{"title":"FibroScan's evolution: a critical 20-year review.","authors":"Nisar Ahmed, Ayushi Kumari, R Srinivasa Murty","doi":"10.1007/s40477-024-00971-z","DOIUrl":"https://doi.org/10.1007/s40477-024-00971-z","url":null,"abstract":"<p><p>FibroScan, initially designed for assessing cheese maturity, has evolved into a crucial medical tool for liver fibrosis diagnosis. This systematic review explores its development history, functionality, and pros and cons compared to traditional liver biopsy. Precision in various clinical settings is scrutinised, emphasising FibroScan's accuracy in conditions like NAFLD and viral-induced liver disease. The article also delves into its potential in paediatrics, its relevance in monitoring COVID-19-related liver complications, and its role in predicting hepatocellular carcinoma risk, Technical aspects, including transducers, imaging integration, and portability, are examined. Various methods for evaluating liver fibrosis are discussed, highlighting FibroScan's suitability for advanced stages, contrasting with the gold standard of liver biopsy for early stages. The impact of FibroScan on long-term liver conditions is emphasised, focusing on early detection, progression monitoring, reduced invasive biopsies, and hepatocellular carcinoma risk prediction. This systematic review underscores FibroScan's transformative potential in liver disease treatment and predicts ongoing research to enhance early detection, disease monitoring, and explore new clinical applications. Anticipated advances include FibroScan-guided liver biopsy, artificial intelligence data analysis, and point-of-care device development, promising a further revolution in liver disease management. The article concludes with optimistic prospects for FibroScan's future.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142677697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrea Boccatonda, Marco Marcello Marcellini, Eugenio Ruggeri, Cristina Felicani, Alice Brighenti, Rossella Loiacono, Giorgio Ercolani, Carla Serra
{"title":"Ceus features of liver pecoma: a case report and literature review.","authors":"Andrea Boccatonda, Marco Marcello Marcellini, Eugenio Ruggeri, Cristina Felicani, Alice Brighenti, Rossella Loiacono, Giorgio Ercolani, Carla Serra","doi":"10.1007/s40477-024-00973-x","DOIUrl":"10.1007/s40477-024-00973-x","url":null,"abstract":"<p><p>Perivascular epithelioid cell neoplasms (PEComas) and epithelioid angiomyolipomas (EAMLs) are two different denominations for the same \"mesenchymal tumor composed of histologically and immunohistochemically distinctive perivascular epithelioid cells\". Hepatic PEComa/EAML is a very rare neoplasm, and only 29 case reports of hepatic PEComa and 25 of hepatic EAML have been reported in the current literature. A clear female predominance with a mean age at diagnosis of 42.5 years old can be observed by literature review. Ultrasound (US) examination was the first-line diagnostic technique in most of the cases of hepatic PEComa, but it was documented in very few cases of hepatic EAML. A great variability in the ultrasonographic B-mode, color Doppler and contrast-enhanced ultrasonography (CEUS) features of hepatic PEComa/EAML emerges. Computed tomography and magnetic resonance were the most common used techniques to confirm the nature of the hepatic lesion, even if the anatomo-pathological examination was the only technique to display a certainty diagnosis and to differentiate hepatic PEComa/EAML from benign and malignant hepatic lesions. The great majority of hepatic PEComas/EAMLs are surgically treated without any adjuvant therapy.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142669564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medhat Ibraheem Mohammad Ahmad, Ahmad Hussien Mohammed, Walid Ahmad Ali, Radwa Ahmed El Bahy, Mohamad Hasan Alam-Eldeen
