Journal of UltrasoundPub Date : 2024-06-01Epub Date: 2023-09-01DOI: 10.1007/s40477-023-00813-4
Ferdinando Spagnuolo
{"title":"Global use of ultrasound in newborn vascular access: RA. CE. VA: implantation and management of complications.","authors":"Ferdinando Spagnuolo","doi":"10.1007/s40477-023-00813-4","DOIUrl":"10.1007/s40477-023-00813-4","url":null,"abstract":"<p><p>The use of ultrasound is advantageous in many respects: pre-procedural vein selection, real-time venipuncture, tip navigation (to verify guidewire or catheter progression) and post-procedural tip location, detection of early (hematoma, pneumothorax, hemothorax) and late complications (cardiac tamponade, fibroblastic sleeve, thrombosis).Such assessment is best performed using a systematic and standardized approach, as the Rapid Central Vein Assessment, described in this study for neonates too.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11178687/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10503050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of UltrasoundPub Date : 2024-06-01Epub Date: 2024-02-05DOI: 10.1007/s40477-023-00866-5
Andrea Boccatonda, Fabio Piscaglia
{"title":"New perspectives on the use of artificial intelligence in the ultrasound evaluation of lung diseases.","authors":"Andrea Boccatonda, Fabio Piscaglia","doi":"10.1007/s40477-023-00866-5","DOIUrl":"10.1007/s40477-023-00866-5","url":null,"abstract":"","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11178746/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139693532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of UltrasoundPub Date : 2024-06-01Epub Date: 2024-01-28DOI: 10.1007/s40477-023-00854-9
Sietske Bergsma, Margo van Gent, Alida J Dam-Vervloet, Martine C M Lagerweij, Egbert-Jan van der Wouden, Ingrid M Nijholt, Martijn F Boomsma, Lieke Poot
{"title":"Image-guided point-shear-wave elastography: a valid and reliable technique for liver fibrotic staging.","authors":"Sietske Bergsma, Margo van Gent, Alida J Dam-Vervloet, Martine C M Lagerweij, Egbert-Jan van der Wouden, Ingrid M Nijholt, Martijn F Boomsma, Lieke Poot","doi":"10.1007/s40477-023-00854-9","DOIUrl":"10.1007/s40477-023-00854-9","url":null,"abstract":"<p><strong>Purpose: </strong>Despite progressive implementation of image-guided point-shear wave elastography (pSWE) in guidelines as an alternative to transient elastography for the staging of fibrotic liver disease, pSWE is not widely adopted in clinical workflow. More information on reliability and validity of pSWE systems is needed. Therefore, we performed a phantom study to evaluate the validity and reliability of pSWE with ultrasound systems.</p><p><strong>Methods: </strong>Validity and reliability of pSWE measurements from three ultrasound systems were evaluated. Measurements were performed on an elasticity phantom with reference elasticities of 7 ± 1 (low) (median ± interquartile range (IQR)), 14 ± 2 (medium) and 26 ± 3 (high) kPa. Measurements were repeated in tenfold for each reference at 2, 3 and 4 cm depth. Results were considered valid when median elasticity ± IQR was between the uncertainty limits (IQR) for each reference elasticity value and reliable when IQR/median < 0.30.</p><p><strong>Results: </strong>pSWE with the systems provided valid results for all reference elasticities and focal depths, except for overestimation of high reference elasticity at 2 and 4 cm depth for one system (41.5 ± 4.3 and 39.0 ± 1.2 kPa, respectively). Measurements were reliable with a maximum IQR/median of 0.13, well below the guideline of IQR/median < 0.30.</p><p><strong>Discussion: </strong>The results support the use of pSWE as an alternative to invasive or non-image guided noninvasive techniques for liver fibrotic staging.</p><p><strong>Conclusions: </strong>pSWE with ultrasound systems from different vendors is valid and reliable and can therefore be implemented to optimize clinical workflow by performing imaging and elastography simultaneously.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11178714/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139572058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prediction of bleeding in placenta accrete spectrum with lacunar surface: a novel aspect.","authors":"Fahimeh Ghotbizadeh Vahdani, Azadeh Shabani, Mohammad Haddadi, Seyedeh Mojgan Ghalandarpoor-Attar, Zahra Panahi, Sedigheh Hantoushzadeh, Sedigheh Borna, Maryam Deldar, Sanaz Ghashghaee, Mamak Shariat","doi":"10.1007/s40477-024-00878-9","DOIUrl":"10.1007/s40477-024-00878-9","url":null,"abstract":"<p><strong>Purpose: </strong>Diagnosing the placenta accreta spectrum is crucial to prevent morbidities and mortalities among women with the suspicion of this pathology. We aim to evaluate novel ultrasonography markers for these patients in diagnosing and predicting prognosis.