Cognitive Neuropsychiatry最新文献

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Immediate post performance judgements about cognitive performance in schizophrenia and bipolar disorder: associations with test performance and subjective overall judgments regarding abilities. 精神分裂症和双相情感障碍患者表现后对认知表现的即时判断:与测试表现和对能力的主观总体判断的关联。
IF 1.7 4区 医学
Cognitive Neuropsychiatry Pub Date : 2023-11-01 Epub Date: 2023-11-30 DOI: 10.1080/13546805.2023.2276972
Nina Dalkner, Raeanne C Moore, Colin A Depp, Robert A Ackerman, Amy E Pinkham, Philip D Harvey
{"title":"Immediate post performance judgements about cognitive performance in schizophrenia and bipolar disorder: associations with test performance and subjective overall judgments regarding abilities.","authors":"Nina Dalkner, Raeanne C Moore, Colin A Depp, Robert A Ackerman, Amy E Pinkham, Philip D Harvey","doi":"10.1080/13546805.2023.2276972","DOIUrl":"10.1080/13546805.2023.2276972","url":null,"abstract":"<p><strong>Introduction: </strong>The study explored associations between the accuracy of post assessment judgements of cognitive performance with global self-assessments of psychosocial functioning compared to evaluations generated by observers in schizophrenia and bipolar disorder.</p><p><strong>Methods: </strong>An abbreviated cognitive assessment based on the MATRICS Consensus Cognitive Battery was administered to 122 individuals with schizophrenia and 113 with bipolar disorder. They provided self-estimates of their performance after each subtest. In addition, self-reports on cognition, social cognition, and everyday functioning were collected and compared to observer ratings.</p><p><strong>Results: </strong>Both groups overestimated their cognitive function, but in bipolar disorder, there was 30% shared variance between task performance and self-rated task performance (vs. 5% in schizophrenia). Significant correlations were found between self-reported everyday outcomes and both actual and self-assessed performance. In schizophrenia, immediate judgements were only related to self-rated functioning, not to observer rated functioning. In bipolar disorder, impairments in self-assessment of performance correlated with observer ratings of cognitive ability, which was not observed in schizophrenia.</p><p><strong>Conclusions: </strong>While both groups showed correlations between cognitive performance and introspective accuracy, individuals with bipolar disorder showed higher accuracy in assessing their cognitive performance and other outcomes. Notably, impairments in introspective accuracy were associated with observer-rated functioning exclusively in bipolar disorder.</p>","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":" ","pages":"450-466"},"PeriodicalIF":1.7,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10841634/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71523348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cognitive profile in functional disorders. 功能性障碍的认知特征。
IF 1.7 4区 医学
Cognitive Neuropsychiatry Pub Date : 2023-11-01 Epub Date: 2023-11-30 DOI: 10.1080/13546805.2023.2275336
Eka Roivainen, Maria Peura, Jukka Pätsi
{"title":"Cognitive profile in functional disorders.","authors":"Eka Roivainen, Maria Peura, Jukka Pätsi","doi":"10.1080/13546805.2023.2275336","DOIUrl":"10.1080/13546805.2023.2275336","url":null,"abstract":"<p><strong>Introduction: </strong>Patients with functional disorders (FD) often experience cognitive problems such as forgetfulness and distractibility alongside physical symptoms that cannot be attributed to a known somatic disease.</p><p><strong>Method: </strong>Test scores of cognitive tests and psychiatric rating scales of 100 outpatients diagnosed with a functional disorder were compared to a control group (n = 300) of patients with other diagnoses and to test norms for the general population.