Cognitive NeuropsychiatryPub Date : 2024-11-01Epub Date: 2025-01-31DOI: 10.1080/13546805.2025.2452259
Bruce Tamilson, Norman Poole, Niruj Agrawal
{"title":"The co-occurrence of functional neurological disorder and autism spectrum disorder: a systematic literature review and meta-analysis.","authors":"Bruce Tamilson, Norman Poole, Niruj Agrawal","doi":"10.1080/13546805.2025.2452259","DOIUrl":"10.1080/13546805.2025.2452259","url":null,"abstract":"<p><strong>Background: </strong>Recent studies reveal increasing interest in the link between Autism Spectrum Disorder (ASD) and Functional Neurological Disorder (FND), prompting a systematic review and meta-analysis of their co-occurrence.</p><p><strong>Method: </strong>The review covered a comprehensive literature search across multiple databases up to November 2024, focusing on peer-reviewed studies of ASD and FND co-occurrence. Twenty-four studies qualified for inclusion.</p><p><strong>Results: </strong>The study included 11,324 participants, predominantly female (73.4%). It estimated the proportion of ASD in FND populations to be 0.10 (95% CI: 0.07-0.15), with significant heterogeneity (I² = 97%, <i>p</i> < 0.01). Subgroup analysis showed variation among different age groups and diagnoses. The proportion of ASD was 0.09 in adults and 0.10 in children with FND, 0.15 in adults and 0.19 in children with Functional Tic-Like Behaviours (FTLB), and 0.07 in children with Functional Seizures (FS).</p><p><strong>Conclusion: </strong>Many studies have reported the co-occurrence of ASD in FND, suggesting a higher-than-expected rate of 10%. Emerging themes exploring the overlapping determinants of FND and ASD, are discussed. However, the significance of this correlation and the overlapping determinants that might explain it, require further research due to the heterogeneity in methodologies, settings, conditions studied and findings. The presence of publication bias warrants cautious interpretation of the results.</p>","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":" ","pages":"358-385"},"PeriodicalIF":1.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143069260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sanne Roels, Sander Begeer, Anke M. Scheeren, Jan-Willem van Prooijen
{"title":"Conspiracy mentality in autistic and non-autistic individuals","authors":"Sanne Roels, Sander Begeer, Anke M. Scheeren, Jan-Willem van Prooijen","doi":"10.1080/13546805.2024.2399505","DOIUrl":"https://doi.org/10.1080/13546805.2024.2399505","url":null,"abstract":"Belief in conspiracy theories has emerged across times and cultures. While previous accounts attributed conspiracy beliefs to mental health conditions, accumulating research suggests that conspirac...","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":"34 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142184117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cognitive NeuropsychiatryPub Date : 2024-07-01Epub Date: 2024-11-07DOI: 10.1080/13546805.2024.2422620
Nadine Dijkstra, Laura Convertino, Sarah Garfinkel
{"title":"How disrupted interoception could lead to disturbances in perceptual reality monitoring.","authors":"Nadine Dijkstra, Laura Convertino, Sarah Garfinkel","doi":"10.1080/13546805.2024.2422620","DOIUrl":"10.1080/13546805.2024.2422620","url":null,"abstract":"","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":" ","pages":"219-227"},"PeriodicalIF":1.5,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142605087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cognitive NeuropsychiatryPub Date : 2024-07-01Epub Date: 2024-11-05DOI: 10.1080/13546805.2024.2425322
Andrea Wong, Frank D Baughman, Barbara A Mullan, Karen Heslop, Evan Dauer, Darren Haywood
{"title":"Can neurocognitive performance account for dimensional paranoid ideation?","authors":"Andrea Wong, Frank D Baughman, Barbara A Mullan, Karen Heslop, Evan Dauer, Darren Haywood","doi":"10.1080/13546805.2024.2425322","DOIUrl":"10.1080/13546805.2024.2425322","url":null,"abstract":"<p><strong>Objective: </strong>Paranoid ideation underlies numerous psychological disorders and has debilitating effects on daily life. Deficits in neurocognition are highlighted as a contributing factor to paranoid-related disorders, but the impact on the symptom-level experience of paranoid ideation is unclear. This study aimed to employ a dimensional approach to understand the association between neurocognition and the severity and presence of paranoid ideation.