Journal of Ultrasound最新文献

{"title":"Ultrasound and strain elastography in the intensive care setting for assessment of adult sarcopenia bedside.","authors":"Carolina Zúñiga, María Lourdes Posadas, Leandro Seoane","doi":"10.1007/s40477-025-01100-0","DOIUrl":"10.1007/s40477-025-01100-0","url":null,"abstract":"<p><strong>Study design: </strong>Descriptive observational cohort study.</p><p><strong>Setting: </strong>Hospital Municipal de Derqui in Argentina, Buenos Aires, Pilar.</p><p><strong>Aim: </strong>To assess the prevalence of malnutrition in patients admitted to the Intensive Care Unit (ICU) in the Hospital Municipal de Derqui January 2023 to January 2024.</p><p><strong>Methods: </strong>An observational cohort prospective study of consecutive patients admitted to the ICU. We carried out measurement of muscle thickness (MT) of the rectus femoris and vastus intermedius on day 3 and 10 of ICU stay as well as strain elastography ratio (SER).</p><p><strong>Results: </strong>A total of 21 patients completed the study. The average loss in centimeters of the rectus femoris section was 2.9 cm (16.6 cm SD 4 on day 3 vs 14.8 cm SD 5 on day 10, p 0.05). For the vastus medialis, it was 2.6 cm (13.4 cm SD 3.5 on day 3 vs 10.8 cm SD 4.7 on day 10, p 0.02). The average SER was 1.13 (CI 0.69-1.56), with a non-significant p-value of 0.53.</p><p><strong>Conclusions: </strong>There is a significant loss of MT in critical patients during the first days of hospitalization as measured by ultrasound, while SER showed a trend towards increased muscle stiffness. Further research is needed to determine its usefulness in the early detection of changes in muscle quality. Ultrasonography emerges as a practical and accessible tool for monitoring muscle mass in critical patients.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":"65-74"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13000030/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145822115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intracervical lakes as a novel sonographic potential marker for placenta accreta spectrum: a prospective observational study.","authors":"Mohamed Hassan M Abd Elghfar, Saad Abdelnaby Ahmed E L Gelany, Mohammed Khairy Abdel Hakeem Ahmed, Mohamed Adel Abdel Rashed, Islam Yousry Tammam Abdel Maged Mohammed, Heba Hassan Ahmed","doi":"10.1007/s40477-025-01104-w","DOIUrl":"10.1007/s40477-025-01104-w","url":null,"abstract":"<p><strong>Background: </strong>Placenta accreta spectrum (PAS) is a major cause of obstetric hemorrhage and maternal morbidity. Accurate antenatal prediction is vital for surgical planning. Conventional ultrasound markers such as placental lacunae and myometrial thinning have limited specificity. Novel markers, including intracervical lakes (ICL) and absence of the cleavage line, may improve diagnostic accuracy.</p><p><strong>Methods: </strong>A prospective observational study was conducted at Minia University Maternity Hospital (March 2024-February 2025). A total of 150 women with placenta previa were enrolled and classified by intraoperative blood loss: < 2500 mL (n = 86) and ≥ 2500 mL (n = 64). All underwent standardized preoperative ultrasound evaluation, including traditional and novel markers. Intraoperative findings were the reference standard.</p><p><strong>Results: </strong>Massive bleeding occurred in 64 women (42.7%) who required longer operative times, more transfusions, and had higher rates of hysterectomy (18.8% vs. 0%) and bladder injury (60.9% vs. 12.8%) than controls (all p < 0.001). Traditional ultrasound signs showed only moderate accuracy; lacunae grade > 2 had 88% sensitivity, 53% specificity, and an AUC of 0.78. In contrast, ICL achieved 97% sensitivity, 98% specificity, and an AUC of 0.99 (95% CI 0.94-1.00). Absence of the line of cleavage also performed well (96% sensitivity, 85% specificity, AUC = 0.90). Neonatal outcomes did not differ significantly (p > 0.05).</p><p><strong>Conclusion: </strong>Novel ultrasound markers, especially ICL and the absence of the cleavage line, provide superior accuracy for predicting PAS and massive bleeding in placenta previa. Incorporating these signs into routine assessment can improve risk stratification, surgical preparedness, and reduce maternal morbidity.