</p><p><strong>Methods: </strong>This cross-sectional study was performed in a referral academic hospital. The population was composed of 51 pregnant women with a suspect of placenta accreta spectrum who had scheduled C-sections. Their primary information and past medical histories were documented. Then the ultrasonography markers, including the most bulging volume behind the bladder (area, perimeter, and volume), the Lacune (diameter, length, number, and surface of the largest lacuna obtained by multiplying the length by the width), the most considerable thickness of placenta on the cervix in patients with placenta previa, the most considerable thickness of the placenta behind the bladder, the Jellyfish sign, and sponge cervix were evaluated. Their comparison to the severity of the bleeding, the rate of the hysterectomy, and the following pathology of the placenta accreta spectrum were analyzed.</p><p><strong>Results: </strong>The results showed that 17 (33.3%) of patients had severe bleeding (more than 2500 cc). The diameter, length, and surface of the largest lacunae limited to women with severe bleeding were 13.50 (5.5-21) mm, 20.50 (11-56) mm, 273.00 (60-1176) mm<sup>2</sup>, and they were 11.00 (5-24) mm, 16.25 (10-39) mm, and 176.25 (50-744) mm<sup>2</sup> for women without severe bleeding (P value = 0.039, 0.027, 0.021). 13 (76.5%) women with severe bleeding had Jellyfish signs,16 (94.2%) had bulging on the cervix, and 10(58.8%) had a sponge cervix (P value = 0.046, 0.036, 0.006). Also, 34 (66.66%) patients needed hysterectomy. The diameter, length, and surface of the largest lacunae limited to women with hysterectomy were 12.00 (5-24) mm, 18.00 (11-56) mm, 231.00 (60-1176) mm<sup>2</sup>, and they were 9.00 (5-18) mm, 15.00 (10-28) mm, and 136.00(50-504) mm<sup>2</sup> for women without hysterectomy (P value = 0.012, 0.070, 0.021). 24(70.6%) women with hysterectomy had Jellyfish signs, 29 (85.3%) of them had bulging on the cervix, and 15 (44.1%) had sponge cervix (P value = 0.05, 0.036, 0.028). The cut-off associated with the Lacunar surface was 163.5 mm<sup>2</sup>. Its sensitivity was 80%, and its specificity was 48% (P value = 0.021).</p><p><strong>Conclusion: </strong>The presence of single large lacunae could be a suitable predictive factor for bleeding in the placenta accreta spectrum; Moreover, there are some other US criteria, including the presence of a sponge cervix or the Jellyfish sign that are valuable predictive factors for negative outcomes for this spectrum, including hysterectomy.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11178688/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140327406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of UltrasoundPub Date : 2024-06-01Epub Date: 2023-06-23DOI: 10.1007/s40477-023-00787-3
Tomás Fontes, Mariana Sebastião, Fernando Saraiva
{"title":"Ultrasound features of a pulley strain in a sport climber: a discussion based on a case report.","authors":"Tomás Fontes, Mariana Sebastião, Fernando Saraiva","doi":"10.1007/s40477-023-00787-3","DOIUrl":"10.1007/s40477-023-00787-3","url":null,"abstract":"<p><p>Ruptures of the annular pulleys of the finger flexor tendons are not common in the general population. In sport climbing, these structures can be abnormally stressed, mainly because of the so-called crimped position, an extreme flexion of the proximal interphalangeal joint, levering an abnormal tension by flexor tendons. Complete pulley tears manifest with explicit pain and an inability, but strains or minor tears might only be perceived by individuals like professional climbers, since they can bring total disability to crucial grip positions. Complete tears of one or more pulleys have already been characterized by ultrasound and magnetic resonance, but no imaging features were described for strains or smaller partial tears. We describe the case of a climber with symptoms of an A2-pulley injury, in whom ultrasound imaging revealed reversible features of fusiform thickening and hypoechogenicity, which resemble the strains that we find in similar structures like tendons and other ligaments.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11178689/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9679392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of UltrasoundPub Date : 2024-06-01Epub Date: 2023-12-14DOI: 10.1007/s40477-023-00839-8
Daniela Melchiorre, M Passalacqua, M Maresca, G Landi, M A Bagni, K El Aoufy, M Baccini, M Matucci-Cerinic, S Maddali Bongi
