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Chemistry of Natural Compounds最新文献

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Secondary Metabolites of Nelumbo nucifera cv. Rosa-plena Nelumbo nucifera cv的第二代谢物。Rosa-plena
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2025-11-20 DOI: 10.1007/s10600-025-04861-6
C. F. Chen, C. L. Kao, S. T. Huang, S. T. Tai, C. Y. Chen, H. T. Li
{"title":"Secondary Metabolites of Nelumbo nucifera cv. Rosa-plena","authors":"C. F. Chen, C. L. Kao, S. T. Huang, S. T. Tai, C. Y. Chen, H. T. Li","doi":"10.1007/s10600-025-04861-6","DOIUrl":"10.1007/s10600-025-04861-6","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"61 6","pages":"1221 - 1223"},"PeriodicalIF":0.9,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145847872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Index of Natural Objects 自然物索引
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2025-11-20 DOI: 10.1007/s10600-025-04873-2
{"title":"Index of Natural Objects","authors":"","doi":"10.1007/s10600-025-04873-2","DOIUrl":"10.1007/s10600-025-04873-2","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"61 6","pages":"1265 - 1265"},"PeriodicalIF":0.9,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145847880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thioureas of the (–)-Cytisine Series with Mnestic Activity 具有遗忘活性的(-)-胞氨酸系列硫脲
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2025-11-20 DOI: 10.1007/s10600-025-04854-5
A. V. Koval’skaya, V. A. Sorokina, S. F. Gabdrakhmanova, N. S. Makara, T. A. Sapozhnikova, I. P. Tsypysheva
{"title":"Thioureas of the (–)-Cytisine Series with Mnestic Activity","authors":"A. V. Koval’skaya,&nbsp;V. A. Sorokina,&nbsp;S. F. Gabdrakhmanova,&nbsp;N. S. Makara,&nbsp;T. A. Sapozhnikova,&nbsp;I. P. Tsypysheva","doi":"10.1007/s10600-025-04854-5","DOIUrl":"10.1007/s10600-025-04854-5","url":null,"abstract":"<p>The mnestic activity of synthetic derivatives of the alkaloid (–)-cytisine with a thiourea substituent in the 3- and 9-position was studied in a conditioned passive avoidance response (CPAR) test. Four candidate compounds with mnestic activity comparable to or exceeding that of the reference drug piracetam were identified among 26 tested derivatives. One of the compounds, the ethyl ester of 2{3-[(1<i>R</i>,5<i>S</i>)-3-methyl-8-oxo-2,3,4,5,6,8-hexahydro-1<i>H</i>-1,5-methanopyrido[1,2-<i>a</i>][1,5]diazocin-9-yl]thioureido}acetic acid, which was prepared by reacting methylcytisine 9-isothiocyanate with ethyl glycinate, exhibited 100% mnestic activity.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"61 6","pages":"1185 - 1190"},"PeriodicalIF":0.9,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145847871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chemical Composition of Euphorbia monostyla and Their Biological Activity 大戟化学成分及其生物活性研究
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2025-11-20 DOI: 10.1007/s10600-025-04865-2
Atabay Kokanov, H. Yang, D. Tang, Artyk Kokanov, J. Zhao, H. A. Aisa
{"title":"Chemical Composition of Euphorbia monostyla and Their Biological Activity","authors":"Atabay Kokanov,&nbsp;H. Yang,&nbsp;D. Tang,&nbsp;Artyk Kokanov,&nbsp;J. Zhao,&nbsp;H. A. Aisa","doi":"10.1007/s10600-025-04865-2","DOIUrl":"10.1007/s10600-025-04865-2","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"61 6","pages":"1236 - 1238"},"PeriodicalIF":0.9,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145847947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metabolites from Antrodia camphorata with Anti-Melanoma Activity 具有抗黑色素瘤活性的樟芝代谢物
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2025-11-20 DOI: 10.1007/s10600-025-04860-7
Yu-Hsin Wang, Kuei-Ling Huang, Der-An Tsao, Cheng-Kuang Wang, Ching-Hsiao Lee, Chung-Yi Chen
