Journal of Ultrasound最新文献

{"title":"Antenatal unilateral upper limb acromesomelic dysplasia.","authors":"Shruti Thakur, Charu Smita Thakur, Anupam Jhobta, Vikrant Negi","doi":"10.1007/s40477-024-00954-0","DOIUrl":"10.1007/s40477-024-00954-0","url":null,"abstract":"<p><p>Acromesomelic dysplasia (AMD) is an umbrella term given to a heterogeneous group of progressive skeletal disorders characterized by short limbed dwarfism associated with disproportionate shortening of middle and distal segments of the upper as well as lower limbs. Although specific skeletal anomalies are difficult to diagnose antenatally, but because of their antenatal and postnatal implications and a possibility of reoccurrence in following pregnancies, such skeletal anomalies need to be actively addressed. A combination of radiologic, pathologic, genetic and molecular investigation prenatally as well as postnatally is required to classify a specific congenital skeletal dysplasia. Once the genetic make-up of fetal skeletal dysplasia is deciphered, a meaningful genetic counselling could be offered for future pregnancies of affected families. We describe a case of primigravida diagnosed with fetal unilateral upper limb AMD on antenatal ultrasound done at early second trimester. The radius and ulna of left upper limb were abnormally short (less than 5th centile of the mean for that gestational age). The left hand was also hypoplastic. Rest of the sonographic anomaly scan was normal. To the best of our knowledge, AMD limited to unilateral upper limb diagnosed antenatally as an isolated finding is not described in the medical literature so far.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":"225-228"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13000051/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142300503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating morphology, vascularity, and elasticity: diagnostic role of multiparametric quantitative ultrasound in breast lesions.","authors":"Paridhi Sabharwal, Narinder Kaur, Ravinder Kaur, Rajesh Bansiwal, Ranjeev Bhagat","doi":"10.1007/s40477-026-01116-0","DOIUrl":"10.1007/s40477-026-01116-0","url":null,"abstract":"<p><strong>Objectives: </strong>To determine the incremental diagnostic value of multiparametric quantitative ultrasound-integrating B-mode, Color Doppler, Strain, and Shear Wave Elastography (SWE)-in differentiating benign and malignant breast lesions, using histopathology/FNAC as the gold standard.</p><p><strong>Methods: </strong>Seventy patients with 87 breast lesions underwent comprehensive ultrasound by a resident and a consultant radiologist (> 20 years' experience) with consensus reporting. Each lesion was evaluated using B-mode (BI-RADS), Color Doppler (vascularity, resistive and pulsatility indices), Strain elastography (strain ratio), and SWE (stiffness in kPa). Pathological correlation was available for all lesions. Diagnostic performance of individual and combined parameters was assessed using sensitivity, specificity, PPV, NPV, accuracy, and ROC analysis. Multivariate logistic regression evaluated incremental value of multiparametric combinations.</p><p><strong>Results: </strong>B-mode had the highest sensitivity (88.37%) and accuracy (82.76%), Color Doppler the highest specificity (95.45%) but low sensitivity (55.81%), while Strain and SWE showed balanced performance, with SWE achieving the highest accuracy (85.06%) and AUC (0.85). Adding Color Doppler or Strain to B-mode provided no additional benefit. Incorporating SWE improved specificity (88.64%) and accuracy (85.06%). B-mode + Strain + Color Doppler achieved 83.91% accuracy, whereas B-mode + SWE + Color Doppler provided the highest overall performance (sensitivity 86.05%, specificity 86.36%, accuracy 86.21%, AUC 0.86). The four-parameter model (B-mode + Color Doppler + Strain + SWE) showed 83.72% sensitivity, 86.36% specificity, AUC 0.85, and 85.06% accuracy, performing comparably but marginally inferior to the best triple combination (B-mode + Color Doppler + SWE), likely due to redundancy and threshold effects, indicating that adding Strain did not improve performance.</p><p><strong>Conclusion: </strong>Multiparametric ultrasound enhances lesion differentiation. B-mode ensures sensitivity, Color Doppler confirms benign vascular patterns, and SWE provides quantitative stiffness assessment. Combining morphology, vascularity, and stiffness-particularly B-mode + SWE + Color Doppler-yields the highest diagnostic accuracy.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":"155-179"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13000076/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146144538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in abdominal muscles' thickness from rest to pelvic floor isolated contraction in healthy women.","authors":"Bruna Bohrer Mozzaquatro, Francesca Chaida Sonda, Fábio Juner Lanferdini, Amanda Zanella de Mello, Suzana Mallmann, Andriéli Aparecida Salbego Lançanova, Luciana Laureano Paiva, Marco Aurélio Vaz, José Geraldo Lopes Ramos","doi":"10.1007/s40477-025-01105-9","DOIUrl":"10.1007/s40477-025-01105-9","url":null,"abstract":"<p><strong>Objectives: </strong>To compare muscle thickness of rectus abdominis, internal oblique, external oblique, and transversus abdominis between rest and PFM isolated contraction.