</p><p><strong>Methods: </strong>400 participants, representative of the general population of the USA, completed an online questionnaire consisting of the Brief Symptom Inventory-53, and demographic and clinical questions. The participants then completed four computerised neurocognitive tasks measuring working memory, shifting, inhibition, and speed of processing.</p><p><strong>Results: </strong>Speed of processing accounted for unique variance in the severity of paranoid ideation with a small effect size, after controlling for covariates. Working memory, shifting, and inhibition could not uniquely or collectively, account for paranoid ideation. Neurocognitive performance could not distinguish between individuals with and without paranoid ideation experiences.</p><p><strong>Conclusions: </strong>This research supports the body of literature that speed of information processing may be a key feature of paranoid ideation. Future research should employ non-linear dynamic methods to better understand the potential interactions between neurocognitive components and how this may relate to paranoid ideation.</p>","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":" ","pages":"242-255"},"PeriodicalIF":1.5,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cognitive NeuropsychiatryPub Date : 2024-07-01Epub Date: 2024-12-24DOI: 10.1080/13546805.2024.2443576
Neophytos Georgiou, Ryan P Balzan, Paul Delfabbro, Robyn Young
{"title":"People with autistic traits are more likely to engage with misinformation and conspiracy theories in a simulated social media context.","authors":"Neophytos Georgiou, Ryan P Balzan, Paul Delfabbro, Robyn Young","doi":"10.1080/13546805.2024.2443576","DOIUrl":"10.1080/13546805.2024.2443576","url":null,"abstract":"<p><strong>Background: </strong>People with higher levels of autistic traits are shown to be more likely to endorse conspiracy theories and misinformation on traditional methods of measurement (e.g., self-report). However, such research has been limited by the lack of a naturalistic measure of misinformation and conspiracy theory endorsement that resembles social media platforms.</p><p><strong>Method: </strong>This study included measures of autistic traits, performance measures of critical reasoning and other notable covariates, to assess how participants performed in a simulated social media environment via the Misinformation Game, and whether they actively engaged with misinformation content.</p><p><strong>Results: </strong>The results confirmed via a multiple mediation model (i.e., path analysis) that particular autistic traits, such as a lower ability to engage with imagination and higher attention to detail, were directly associated with false post engagement on the Misinformation Game and conspiracy theories. The relationship between autistic traits, conspiracy theories and misinformation was also partially mediated by scientific reasoning skills.</p><p><strong>Limitations: </strong>This study was partially based on self-report methodology and did not use an entirely clinical sample.</p><p><strong>Conclusion: </strong>There are particular autistic traits associated with the endorsement of misinformation and conspiracy theories which illustrate tendencies that could be focussed upon in future research to how best avoid misbeliefs.</p>","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":" ","pages":"286-305"},"PeriodicalIF":1.5,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142886241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cognitive NeuropsychiatryPub Date : 2024-07-01Epub Date: 2024-12-23DOI: 10.1080/13546805.2024.2443057
Max Coltheart, Martin Davies
{"title":"Delusional belief about location (\"reduplicative paramnesia\").","authors":"Max Coltheart, Martin Davies","doi":"10.1080/13546805.2024.2443057","DOIUrl":"10.1080/13546805.2024.2443057","url":null,"abstract":"<p><strong>Introduction: </strong>People admitted to hospital as inpatients following head injury or stroke sometimes form the delusional belief that they are located somewhere else-often, near or in their home. This delusion was first described by Pick, who named it \"reduplicative paramnesia\"; we argue instead for the term \"location delusion\".</p><p><strong>Methods: </strong>We carried out a literature search and identified 112 cases of location delusion published since Pick's original 1903 case.