Cognitive Neuropsychiatry最新文献_第4页

The presence and severity of neuropsychiatric symptoms and their association with quality of life among patients with dementia. 痴呆症患者神经精神症状的存在和严重程度及其与生活质量的关系。

IF 1.7 4区医学

Cognitive Neuropsychiatry Pub Date : 2023-07-01 Epub Date: 2023-09-04 DOI: 10.1080/13546805.2023.2255342

Banan Alb'ool, Abdallah Abu Khait

{"title":"The presence and severity of neuropsychiatric symptoms and their association with quality of life among patients with dementia.","authors":"Banan Alb'ool, Abdallah Abu Khait","doi":"10.1080/13546805.2023.2255342","DOIUrl":"10.1080/13546805.2023.2255342","url":null,"abstract":"Background: Neuropsychiatric symptoms are common manifestations of dementia. The presence and severity of these symptoms differ depending on different personal and contextual factors.Purpose: This study aimed to investigate the presence and predictors of neuropsychiatric symptoms and the association between the severity of these symptoms and the quality of life in a sample of patients with dementia in Jordan.Methods: In this cross-sectional study, 112 patients with dementia residing in Jordanian nursing homes were recruited using the consecutive sampling method.Results: The mean severity of neuropsychiatric symptoms was 9.58. The most prevalent neuropsychiatric symptoms among patients were depression (61.6%), followed by irritability (55.4%), and a feeling of euphoria (54.5%). The regression analysis results indicated that gender, marital status, and dementia severity significantly predicted the neuropsychiatric symptoms severity score and explained 17.70% of the variance. A significant negative correlation between the severity of neuropsychiatric symptoms and quality of life was found.Conclusion: The study's results indicate that our sample reported mild neuropsychiatric symptoms. These symptoms' high prevalence and persistence negatively impact patients' quality of life. The study's results can help mental health nurses determine the factors impacting effective treatment strategies to combat these symptoms. Future longitudinal studies are warranted to help explain the importance of early diagnosis and management of these symptoms in preventing dementia progression.","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":" ","pages":"307-325"},"PeriodicalIF":1.7,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10203195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Schizophrenia patients perform as well as healthy controls on creative problem solving when fluid intelligence is accounted for. 当考虑到流体智力时，精神分裂症患者在创造性解决问题方面的表现与健康对照组一样好。

IF 1.7 4区医学

Cognitive Neuropsychiatry Pub Date : 2023-07-01 Epub Date: 2023-05-22 DOI: 10.1080/13546805.2023.2215921

Hanna Kucwaj, Zdzisław Gajewski, Adam Chuderski

{"title":"Schizophrenia patients perform as well as healthy controls on creative problem solving when fluid intelligence is accounted for.","authors":"Hanna Kucwaj, Zdzisław Gajewski, Adam Chuderski","doi":"10.1080/13546805.2023.2215921","DOIUrl":"10.1080/13546805.2023.2215921","url":null,"abstract":"Introduction: This study examined creative problem solving in schizophrenia. We aimed to verify three hypotheses: (H1) schizophrenia patients differ from healthy controls in the accuracy of creative problem solving; (H2) schizophrenia patients are less effective at evaluating and rejecting incorrect associations and (H3) have a more idiosyncratic way of searching for semantic associations compared to controls.Methods: Six Remote Associates Test (RAT) items and three insight problems were applied to schizophrenia patients and healthy controls. We compared groups on the overall accuracy in the tasks to verify H1 and developed a novel method of comparing the patterns of errors in the RAT to verify H2 and H3. We controlled for fluid intelligence to eliminate this significant source of variation, as typically creativity and intelligence are significantly related.Results: Bayesian factor analysis did not support the group differences in either insight problems and RAT accuracy or the patterns of RAT errors.Conclusions: The patients performed as well as the controls on both tasks. Analysis of RAT errors suggested that the process of searching for remote associations is comparable in both groups. It is highly improbable that individuals with schizophrenia benefit from their diagnosis during creative problem solving.","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":" ","pages":"253-268"},"PeriodicalIF":1.7,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9499025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Bayesian predictive processing account of Othello syndrome in Parkinson's disease. 帕金森病中奥赛罗综合征的贝叶斯预测处理。

IF 1.7 4区医学

Cognitive Neuropsychiatry Pub Date : 2023-07-01 Epub Date: 2023-06-27 DOI: 10.1080/13546805.2023.2229080

Jennifer A Foley, Cliff Chen, Andrew Paget, Lisa Cipolotti

{"title":"A Bayesian predictive processing account of Othello syndrome in Parkinson's disease.","authors":"Jennifer A Foley, Cliff Chen, Andrew Paget, Lisa Cipolotti","doi":"10.1080/13546805.2023.2229080","DOIUrl":"10.1080/13546805.2023.2229080","url":null,"abstract":"Introduction: Although delusions in Parkinson's disease (PD) are rare, when they occur they frequently take the form of \"Othello syndrome\": the irrational belief that a spouse or partner is being unfaithful. Hitherto dismissed as either a by-product of dopamine therapy or cognitive impairment, there are still no convincing theoretical accounts to explain why only some patients fall prey to this delusion, or why it persists despite clear disconfirmatory evidence.Methods: We discuss the limitations of existing explanations of this delusion, namely hyperdopaminergia-induced anomalous perceptual experiences and cognitive impairment, before describing how Bayesian predictive processing accounts can provide a more comprehensive explanation by foregrounding the importance of prior experience and its impact upon computation of probability. We illustrate this new conceptualisation with three case vignettes.Results: We suggest that in those with prior experience of romantic betrayal, hyperdominergic-induced aberrant prediction errors enable anomalous perceptual experiences to accrue greater prominence, which is then maintained through Bayes-optimal inferencing to confirm cognitive distortions, eliciting and shaping this dangerous delusion.Conclusions: We propose the first comprehensive mechanistic account of Othello syndrome in PD and discuss implications for clinical interventions.","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":" ","pages":"269-284"},"PeriodicalIF":1.7,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9689095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spontaneous perspective-taking and its relation to schizotypy. 自发换位思考及其与精神分裂的关系。

