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Chemistry of Natural Compounds最新文献

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Stilbenes from Stems of Primorsky Grape Variety Alpha and their Antioxidant Activity Primorsky 葡萄品种 Alpha 茎中的芪及其抗氧化活性
IF 0.8 4区 化学
Chemistry of Natural Compounds Pub Date : 2024-08-06 DOI: 10.1007/s10600-024-04414-3
S. A. Fedoreyev, N. P. Mishchenko, D. V. Tarbeeva, E. A. Vasileva, N. D. Pokhilo, V. P. Grigorchuk, A. N. Emelyanov
{"title":"Stilbenes from Stems of Primorsky Grape Variety Alpha and their Antioxidant Activity","authors":"S. A. Fedoreyev, N. P. Mishchenko, D. V. Tarbeeva, E. A. Vasileva, N. D. Pokhilo, V. P. Grigorchuk, A. N. Emelyanov","doi":"10.1007/s10600-024-04414-3","DOIUrl":"10.1007/s10600-024-04414-3","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141933486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New Chalcone Derivative from Persea americana and Its Anti-Tyrosinase Activity 来自 Persea americana 的新查尔酮衍生物及其抗酪氨酸酶活性
IF 0.8 4区 化学
Chemistry of Natural Compounds Pub Date : 2024-08-06 DOI: 10.1007/s10600-024-04399-z
Parinuch Chumkaew, Saysunee Jumrat, Yutthapong Pianroj
{"title":"New Chalcone Derivative from Persea americana and Its Anti-Tyrosinase Activity","authors":"Parinuch Chumkaew,&nbsp;Saysunee Jumrat,&nbsp;Yutthapong Pianroj","doi":"10.1007/s10600-024-04399-z","DOIUrl":"10.1007/s10600-024-04399-z","url":null,"abstract":"<p>Caneeracone A (<b>1</b>), a new chalcone derivative, together with three known compounds (<b>2–4</b>), was isolated from the seeds of <i>Persea americana</i> Mill. (buccaneer avocado). The structures of these compounds were established by spectroscopic methods including 1D and 2D NMR experiments. Compound <b>1</b> exhibited a potent tyrosinase activity with an IC<sub>50</sub> of 38.29 μM.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141933498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antiliver and Colorectal Cancer Activity Metabolites of the Leaves of Michelia crassipes 苁蓉叶中的抗逆转录酶和大肠癌活性代谢物
IF 0.8 4区 化学
Chemistry of Natural Compounds Pub Date : 2024-08-06 DOI: 10.1007/s10600-024-04428-x
S. J. Wang, Y. Z. Dong, S. T. Huang, W. J. Li, H. T. Li, S. L. Liu, C. H. Chuang, C. Y. Chen
{"title":"Antiliver and Colorectal Cancer Activity Metabolites of the Leaves of Michelia crassipes","authors":"S. J. Wang,&nbsp;Y. Z. Dong,&nbsp;S. T. Huang,&nbsp;W. J. Li,&nbsp;H. T. Li,&nbsp;S. L. Liu,&nbsp;C. H. Chuang,&nbsp;C. Y. Chen","doi":"10.1007/s10600-024-04428-x","DOIUrl":"10.1007/s10600-024-04428-x","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142410079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
(±)-Mucroniferal D: a Pair of New Phenolic Enantiomers from Corydalis mucronifera (±)-Mucroniferal D：来自堇菜的一对新酚类对映体
IF 0.8 4区 化学
Chemistry of Natural Compounds Pub Date : 2024-08-06 DOI: 10.1007/s10600-024-04401-8
Xupei Men, Jie Song, Xiaomei Song, Xiangdong Qin, Du-Qiang Luo, Jun Zhang