</p><p><strong>Results: </strong>Out of the 100 patients with functional disorders, 59 reported significant subjective cognitive symptoms. A moderate difference (d = 0.5-0.7) was found between the FD group mean and the population mean in processing speed tests, as well as in four psychiatric rating scales (depression, anxiety, phobias, somatisation) but there were no statistically significant differences in verbal and nonverbal reasoning or in logical memory. Somatisation and logical verbal memory scores were higher in the FD group compared to the control group.</p><p><strong>Conclusion: </strong>The findings of the study suggest that a decline in processing speed is a central feature in the cognitive profile of patients with functional disorders.</p>","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":" ","pages":"424-436"},"PeriodicalIF":1.7,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54232077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The association between visual hallucinations and secondary psychosis: a systematic review and meta-analysis. 视觉幻觉与继发性精神病的关系:一项系统综述和荟萃分析。
IF 1.7 4区 医学
Cognitive Neuropsychiatry Pub Date : 2023-11-01 Epub Date: 2023-11-30 DOI: 10.1080/13546805.2023.2266872
Graham Blackman, Amber Kaur Dadwal, Maria Teixeira-Dias, Dominic Ffytche
{"title":"The association between visual hallucinations and secondary psychosis: a systematic review and meta-analysis.","authors":"Graham Blackman, Amber Kaur Dadwal, Maria Teixeira-Dias, Dominic Ffytche","doi":"10.1080/13546805.2023.2266872","DOIUrl":"10.1080/13546805.2023.2266872","url":null,"abstract":"<p><strong>Introduction: </strong>Visual hallucinations are often considered to be suggestive of a secondary cause of psychosis, however, this association has never been assessed meta-analytically. We aimed to compare the presence of visual hallucinations in patients with psychosis due to a primary or secondary cause.</p><p><strong>Method: </strong>We conducted a meta-analysis of case-control studies directly comparing primary and secondary psychosis. A random-effects model, following the DerSimonian and Laird method, was used to pool studies and generate overall odds ratios (OR), 95% confidence intervals (CI) and prediction intervals (PI).</p><p><strong>Results: </strong>Fourteen studies (904 primary and 804 secondary psychosis patients) were included. Visual hallucinations were significantly associated with secondary psychosis (OR = 3.0, 95% CI = 1.7-5.1, <i>p </i>< 0.001) with moderate between-study heterogeneity (I<sup>2 </sup>= 70%). Subgroup analysis by type of secondary psychosis (organic, drug-induced, mixed) was non-significant. Analysis of the content of visual hallucinations (51 primary and 142 secondary psychosis patients) found hallucinations of inanimate objects were significantly more likely to be associated with secondary psychosis (OR = 0.1, 95% CI = 0.01-0.8, <i>p </i>= 0.03).</p><p><strong>Conclusions: </strong>Visual hallucinations were strongly associated with a secondary cause of psychosis. The presence of visual hallucinations in a patient presenting with psychosis may serve as a potential \"red flag\" for a secondary cause and warrant further investigation.</p>","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":" ","pages":"391-405"},"PeriodicalIF":1.7,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71434893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Associations between intraindividual reaction time variability and prospective memory performance in patients with schizophrenia and healthy controls. 精神分裂症患者和健康对照者的个体反应时间变异性与前瞻记忆表现之间的关系
IF 1.7 4区 医学
Cognitive Neuropsychiatry Pub Date : 2023-09-01 Epub Date: 2023-09-04 DOI: 10.1080/13546805.2023.2255344
Jia-Li Liu, Tao Chen, Ji-Fang Cui, Hai-Song Shi, Ming-Yuan Gan, Ya Wang
