Tomography最新文献_第8页

Novel Deep CNNs Explore Regions, Boundaries, and Residual Learning for COVID-19 Infection Analysis in Lung CT. 新型深度 CNN 探索区域、边界和残余学习，用于肺部 CT 中的 COVID-19 感染分析。

IF 2.2 4区医学

Tomography Pub Date : 2024-08-03 DOI: 10.3390/tomography10080091

Bader Khalid Alshemaimri

{"title":"Novel Deep CNNs Explore Regions, Boundaries, and Residual Learning for COVID-19 Infection Analysis in Lung CT.","authors":"Bader Khalid Alshemaimri","doi":"10.3390/tomography10080091","DOIUrl":"10.3390/tomography10080091","url":null,"abstract":"COVID-19 poses a global health crisis, necessitating precise diagnostic methods for timely containment. However, accurately delineating COVID-19-affected regions in lung CT scans is challenging due to contrast variations and significant texture diversity. In this regard, this study introduces a novel two-stage classification and segmentation CNN approach for COVID-19 lung radiological pattern analysis. A novel Residual-BRNet is developed to integrate boundary and regional operations with residual learning, capturing key COVID-19 radiological homogeneous regions, texture variations, and structural contrast patterns in the classification stage. Subsequently, infectious CT images undergo lesion segmentation using the newly proposed RESeg segmentation CNN in the second stage. The RESeg leverages both average and max-pooling implementations to simultaneously learn region homogeneity and boundary-related patterns. Furthermore, novel pixel attention (PA) blocks are integrated into RESeg to effectively address mildly COVID-19-infected regions. The evaluation of the proposed Residual-BRNet CNN in the classification stage demonstrates promising performance metrics, achieving an accuracy of 97.97%, F1-score of 98.01%, sensitivity of 98.42%, and MCC of 96.81%. Meanwhile, PA-RESeg in the segmentation phase achieves an optimal segmentation performance with an IoU score of 98.43% and a dice similarity score of 95.96% of the lesion region. The framework's effectiveness in detecting and segmenting COVID-19 lesions highlights its potential for clinical applications.","PeriodicalId":51330,"journal":{"name":"Tomography","volume":"10 8","pages":"1205-1221"},"PeriodicalIF":2.2,"publicationDate":"2024-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11359787/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142082480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Review of 3D Modalities Used for the Diagnosis of Scoliosis. 用于诊断脊柱侧弯的 3D 模式综述。

IF 2.2 4区医学

Tomography Pub Date : 2024-08-02 DOI: 10.3390/tomography10080090

Sampath Kumar, Bhaskar Awadhiya, Rahul Ratnakumar, Ananthakrishna Thalengala, Anu Shaju Areeckal, Yashwanth Nanjappa

{"title":"A Review of 3D Modalities Used for the Diagnosis of Scoliosis.","authors":"Sampath Kumar, Bhaskar Awadhiya, Rahul Ratnakumar, Ananthakrishna Thalengala, Anu Shaju Areeckal, Yashwanth Nanjappa","doi":"10.3390/tomography10080090","DOIUrl":"10.3390/tomography10080090","url":null,"abstract":"Spine radiographs in the standing position are the recommended standard for diagnosing idiopathic scoliosis. Though the deformity exists in 3D, its diagnosis is currently carried out with the help of 2D radiographs due to the unavailability of an efficient, low-cost 3D alternative. Computed tomography (CT) and magnetic resonance imaging (MRI) are not suitable in this case, as they are obtained in the supine position. Research on 3D modelling of scoliotic spine began with multiplanar radiographs and later moved on to biplanar radiographs and finally a single radiograph. Nonetheless, modern advances in diagnostic imaging have the potential to preserve image quality and decrease radiation exposure. They include the DIERS formetric scanner system, the EOS imaging system, and ultrasonography. This review article briefly explains the technology behind each of these methods. They are compared with the standard imaging techniques. The DIERS system and ultrasonography are radiation free but have limitations with respect to the quality of the 3D model obtained. There is a need for 3D imaging technology with less or zero radiation exposure and that can produce a quality 3D model for diseases like adolescent idiopathic scoliosis. Accurate 3D models are crucial in clinical practice for diagnosis, planning surgery, patient follow-up examinations, biomechanical applications, and computer-assisted surgery.","PeriodicalId":51330,"journal":{"name":"Tomography","volume":"10 8","pages":"1192-1204"},"PeriodicalIF":2.2,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11360202/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142082472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Novel and Reliable Pixel Response Correction Method (DAC-Shifting) for Spectral Photon-Counting CT Imaging. 用于光谱光子计数 CT 成像的新颖可靠的像素响应校正方法（DAC-Shifting）。

