrin Quadri Aminu, Alex Hall, Chris Todd, Emma Rlc Vardy","doi":"10.1016/j.tjfa.2025.100047","DOIUrl":"https://doi.org/10.1016/j.tjfa.2025.100047","url":null,"abstract":"<p><p>A frailty index (FI) is a frailty assessment tool calculated as the proportion of the number of health-related deficits an individual has to the total number of variables in the index. Routinely collected clinical and administrative data can be used as sources of deficits to automatically calculate FIs. This scoping review aimed to evaluate the current research landscape on routine data-based FIs. We searched seven databases to find literature published in 2013-2023. Main inclusion criteria were original research articles on FIs constructed from routine data, with deficits in at least two of the following categories: \"symptoms/signs\", \"laboratory values\", \"diseases\", \"disabilities\", and \"others\". From 7526 publications screened, 218 were included. Studies were primarily from North America (47.7 %), conducted in the community (35.3 %), and used routine data-based FIs for risk stratification (51.4 %). FIs were calculated using various routine data sources; however, most were initially developed and validated using hospital records. We noted geographical differences in study settings and routine data sources. We identified 611 unique deficits comprising these FIs. Most were either \"diseases\" (34.4 %) or \"symptoms/signs\" (32.1 %). Routine data-based FIs are feasible and valid risk stratification tools, but research is confined to high-income countries, their routine adoption is slow, and deficits comprising these FIs emphasise a reactive and overtly medical approach in addressing frailty. Future directions include exploring the feasibility and applicability of using routine databases for frailty assessment in lower- and middle-income countries, and leveraging non-clinical routine data through data linkages to proactively identify and manage frailty.</p>","PeriodicalId":51629,"journal":{"name":"Journal of Frailty & Aging","volume":"14 3","pages":"100047"},"PeriodicalIF":3.3,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144028107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sarcopenia is associated with lower quality of life scores among community-dwelling older Filipinos: Findings from a cross-sectional study.","authors":"Robby Carlo Tan, Kyler Kenn Castilla, Michael Serafico, Marco Mensink, Lisette de Groot","doi":"10.1016/j.tjfa.2025.100044","DOIUrl":"https://doi.org/10.1016/j.tjfa.2025.100044","url":null,"abstract":"<p><strong>Background and objectives: </strong>Sarcopenia, characterized by a progressive decline in muscle mass and strength, is a significant concern among older individuals, impacting their functionality and overall quality of life (QOL). The relationship between sarcopenia and QOL among Filipino older adults remains underexplored. Thus, the study aims to determine the prevalence of sarcopenia and its association with the QOL of community-dwelling older adults in selected Philippine cities.</p><p><strong>Design: </strong>This cross-sectional study used convenience sampling in the selection of the cities. Participants were randomly selected from the list provided by each local city government.</p><p><strong>Setting and participants: </strong>536 apparently healthy community-dwelling Filipino older adults from three major islands in the Philippines.</p><p><strong>Methods: </strong>Sarcopenia was determined using the 2019 Asian Working Group for Sarcopenia criteria which is the presence of low muscle mass, plus low muscle strength, and/or low physical performance. Quality of life was assessed using the culturally-validated WHO-QOL short form questionnaire. Mixed Model logistic regression adjusted for covariates was performed to study the association of sarcopenia indicators to quality of life.</p><p><strong>Results: </strong>24.3 % of older Filipinos were found to have sarcopenia. Sarcopenic community-dwelling older adults had significantly decreased odds of attaining higher score in the physical domain (OR 0.63; 0.40-0.98), psychological domain (OR 0.55; CI 0.35-0.84), and overall quality of life (OR 0.57; CI 0.37-0.89) than the non-sarcopenic group.</p><p><strong>Conclusion: </strong>One in four community-dwelling Filipino older adults met the sarcopenia criteria. Sarcopenia is associated with decreased QOL scores, particularly in the physical health and psychological health domains. Sarcopenia needs to be considered in the context of public health to come up with targeted nutrition and health interventions for improved QOL.