{"title":"Associations between intraindividual reaction time variability and prospective memory performance in patients with schizophrenia and healthy controls.","authors":"Jia-Li Liu, Tao Chen, Ji-Fang Cui, Hai-Song Shi, Ming-Yuan Gan, Ya Wang","doi":"10.1080/13546805.2023.2255344","DOIUrl":"10.1080/13546805.2023.2255344","url":null,"abstract":"<p><p><i>Introduction:</i> Patients with schizophrenia exhibit prospective memory (PM) impairment. Intraindividual reaction time variability (IIRTV) is an index of attentional control that is required for PM. This study examined the differences in IIRTV between patients with schizophrenia and healthy controls and the relationship between IIRTV and PM performance.<i>Method:</i> Thirty-nine patients with schizophrenia and forty-two healthy controls were recruited to complete a PM task and the Sustained Attention to Response Task. IIRTV was calculated as the coefficient of variation (mean/SD) of reaction time over correctly responded trials in these tasks.<i>Results:</i> Patients with schizophrenia showed lower PM accuracy and increased IIRTV, while the associations between PM accuracy and IIRTV were significant in healthy controls but not in patients with schizophrenia.<i>Conclusion:</i> These findings suggest impaired PM and relationship between PM and attentional control in patients with schizophrenia.</p>","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":" ","pages":"333-341"},"PeriodicalIF":1.7,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10519943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reversal learning in those with early psychosis features contingency-dependent changes in loss response and learning. 早期精神病患者的反向学习表现为损失反应和学习的偶然性依赖性变化。
IF 1.7 4区 医学
Cognitive Neuropsychiatry Pub Date : 2023-09-01 Epub Date: 2023-11-05 DOI: 10.1080/13546805.2023.2259019
Andrea Baker, Shuichi Suetani, Peter Cosgrove, Dan Siskind, Graham K Murray, James G Scott, James P Kesby
{"title":"Reversal learning in those with early psychosis features contingency-dependent changes in loss response and learning.","authors":"Andrea Baker, Shuichi Suetani, Peter Cosgrove, Dan Siskind, Graham K Murray, James G Scott, James P Kesby","doi":"10.1080/13546805.2023.2259019","DOIUrl":"10.1080/13546805.2023.2259019","url":null,"abstract":"<p><strong>Introduction: </strong>People with psychotic disorders commonly feature broad decision-making impairments that impact their functional outcomes. Specific associative/reinforcement learning problems have been demonstrated in persistent psychosis. But these phenotypes may differ in early psychosis, suggesting that aspects of cognition decline over time.</p><p><strong>Methods: </strong>The present proof-of-concept study examined goal-directed action and reversal learning in controls and those with early psychosis.</p><p><strong>Results: </strong>Equivalent performance was observed between groups during outcome-specific devaluation, and reversal learning at an 80:20 contingency (reward probability for high:low targets). But when the low target reward probability was increased (80:40) those with early psychosis altered their response to loss, whereas controls did not. Computational modelling confirmed that in early psychosis there was a change in punishment learning that increased the chance of staying with the same stimulus after a loss, multiple trials into the future. In early psychosis, the magnitude of this response was greatest in those with higher IQ and lower clinical severity scores.</p><p><strong>Conclusions: </strong>We show preliminary evidence that those with early psychosis present with a phenotype that includes altered responding to loss and hyper-adaptability in response to outcome changes. This may reflect a compensatory response to overcome the milieu of corticostriatal changes associated with psychotic disorders.</p>","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":" ","pages":"342-360"},"PeriodicalIF":1.7,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41173435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unique contributions of specific neuropsychiatric symptoms to caregiver burden in informal caregivers family members of patients with dementia. 特定神经精神症状对痴呆症患者非正式照顾者家庭成员照顾者负担的独特贡献。
IF 1.7 4区 医学
Cognitive Neuropsychiatry Pub Date : 2023-09-01 Epub Date: 2023-09-05 DOI: 10.1080/13546805.2023.2255338
Miroslav Hanzevacki, Jelena Lucijanic, Dina Librenjak, Marko Lucijanic, Vesna Juresa