{"title":"The effect of a combined rehabilitation program on the temporomandibular joint in systemic sclerosis evaluated by ultrasound exam.","authors":"Daniela Melchiorre, M Passalacqua, M Maresca, G Landi, M A Bagni, K El Aoufy, M Baccini, M Matucci-Cerinic, S Maddali Bongi","doi":"10.1007/s40477-023-00839-8","DOIUrl":"10.1007/s40477-023-00839-8","url":null,"abstract":"<p><strong>Purpose: </strong>Temporomandibular joint (TMJ) involvement is frequent in Systemic Sclerosis (SSc). Dysfunction and X-ray changes of TMJ were described only in few observational studies. Treatment as well has been seldom considered. Aim of the present study was to evaluate the effects on TMJ of two specifically designed physiotherapy protocols.</p><p><strong>Methods: </strong>The study group included 26 SSc outpatients (22 females and 4 males with mean age ± SD 59.08 ± 10.31 years). Thirteen patients were randomly assigned to a treatment (protocol 1) including home exercises for TMJ and thirteen to a treatment (protocol 2) including home exercises and a combined procedure. The rehabilitation effects on the TMJ were evaluated by ultrasound examination (UE) in static and dynamic phases. UE was performed in all patients before and at the end of the treatment and after a follow up (8 weeks).</p><p><strong>Results: </strong>Both rehabilitation protocols induced a significant improvement (protocol 1: p < 0.01 and protocol 2: p < 0.005) of mouth opening with a long-lasting effect. Protocol 2 was more effective than protocol 1. A significant increase of bilateral condyle-head temporal bone distance was detected by UE at the end of both treatments. It was maintained at follow-up in patients treated with Protocol 2.</p><p><strong>Conclusions: </strong>The present investigation shows that a rehabilitation program characterized by home exercises with a combined procedure is useful to recover the function of TMJ. The data also show that UE is helpful in the evaluation of TMJ in SSc and in the assessment of the efficacy of the rehabilitation programs.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11178700/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138810382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of UltrasoundPub Date : 2024-06-01Epub Date: 2024-02-23DOI: 10.1007/s40477-023-00846-9
G K Sharma, A Patil, P Kaur, S Rajesh, Elena Drakonaki, Rajesh Botchu
{"title":"Comparison of efficacy of ultrasound-guided platelet rich plasma injection versus dry needling in lateral epicondylitis-a randomised controlled trial.","authors":"G K Sharma, A Patil, P Kaur, S Rajesh, Elena Drakonaki, Rajesh Botchu","doi":"10.1007/s40477-023-00846-9","DOIUrl":"10.1007/s40477-023-00846-9","url":null,"abstract":"<p><strong>Purpose: </strong>To assess whether Ultrasound guided dry needling is adequate for both common extensor tendon tears and tendinosis or whether ultrasound guided platelet rich plasma (PRP) has a superior outcome when compared to dry needling when there are tears of the common extensor tendon.</p><p><strong>Materials and methods: </strong>This is a single-centre, single-blinded, randomised controlled trial conducted between November 2018 and April 2020. 40 patients diagnosed with lateral epicondylitis based on clinical and sonographic features and having comparable baseline characteristics were randomly assigned to the two study groups (dry needling and PRP). Inclusion criteria were patients aged 20 years or more who were symptomatic for at least 3 months with sonographic evidence of lateral epicondylitis. Exclusion criteria were complete tear of common extensor tendon confirmed on ultrasound and presence of other associated diseases like osteoarthritis of shoulder and elbow.</p><p><strong>Results: </strong>There was significant improvement in the visual analogue scale pain score in PRP group compared to the dry needling group at 9 months. However, this difference was not evident at 3 and 6 months follow-up. Mean improvement in common extensor tendon thickness in PRP group (5.1 mm at 3 months and 4.3 mm at 6 months) was slightly better than dry needling (4.4 mm at 3 months and 4.0 mm at 6 months). There was no difference in tear (if present) healing between both groups at 3 months. However at 6 months follow up, PRP demonstrated significant (mean-2.5) healing in tear compared to dry needling (mean-3.1).</p><p><strong>Conclusion: </strong>Two injections of Ultrasound guided PRP are more beneficial non operative treatment compared to ultrasound guided dry needling, in lateral epicondylitis.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11178710/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139934117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Focused ultrasound heating in brain tissue/skull phantoms with 1 MHz single-element transducer.","authors":"Anastasia Antoniou, Nikolas Evripidou, Christakis Damianou","doi":"10.1007/s40477-023-00810-7","DOIUrl":"10.1007/s40477-023-00810-7","url":null,"abstract":"<p><strong>Purpose: </strong>The study aims to provide insights on the practicality of using single-element transducers for transcranial Focused Ultrasound (tFUS) thermal applications.