IF 2.2 4区医学

Tomography Pub Date : 2024-07-22 DOI: 10.3390/tomography10070089

Navrit Johan Singh Bal, Imaiyan Chitra Ragupathy, Trine Tramm, Jasper Nijkamp

{"title":"A Novel and Reliable Pixel Response Correction Method (DAC-Shifting) for Spectral Photon-Counting CT Imaging.","authors":"Navrit Johan Singh Bal, Imaiyan Chitra Ragupathy, Trine Tramm, Jasper Nijkamp","doi":"10.3390/tomography10070089","DOIUrl":"10.3390/tomography10070089","url":null,"abstract":"Spectral photon-counting cone-beam computed tomography (CT) imaging is challenged by individual pixel response behaviours, which lead to noisy projection images and subsequent image artefacts like rings. Existing methods to correct for this either use calibration measurements, like signal-to-thickness calibration (STC), or perform a post-processing ring artefact correction of sinogram data or scan reconstructions without taking the pixel response explicitly into account. Here, we present a novel post-processing method (digital-to-analogue converter (DAC)-shifting) which explicitly measures the current pixel response using flat-field images and subsequently corrects the projection data. The DAC-shifting method was evaluated using a repeat series of the spectral photon-counting imaging (Medipix3) of a phantom with different density inserts and iodine K-edge imaging. The method was also compared against polymethyl methacrylate (PMMA)-based STC. The DAC-shifting method was shown to be effective in correcting individual pixel responses and was robust against detector instability; it led to a 47.4% average reduction in CT-number variation in homogeneous materials, with a range of 40.7-55.6%. On the contrary, the STC correction showed varying results; a 13.7% average reduction in CT-number variation, ranging from a 43.7% increase to a 45.5% reduction. In K-edge imaging, DAC-shifting provides a sharper attenuation peak and more uniform CT values, which are expected to benefit iodine concentration quantifications.","PeriodicalId":51330,"journal":{"name":"Tomography","volume":"10 7","pages":"1168-1191"},"PeriodicalIF":2.2,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11281142/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141762510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Incidence and Characteristics of Pelvic-Origin Varicosities in Patients with Complex Varices Evaluated by Ultrasonography. 通过超声波检查评估复杂静脉曲张患者盆腔源性静脉曲张的发病率和特征。