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":"93-105"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13000062/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145783565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tuberculous pleural effusion: integrating thoracic ultrasound and medical thoracoscopy in the diagnosis and management: a pictorial narrative review and an algorithm proposal.","authors":"Riccardo Inchingolo, Lorenzo Carriera, Simone Ielo, Roberto Barone, Andrea Smargiassi, Roberto Lipsi, Stefano Baglioni, Raffaele Scala, Roberto Magri, Giampietro Marchetti","doi":"10.1007/s40477-025-01094-9","DOIUrl":"10.1007/s40477-025-01094-9","url":null,"abstract":"<p><p>Tuberculous pleural effusion (TPE) is currently the most common form of extrapulmonary tuberculosis and remains a significant cause of pleural disease worldwide, particularly in endemic regions. It often presents with non-specific clinical symptoms, such as fever, chest pain, cough and weight loss, thereby complicating the diagnostic process. This narrative review provides an expert comprehensive clinical practice overview covering the following issues correlated with diagnosis and management of TPE: 1- epidemiology, clinical presentation and underlying pathophysiology; 2- limitations of conventional diagnostic procedures on pleural fluid; 3- usefulness of thoracic ultrasound (TUS) in the stepwise pathway 4- role of thoracoscopy as a golden diagnostic tool, with the proposal of a step by step algorithm. A large iconography enriches the review from the educational point of view by presenting a pictorial series of characteristic sonographic and thoracoscopic findings.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":"1-11"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13000056/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145423345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hepatic elastography findings among patients with chronic hepatitis B and C at King Faisal Hospital Rwanda.","authors":"François Xavier Niyitegeka, Florien Ndagijimana, Emile Twagirumukiza, Mukabagorora Theonille, James Senoga","doi":"10.1007/s40477-026-01120-4","DOIUrl":"10.1007/s40477-026-01120-4","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Hepatic elastography is a reliable, non-invasive imaging technique for assessing liver stiffness, aiding in the diagnosis of liver fibrosis and cirrhosis. Chronic hepatitis B (CHB) and chronic hepatitis C (CHC) contribute significantly to progressive liver disease and hepatocellular carcinoma (HCC) worldwide. Early detection and continuous monitoring of liver stiffness are crucial for effective disease management. However, data on hepatic elastography findings in Rwanda remain limited. This study aimed to describe hepatic elastography findings in patients with CHB and CHC at King Faisal Hospital; describe elastography findings difference in hepatitis B and C and Assess the correlation between demographic and clinical factors and fibrosis severity.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A cross-sectional study was conducted among 149 patients with CHB and CHC. Liver stiffness was assessed using point shear wave elastography (pSWE) on the Siemens Acuson Sequoia ultrasound system. Demographic data, liver function tests, viral loads, and fibrosis staging were collected and analyzed using R and R Studio (v.4.3.3). Descriptive statistics were computed, Fisher's exact test was used to assess associations, and multinomial logistic regression was applied to identify key contributors to fibrosis severity. Model accuracy, sensitivity, and specificity were also evaluated.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Of the 149 participants, 77 (52%) had CHB and 72 (48%) had CHC. Severe fibrosis (F3-F4) was significantly more prevalent in CHC patients (72%) than in CHB patients (28%) (p = 0.011). Age was a strong predictor of fibrosis severity; patients over 40 years were 10.3 times more likely to have advanced fibrosis (p = 0.002). Other significant predictors included patient with longer infection duration (7-12 years), hepatic steatosis, abnormal viral load, and without on antiviral therapy (p &lt; 0.001). Elevated AST, ALT, and GGT were strongly associated with advanced fibrosis (p &lt; 0.001). Sex was not significantly associated with fibrosis severity. Elastography findings correlated well with biopsy results, with 84% of patients classified as F3-F4 by elastography confirmed to have advanced fibrosis by biopsy.