{"title":"Unique contributions of specific neuropsychiatric symptoms to caregiver burden in informal caregivers family members of patients with dementia.","authors":"Miroslav Hanzevacki, Jelena Lucijanic, Dina Librenjak, Marko Lucijanic, Vesna Juresa","doi":"10.1080/13546805.2023.2255338","DOIUrl":"10.1080/13546805.2023.2255338","url":null,"abstract":"<p><strong>Introduction: </strong>We aimed to evaluate how the presence of individual neuropsychiatric symptoms in non-institutionalised patients with dementia is associated with caregiver burden of their informal caregivers, family members.</p><p><strong>Methods: </strong>We performed a cross-sectional study on a total of 131 pairs of one informal caregiver family member and non-institutionalised patient with dementia in a family medicine practices in a city of Zagreb, Croatia. Caregiver measures included Zarit Burden Interview (ZBI) whereas patient measures included Mini mental state examination (MMSE), Barthel index and Neuropsychiatric Inventory Questionnaire (NPI-Q).</p><p><strong>Results: </strong>Total NPI-Q score explained 21% of overall burden. In order of strength of the association, after adjustments for age, sex, MMSE and Barthel index, overall burden was significantly associated with higher NPI-Q scores for agitation/aggression, apathy/indifference, irritability/lability, disinhibition, motor disturbance, appetite/eating, depression/dysphoria, anxiety, elation/euphoria and nighttime behaviours. When evaluating mutually independent contribution of unique NPI-Q symptoms to caregiver burden, agitation/aggression and apathy/indifference remained only two mutually independently associated symptoms, each explaining 5% of overall burden in this context.</p><p><strong>Conclusions: </strong>Informal caregivers who provide for family members with dementia suffering from agitation/aggression or apathy/indifference should be recognised as under special risk for the development of caregiver burden and considered as candidates for early targeted interventions.</p>","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":" ","pages":"327-332"},"PeriodicalIF":1.7,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10155339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Early-onset schizophrenia: studying the links between cognitive and clinical dimensions. 早发性精神分裂症:研究认知和临床维度之间的联系。
IF 1.7 4区 医学
Cognitive Neuropsychiatry Pub Date : 2023-09-01 Epub Date: 2023-11-05 DOI: 10.1080/13546805.2023.2266871
Emmanuelle Dor-Nedonsel, Arnaud Fernandez, Marie-Line Menard, Valeria Manera, Gaëlle Laure, Susanne Thümmler, Florence Askenazy
{"title":"Early-onset schizophrenia: studying the links between cognitive and clinical dimensions.","authors":"Emmanuelle Dor-Nedonsel, Arnaud Fernandez, Marie-Line Menard, Valeria Manera, Gaëlle Laure, Susanne Thümmler, Florence Askenazy","doi":"10.1080/13546805.2023.2266871","DOIUrl":"10.1080/13546805.2023.2266871","url":null,"abstract":"<p><strong>Background: </strong>Early-onset schizophrenia (EOS), a rare and severe chronic psychiatric condition, is defined by an onset of schizophrenia symptoms before the age of 18. Core symptoms also include cognitive impairments. However, little is known about links between psychiatric symptoms of EOS and cognitive abilities.</p><p><strong>Objective: </strong>To explore the clinical and neurocognitive profiles of EOS patients and their links.</p><p><strong>Method: </strong>EOS patients have been phenotyped using standardised psychiatric assessments for DSM-5 diagnoses (K-SADS-PL) and for symptoms (PANSS and SANS), together with neurocognitive evaluations.</p><p><strong>Results: </strong>The EOS sample (<i>n</i> = 27, 12.4 +/-3.2 years) presented hallucinations (83%), negative symptoms (70%) and delusion (59%). 81% of patients presented comorbidities such as anxiety disorders (33%), autism spectrum disorder (26%) and attention-deficit hyperactivity disorder (26%). Patients presented borderline intellectual deficiency (total IQ = 72.5 +/-4.7), with low performances in working memory subtest. We highlight a positive correlation between the IQ and intensity of positive symptoms (PANSS) and between the IQ and a first treatment being administered at an older age. We also highlight a negative correlation between the IQ and attention items of SANS.