</p>","PeriodicalId":51629,"journal":{"name":"Journal of Frailty & Aging","volume":"14 3","pages":"100044"},"PeriodicalIF":3.3,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144005320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to \"Implementing Occupational Therapy into an Acute Geriatric Ward: Effects on Patients' Functional Status at Discharge\" [J Frailty Aging 13 (2024) 307-12].","authors":"C Sidoli, C Okoye, A Staglianò, A Zambon, C Pozzi, M C Ferrara, G Bellelli","doi":"10.1016/j.tjfa.2025.100049","DOIUrl":"https://doi.org/10.1016/j.tjfa.2025.100049","url":null,"abstract":"","PeriodicalId":51629,"journal":{"name":"Journal of Frailty & Aging","volume":"14 3","pages":"100049"},"PeriodicalIF":3.3,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Framework for a short muscle function battery using electronic handgrip dynamometry and accelerometry in older adults.","authors":"Ryan McGrath, Grant R Tomkinson, Sarah Andrew, Joshua Batesole, Chloe Carling, Bryan K Christensen, Samantha FitzSimmons, Halli Heimbuch, Tyler Hoang, Donald Jurivich, Jacob Kieser, Kelly Knoll, Peyton Lahr, Matthew Langford, Michaela Mastrud, Megan Orr, Yeong Rhee, Kyle J Hackney","doi":"10.1016/j.tjfa.2025.100045","DOIUrl":"https://doi.org/10.1016/j.tjfa.2025.100045","url":null,"abstract":"<p><strong>Background: </strong>Electronic handgrip dynamometry and accelerometry enables novel opportunities to collect additional attributes of muscle function beyond just maximal strength, but some muscle function attributes may already be related, which may warrant discerning these attributes into a short muscle function battery (SMFB).</p><p><strong>Objectives: </strong>We sought to determine the multivariate relationships between maximal strength, asymmetry, submaximal control, rate of force development, bimanual coordination, fatigability, and contractile steadiness in older adults.</p><p><strong>Design: </strong>A cross-sectional design was used for this investigation.</p><p><strong>Setting: </strong>Laboratory.</p><p><strong>Participants: </strong>The analytic sample included 121 generally healthy older adults aged 70.7 ± 4.7 years.</p><p><strong>Measurements: </strong>Electronic handgrip dynamometry and accelerometry measured strength, asymmetry, submaximal control, rate of force development, bimanual coordination, fatigability, and contractile steadiness. The handgrip variables were standardized before they were included in a factor analysis. Factors with eigenvalues >1.0 were kept. Items within a factor with a loading |>0.30| were similarly retained.</p><p><strong>Results: </strong>There were 3 factors retained with eigenvalues of 1.88, 1.56, and 1.10. The first factor (functional strength), which explained 39.9 % of the variance, included strength, submaximal control, and rate of force development. Factor 2 (lateral function), which explained 35.8 % of the variance, included asymmetry and bimanual coordination. The third factor (muscle endurance), which explained 24.3 % of the variance, included fatigability and contractile steadiness.</p><p><strong>Conclusions: </strong>Our findings suggest the surfacing of themes in the additional muscle function measures, thereby providing framework for a SMFB. More research is needed for electronic handgrip dynamometry and accelerometry derived muscle function on health before consideration of implementation in clinical practice.</p>","PeriodicalId":51629,"journal":{"name":"Journal of Frailty & Aging","volume":"14 3","pages":"100045"},"PeriodicalIF":3.3,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reflection points on how frailty concepts have changed clinical practice.","authors":"Cornel Christian Sieber","doi":"10.1016/j.tjfa.2025.100046","DOIUrl":"https://doi.org/10.1016/j.tjfa.2025.100046","url":null,"abstract":"","PeriodicalId":51629,"journal":{"name":"Journal of Frailty & Aging","volume":"14 3","pages":"100046"},"PeriodicalIF":3.3,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144008010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maximising inclusivity in care home research: Lessons learned from the AFRI-c randomised controlled trial.","authors":"Laurel Campbell-Smith, Sophie Rees, Jane Sprackman, Karen Sargent, Alastair D Hay, Rachel Cm Brierley","doi":"10.1016/j.tjfa.2025.100038","DOIUrl":"https://doi.org/10.1016/j.tjfa.2025.100038","url":null,"abstract":"<p><p>Ethical and procedural requirements make research in care homes challenging. With people living longer globally, it is essential that older people are included in research, including within the care home setting. We conducted a randomised controlled trial (AFRI-c) in 91 care homes across England, aiming to make the study available to every eligible resident. Facilitators included flexible models for receiving consent; commitment from care home staff, residents and families; tailored and specific training for care home staff; and support from national research infrastructure to engage care homes in research. To facilitate inclusive care home research, we recommend consulting with care homes about their research priorities; continuing investment in national research infrastructure for care homes; using advance directives for research planning for care home residents; embedding research nurses in care home environments; and more guidance for researchers and ethics committees on applying legal frameworks regarding capacity to research settings.