IF 2.2 4区医学

Tomography Pub Date : 2024-07-19 DOI: 10.3390/tomography10070088

Kwon Cheol Yoo, Hyung Sub Park, Chang Sik Shin, Taeseung Lee

{"title":"The Incidence and Characteristics of Pelvic-Origin Varicosities in Patients with Complex Varices Evaluated by Ultrasonography.","authors":"Kwon Cheol Yoo, Hyung Sub Park, Chang Sik Shin, Taeseung Lee","doi":"10.3390/tomography10070088","DOIUrl":"10.3390/tomography10070088","url":null,"abstract":"Objective: The purpose of this study was to evaluate the incidence of gonadal vein refluxes associated with lower-extremity varicose veins with Doppler ultrasonography (DUS).Method: A total of 6279 patients with venous disease-related symptoms of the lower extremity were evaluated with DUS in the vascular lab. Gonadal vein reflux using abdominal ultrasound was further evaluated in patients with unusual varices, defined as varices in the inguinal, inner or upper thigh and the vulvar area without refluxes in the saphenofemoral junction (SPJ). Those patients who showed gonadal vein reflux were diagnosed as having pelvic-origin varicosity.Results: Unusual varices were found in a total of 237 patients (3.8%), and of these patients, pelvic-origin varicosity was discovered with transabdominal ultrasound in 156 (65.8%). A total of 66.7% (n = 38/57) of unusual varix patients with pelvic pain had gonadal vein reflux. The measurement of gonadal vein diameter was larger in ultrasonography than CT scans (8.835 vs. 8.81, p < 0.001). Two patients with severe symptoms but no obstructive venous diseases were treated with gonadal vein embolization.Conclusion: The incidence of pelvic-origin varicosities was 2.5% (n = 156/6279). However, more than half of the patients with unusual varices had gonadal vein reflux and 24.4% of these patients also presented with pelvic pain. The evaluation of pelvic-origin varicosities should be performed in patients who present with unusual forms of varices of the lower extremity.","PeriodicalId":51330,"journal":{"name":"Tomography","volume":"10 7","pages":"1159-1167"},"PeriodicalIF":2.2,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11280516/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141762515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pericardial Calcification: An Uncommon Case with Intraventricular Extension. 心包钙化：心室内扩展的罕见病例

IF 2.2 4区医学

Tomography Pub Date : 2024-06-29 DOI: 10.3390/tomography10070076

Miguel Santaularia-Tomas, Ely Sanchez-Felix, Kassandra Santos-Zaldivar, Allison Grosjean-Alvarez, Nina Mendez-Dominguez

{"title":"Pericardial Calcification: An Uncommon Case with Intraventricular Extension.","authors":"Miguel Santaularia-Tomas, Ely Sanchez-Felix, Kassandra Santos-Zaldivar, Allison Grosjean-Alvarez, Nina Mendez-Dominguez","doi":"10.3390/tomography10070076","DOIUrl":"10.3390/tomography10070076","url":null,"abstract":"An 80-year-old man presented to the cardiology outpatient clinic due to shortness of breath. His past medical history included alcohol intake, hypertension, inferior wall myocardial infarction (five years ago), an ischemic stroke, and permanent atrial fibrillation (diagnosed three years before the current examination). A physical exam revealed a decreased intensity of S1 and S2, irregular rate and rhythm, and no murmurs nor friction rub. X-rays, Computed Tomography, and echocardiography exhibited pericardial calcification, involving mostly the inferior wall and protruding into the left ventricle. A diagnosis of constrictive pericarditis due to pericardial calcification was established and considered idiopathic. Even when it may be related to ischemic heart disease, post-infarction pericarditis could explain how the calcification extended to adjacent territory perfused by the circumflex coronary artery. Combined imaging studies were crucial not only for identifying calcium deposits in the pericardium but also in assessing a patient inherently prone to co-existing and exacerbating conditions. Even though pericardiectomy allows for removal of the clinical manifestations of congestive pericarditis in the most symptomatic patients with pericardial calcification, among patients like ours, with tolerable symptoms, cardiologists should discuss the therapeutic options considering the patient's choices, potentially including a rehabilitation plan as part of non-pharmacological management.","PeriodicalId":51330,"journal":{"name":"Tomography","volume":"10 7","pages":"1024-1030"},"PeriodicalIF":2.2,"publicationDate":"2024-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11281272/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141762513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fat Fraction Extracted from Whole-Body Magnetic Resonance (WB-MR) in Bone Metastatic Prostate Cancer: Intra- and Inter-Reader Agreement of Single-Slice and Volumetric Measurements. 从全身磁共振（WB-MR）中提取骨转移前列腺癌患者的脂肪比例：单片和体积测量的读片机内部和读片机之间的一致性。

IF 2.2 4区医学

Tomography Pub Date : 2024-06-28 DOI: 10.3390/tomography10070075

Giorgio Maria Agazzi, Nunzia Di Meo, Paolo Rondi, Chiara Saeli, Alberto Dalla Volta, Marika Vezzoli, Alfredo Berruti, Andrea Borghesi, Roberto Maroldi, Marco Ravanelli, Davide Farina