{"title":"Diagnostic yield of transvaginal ultrasonography versus saline: infused sonohysterography in the evaluation of post-cesarean section uterine niche.","authors":"Medhat Ibraheem Mohammad Ahmad, Ahmad Hussien Mohammed, Walid Ahmad Ali, Radwa Ahmed El Bahy, Mohamad Hasan Alam-Eldeen","doi":"10.1007/s40477-024-00969-7","DOIUrl":"https://doi.org/10.1007/s40477-024-00969-7","url":null,"abstract":"<p><strong>Background: </strong>Caesarean section (CS) defects, also known as niches, refer to the discontinuity in the myometrium at the site of a previous CS. These niches pose a complication in over 50% of CS performed on Egyptian women. The primary method used to diagnose uterine niches is transvaginal ultrasound (TVU). In recent times, the use of TVU with saline- infused sonohysterography (SISH) has significantly improved the detection of uterine niches. Our objective was to assess the diagnostic performance of SISH compared to TVU in diagnosing uterine niches among non-pregnant women with previous cesarean sections (CS), by integrating the findings and demographic features of the participants.</p><p><strong>Methods: </strong>For this purpose, we conducted a cross-sectional study involving 60 non-pregnant women with a history of CS but without any known systemic cause. Each participant underwent TVU followed by SISH. We recorded and analyzed the dimensions (depth, length and width) of the niche, as well as the residual myometrial thickness (RMT) adjacent to the niche in both TVU and SISH. Additionally, we collected data on the patients' age and the number of previous CSs.</p><p><strong>Results: </strong>Our results showed that women with a CS niche detected by SISH had a significantly lower age compared to those detected by TVU. We also found a significant association between the number of previous CSs diagnosed by either TVU or SISH and the rate of CS niche detection, which increased with an increasing number of previous CSs. Furthermore, there was a significant difference in the depth, width, and residual myometrial thickness adjacent to the niche between the two procedures. All niche dimensions were significantly higher among women examined by SISH.</p><p><strong>Conclusion: </strong>Our study confirms that SISH is a superior tool for assessing uterine niches in non-pregnant women with a history of CS compared to TVU. Furthermore, the combined approach of using both SISH and TVU eliminates the need for costly hysteroscopy.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142649435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A pictorial essay on the potential use of the transhepatic subcostal ultrasound view for the evaluation of lower lung lobe pathology.","authors":"Issac Cheong, Francisco Marcelo Tamagnone","doi":"10.1007/s40477-024-00970-0","DOIUrl":"https://doi.org/10.1007/s40477-024-00970-0","url":null,"abstract":"<p><p>Lung ultrasound has become indispensable in managing critically ill patients, offering bedside evaluation capabilities for intensive care unit physicians without ionizing radiation. This noninvasive technique demonstrates high sensitivity and specificity in diagnosing various lung pathologies, including pleural effusion and consolidation syndrome. A novel trans-hepatic subcostal approach enhances visualization of the lower right lung lobe, revealing the diaphragm dome and inferior lobe through oblique coronal sections. Challenges include inadequate liver visibility hindering right lung views and difficulties in left lung assessment due to gastric interference. Despite limitations, this method proves invaluable when conventional imaging is impractical, showcasing its utility in critical care settings.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142644664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pilar Caridad Morata Barrado, Miguel Muela Méndez, Andrés Eduardo Recover Palenzona, Fernando Miguel Franch Oviedo, Julio Reina Barrera, Mercedes Guerra Requena
{"title":"Concordance between preoperative ultrasound arterial mapping in the femoropopliteal and distal sector and intraoperative angiography.","authors":"Pilar Caridad Morata Barrado, Miguel Muela Méndez, Andrés Eduardo Recover Palenzona, Fernando Miguel Franch Oviedo, Julio Reina Barrera, Mercedes Guerra Requena","doi":"10.1007/s40477-024-00967-9","DOIUrl":"https://doi.org/10.1007/s40477-024-00967-9","url":null,"abstract":"<p><strong>Aims: </strong>The present study analyzes the concordance between arterial mapping of this sector using duplex ultrasound and intraoperative angiography.