</p><p><strong>Design: </strong>Cross-sectional reliability study.</p><p><strong>Methods: </strong>Muscle thickness from rectus abdominis, internal oblique, external oblique and transversus abdominis was obtained from 27 physically active women (age: 26.41 ± 0.77 years) with ultrasound imaging at rest and during three maximum PFM contractions. Two independent analyzers, blinded to the conditions, analyzed 3 images from each muscle and condition using Image-J 1.42q software. Muscle thickness was measured three times on each image. Differences between conditions (rest and PFM contraction) were analyzed with a Student t-test. To verify the outcome measures' inter-analyzer reliability, the intraclass correlation coefficient (ICC), standard error of the measurement (SEM), and minimum detectable change (MDC) were calculated.</p><p><strong>Results: </strong>TrA showed a significant increase in muscle thickness from rest compared to PFM isolated contraction (p < 0.001; t:-4.137). However, muscle thickness was similar for the two conditions in rectus abdominis (p = 0.093; t:1.746), internal oblique (p = 0.410; t:0.838), and external oblique (p = 0.847; t:0.196). Excellent reliability was found for muscle thickness at rest (r = 0.828-1.000; p < 0.001) and during PFM contraction (r = 0.997-1.000; p = 0.001) for rectus abdominis, internal oblique, external oblique and transversus abdominis muscles. SEM and MDC values from all outcomes were low.</p><p><strong>Conclusion: </strong>PFM isolated contraction generates a significant contraction of the transversus abdominis muscle, which helps controlling intra-abdominal pressure. The excellent inter-analyzer reliability evidence that abdominal muscles' muscle thickness is reliable when obtained by different analyzers.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":"107-114"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13000012/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145991596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"B-mode and contrast-enhanced ultrasound versus magnetic resonance imaging in hepatic angiomyolipoma: a case report.","authors":"Andrea Balbinot, Sofia Maria Bakken, Nicola Venturoli, Deborah Malvi, Elisa Albertini, Maria Giulia Pirini, Antonietta D'Errico, Carla Serra","doi":"10.1007/s40477-025-01015-w","DOIUrl":"10.1007/s40477-025-01015-w","url":null,"abstract":"<p><p>Angiomyolipoma is a solid mesenchymal tumour that usually affects the kidney. Hepatic localization of angiomyolipoma (HAML) is rare and usually asymptomatic however it presents a challenging differential diagnosis. We present the case of a 45-year-old man affected by tuberous sclerosis complex type 2 (TSC2) and an hepatic lesion suspected to be hepatocellular carcinoma on magnetic resonance but whose Bmode ultrasound and contrast-enhanced ultrasound (CEUS) findings were consistent with benignity, as confirmed by histology.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":"265-269"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13000067/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144048531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cranial ultrasound as a diagnostic tool for infant meningitis in a low-or middle income setting: \"sensitivity and specificity\".","authors":"Sadia Parkar, Kiran Hilal, Zaubina Kazi, Kumail Khandwala, Mahjabeen Zehra, Nadia Mazhar, Sanam Umair, Ali Faisal Saleem","doi":"10.1007/s40477-025-01089-6","DOIUrl":"10.1007/s40477-025-01089-6","url":null,"abstract":"<p><strong>Background: </strong>Cerebrospinal fluid (CSF) analysis remains the gold standard for diagnosing meningitis but it requires technique and time. In infants, open fontanels allow ultrasound visualization, making cranial ultrasound a low-cost, point-of-care diagnostic tool for suspected meningitis. This study aimed to develop a standardized cranial ultrasound checklist, and to assess the sensitivity and specificity of cranial ultrasound as a diagnostic tool for infants with meningitis compared with the gold standard cerebrospinal fluid (CSF) analysis.</p><p><strong>Materials and methods: </strong>This diagnostic tool validation study compared cranial ultrasound with the gold standard cerebrospinal fluid (CSF) analysis for meningitis using consecutive sampling. Infants under 12 months of age with patent fontanelles presenting to the Aga Khan University Hospital with suspected meningitis were allowed to participate.</p><p><strong>Results: </strong>Overall, 79 patients with suspected meningitis were enrolled. The mean age of the patients was 52.68 ± 82.27 days, and males were predominant (68.35%). The sensitivity, specificity, PPV, NPV, and accuracy of ultrasound were 46.81%, 56.25%, 61.11%, 41.86%, and 50.63%, respectively. The significant finding was thickened echogenic sulci 25 (31.64%), followed by meningeal thickening 23 (29.11%), white matter abnormalities 14 (17.71%), brain edema 12 (15.18%), ventricular system dilatation 6 (7.59%), and elevated CSF echogenicity 7 (8.86%).