</p><p><strong>Conclusion: </strong>Cognitive skills are correlated with symptom intensity in EOS patients. An older age of onset seems to be a protective factor for cognitive development.</p>","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":" ","pages":"377-390"},"PeriodicalIF":1.7,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41219708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Contrasting social knowledge and theory of mind patterns in adults with personality disorders, schizophrenia spectrum disorders, and healthy controls. 对患有人格障碍、精神分裂症谱系障碍和健康对照的成年人的社会知识和心理模式理论进行对比。
IF 1.7 4区 医学
Cognitive Neuropsychiatry Pub Date : 2023-09-01 Epub Date: 2023-11-05 DOI: 10.1080/13546805.2023.2259021
Mireille Lampron, Claudia Savard, Allyson Bernier, Maude Payant, Stéphane Sabourin, Amélie M Achim
{"title":"Contrasting social knowledge and theory of mind patterns in adults with personality disorders, schizophrenia spectrum disorders, and healthy controls.","authors":"Mireille Lampron, Claudia Savard, Allyson Bernier, Maude Payant, Stéphane Sabourin, Amélie M Achim","doi":"10.1080/13546805.2023.2259021","DOIUrl":"10.1080/13546805.2023.2259021","url":null,"abstract":"<p><strong>Introduction: </strong>Personality disorders (PD) and schizophrenia spectrum disorders (SSD) are distinct conditions displaying common symptoms, like impairments in social cognition, that make them hard to distinguish, especially in severe cases. To date, few studies have compared theory of mind skills in these two disorders, and none have compared social knowledge skills. This study aims to compare the social cognitive abilities of patients with these conditions.</p><p><strong>Method: </strong>Non-parametric analyses of covariance were used to compare severe PD patients (<i>n</i> = 37), SSD patients (<i>n</i> = 44), and healthy controls (HC; <i>n</i> = 49) on the Social Knowledge Test and two measures of theory of mind: the Reading the Mind in the Eyes Test and the Combined Stories Test, which incorporates items from various widely used tests.</p><p><strong>Results: </strong>While no significant group differences were found on the Social Knowledge Test, SSD patients performed lower than the HC group on both theory of mind tests. PD patients only had lower performance than the HC group on specific items from the Combined Stories Test.</p><p><strong>Conclusions: </strong>PD and SSD patients demonstrated distinctive patterns of social cognitive impairments, with items of greater complexity or with an affective orientation being the most discriminant for PD.</p>","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":" ","pages":"361-376"},"PeriodicalIF":1.7,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41163348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neuropsychiatric features of Parkinson's disease in the era prior to the use of dopaminergic therapies. 使用多巴胺能疗法之前帕金森病的神经精神特征。
IF 1.7 4区 医学
Cognitive Neuropsychiatry Pub Date : 2023-07-01 Epub Date: 2023-05-12 DOI: 10.1080/13546805.2023.2212151
Chengyu Zhang, Suzanne Reeves, Anthony S David, Harry Costello, Jonathan Rogers
{"title":"Neuropsychiatric features of Parkinson's disease in the era prior to the use of dopaminergic therapies.","authors":"Chengyu Zhang,&nbsp;Suzanne Reeves,&nbsp;Anthony S David,&nbsp;Harry Costello,&nbsp;Jonathan Rogers","doi":"10.1080/13546805.2023.2212151","DOIUrl":"10.1080/13546805.2023.2212151","url":null,"abstract":"<p><strong>Background: </strong>Psychosis in Parkinson's disease includes hallucinations and delusions. Other non-psychotic neuropsychiatric features include depression, anxiety and apathy. There is currently controversy over whether psychosis in Parkinson's is an intrinsic part of the disorder or the result of dopaminergic medications. This study aimed to examine a historical cohort of individuals with Parkinson's prior to the use of dopaminergic therapy to assess the prevalence of psychotic and other neuropsychiatric features.