{"title":"Fat Fraction Extracted from Whole-Body Magnetic Resonance (WB-MR) in Bone Metastatic Prostate Cancer: Intra- and Inter-Reader Agreement of Single-Slice and Volumetric Measurements.","authors":"Giorgio Maria Agazzi, Nunzia Di Meo, Paolo Rondi, Chiara Saeli, Alberto Dalla Volta, Marika Vezzoli, Alfredo Berruti, Andrea Borghesi, Roberto Maroldi, Marco Ravanelli, Davide Farina","doi":"10.3390/tomography10070075","DOIUrl":"10.3390/tomography10070075","url":null,"abstract":"Background: This study evaluates the repeatability and reproducibility of fat-fraction percentage (FF%) in whole-body magnetic resonance imaging (WB-MRI) of prostate cancer patients with bone metastatic hormone naive disease.Methods: Patients were selected from the database of a prospective phase-II trial. The treatment response was assessed using the METastasis Reporting and Data System for Prostate (MET-RADS-P). Two operators identified a Small Active Lesion (SAL, <10 mm) and a Large Active Lesion (LAL, ≥10 mm) per patient, performing manual segmentation of lesion volume and the largest cross-sectional area. Measurements were repeated by one operator after two weeks. Intra- and inter-reader agreements were assessed via Interclass Correlation Coefficient (ICC) on first-order radiomics features.Results: Intra-reader ICC showed high repeatability for both SAL and LAL in a single slice (SS) and volumetric (VS) measurements with values ranging from 0.897 to 0.971. Inter-reader ICC ranged from 0.641 to 0.883, indicating moderate to good reproducibility. Spearman's rho analysis confirmed a strong correlation between SS and VS measurements for SAL (0.817) and a moderate correlation for LAL (0.649). Both intra- and inter-rater agreement exceeded 0.75 for multiple first-order features across lesion sizes.Conclusion: This study suggests that FF% measurements are reproducible, particularly for larger lesions in both SS and VS assessments.","PeriodicalId":51330,"journal":{"name":"Tomography","volume":"10 7","pages":"1014-1023"},"PeriodicalIF":2.2,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11280977/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141762512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultra-High Contrast MRI: The Whiteout Sign Shown with Divided Subtracted Inversion Recovery (dSIR) Sequences in Post-Insult Leukoencephalopathy Syndromes (PILS). 超高对比 MRI：用分割减影反转恢复 (dSIR) 序列显示的感染后白质脑病综合征 (PILS) 的 "白化征"。

IF 2.2 4区医学

Tomography Pub Date : 2024-06-26 DOI: 10.3390/tomography10070074

Paul Condron, Daniel M Cornfeld, Miriam Scadeng, Tracy R Melzer, Gil Newburn, Mark Bydder, Eryn E Kwon, Joshua P McGeown, Geoffrey G Handsfield, Taylor Emsden, Maryam Tayebi, Samantha J Holdsworth, Graeme M Bydder