{"title":"Metabolites from Antrodia camphorata with Anti-Melanoma Activity","authors":"Yu-Hsin Wang,&nbsp;Kuei-Ling Huang,&nbsp;Der-An Tsao,&nbsp;Cheng-Kuang Wang,&nbsp;Ching-Hsiao Lee,&nbsp;Chung-Yi Chen","doi":"10.1007/s10600-025-04860-7","DOIUrl":"10.1007/s10600-025-04860-7","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"61 6","pages":"1217 - 1220"},"PeriodicalIF":0.9,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145847877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Some Chemical Features and Fatty Acid Compositions of the Seeds of Some Peanut Varieties 几种花生种子的化学特征及脂肪酸组成
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2025-11-20 DOI: 10.1007/s10600-025-04859-0
Selim Ozdemir, Kagan Kokten, Erdal Cacan, Celile Aylin Oluk
{"title":"Some Chemical Features and Fatty Acid Compositions of the Seeds of Some Peanut Varieties","authors":"Selim Ozdemir,&nbsp;Kagan Kokten,&nbsp;Erdal Cacan,&nbsp;Celile Aylin Oluk","doi":"10.1007/s10600-025-04859-0","DOIUrl":"10.1007/s10600-025-04859-0","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"61 6","pages":"1213 - 1216"},"PeriodicalIF":0.9,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145847876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis of A-azepano-moradiol and Related Compounds from 28-oxo-allobetulone 28-氧-别别土酮合成a -氮杂二醇及其相关化合物
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2025-11-19 DOI: 10.1007/s10600-025-04842-9
A. V. Terekhova, O. B. Kazakova
{"title":"Synthesis of A-azepano-moradiol and Related Compounds from 28-oxo-allobetulone","authors":"A. V. Terekhova,&nbsp;O. B. Kazakova","doi":"10.1007/s10600-025-04842-9","DOIUrl":"10.1007/s10600-025-04842-9","url":null,"abstract":"<p>A synthetic scheme for new triterpene A-azepano-oleananes with 19<i>β</i>,28-diol and 18(19)-ene fragments was demonstrated using modification of 28-oxo-allobetulone on rings A and E as an example. Cytotoxicity screening on an NCI-60 panel revealed activity for A-azepano-olean-19<i>β</i>,28-diol <b>5</b> against three types of human cancer cells with the highest activity against COLO 205 colon cancer. A-azepano-moradiol <b>10</b> was active against five types of cells with an inhibitory interval of 31.88–6.16%, while <i>N</i>-<i>tert</i>-butyloxycarbonyl-azepane <b>11</b> inhibited the growth of six types of cancer cells (from 31.84 to 14.32%), including MCF7 breast cancer, MDA-MB-468, and HCT-116 colon cancer cells.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"61 6","pages":"1129 - 1133"},"PeriodicalIF":0.9,"publicationDate":"2025-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145847780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Three New Sesquiterpenoids from Aphanamixis polystachya 山参中三个新的倍半萜类化合物
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2025-11-19 DOI: 10.1007/s10600-025-04837-6
Yan-Wu Chen, Shi-Li Wu, Fa-Wu Dong, Rui Yang, Hong-Ping He
{"title":"Three New Sesquiterpenoids from Aphanamixis polystachya","authors":"Yan-Wu Chen,&nbsp;Shi-Li Wu,&nbsp;Fa-Wu Dong,&nbsp;Rui Yang,&nbsp;Hong-Ping He","doi":"10.1007/s10600-025-04837-6","DOIUrl":"10.1007/s10600-025-04837-6","url":null,"abstract":"<p>Three new sesquiterpenoids, aphanamols S–U (<b>1–3</b>), were isolated from the 90% EtOH extract of the stems and leaves of <i>Aphanamixis polystachya</i> (Wall.) R. Parker (Meliaceae). Compound <b>1</b> is the first trinor-guaiane sesquiterpenoid isolated from the genus <i>Aphanamixis</i>, and the structures of these new compounds were established mainly by analysis of the NMR and MS data. The antifungal activities of compounds <b>1–3,</b> applied alone or in combination with fluconazole against drug-resistant <i>Candida albicans</i> were evaluated.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"61 6","pages":"1108 - 1112"},"PeriodicalIF":0.9,"publicationDate":"2025-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145847925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Two New Antibacterial Benzo[c]Oxepins from Cultures of the Fungus Xylaria polymorpha 两种新型抗菌苯并[c]Oxepins