{"title":"(±)-Mucroniferal D: a Pair of New Phenolic Enantiomers from Corydalis mucronifera","authors":"Xupei Men,&nbsp;Jie Song,&nbsp;Xiaomei Song,&nbsp;Xiangdong Qin,&nbsp;Du-Qiang Luo,&nbsp;Jun Zhang","doi":"10.1007/s10600-024-04401-8","DOIUrl":"10.1007/s10600-024-04401-8","url":null,"abstract":"<p>Chemical investigation of <i>Corydalis mucronifera</i> has resulted in the isolation and identification of a pair of new enantiomeric phenolic constituents (±)-mucroniferal D (<b>1</b>) and five known ones (<b>2–6</b>). Their structures were elucidated based on extensive spectroscopic data analysis of MS, 1D and 2D NMR, and their absolute configurations were confirmed by comparison of the optical rotation data. Compounds <b>1–6</b> showed moderate cytotoxic activities against MCF-7, MGC-803, and HeLa cell lines with the IC<sub>50</sub> values ranging from 22.61–98.30 μg·mL<sup>–1</sup>.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141933613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preparation and Physicochemical Properties of Collagen for Wound Dressings 用于伤口敷料的胶原蛋白的制备和理化特性
IF 0.8 4区 化学
Chemistry of Natural Compounds Pub Date : 2024-08-06 DOI: 10.1007/s10600-024-04412-5
N. E. Tseomashko, A. N. Tretyakova, A. Yu. Vasil′kov
{"title":"Preparation and Physicochemical Properties of Collagen for Wound Dressings","authors":"N. E. Tseomashko,&nbsp;A. N. Tretyakova,&nbsp;A. Yu. Vasil′kov","doi":"10.1007/s10600-024-04412-5","DOIUrl":"10.1007/s10600-024-04412-5","url":null,"abstract":"<p>Type I collagen was obtained in gel-like form by enzymatic-acidic extraction from cattle tail tendons and was polymerized at room temperature in ammonia vapor to form a transparent film 60.47–64.9 μm thick with good adhesive properties of 11.6–12.4 kPa and tensile strength 559.5–600.5 kPa. The dependence of the film adhesive properties on its ability to stimulate regenerative processes in tissues was found. The collagen was characterized by X-ray photoelectron spectroscopy. The C 1s spectrum showed peaks for C–C/C–H, C–O–C/C–OH, O=C–N, and O=C–OH groups; the N 1s spectrum for C–NH<sub>2</sub>, O=C–N, and C–NH<sub>3</sub><sup>+</sup> groups.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141933484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
2-Oxomethylcytisine Derivatives with Potential Anti-Coronavirus Activity 具有潜在抗冠状病毒活性的 2-氧甲基胞嘧啶衍生物
IF 0.8 4区 化学
Chemistry of Natural Compounds Pub Date : 2024-08-06 DOI: 10.1007/s10600-024-04411-6
A. V. Koval′skaya, A. N. Lobov, D. O. Tsypyshev, Ch.V. Lin, I. P. Tsypysheva
{"title":"2-Oxomethylcytisine Derivatives with Potential Anti-Coronavirus Activity","authors":"A. V. Koval′skaya,&nbsp;A. N. Lobov,&nbsp;D. O. Tsypyshev,&nbsp;Ch.V. Lin,&nbsp;I. P. Tsypysheva","doi":"10.1007/s10600-024-04411-6","DOIUrl":"10.1007/s10600-024-04411-6","url":null,"abstract":"<p>Diels−Alder <i>β</i>-endo adducts of 2-oxomethylcytisine and <i>N</i>-substituted maleimides were synthesized. Their ability to interact with the 6LU7 active site of SARS-CoV-2 main protease Mpro was evaluated <i>in silico</i>. The tested compounds included the potential anti-coronavirus agent (3aR,4S,8S,12S,12aS,12bR)-2-(3-methoxyphenyl)-10-methyl-3a,7,8,9,10,12b-hexahydro-1H-4,12a-etheno-8,12-methanopyrrolo[3′,4′:3,4]pyrido[1,2-a][1,5]diazocine-1,3,5,11(2H,4H,12H)-tetrone, which had calculated characteristics exceeding those of the reference ligand tideglusib.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141933483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A New Cyclic Peptide from Betel Nut Endophytic Fungus Alternaria sp. RW-AL 来自槟榔内生真菌 Alternaria sp.