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;This study confirms that hepatic elastography is a powerful, non-invasive diagnostic tool for assessing liver fibrosis in patients with chronic hepatitis B and C. Advanced fibrosis and cirrhosis were significantly more prevalent among hepatitis C patients. Several clinical and demographic factors including older age, longer infection duration, hepatic steatosis observed on routine abdominal ultrasound, abnormal viral load, and lack of antiviral therapy were strongly associated with increased liver stiffness. Elevated liver enzymes (AST, ALT, GGT) also showed a significant correlation with fibrosis severity. Sex was not found to be a statistically significant predictor of fibrosis stage. These findings rea","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":"189-198"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13000018/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146183225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolated spontaneous non-insertional tear of the iliopsoas tendon in an elderly patient: significance of ultrasound imaging.","authors":"S Chapala, S Mettu, K Shirodkar, Karthikeyan P Iyengar, D Beale, Rajesh Botchu","doi":"10.1007/s40477-024-00945-1","DOIUrl":"10.1007/s40477-024-00945-1","url":null,"abstract":"<p><p>Isolated spontaneous tears in the non-insertional portion of the iliopsoas tendon without any underlying injury are uncommon, especially among elderly individuals. We describe the case of an 88-year-old man who experienced right groin pain caused by a spontaneous non-insertional tear in the iliopsoas tendon identified through ultrasound and confirmed via MRI. Ultrasound revealed hypoechogenicity in the non-insertional portion of the iliopsoas tendon, leading to quick identification and conservative treatment and resulting in positive functional outcomes. This case report emphasises the significance of considering spontaneous non-insertional iliopsoas tendon tears when evaluating cases of acute groin pain. This finding underscores the effectiveness of ultrasound as an initial diagnostic tool for the early cost-effective diagnosis of soft tissue injuries around the hip joint, especially in low-resource settings. Timely detection and management can help avoid unnecessary operative interventions and facilitate faster and better recovery.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":"219-224"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13000077/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141767982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of speckle-tracking echocardiography in diagnosing reverse Takotsubo syndrome in the intensive care unit.","authors":"Issac Cheong, Pablo Martín Merlo, Francisco Marcelo Tamagnone","doi":"10.1007/s40477-025-01031-w","DOIUrl":"10.1007/s40477-025-01031-w","url":null,"abstract":"<p><p>Takotsubo cardiomyopathy (TCM), often referred to as broken heart syndrome, presents as a temporary dysfunction of the heart's left ventricle (LV) apex, resembling a heart attack but without any blockage in the coronary arteries. Reverse TCM, a less common variant, is characterized by abnormal heart muscle contractions primarily affecting the basal and midventricular segments. We report a case of a 76-year-old patient undergoing hip surgery who developed reverse TCM, diagnosed through echocardiography with speckle tracking in the intensive care unit (ICU). Intraoperatively, the patient experienced shock necessitating ICU admission and mechanical ventilation. Point-of-care ultrasound revealed bilateral B-lines compatible with pulmonary edema and severe deterioration of LV function. Speckle-tracking echocardiography (STE) demonstrated a LV global longitudinal strain (GLS) of - 11% with an abnormal bull's eye pattern consistent with reverse TCM. Subsequent coronary angiography ruled out ischemic cardiomyopathy. Inotropic support improved the patient's condition, with subsequent lung ultrasound demonstrating normal aeration. Follow-up echocardiography exhibited improved cardiac function, with the speckle-tracking mode showing improvement in the bull's eye pattern and GLS. Reverse TCM, although rare, can occur in postoperative settings and necessitates prompt diagnosis and management. STE holds promise as a valuable tool for its detection and monitoring, particularly in critical care settings.