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2025-11-19 DOI: 10.1007/s10600-025-04836-7
Rong-Xin Yang, Heng Yao, Gao-Kun Zhao, Guang-Hai Zhang, Yu-Ping Wu, Guang-Hui Kong, Feng-Xian Yang
{"title":"Two New Antibacterial Benzo[c]Oxepins from Cultures of the Fungus Xylaria polymorpha","authors":"Rong-Xin Yang,&nbsp;Heng Yao,&nbsp;Gao-Kun Zhao,&nbsp;Guang-Hai Zhang,&nbsp;Yu-Ping Wu,&nbsp;Guang-Hui Kong,&nbsp;Feng-Xian Yang","doi":"10.1007/s10600-025-04836-7","DOIUrl":"10.1007/s10600-025-04836-7","url":null,"abstract":"<p>Two new benzo[c]oxepins (<b>1</b> and <b>2</b>), together with three known analogues (<b>3–5</b>) were isolated from the cultures of the fungus <i>Xylaria polymorpha</i>. Their structures were determined by means of HR-ESI-MS and extensive 1D and 2D NMR spectroscopic studies. Compounds <b>1</b> and <b>2</b> were evaluated for their antibacterial activities against five nitrosobacteria strains (<i>Nitrosomonas communis</i><i>, </i><i>Nitrosomonas nitrosa</i><i>, </i><i>Nitrosospira multiformis</i><i>, </i><i>Nitrobacter winogradskyi,</i> and <i>Nitrospira inopinata</i>). Interestingly, compounds <b>1</b> and <b>2</b> exhibited notable antibacterial activity with bacteriostatic diameters within the range 14.8–21.8 mm against five nitrosobacteria strains, and some of the bacteriostatic diameters are greater than that of the positive control. Owing to the nitrosobacteria having the ability to convert nitrogen components into nitrite in tobacco, and then convert to tobacco-specific nitrosamines (TSNAs), compounds <b>1</b> and <b>2</b> have the potential to reduce TSNAs in tobacco by inhibiting nitrosobacteria during the fermentation process of tobacco leaves.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"61 6","pages":"1103 - 1107"},"PeriodicalIF":0.9,"publicationDate":"2025-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145847934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biflavonoid Derivatives with Hepatoprotective Activities from the Fruits of Citrus medica var. sarcodactylis 柑橘果实中具有保肝活性的类双黄酮衍生物
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2025-11-19 DOI: 10.1007/s10600-025-04834-9
Rong-Rui Wei, Wen-Min Liu, Qin-Ge Ma
{"title":"Biflavonoid Derivatives with Hepatoprotective Activities from the Fruits of Citrus medica var. sarcodactylis","authors":"Rong-Rui Wei,&nbsp;Wen-Min Liu,&nbsp;Qin-Ge Ma","doi":"10.1007/s10600-025-04834-9","DOIUrl":"10.1007/s10600-025-04834-9","url":null,"abstract":"<p>A new biflavonoid derivative, named 4′,5′′-dimethoxy-6,7-(4′′′′,5′′′′-dimethoxy-9′′′′-hydroxymethyl)- phenylpropyl-2′′-(4′′′-hydroxyphenyl)-biflavonoid (<b>1</b>), and seven known biflavonoid derivatives (<b>2–8</b>) were isolated from <i>Citrus medica</i> var. <i>sarcodactylis</i> (Siebold ex Hoola van Nooten) Swingle for the first time. These compounds were elucidated by analyzing their spectral data and comparing them with related references. Among them, compounds <b>1</b> and <b>3</b> exhibited obvious hepatoprotective activities against paracetamol-induced HepG2 cell damage at 10 μM. The results suggested that these compounds could be potential hepatoprotective agents.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"61 6","pages":"1094 - 1098"},"PeriodicalIF":0.9,"publicationDate":"2025-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145847938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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