{"title":"Ultra-High Contrast MRI: The Whiteout Sign Shown with Divided Subtracted Inversion Recovery (dSIR) Sequences in Post-Insult Leukoencephalopathy Syndromes (PILS).","authors":"Paul Condron, Daniel M Cornfeld, Miriam Scadeng, Tracy R Melzer, Gil Newburn, Mark Bydder, Eryn E Kwon, Joshua P McGeown, Geoffrey G Handsfield, Taylor Emsden, Maryam Tayebi, Samantha J Holdsworth, Graeme M Bydder","doi":"10.3390/tomography10070074","DOIUrl":"10.3390/tomography10070074","url":null,"abstract":"Ultra-high contrast (UHC) MRI describes forms of MRI in which little or no contrast is seen on conventional MRI images but very high contrast is seen with UHC techniques. One of these techniques uses the divided subtracted inversion recovery (dSIR) sequence, which, in modelling studies, can produce ten times the contrast of conventional inversion recovery (IR) sequences. When used in cases of mild traumatic brain injury (mTBI), the dSIR sequence frequently shows extensive abnormalities in white matter that appears normal when imaged with conventional T2-fluid-attenuated IR (T2-FLAIR) sequences. The changes are bilateral and symmetrical in white matter of the cerebral and cerebellar hemispheres. They partially spare the anterior and posterior central corpus callosum and peripheral white matter of the cerebral hemispheres and are described as the whiteout sign. In addition to mTBI, the whiteout sign has also been seen in methamphetamine use disorder and Grinker's myelinopathy (delayed post-hypoxic leukoencephalopathy) in the absence of abnormalities on T2-FLAIR images, and is a central component of post-insult leukoencephalopathy syndromes. This paper describes the concept of ultra-high contrast MRI, the whiteout sign, the theory underlying the use of dSIR sequences and post-insult leukoencephalopathy syndromes.","PeriodicalId":51330,"journal":{"name":"Tomography","volume":"10 7","pages":"983-1013"},"PeriodicalIF":2.2,"publicationDate":"2024-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11280826/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141762516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application of Diffusion Kurtosis Imaging and Blood Oxygen Level-Dependent Magnetic Resonance Imaging in Kidney Injury Associated with ANCA-Associated Vasculitis. 弥散峰度成像和血氧水平依赖性磁共振成像在ANCA相关性血管炎肾损伤中的应用

IF 2.2 4区医学

Tomography Pub Date : 2024-06-25 DOI: 10.3390/tomography10070073

Wenhui Yu, Weijie Yan, Jing Yi, Lu Cheng, Peiyi Luo, Jiayu Sun, Shenju Gou, Ping Fu

{"title":"Application of Diffusion Kurtosis Imaging and Blood Oxygen Level-Dependent Magnetic Resonance Imaging in Kidney Injury Associated with ANCA-Associated Vasculitis.","authors":"Wenhui Yu, Weijie Yan, Jing Yi, Lu Cheng, Peiyi Luo, Jiayu Sun, Shenju Gou, Ping Fu","doi":"10.3390/tomography10070073","DOIUrl":"10.3390/tomography10070073","url":null,"abstract":"Objective: Functional magnetic resonance imaging (fMRI) has been applied to assess the microstructure of the kidney. However, it is not clear whether fMRI could be used in the field of kidney injury in patients with Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV).Methods: This study included 20 patients with AAV. Diffusion kurtosis imaging (DKI) and blood oxygen level-dependent (BOLD) scanning of the kidneys were performed in AAV patients and healthy controls. The mean kurtosis (MK), mean diffusivity (MD), and fractional anisotropy (FA) parameters of DKI, the R2* parameter of BOLD, and clinical data were further analyzed.Results: In AAV patients, the cortex exhibited lower MD but higher R2* values compared to the healthy controls. Medullary MK values were elevated in AAV patients. Renal medullary MK values showed a positive correlation with serum creatinine levels and negative correlations with hemoglobin levels and estimated glomerular filtration rate. To assess renal injury in AAV patients, AUC values for MK, MD, FA, and R2* in the cortex were 0.66, 0.67, 0.57, and 0.55, respectively, and those in the medulla were 0.81, 0.77, 0.61, and 0.53, respectively.Conclusions: Significant differences in DKI and BOLD MRI parameters were observed between AAV patients with kidney injuries and the healthy controls. The medullary MK value in DKI may be a noninvasive marker for assessing the severity of kidney injury in AAV patients.","PeriodicalId":51330,"journal":{"name":"Tomography","volume":"10 7","pages":"970-982"},"PeriodicalIF":2.2,"publicationDate":"2024-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11280752/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141762511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantitative and Compositional MRI of the Articular Cartilage: A Narrative Review. 关节软骨的定量和成分 MRI：叙述性综述。