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":"243-250"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13000031/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144276571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of intraoperative ultrasound during lateral extracavitary approach in thoracic disc herniation surgery. Tips and tricks for lateral approaches.","authors":"Fernando García Pérez, Mario Gomar Alba, José Javier Guil Ibáñez, Jesús Alberto Sánchez Hernández, Antonio Huete Allut, Antonio José Vargas López","doi":"10.1007/s40477-025-01093-w","DOIUrl":"10.1007/s40477-025-01093-w","url":null,"abstract":"<p><p>Thoracic disc herniation (TDH) is one of the most complex and technically challenging pathologies in spine surgery. Multiple approaches have been described to manage this condition, including the lateral extracavitary approach (LECA). The use of intraoperative ultrasound (IOUS) has been scarcely described in TDH surgery and the available experiences have been limited to posterolateral approaches. To our knowledge, the implementation of IOUS in LECA-based surgery has not yet been described in the literature. In this article, we describe how we use IOUS in these cases, including our step-by-step technique and its potential benefits. We performed LECA-based surgery to treat a T10-T11 predominantly central calcified TDH in a 55-year-old patient with severe neurological deficit of lower limbs. On the one hand, LECA provided us an excellent view of the anterior midline aspect of the spinal canal. On the other hand, we used IOUS to ensure the location and degree of resection of the TDH. There were no major technical difficulties during its use. We achieved gross total resection of the TDH and the patient progressively regained mobility in the lower limbs.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":"205-211"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13000009/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145402723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical utility of 140-degree scan angle wide-view ultrasound for comprehensive liver and spleen imaging.","authors":"Seung-Seob Kim, Jong Keon Jang, Dong Ho Lee","doi":"10.1007/s40477-026-01117-z","DOIUrl":"10.1007/s40477-026-01117-z","url":null,"abstract":"<p><strong>Purpose: </strong>Abdominal ultrasound (US) is widely used but often limited by restricted field of view. This study aimed to evaluate hepatic and splenic visualization using wide-view US with a 140° scan angle compared with the routine-view technique in patients undergoing abdominal US.</p><p><strong>Methods: </strong>In this retrospective study, 258 patients who underwent scheduled abdominal US were included. Each patient received two scans, routine view (70°) and wide view (140°), performed by two experienced radiologists. Two readers independently assigned LI-RADS visualization scores (VIS-A, no or minimal limitations; VIS-B, moderate limitations; and VIS-C, severe limitations) and assessed whether the left lateral segment tip, segment VI tip, and right diaphragm were clearly visualized. Spleen length was measured on both US scans and, when available, on CT or MR images obtained within one year. Proportions were compared using the McNemar test, and agreement of spleen size between US and CT/MR was assessed using the concordance correlation coefficient.</p><p><strong>Results: </strong>Wide-view US yielded a higher proportion of visualization score VIS-A than routine-view imaging for both readers (81.0-86.8% vs. 67.4-71.7%; P < 0.001). Coverage of the left lateral segment tip (96.9-98.4% vs 67.8-77.5%) and segment VI tip (89.5-97.3% vs 75.6-84.1%) was also higher on wide view (P < .001). The right diaphragm was more clearly visualized on wide view (89.1-94.6% vs 59.7-69.8%; P < .001). Agreement of spleen size with CT/MR was higher for wide-view than routine-view imaging (0.831 vs 0.772).</p><p><strong>Conclusion: </strong>Wide-view US significantly improved hepatic visualization and spleen measurement accuracy, enabling more comprehensive evaluation.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":"181-187"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13000075/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146159105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound-guided infiltration of the pudendal nerve: a technical approach for neuropathic pain management.","authors":"Fabio Vita, Danilo Donati, Federico Vender, Roberto Tedeschi, Salvatore Massimo Stella, Adriano Drago, Stefano Galletti, Laura Langone, Marco Miceli, Cesare Faldini","doi":"10.1007/s40477-025-01106-8","DOIUrl":"10.1007/s40477-025-01106-8","url":null,"abstract":"<p><strong>Purpose: </strong>Pudendal neuropathy is a debilitating condition often underdiagnosed due to its complex clinical presentation and overlapping symptoms with other pelvic disorders. This review aims to provide an updated synthesis of anatomical, clinical, and technical aspects of ultrasound-guided pudendal nerve infiltration, highlighting its diagnostic and therapeutic relevance in neuropathic pelvic pain.