IF 0.8 4区 化学
Chemistry of Natural Compounds Pub Date : 2024-08-06 DOI: 10.1007/s10600-024-04413-4
Wu Ruan, Qing-Yun Ma, Jiao-Cen Guo, Qing-Yi Xie, Li Yang, Hao-Fu Dai, You-Geng Wu, You-Xing Zhao
{"title":"A New Cyclic Peptide from Betel Nut Endophytic Fungus Alternaria sp. RW-AL","authors":"Wu Ruan,&nbsp;Qing-Yun Ma,&nbsp;Jiao-Cen Guo,&nbsp;Qing-Yi Xie,&nbsp;Li Yang,&nbsp;Hao-Fu Dai,&nbsp;You-Geng Wu,&nbsp;You-Xing Zhao","doi":"10.1007/s10600-024-04413-4","DOIUrl":"10.1007/s10600-024-04413-4","url":null,"abstract":"<p>A new cyclic peptide alternarin A (<b>1</b>), along with seven known compounds, alternariol (<b>2</b>), sulfated derivative of alternariol (<b>3</b>), alternariol methyl ether (<b>4</b>), altenuene (<b>5</b>), 2,5-dimethyl-7-hydroxychromone (<b>6</b>), diaporthein A (<b>7</b>), isopterocarpolone (<b>8</b>), were isolated from the betel nut endophytic fungus <i>Alternaria</i> sp. RW-AL. The structure of <b>1</b> was elucidated by 1D and 2D NMR spectra as well as HR-ESI-MS analysis. Compounds <b>1</b>, <b>4</b>, and <b>5</b> showed definite antibacterial activities against <i>Staphylococcus aureus</i> ATCC 6538 and <i>Bacillus subtilis</i> ATCC 6633.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141933559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Flavonoids with Leucopoeisis Activity from Extract of Astragalus bungeanus 黄芪提取物中具有白果活性的黄酮类化合物
IF 0.8 4区 化学
Chemistry of Natural Compounds Pub Date : 2024-08-06 DOI: 10.1007/s10600-024-04425-0
N. Sh. Kavtaradze, M. Z. Getia
{"title":"Flavonoids with Leucopoeisis Activity from Extract of Astragalus bungeanus","authors":"N. Sh. Kavtaradze,&nbsp;M. Z. Getia","doi":"10.1007/s10600-024-04425-0","DOIUrl":"10.1007/s10600-024-04425-0","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142410176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phenylpropanoids with Anti-Inflammatory Effects from the Roots of Platycodon grandiflorus 桔梗根中具有抗炎作用的苯丙酸类化合物
IF 0.8 4区 化学
Chemistry of Natural Compounds Pub Date : 2024-08-06 DOI: 10.1007/s10600-024-04402-7
Yang Yu, Lan Ding, Ren-Nai Yang, Liang-Ping Zha, Ju-Tao Wang, Shuang-Ying Gui
{"title":"Phenylpropanoids with Anti-Inflammatory Effects from the Roots of Platycodon grandiflorus","authors":"Yang Yu,&nbsp;Lan Ding,&nbsp;Ren-Nai Yang,&nbsp;Liang-Ping Zha,&nbsp;Ju-Tao Wang,&nbsp;Shuang-Ying Gui","doi":"10.1007/s10600-024-04402-7","DOIUrl":"10.1007/s10600-024-04402-7","url":null,"abstract":"<p>Two new phenylpropanoids, plagnans (<b>1</b>) and plaganoid (<b>2</b>), along with five known phenylpropanoids, including an enantiomeric mixture (compound <b>3</b>) were isolated from the roots of <i>Platycodon grandiflorus.</i> Meanwhile, their structures were elucidated by analyzing the spectroscopic data, including NMR, HR-ESI-MS, ECD (ICD), and X-ray analysis. Although all isolates were evaluated for their anti-inflammatory activities, and of them exhibited moderate activities, with IC<sub>50</sub> values of around 27.5 μM.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141933485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metabolites from Michelia compressa var. lanyuensis with Antioxidant Activity 具有抗氧化活性的扁柏变种代谢物
IF 0.8 4区 化学
Chemistry of Natural Compounds Pub Date : 2024-08-06 DOI: 10.1007/s10600-024-04418-z
C. T. Chang, W. J. Li, H. T. Li, S. L. Liu, C. Y. Chen
{"title":"Metabolites from Michelia compressa var. lanyuensis with Antioxidant Activity","authors":"C. T. Chang,&nbsp;W. J. Li,&nbsp;H. T. Li,&nbsp;S. L. Liu,&nbsp;C. Y. Chen","doi":"10.1007/s10600-024-04418-z","DOIUrl":"10.1007/s10600-024-04418-z","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141933494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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