</p>","PeriodicalId":51629,"journal":{"name":"Journal of Frailty & Aging","volume":"14 3","pages":"100038"},"PeriodicalIF":3.3,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of objective and subjective socioeconomic status with intrinsic capacity deficits among community-dwelling middle-aged and older adults in China: A cross-sectional study.","authors":"Fangqin Tan, Xiaoxia Wei, Ji Zhang, Yihao Zhao, Yue Zhang, Haiying Gong, Jean-Pierre Michel, Enying Gong, Ruitai Shao","doi":"10.1016/j.tjfa.2025.100036","DOIUrl":"10.1016/j.tjfa.2025.100036","url":null,"abstract":"<p><strong>Background: </strong>Intrinsic capacity (IC), representing an individual's full range of physical and mental abilities, is influenced by objective socioeconomic status (SES); however, the impact of subjective SES remains unclear.</p><p><strong>Objectives: </strong>This study aims to assess IC and investigate the relationship between SES and IC deficits, with a particular focus on the role of subjective SES.</p><p><strong>Design: </strong>Cross-sectional study SETTING: 45 communities in two provinces in China PARTICIPANTS: Community-dwelling middle-aged and older adults aged 50 and above MEASUREMENTS: IC was assessed following the Integrated Care for Older People guideline. SES was measured through objective SES (education and occupation) and subjective SES (measured by MacArthur Scale). Ordinal logistic regression models were performed to estimate the association between SES and IC.</p><p><strong>Results: </strong>Among 3,058 participants (61.3 ± 8.05 years, 54.8 % women), 2,333 (76.3 %) showed deficits in at least one IC subdomain, particularly sensory (63.5 %), vitality (25.8 %) and cognition (18.4 %). A dose-response association was observed between SES and IC deficits. Individuals with high subjective SES (OR: 0.72, 0.60-0.87), high education (OR: 0.54, 0.38-0.75), and high occupation (OR: 0.64 0.50-0.81) exhibited lower IC deficits risk compared with counterparts. Individuals with high education and middle subjective SES or high occupation and middle subjective SES had 67 % (OR: 0.33, 0.18-0.60) and 49 % (OR: 0.51, 0.35-0.74) lower risk than those with low SES.</p><p><strong>Conclusions: </strong>These findings suggest that individuals with low SES may be more vulnerable to IC deficits. Addressing social inequalities in the early assessment of IC is crucial for reducing health disparities and promoting healthy ageing.</p>","PeriodicalId":51629,"journal":{"name":"Journal of Frailty & Aging","volume":"14 2","pages":"100036"},"PeriodicalIF":3.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The development of frailty trajectories in world trade center general responders and the association with World Trade Center Exposure.","authors":"Hannah M Thompson, Katherine A Ornstein, Elena Colicino, Nicolo Foppa Pedretti, Ghalib Bello, Ahmad Sabra, Erin Thanik, Roberto G Lucchini, Michael Crane, Susan L Teitelbaum, William W Hung, Fred Ko","doi":"10.1016/j.tjfa.2025.100027","DOIUrl":"10.1016/j.tjfa.2025.100027","url":null,"abstract":"<p><strong>Background: </strong>As the World Trade Center (WTC) General Responder Cohort ages, it is imperative to study their aging process and identify factors that can be targeted for interventions.</p><p><strong>Objectives: </strong>Our goal was to utilize a previously developed WTC Clinical Frailty Index (CFI) to identify distinct frailty trajectories and associated factors in this cohort.</p><p><strong>Design: </strong>A latent class mixed model evaluated frailty trajectories using WTC CFIs. Multinomial regression models were used to assess associations between frailty trajectory and sociodemographic and WTC characteristics.</p><p><strong>Setting: </strong>We utilized data collected during routine WTC monitoring visits from 2004 until 2021.</p><p><strong>Participants: </strong>The participants were WTC general responders.</p><p><strong>Measurements: </strong>Relative risk ratios (RRR) assessed associations with a 95 % confidence interval (CI).</p><p><strong>Results: </strong>Three distinct linear frailty trajectories were identified: high CFI (indicating higher frailty), low CFI, and progressively increasing CFI. Compared with the low CFI group, females were more likely to be in the high CFI and progressively increasing CFI groups (RRR 1.66, 95 %CI 1.46, 1.90; RRR 1.32, 95 %CI 1.15, 1.53, respectively). Education beyond high school and elevated income were protective against high CFI and progressively increasing CFI groups. Individuals that self-identified as Hispanic had an elevated RRR for the high CFI group (RRR 1.17, 95 %CI 1.04, 1.31). Occupation on 9/11, such as construction and maintenance and repair, as well as high/very high WTC exposure were significantly associated with both the high CFI and progressively increasing CFI groups.