</p><p><strong>Methods: </strong>FUS sonications were performed through skull phantoms embedding agar-based tissue mimicking gels using a 1 MHz single-element spherically focused transducer. The skull phantoms were 3D printed with Acrylonitrile Butadiene Styrene (ABS) and Resin thermoplastics having the exact skull bone geometry of a healthy volunteer. The temperature field distribution during and after heating was monitored in a 3 T Magnetic Resonance Imaging (MRI) scanner using MR thermometry. The effect of the skull's thickness on intracranial heating was investigated.</p><p><strong>Results: </strong>A single FUS sonication at focal acoustic intensities close to 1580 W/cm<sup>2</sup> for 60 s in free field heated up the agar phantom to ablative temperatures reaching about 90 °C (baseline of 37 °C). The ABS skull strongly blocked the ultrasonic waves, resulting in zero temperature increase within the phantom. Considerable heating was achieved through the Resin skull, but it remained at hyperthermia levels. Conversely, tFUS through a 1 mm Resin skull showed enhanced ultrasonic penetration and heating, with the focal temperature reaching 70 °C.</p><p><strong>Conclusions: </strong>The ABS skull demonstrated poorer performance in terms of tFUS compared to the Resin skull owing to its higher ultrasonic attenuation and porosity. The thin Resin phantom of 1 mm thickness provided an efficient acoustic window for delivering tFUS and heating up deep phantom areas. The results of such studies could be particularly useful for accelerating the establishment of a wider range of tFUS applications.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11178743/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10255068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of UltrasoundPub Date : 2024-06-01Epub Date: 2024-02-25DOI: 10.1007/s40477-023-00858-5
Rida Salman, Livja Mertiri, Victor J Seghers, Desi M Schiess, HaiThuy N Nguyen, Andrew C Sher, Marla B K Sammer
{"title":"Ultrasound imaging of bowel obstruction in neonates.","authors":"Rida Salman, Livja Mertiri, Victor J Seghers, Desi M Schiess, HaiThuy N Nguyen, Andrew C Sher, Marla B K Sammer","doi":"10.1007/s40477-023-00858-5","DOIUrl":"10.1007/s40477-023-00858-5","url":null,"abstract":"<p><p>Bowel obstruction (BO) in children has a wide differential diagnosis, ranging from non-urgent conditions to surgical emergencies. Abdominal radiographs are most often used as the first imaging modality for the evaluation of obstruction. However, for some indications, ultrasound can be the primary imaging modality. Therefore, it is incumbent on radiologists to recognize the types of bowel obstruction that can be recognized with US. Key sonographic features of BO include differential dilation of bowel loops, bowel wall thickening, and free fluid. \"Do Not Miss\" findings that indicate need for emergent treatment include volvulus, pneumoperitoneum, and/or signs of ischemia (bowel wall thinning and/or absent perfusion). The aim of this pictorial essay is to provide guidance on the sonographic technique and findings that enable identification of BO on US. Examples of neonatal BO on US, including common and less frequently encountered etiologies, are illustrated in this pictorial essay.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11178722/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139944685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of UltrasoundPub Date : 2024-06-01Epub Date: 2024-03-27DOI: 10.1007/s40477-023-00850-z
Niranjan Yadav, Rajeshwar Dass, Jitendra Virmani
{"title":"A systematic review of machine learning based thyroid tumor characterisation using ultrasonographic images.","authors":"Niranjan Yadav, Rajeshwar Dass, Jitendra Virmani","doi":"10.1007/s40477-023-00850-z","DOIUrl":"10.1007/s40477-023-00850-z","url":null,"abstract":"<p><p>Ultrasonography is widely used to screen thyroid tumors because it is safe, easy to use, and low-cost. However, it is simultaneously affected by speckle noise and other artifacts, so early detection of thyroid abnormalities becomes difficult for the radiologist. Therefore, various researchers continuously address the limitations of sonography and improve the diagnosis potential of US images for thyroid tissue from the last three decays. Accordingly, the present study extensively reviewed various CAD systems used to classify thyroid tumor US (TTUS) images related to datasets, despeckling algorithms, segmentation algorithms, feature extraction and selection, assessment parameters, and classification algorithms. After the exhaustive review, the achievements and challenges have been reported, and build a road map for the new researchers.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11178762/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140307773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}