</p><p><strong>Methods: </strong>A retrospective, single-center observational study was carried out. The study sample consisted of patients subjected to open or endovascular surgery of the femoropopliteal and distal sector with prior ultrasound arterial mapping from January 2017 to December 2022. Sensitivity, specificity, positive (PPV) and negative predictive values (NPV) of arterial mapping with duplex ultrasound versus intraoperative angiography were evaluated, the degree of concordance between the two techniques and the correlation between surgical planning and the surgery finally performed.</p><p><strong>Results: </strong>167 patients were analyzed. A total of 1837 segments were explored, of which 149 (8.1%) were not able to be evaluated. Regarding the global precision of ultrasound in predicting significant arterial lesions (stenosis > 50% or occlusion), sensitivity was 85.26% (95% confidence interval [95%CI]: 82.33-88.19%), specificity 88.57% (95%CI: 86.63-90.51%), PPV 80.41% (95%CI: 77.24-83.58%), and NPV 91.61% (95%CI: 89.89-93.34%). Global concordance assessed by the kappa index was 0.725 (95%CI: 0.691-759). The surgical indications based on arterial mapping coincided with the final surgery performed in 97.6% of the cases.</p><p><strong>Conclusions: </strong>Arterial mapping of the femoropopliteal and distal sector with duplex ultrasound could be considered as the sole preoperative imaging technique for surgical planning.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Soheila Borji, Hadi Sabat Sani, Saharnaz Ghorbani, Mohammad Soltani, Vahid Mohammadi, Reza Elahi
{"title":"The correlation between metabolic dysfunction-associated steatotic liver disease (MASLD) grades and hemodynamic alterations of the portal, hepatic, and splenic vein and spleen size.","authors":"Soheila Borji, Hadi Sabat Sani, Saharnaz Ghorbani, Mohammad Soltani, Vahid Mohammadi, Reza Elahi","doi":"10.1007/s40477-024-00965-x","DOIUrl":"https://doi.org/10.1007/s40477-024-00965-x","url":null,"abstract":"<p><strong>Introduction: </strong>Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease (NAFLD), is the most prevalent chronic liver condition worldwide, affecting over 25% of the population. Fatty infiltration in MASLD leads to hemodynamic changes in hepatic circulation, which can be quantitatively assessed using Color Doppler Ultrasonography (US). In this study, we aimed to investigate the correlation of Color Doppler US findings of the portal, hepatic, and splenic venous system within various degrees of MASLD.</p><p><strong>Methods and materials: </strong>Between 2021 and 2024, 104 patients referred to Mousavi Hospital at Zanjan University of Medical Sciences were enrolled. Participants were divided into four groups based on the degree of hepatic fatty infiltration on biopsy results: normal, grade 1, grade 2, and grade 3, with 26 subjects in each group (13 men and 13 women). All patients were biopsy proved. Gray-scale and Color Doppler US were used to assess portal and splenic vein peak systolic velocity (PSV), portal and splenic vein diameter, hepatic vein waveform, and spleen size. The Spearman rank correlation was employed to evaluate the relationship between these variables under non-parametric conditions.</p><p><strong>Results: </strong>A significant negative correlation was found between portal vein PSV and MASLD grade (r = - 0.499, p = 0.000). A significant difference was also observed in hepatic venous waveform abnormality between different grades of MASLD (p = 0.043). Accordingly, portal vein PSV and splenic vein PSV had a significantly positive correlation (r = 0.209, p = 0.033). We also observed a positive correlation between the portal vein and splenic diameter (r = 0.210, p = 0.032).</p><p><strong>Conclusion: </strong>Increasing MASLD severity is associated with reduced portal vein PSV and more pronounced abnormalities in hepatic vein flow. Routine assessment of portal and hepatic vein flow using Color Doppler US is recommended to accurately diagnose and monitor the effects of MASLD on hepatic circulation, potentially improving disease management and patient outcomes.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrea Garipoli, Edoardo Leone, Rita Stefanucci, Bruno Beomonte Zobel, Michele Galluzzo, Margherita Trinci