</p><p><strong>Conclusions: </strong>Several sociodemographic and WTC variables were associated with more hazardous frailty trajectories in WTC general responders. This work is beneficial to informing and directing future interventions for those at higher-risk for more hazardous frailty progression.</p>","PeriodicalId":51629,"journal":{"name":"Journal of Frailty & Aging","volume":"14 2","pages":"100027"},"PeriodicalIF":3.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12004615/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143582404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Community-based physical activity and nutrition interventions in low-income and/or rural older adults: A scoping review.","authors":"Elizabeth Bernard, Nash Brewer, Jeanette C Prorok, Perry Kim, John Muscedere","doi":"10.1016/j.tjfa.2025.100034","DOIUrl":"10.1016/j.tjfa.2025.100034","url":null,"abstract":"<p><p>The objective of this review was to identify evidence-based, community-based physical activity (PA) and nutrition-based programs aimed at facilitating health behaviour change among low-income older adults and/or those living in rural/remote areas. This review followed the scoping review methodology proposed by Arksey & O'Malley. The Michie behaviour change wheel was used to categorize intervention types. Of the 2954 retrieved citations, 25 articles met the inclusion criteria. All study interventions demonstrated positive outcomes, including improvements in fruit and vegetable consumption, PA levels, physical function and nutrition knowledge. Study findings highlight that PA and nutrition-based interventions can be effective to facilitate behavior change in low-income and/or rural older adults. Limited research exists looking specifically at older adults living in rural communities, with only two of the 25 included articles including rural study populations.</p>","PeriodicalId":51629,"journal":{"name":"Journal of Frailty & Aging","volume":"14 2","pages":"100034"},"PeriodicalIF":3.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frailty and associated healthcare expenditures among patients undergoing total hip and knee arthroplasty.","authors":"Donna Ron, Alton B Daley, Marcus P Coe, Michael D Herrick, Robert H Roth, Alexander T Abess, Pablo Martinez-Camblor, Stacie G Deiner, Myles D Boone","doi":"10.1016/j.tjfa.2025.100030","DOIUrl":"10.1016/j.tjfa.2025.100030","url":null,"abstract":"<p><strong>Background: </strong>Major joint surgery is one of the largest components of Medicare spending in the US and the most frequent major procedure performed in older adults. Increasing age is associated with increasing prevalence of frailty, but the influence of frailty on healthcare expenditures following arthroplasty has yet to be adequately explored.</p><p><strong>Objective: </strong>To explore the association between frailty and healthcare expenditures in the year following total hip and knee arthroplasties.</p><p><strong>Design: </strong>Retrospective cohort study SETTING: United States population PARTICIPANTS: Medicare beneficiaries 65 and older undergoing total knee or hip arthroplasty (n = 1,152,872) from 2017 through 2018.</p><p><strong>Measurements: </strong>Claims-based frailty index (exposure), total 1-year Medicare expenditures broken down by category (primary outcome), in-hospital complications, length of stay, discharge destination, readmission and mortality (secondary outcomes).</p><p><strong>Results: </strong>Among 435,496 patients who underwent hip (37.8 %) and 717,376 patients who underwent knee arthroplasty (62.2 %), the mean age was 73.7 years and 19.2 % were classified as frail. Median total expenditures in US dollars at one year were higher in those with frailty ($247,503; IQR [$169,400-$391,176]) relative to the prefrail ($179,379 [$127,396-$265,039]) and robust ($130,314 [$85,438-$199,605]) groups. Total expenditures included the index surgical admission, rehospitalization, skilled nursing care, and outpatient care, all of which were higher with increasing frailty. However, the surgical procedure accounted for less than a third of the total 1-year healthcare costs and was the category with the lowest degree of variation between patients. Frailty was also associated with longer lengths of stay, higher risks of complications, readmission, and mortality and lower likelihood of being discharged home after the procedure.</p><p><strong>Conclusions: </strong>Among older adults undergoing total hip and knee arthroplasty, frailty is associated with higher healthcare expenditures, predominantly driven by longitudinal care during the year following the procedure. More research is needed to test interventions to improve outcomes and reduce cost in this high-risk population.</p>","PeriodicalId":51629,"journal":{"name":"Journal of Frailty & Aging","volume":"14 2","pages":"100030"},"PeriodicalIF":3.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}