</p><p><strong>Conclusion: </strong>Cranial ultrasound showed low diagnostic accuracy for infant meningitis in this study. However, it may be used as a front-line imaging modality in the initial diagnosis and monitoring of infants with acute meningitis. It holds potential as a point-of-care diagnostic tool, and its utility may be enhanced by additional scanning approaches and Doppler techniques.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":"57-64"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13000087/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145710354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tiny patient, big challenge: pancreatic heterotopia causing ileo-ileal intussusception in an infant.","authors":"Benedetta Neri, Marco Di Mitri, Ilaria Corsini, Marcello Lanari, Michelangelo Baldazzi, Laura Greco, Simone D'Antonio, Claudio Antonellini, Rocco Minelli, Eugenio Rossi, Giuseppe Paviglianiti, Marcello Napolitano, Mario Lima","doi":"10.1007/s40477-025-01006-x","DOIUrl":"10.1007/s40477-025-01006-x","url":null,"abstract":"<p><strong>Background: </strong>Intussusception is a common cause of intestinal obstruction in children, typically occurring between 6 months and 3 years of age. While most cases are idiopathic, rare cases involve pathological lead points. Ileo-ileal intussusception is an uncommon variant, often associated with anomalies such as heterotopic pancreatic tissue.</p><p><strong>Case presentation: </strong>We report a rare case of a 2-month-old infant presenting with inconsolable crying and feeding refusal, diagnosed with ileo-ileal intussusception due to pancreatic heterotopia. Ultrasound confirmed the diagnosis, leading to successful surgical resection of the affected ileal segment, with an uneventful recovery.</p><p><strong>Conclusion: </strong>This case emphasizes the importance of considering intussusception in younger infants with nonspecific symptoms. Early imaging, particularly ultrasound, plays a critical role in timely diagnosis. Though rare, pancreatic heterotopia can act as a pathological lead point, highlighting the need for awareness and prompt surgical intervention to optimize pediatric patient outcomes.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":"251-255"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13000066/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive value of great and small saphenous vein diameters for venous reflux in lower extremity chronic venous insufficiency: A segmental analysis using duplex ultrasonography.","authors":"Somayeh Hajiahmadi, Mohammadreza Elhaie, Ali Nikkhah, Seyyed-Ali Alaei","doi":"10.1007/s40477-025-01101-z","DOIUrl":"10.1007/s40477-025-01101-z","url":null,"abstract":"<p><strong>Background: </strong>Chronic venous disease is prevalent, particularly in the form of varicose veins, and often involves saphenous vein incompetence. While correlations between vein diameters and reflux presence are established, associations with reflux duration remain underexplored. This study aimed to evaluate the relationship between great and small saphenous vein diameters and reflux durations across lower limb segments in varicose vein patients, and to determine predictive diameter thresholds for reflux.</p><p><strong>Methods: </strong>In a cross-sectional study with case-control component (2021-2023, Blinded), 753 incompetent veins were analyzed for diameter-reflux correlations using Pearson/Spearman coefficients. Reflux was defined as > 1000 ms at saphenofemoral junction (SFJ) or > 500 ms elsewhere. A subsample of 300 cases was compared to 303 healthy controls for diameter differences via t-tests and receiver operating characteristic (ROC) analyses to identify optimal cut-offs via Youden index.</p><p><strong>Results: </strong>Significant negative correlations were found proximally (SFJ: r = - 0.163, P < 0.05; cranial great saphenous vein [GSV]: r = - 0.150, P < 0.01) and positive correlation distally (mid-calf GSV: r = 0.130, P < 0.01; caudal small saphenous vein [SSV]: r = 0.300, P < 0.01). Cases had larger diameters across segments (all P < 0.001). Highest ROC accuracy was for cranial GSV (5 mm cut-off; area under curve [AUC] = 0.775; accuracy = 72.65%) and cranial SSV (3.6 mm; AUC = 0.779; accuracy = 70.02%); lowest for ankle GSV (2.3 mm; accuracy = 53.31%) and caudal SSV (2.2 mm; accuracy = 59.83%).</p><p><strong>Conclusions: </strong>Segment-specific diameter-reflux associations highlight the inadequacy of diameter alone for assessing reflux duration, necessitating comprehensive duplex ultrasound evaluation for venous insufficiency management.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":"75-83"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13000028/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145710306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound-guided percutaneous cholecystostomy for acute cholecystitis: a systematic review and meta-analysis.","authors":"Andrea Boccatonda, Alice Brighenti, Marco Musmeci, Nicola Venturoli, Livia Masi, Daniela Agostinelli, Sofia Maria Bakken, Susanna Vicari, Cosima Schiavone, Carla Serra","doi":"10.1007/s40477-026-01119-x","DOIUrl":"10.1007/s40477-026-01119-x","url":null,"abstract":"<p><strong>Background: </strong>Ultrasound-guided percutaneous cholecystostomy (US-PC) is widely used in high-risk surgical patients with acute cholecystitis. Still, success and safety rates specific to US guidance are not always distinguished within mixed 'image-guided' series.