</p><p><strong>Methods: </strong>A narrative analysis was conducted of the pudendal nerve's anatomy, etiologies of neuropathy, clinical manifestations, diagnostic tools, and image-guided intervention strategies. Particular attention was dedicated to high-resolution ultrasound (HRUS) for anatomical visualization and to the technical considerations underlying perineural injection procedures.</p><p><strong>Results: </strong>Perineural infiltration of the pudendal nerve provides immediate, partial pain relief after anesthetic administration, with the addition of corticosteroids contributing to sustained relief. Ultrasound guidance minimizes complications and has proven superior to traditional landmark-based approaches. The technique demonstrates feasibility, safety, and reproducibility in clinical practice, for both diagnostic and therapeutic purposes. However, clinical results have varied, and repeated sessions or integration with multimodal strategies, including physical therapy, drug therapy, and lifestyle modifications, have often been required.</p><p><strong>Conclusion: </strong>Ultrasound-guided pudendal nerve infiltration is a minimally invasive, safe, and effective technique for both diagnosis and treatment of pudendal neuropathy. While offering rapid pain relief and confirming nerve involvement, infiltrations should be considered as part of a broader multimodal management strategy. Future directions include standardization of protocols, refinement of imaging guidance, and exploration of novel injectates or regenerative therapies to optimize long-term outcomes.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":"199-204"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13000024/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145953875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic accuracy of Doppler Sonography of hepatic blood vessels in the detection of significant liver fibrosis: a systematic review and meta-analysis.","authors":"R A Nmai, Y A Wiafe, A Donkor, I C Anyitey-Kokor, T K Adu-Bredu, S O Antwi, L R Roberts","doi":"10.1007/s40477-026-01121-3","DOIUrl":"10.1007/s40477-026-01121-3","url":null,"abstract":"<p><strong>Purpose: </strong>This systematic review and meta-analysis aimed to evaluate the diagnostic accuracy of Doppler ultrasound indices specifically the hepatic vein resistive index (HVRI) and hepatic artery resistive index (HARI) for detecting significant liver fibrosis (≥ F2), using liver biopsy as the reference standard. The key research question was whether HVRI and HARI can reliably detect significant fibrosis in chronic liver disease.</p><p><strong>Methods: </strong>A comprehensive search was conducted across PubMed, Web of Science, Cochrane Library, and Scopus. Eligible studies assessed HVRI or HARI against biopsy-confirmed fibrosis grades. Pooled sensitivity and specificity were calculated using a random-effects model to account for inter-study heterogeneity. Four studies met the inclusion criteria.</p><p><strong>Results: </strong>HVRI demonstrated high diagnostic accuracy, with pooled sensitivity of 91% (95% CI, 0.75-0.97; I² = 69%) and specificity of 89% (95% CI, 0.84-0.93; I² = 11%). In contrast, HARI showed lower sensitivity of 65% (95% CI, 0.44-0.81; I² = 82%) and specificity of 60% (95% CI, 0.42-0.76; I² = 81.2%). ROC curve analysis confirmed the superior performance of HVRI over HARI.</p><p><strong>Conclusion: </strong>HVRI shows high diagnostic accuracy for significant liver fibrosis in the research context but its translation to routine clinical use is inhibited by high heterogeneity, operator dependency and reproducibility. Further validation in diverse and low-resource populations with standardized protocols is essential to establish its clinical utility and expand accessibility.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":" ","pages":"13-24"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13000044/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146183307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}