</p><p><strong>Methods: </strong>The case notes of patients with Parkinson's disease admitted to the National Hospital for Neurology and Neurosurgery, London between 1924 and 1946 were examined. Demographic and clinical variables were extracted along with any neuropsychiatric features. Cases meeting criteria for encephalitis lethargica were excluded.</p><p><strong>Results: </strong>115 cases of individuals with Parkinson's disease were identified. 58 (41.7%) were female. Mean age was 54.0 (SD 9.6) years and mean time since Parkinson's diagnosis was 5.3 (SD 5.7) years. No individuals met criteria for encephalitis lethargica. No cases of hallucinations or delusions were reported. There was one case of an illusion in a patient who was using anticholinergic medication. Other neuropsychiatric features reported were sleep disorder (present in 10, 8.7%), depression (8, 7.0%), memory impairment (5, 4.3%), impulsivity (4, 3.5%), bradyphrenia (4, 3.5%), impaired attention (3, 2.6%), anxiety (1, 0.9%), fatigue (1, 0.9%) and apathy (1, 0.9%).</p><p><strong>Conclusions: </strong>Prior to the use of dopaminergic therapies, patients with Parkinson's disease admitted to hospital rarely, if ever, reported psychotic symptoms, although other neuropsychiatric symptoms were more prevalent. The main limitation is that a lack of systematic enquiry about psychotic symptoms may have resulted in underreporting.</p>","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":" ","pages":"243-252"},"PeriodicalIF":1.7,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9439921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Dysregulation of the autonomic nervous system in adult attention deficit hyperactivity disorder. A systematic review. 成人注意力缺陷多动障碍的自主神经系统失调。系统的回顾。
IF 1.7 4区 医学
Cognitive Neuropsychiatry Pub Date : 2023-07-01 Epub Date: 2023-09-13 DOI: 10.1080/13546805.2023.2255336
Lennard Geiss, Mark Stemmler, Beate Beck, Thomas Hillemacher, Michael Widder, Katharina M Hösl
{"title":"Dysregulation of the autonomic nervous system in adult attention deficit hyperactivity disorder. A systematic review.","authors":"Lennard Geiss,&nbsp;Mark Stemmler,&nbsp;Beate Beck,&nbsp;Thomas Hillemacher,&nbsp;Michael Widder,&nbsp;Katharina M Hösl","doi":"10.1080/13546805.2023.2255336","DOIUrl":"10.1080/13546805.2023.2255336","url":null,"abstract":"<p><p><b>Background:</b> Adult Attention Deficit Hyperactivity Disorder (aADHD) is characterised by inattention, hyperactivity, impulsivity, and emotional instability, all of which were linked to altered modulation of the autonomic nervous system. This and the clinical effectiveness of sympathomimetic medication raised the question if autonomic modulation is altered in aADHD patients.<b>Methods:</b> We systematically searched PubMed, Cochrane Library, and Web Of Science for publications investigating autonomic modulation in aADHD and controls during resting-state and/or under task conditions.<b>Results:</b> We reviewed 15 studies involving 846 participants (424 aADHD and 422 controls), including 4 studies on sympathetic tone at rest, 13 studies on sympathetic modulation during tasks, 3 studies on resting state parasympathetic modulation and 3 papers on task-related parasympathetic modulation. Studies comprised measurements of electrodermal activity, heart rate variability, blood pressure variability, blood volume pulse, pre-ejection period, and baroreflex sensitivity. 2 studies reported reduced sympathetic tone in aADHD; 7 papers described lower sympathetic reactivity to task demands in this cohort. One study linked aADHD to impaired vagal tone, while no indications of altered tasks-related parasympathetic reactivity in aADHD patients were reported.<b>Conclusion:</b> The reviewed data revealed impaired cardiovascular autonomic modulation in aADHD patients, predominantly in sympathetic modulation and during stress exposure.</p>","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":" ","pages":"285-306"},"PeriodicalIF":1.7,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10590743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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