</p><p><strong>Results: </strong>We found that, in this cohort of patients, the belief about being located elsewhere than the hospital is elaborated into more specific delusional beliefs about just where the patient is located (e.g., beliefs that involve mislocation of the hospital). We identified eight specific location beliefs and offered a two-factor motivational explanation of these eight forms of location delusion. The patient wishes to be somewhere more congenial, that wish becomes a hypothesis (as occurs in normal belief formation), and then, because these patients have impaired ability to evaluate hypotheses, the hypothesis is accepted and maintained as a (delusional) belief.</p><p><strong>Conclusion: </strong>Our previous papers on the two-factor theory of delusional belief focussed on fully neuropsychological delusions. Here we propose that this theory can also explain delusions generated by motivational influences.</p>","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":" ","pages":"268-285"},"PeriodicalIF":1.5,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Neuroimaging assessment of basal ganglia volumes in Tourette Syndrome: a systematic review and meta-analysis.","authors":"Hanife Ertürk, Emre Ertürk, Evrim Aktepe, Lütfiye Bikem Süzen","doi":"10.1080/13546805.2024.2439800","DOIUrl":"10.1080/13546805.2024.2439800","url":null,"abstract":"<p><strong>Introduction: </strong>An increasing number of studies indicate that anatomical, physiological, and histological differences in the basal ganglia(BG) lie in the etiology of Tourette Syndrome(TS). However, the fact that there are very few studies on the anatomy of the BG in TS, small sample sizes, and unclear information as a consequence of these studies' contradictory findings is a significant gap in the scientific literature. The current systematic review and meta-analysis were performed to examine the differences in BG volumes between TS and controls.</p><p><strong>Method: </strong>The protocol was registered with PROSPERO(CRD42023445845). Pertaining studies were ascertained via a search of the published literature in academic databases. The software Comprehensive Meta-Analysis was utilised for statistical analysis.</p><p><strong>Results: </strong>527 articles were reached, and after the exclusion stages, 8 articles remained for the current systematic review and 7 articles for the quantitative meta-analysis. After evaluating each component of the BG individually, no difference was found between the BG volumes of controls and TS.</p><p><strong>Conclusion: </strong>The failure to discover the predicted volume difference can be explained by either the severity of the tic or the exclusion of comorbidity. The difference in BG volume is likely related to TS cases with more severe tics and severe comorbidities.</p>","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":" ","pages":"256-267"},"PeriodicalIF":1.5,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142820109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cognitive NeuropsychiatryPub Date : 2024-05-01Epub Date: 2024-07-28DOI: 10.1080/13546805.2024.2364960
Ho Tae Jeong, Young Chul Youn, Kwang-Yeol Park, Byung-Sun Choi, Taek-Kyun Nam, Hyun Ho Sung
{"title":"Difference between subjective and objective cognitive decline confirmed by power spectral density.","authors":"Ho Tae Jeong, Young Chul Youn, Kwang-Yeol Park, Byung-Sun Choi, Taek-Kyun Nam, Hyun Ho Sung","doi":"10.1080/13546805.2024.2364960","DOIUrl":"10.1080/13546805.2024.2364960","url":null,"abstract":"<p><strong>Introduction: </strong>The study aims to use power spectrum changes in subjective cognitive decline (SCD) and amnestic mild cognitive impairment (aMCI), preclinical stages of Alzheimer's disease (AD), for future biomarker studies in early AD diagnosis.</p><p><strong>Methods: </strong>We recruited 23 SCD and 32 aMCI subjects and conducted comparative analysis using relative power spectral density (PSD). Automated preprocessing and statistical analysis were performed using iSync Brain® (iMediSync Inc., Republic of Korea) (https://isyncbrain.com/).</p><p><strong>Results: </strong>Theta band power in the temporal region was 14.826 ± 7.2394 for the SCD group and 20.003 ± 10.1768 for the aMCI group. In the parietal region, theta band power was 13.614 ± 7.5689 for SCD and 19.894 ± 11.1387 for aMCI. Beta1 band power in the frontal region was 6.639 ± 2.2904 for SCD and 5.465 ± 1.8907 for aMCI, and in the temporal region it was 7.359 ± 2.5619 for SCD and 5.921 ± 2.1605 for aMCI.</p><p><strong>Conclusion: </strong>PSD analysis of resting-state EEG predicted SCD, a preclinical stage of AD. This cross-sectional study observed electrical-physiological characteristics of preclinical AD; however, follow-up studies are needed to evaluate predictive value for future cognitive decline.