</p><p><strong>Objective: </strong>To estimate technical success, clinical success, and major complication rates of US-PC.</p><p><strong>Methods: </strong>Primary studies explicitly reporting US-PC or with separable data were included.</p><p><strong>Primary outcomes: </strong>technical success, clinical success (as defined by the study), and major adverse events (AEs). Single-arm meta-analysis using random-effects (logit, continuity correction); heterogeneity by I2 and prediction interval.</p><p><strong>Results: </strong>Four eligible single-arm studies for technical success (N = 466). Pooled technical success 99.3% (95%CI 97.8-99.8; I2 = 0%). Three studies (N = 223) reported clinical success: pooled 97.6% (95%CI 83.4-99.7; I²≈64% due to varying definitions). Two studies (N = 293) reported major AEs: pooled 1.7% (95%CI 0.7-4.1; I² = 0%). Thirty-day mortality is available from one large study (6.2%).</p><p><strong>Conclusions: </strong>In high-risk patients, US-PC demonstrates very high technical success and low major complication rates; clinical success is high but variably defined across studies. Further direct comparisons and standardized definitions are warranted.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":"25-34"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13000085/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146159049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bicuspid aortic valve phenotype relationship with aortic root morphology and elasticity.","authors":"Riza Kaya, Onur Baydar, Umit Yasar Sinan, Cuneyt Kocas, Okay Abaci, Mehmet Serdar Kucukoglu","doi":"10.1007/s40477-026-01115-1","DOIUrl":"10.1007/s40477-026-01115-1","url":null,"abstract":"<p><strong>Objective: </strong>This study examines the potential links between bicuspid aortic valve (BAV) subtype, aortic root shape, and mechanical properties in a patient cohort.</p><p><strong>Methods: </strong>We retrospectively analyzed 88 patients with BAV undergoing transesophageal echocardiography (TEE). Aortic dimensions and shapes were assessed in all participants, while mechanical properties (aortic strain, distensibility, and stiffness) were measured in 37 patients without significant valve dysfunction.</p><p><strong>Results: </strong>Among type 1 BAV with raphe (n = 51), 60.8% had type A aortic shape, 35.3% type N, and 3.9% type E. For BAV without raphe (n = 24), 54.2% had type A, 33.3% type N, and 12.5% type E. Type 2 (n = 10) and type 3 (n = 3) BAV showed varied aortic shapes without a clear pattern. Patients with raphe had superior aortic mechanics compared to those without, with higher strain (7.39 ± 2.9 vs. 5.57 ± 2.3), greater distensibility (4.13 ± 2.0 vs. 2.77 ± 1.0 cm²·dyne⁻¹·10⁻⁶), and lower stiffness (6.77 ± 4.4 vs. 8.04 ± 3.1) (p < 0.05 for all).</p><p><strong>Conclusion: </strong>Aortic shape showed no significant association with BAV subtype. However, reduced distensibility in non-raphe BAV patients suggests a potential for earlier aortic complications, necessitating longitudinal studies.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":"151-154"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13000095/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146013179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Apocrine hydroadenoma mimicking a Morton's neuroma: a rare differential diagnosis.","authors":"Daniele Carmelo Caltabiano, Maria Vittoria Raciti, Linda Reali, Giuliana Mannino, Simone Poidomani, Adriana Mangiameli, Antonio Basile, Gianluca Galvano","doi":"10.1007/s40477-024-00911-x","DOIUrl":"10.1007/s40477-024-00911-x","url":null,"abstract":"<p><p>A 62-year-old woman, with neuropathic pain and paresthesia in her right forefoot, showed a circumscribed soft tissue swelling on the sole between the second and third metatarsal. Ultrasound (US) imaging showed a well-defined lesion in the second intermetatarsal space, without vascularization sign at Power Doppler (PD). In the first hypothesis, these findings led to Morton's neuroma. Magnetic Resonance Imaging (MRI), demonstrated a dumbbell-shaped lesion between the II and the III metatarsal heads; it extended cranially to the subcutaneous fat of the dorsal slope. The MRI findings weren't compatible with a classic Morton's neuroma and were radiologically undetectable. The patient had a sub-total excisional biopsy. The anatomopathological features were specific to an apocrine hydroadenoma from an ectopic sweat gland. This rare pathology has not been previously described in the literature and it must be considered as a differential diagnosis due to the clinical presentation and the US appearance mimicking Morton's neuroma.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":"213-217"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13000013/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141428280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}