IF 2.2 4区医学

Tomography Pub Date : 2024-06-24 DOI: 10.3390/tomography10070072

Domenico Albano, Umberto Viglino, Francesco Esposito, Aldo Rizzo, Carmelo Messina, Salvatore Gitto, Stefano Fusco, Francesca Serpi, Benedikt Kamp, Anja Müller-Lutz, Riccardo D'Ambrosi, Luca Maria Sconfienza, Philipp Sewerin

{"title":"Quantitative and Compositional MRI of the Articular Cartilage: A Narrative Review.","authors":"Domenico Albano, Umberto Viglino, Francesco Esposito, Aldo Rizzo, Carmelo Messina, Salvatore Gitto, Stefano Fusco, Francesca Serpi, Benedikt Kamp, Anja Müller-Lutz, Riccardo D'Ambrosi, Luca Maria Sconfienza, Philipp Sewerin","doi":"10.3390/tomography10070072","DOIUrl":"10.3390/tomography10070072","url":null,"abstract":"This review examines the latest advancements in compositional and quantitative cartilage MRI techniques, addressing both their potential and challenges. The integration of these advancements promises to improve disease detection, treatment monitoring, and overall patient care. We want to highlight the pivotal task of translating these techniques into widespread clinical use, the transition of cartilage MRI from technical validation to clinical application, emphasizing its critical role in identifying early signs of degenerative and inflammatory joint diseases. Recognizing these changes early may enable informed treatment decisions, thereby facilitating personalized medicine approaches. The evolving landscape of cartilage MRI underscores its increasing importance in clinical practice, offering valuable insights for patient management and therapeutic interventions. This review aims to discuss the old evidence and new insights about the evaluation of articular cartilage through MRI, with an update on the most recent literature published on novel quantitative sequences.","PeriodicalId":51330,"journal":{"name":"Tomography","volume":"10 7","pages":"949-969"},"PeriodicalIF":2.2,"publicationDate":"2024-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11280587/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141762514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Literature Review on the Relative Diagnostic Accuracy of Chest CT Scans versus RT-PCR Testing for COVID-19 Diagnosis. 胸部 CT 扫描与 RT-PCR 检测对 COVID-19 诊断的相对诊断准确性文献综述。

IF 2.2 4区医学

Tomography Pub Date : 2024-06-14 DOI: 10.3390/tomography10060071

Hafez Al-Momani

{"title":"A Literature Review on the Relative Diagnostic Accuracy of Chest CT Scans versus RT-PCR Testing for COVID-19 Diagnosis.","authors":"Hafez Al-Momani","doi":"10.3390/tomography10060071","DOIUrl":"10.3390/tomography10060071","url":null,"abstract":"Background: Reverse transcription polymerase chain reaction (RT-PCR) is the main technique used to identify COVID-19 from respiratory samples. It has been suggested in several articles that chest CTs could offer a possible alternate diagnostic tool for COVID-19; however, no professional medical body recommends using chest CTs as an early COVID-19 detection modality. This literature review examines the use of CT scans as a diagnostic tool for COVID-19.Method: A comprehensive search of research works published in peer-reviewed journals was carried out utilizing precisely stated criteria. The search was limited to English-language publications, and studies of COVID-19-positive patients diagnosed using both chest CT scans and RT-PCR tests were sought. For this review, four databases were consulted: these were the Cochrane and ScienceDirect catalogs, and the CINAHL and Medline databases made available by EBSCOhost.Findings: In total, 285 possibly pertinent studies were found during an initial search. After applying inclusion and exclusion criteria, six studies remained for analysis. According to the included studies, chest CT scans were shown to have a 44 to 98% sensitivity and 25 to 96% specificity in terms of COVID-19 diagnosis. However, methodological limitations were identified in all studies included in this review.Conclusion: RT-PCR is still the suggested first-line diagnostic technique for COVID-19; while chest CT is adequate for use in symptomatic patients, it is not a sufficiently robust diagnostic tool for the primary screening of COVID-19.","PeriodicalId":51330,"journal":{"name":"Tomography","volume":"10 6","pages":"935-948"},"PeriodicalIF":2.2,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11209112/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141452075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0