</p>","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":" ","pages":"194-207"},"PeriodicalIF":1.5,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141789801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Information gathered through draws-to-decision, social functioning, and personal recovery among patients with schizophrenia in Japan.","authors":"Seiichi Watanabe, Takamichi Taniguchi, Motoko Sugihara","doi":"10.1080/13546805.2024.2367269","DOIUrl":"10.1080/13546805.2024.2367269","url":null,"abstract":"<p><strong>Introduction: </strong>In schizophrenia, social functioning and personal recovery are pivotal outcomes potentially influenced by cognitive biases such as Jumping to Conclusions (JTC). Despite their significance, the relationship between JTC, social functioning, and personal recovery remains unclear. This study aims to investigate this relationship to inform tailored interventions for schizophrenia management.</p><p><strong>Methods: </strong>Data were collected from 94 schizophrenia patients using standardised measures. The Beads Task assessed JTC, whereas the Brief PANSS, TMT-J, SLOF-J, and RAS-J evaluated psychiatric symptoms, neurocognitive functioning, social functioning, and personal recovery, respectively. Statistical analyses included correlation and hierarchical regression.</p><p><strong>Results: </strong>Correlation analyses revealed a significant negative correlation between JTC and personal recovery (<i>r</i> = -0.27, <i>p</i> < 0.05). Hierarchical regression indicated JTC as a significant negative predictor of personal recovery (<i>β</i> = -0.33, <i>p</i> = 0.01). No significant correlation was found between JTC and social functioning.</p><p><strong>Discussion: </strong>Increased JTC was associated with lower levels of personal recovery in schizophrenia patients, independent of demographic and clinical factors. In the case of individuals with schizophrenia who demonstrate JTC, there is a potential to suggest the paradox of insight or apparent personal recovery scores.</p>","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":" ","pages":"208-218"},"PeriodicalIF":1.5,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141494222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cognitive NeuropsychiatryPub Date : 2024-05-01Epub Date: 2024-03-29DOI: 10.1080/13546805.2024.2335103
Wendy A Torrens, Jenna N Pablo, Marian E Berryhill, Sarah M Haigh
{"title":"Pattern glare sensitivity distinguishes subclinical autism and schizotypy.","authors":"Wendy A Torrens, Jenna N Pablo, Marian E Berryhill, Sarah M Haigh","doi":"10.1080/13546805.2024.2335103","DOIUrl":"10.1080/13546805.2024.2335103","url":null,"abstract":"<p><strong>Introduction: </strong>Schizophrenia and autism spectrum disorder are distinct neurodevelopmental disorders sharing clinically relevant behaviours. However, early sensory responses show divergent responses. Individuals with schizophrenia typically exhibit cortical <i>hypo-excitability</i> whereas individuals with autism show cortical <i>hyperexcitability</i>. Identifying reliable neurobiological differences between the disorders can diminish misdiagnosis and optimise treatments.</p><p><strong>Methods: </strong>The pattern glare test (PGT) is a simple measure of behavioural hyperexcitability. It measures the number of illusions seen in a static horizontal grating. We collected PGT data from non-clinical adults varying in traits of autism and schizophrenia (schizotypy). 576 undergraduate students completed an online survey consisting of the Schizotypal Personality Questionnaire - Brief Revised, the Autism Spectrum Quotient, and the PGT.</p><p><strong>Results: </strong>Subclinical autism and schizotypy traits were highly <i>positively</i> correlated. However, only schizotypy scores were significantly predictive of reporting more pattern glare (PG) illusions. When assessing the subcomponents of the schizotypy and autism scores, positive and disorganised schizotypy traits were predictive of reporting more PG illusions. Whereas, subclinical autism factors were not predictive of PG illusions.</p><p><strong>Conclusions: </strong>High schizotypy performed the PGT in a manner consistent with behavioural hyperexcitability. The PGT distinguished subclinical autistic traits from schizotypy, suggesting potential clinical application.</p>","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":" ","pages":"155-172"},"PeriodicalIF":1.5,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11296901/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140319819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}