{"title":"A possible role of e-FAST in the hemodynamically stable polytrauma patient: results of a single trauma center preliminary restrospective study.","authors":"Andrea Garipoli, Edoardo Leone, Rita Stefanucci, Bruno Beomonte Zobel, Michele Galluzzo, Margherita Trinci","doi":"10.1007/s40477-024-00962-0","DOIUrl":"https://doi.org/10.1007/s40477-024-00962-0","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this work is to evaluate whether EFAST can also play a role in the hemodynamically stable polytrauma patient, without delaying his arrival in the CT-scan room.</p><p><strong>Methods: </strong>In a period of seven month, 748 polytrauma patients were retrospective valued; we analyzed the findings of the CT exams of 485 haemodynamically stable patients for whom the EFAST investigation was not requested, highlighting the possible presence of findings that, if reported during the EFAST, could have changed the patient management.</p><p><strong>Results: </strong>52 hemodynamically stable patients with CT examination findings potentially detectable by ultrasound examination directly in the shock room, which represent a percentage of about 11% of all the hemodynamically stable patients analyzed; about 54% of CT findings are represented by the presence of pneumothorax.</p><p><strong>Conclusion: </strong>Looking to the results and the sensitivity of thoracic ultrasound in identifying even small flaps of pneumothorax, the evaluation by EFAST ultrasound examination could be extended at least to all those patients with chest trauma or who require endotracheal intubation. The risk of generating a hypertensive pneumothorax following positive pressure intubation is widely known, and certainly the presence of a pre-existing layer of pneumothorax, even if of modest entity, further increases this possibility.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xing Hu, Gaobo Zhang, Rong Xie, Yong Wang, Yingfeng Zhu, Hong Ding
{"title":"Contrast-enhanced ultrasound can differentiate the level of glioma infiltration and correlate it with biological behavior: a study based on local pathology.","authors":"Xing Hu, Gaobo Zhang, Rong Xie, Yong Wang, Yingfeng Zhu, Hong Ding","doi":"10.1007/s40477-024-00961-1","DOIUrl":"https://doi.org/10.1007/s40477-024-00961-1","url":null,"abstract":"<p><strong>Purpose: </strong>The objective of this study is to assess the diagnostic efficacy of contrast-enhanced ultrasound (CEUS) in determining the level of glioma infiltration and to investigate its correlation with pathological markers.</p><p><strong>Methods: </strong>A prospective study involving 16 adult glioma patients was conducted. Preoperative US-(Magnetic Resonance)MR fusion imaging was utilized for tumor infiltration localization, while CEUS was employed to assess hemodynamic alterations. Parameters such as peak intensity (PI), rise time (RT), time to peak (TTP), and area under the curve (AUC) were measured. Utilizing contralateral normal brain tissue as the reference standard. The Kruskal-Wallis H-test was conducted to compare CEUS and pathological parameters (significance level, p < 0.05; bonferroni correction) among tumor margins, infiltration zones, and normal tissues, as well as between low-grade glioma (LGG) and high-grade glioma (HGG) within the infiltration zone, based on whole slide pathological images analysis. Spearman correlation analysis was employed to determine the correlation coefficient between hemodynamics and pathology. Receiver operating characteristic (ROC) curves were drawn to evaluate the performance of CEUS in tumor classification.</p><p><strong>Results: </strong>From tumor margin to normal tissue, PI, AUC, Ki67, EGFR, and 1p/19q showed a significant decreasing trend, while TTP, IDH-1, and MGMT gradually increased. RT was lower at the tumor margin but did not show statistically significant differences. In the infiltration zones, there was a significant increase in parameters such as PI, normalized PI (Nor_PI), AUC, and Ki67 from LGG to HGG, while RT, Nor_RT, TTP, Nor_TTP, IDH-1, and MGMT significantly decreased. Nor_AUC and EGFR increased but were not significant, and 1p/19q decreased but was not significant. RT and Nor_TTP were independent risk factors for distinguishing between LGG and HGG in the infiltration zone, with a combined diagnostic efficacy ROC of 0.891. The sensitivity reached 96.64% and the specificity reached 82.35%. There was a significant correlation between hemodynamic indicators and pathological indicators. CEUS can effectively differentiate levels of infiltration zones, which correlates with their biological behavior, with RT + Nor_TTP showing particularly highest diagnostic efficacy.</p><p><strong>Conclusion: </strong>These findings contribute to improving the accuracy of diagnosing infiltration zones and provide essential biological insights for subsequent treatments.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142569877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F J Rodríguez-Cuadrado, C Martínez-Mera, G Roustan-Gullón, F Alfageme-Roldán
{"title":"Trichosonography: ultrasound of alopecias and hair disorders.","authors":"F J Rodríguez-Cuadrado, C Martínez-Mera, G Roustan-Gullón, F Alfageme-Roldán","doi":"10.1007/s40477-024-00966-w","DOIUrl":"https://doi.org/10.1007/s40477-024-00966-w","url":null,"abstract":"<p><p>Trichology is the area of dermatology that focuses on the study, diagnosis and management of the different types of alopecia and hair and scalp disorders. In recent years, there have been great advances in the non-invasive diagnosis of these conditions, especially with trichoscopy and more recently with sonography. High frequency ultrasound study of the scalp, for which we propose the name of \"trichosonography\", may represent a valuable technique in the evaluation of both clinical and subclinical abnormalities of the hair follicle and the innermost layers of the skin, which are otherwise inaccessible to trichoscopy. The purpose of this pictorial essay is to offer a descriptive approach to the clinical and ultrasound findings of the main hair and scalp disorders.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142569927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Roberto Ceriani, Francesca Colapietro, Roberto Gabbiadini, Arianna Dal Buono, Nicola Pugliese, Chiara Masetti, Luca Brandaleone, Tiziana Ierace, Luigi Solbiati
{"title":"Ultrasound-guided percutaneous biopsy for challenging perihilar focal liver lesions: diagnostic accuracy and safety assessment.","authors":"Roberto Ceriani, Francesca Colapietro, Roberto Gabbiadini, Arianna Dal Buono, Nicola Pugliese, Chiara Masetti, Luca Brandaleone, Tiziana Ierace, Luigi Solbiati","doi":"10.1007/s40477-024-00949-x","DOIUrl":"https://doi.org/10.1007/s40477-024-00949-x","url":null,"abstract":"<p><strong>Purpose: </strong>In cases of perihilar focal liver lesions, distinguishing between benign strictures and malignancies is critical to prevent unnecessary surgery. Although the use of contrast-enhanced CT or MRI in combination with clinical and laboratory findings can aid in diagnosis, histologic examination is often necessary. Histologic specimens can be obtained through various techniques, including ERCP-guided brush cytology or intraductal biopsy, cholangioscopy-directed biopsy or endoscopic ultrasound (EUS). However, these methods have been associated with suboptimal sensitivity and specificity, sometimes leading to inconclusive results. Therefore, ultrasound-guided percutaneous biopsy (US-guided PB) may play a crucial role, but data is lacking for perihilar lesions. The objective of our study was to assess the technical feasibility and safety of US-guided PB for perihilar lesions.</p><p><strong>Methods: </strong>We included 20 consecutive patients who underwent US-guided PB of perihilar liver lesions that were not suitable for surgery between June 2018 and October 2023.</p><p><strong>Results: </strong>All samples were obtained using a Menghini needle 20G and were adequate for histological examination, with a mean diameter of 12.3 mm (range 3-40 mm). Out of the 20 patients, 11 were diagnosed with malignancy while the remaining 9 had inflammatory or fibrotic tissue samples. No adverse events related to the procedure were reported.</p><p><strong>Conclusion: </strong>US-guided PB of perihilar liver lesions is a valuable and safe diagnostic approach to consider for patients who are not suitable for surgery.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142565278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}