IF 1.7 4区医学

Cognitive Neuropsychiatry Pub Date : 2023-05-01 DOI: 10.1080/13546805.2023.2189575

Mark R Gardner, Tom Buchanan

{"title":"Spontaneous perspective-taking and its relation to schizotypy.","authors":"Mark R Gardner, Tom Buchanan","doi":"10.1080/13546805.2023.2189575","DOIUrl":"https://doi.org/10.1080/13546805.2023.2189575","url":null,"abstract":"ABSTRACT Introduction Patients with schizophrenia differ from healthy controls in the extent that they spontaneously take another’s perspective. For such effects, it is difficult to separate the influence of schizophrenia from multiple potential confounders. Here, for the first time, associations between spontaneous perspective-taking and schizotypy were investigated in a nonclinical population. Methods Adult participants completed both a Schizotypal Personality Questionnaire (SPQ-BRU) and a novel online adaptation of a visual perspective-taking task that required participants to make judgements both from their own perspective and that of a human avatar. Results Response times were elevated when the avatar’s perspective was inconsistent with that of the participant, providing evidence of spontaneous perspective-taking. This demonstrates that the visual perspective-taking task can be successfully implemented in an online format. However, schizotypy did not predict these spontaneous perspective-taking effects. Conclusions Unlike explicit mentalising, this form of implicit mentalising is not affected by nonclinical manifestations of schizotypy traits. This implies that impairment of general neurocognitive function contributes to altered spontaneous perspective-taking in schizophrenia. A novel account based on the cognitive control processes involved in perspective selection and the role of attention in perspective calculation reconciles apparently contradictory findings of earlier studies comparing patients with schizophrenia and healthy controls.","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":"28 3","pages":"181-195"},"PeriodicalIF":1.7,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9562420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cognitive profile in adult women with turner syndrome: IQ split and associations with ADHD and ASD. 特纳综合征成年女性的认知特征:智商分裂及其与ADHD和ASD的关系。

IF 1.7 4区医学

Cognitive Neuropsychiatry Pub Date : 2023-05-01 DOI: 10.1080/13546805.2023.2209312

Hanna Björlin Avdic, Johan Lundin Kleberg, Marcus van der Poll, Louise Frisén, Matilda Hutley, Mandi Sarjanen, Ida Nordgren, Katja Ekholm, Angelica Lindén Hirschberg, Ann Nordgren, Charlotte Willfors

{"title":"Cognitive profile in adult women with turner syndrome: IQ split and associations with ADHD and ASD.","authors":"Hanna Björlin Avdic, Johan Lundin Kleberg, Marcus van der Poll, Louise Frisén, Matilda Hutley, Mandi Sarjanen, Ida Nordgren, Katja Ekholm, Angelica Lindén Hirschberg, Ann Nordgren, Charlotte Willfors","doi":"10.1080/13546805.2023.2209312","DOIUrl":"https://doi.org/10.1080/13546805.2023.2209312","url":null,"abstract":"Introduction: The behavioural phenotype in Turner syndrome (TS) is associated with an uneven cognitive profile and social and executive difficulties. Still, studies in adult populations of TS are scarce, and the interactions between different behavioural domains are unclear. The aim of this study was to examine the cognitive profile in relation to measures of ADHD and ASD in a Swedish sample of 30 adult women with TS.Methods: Standardized psychological tests and questionnaires were used for behavioural assessments in a sample of adult women with a diagnosis of TS (n = 30). Both frequentist and Bayesian statistics were applied.Results: The cognitive profile was characterized by a verbal > non-verbal intelligence quotient (IQ) split, and 77% of the sample displayed a split exceeding cut-off for clinical significance. Symptoms on screening measures reaching thresholds for ADHD were reported in two of the 30 participants (7%) and thresholds for autism spectrum disorders (ASD) in one participant (3%). Bayesian statistics gave substantial evidence for no association between the IQ split and symptoms of ADHD/ASD.Conclusions: These results show that the TS phenotype in adulthood is associated with a clinically significant uneven cognitive profile, and particular impairments in integrative executive functions.","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":"28 3","pages":"207-225"},"PeriodicalIF":1.7,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9560404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Linguistic anomalies observed in the Sentence Completion Test in patients with schizophrenia. 精神分裂症患者句子完成测试中语言异常的观察。

IF 1.7 4区医学

Cognitive Neuropsychiatry Pub Date : 2023-05-01 DOI: 10.1080/13546805.2023.2209313

Young Tak Jo, Ji Soo Lee, Jaiyoung Park, Jungsun Lee, Yeon Ho Joo

{"title":"Linguistic anomalies observed in the Sentence Completion Test in patients with schizophrenia.","authors":"Young Tak Jo, Ji Soo Lee, Jaiyoung Park, Jungsun Lee, Yeon Ho Joo","doi":"10.1080/13546805.2023.2209313","DOIUrl":"https://doi.org/10.1080/13546805.2023.2209313","url":null,"abstract":"Background: Schizophrenia is a chronic, debilitating disorder characterised by distorted thinking, perceptions, behaviours, and even language impairments. We investigated the linguistic anomalies in Korean schizophrenia patients compared to non-psychotic psychiatric controls to determine whether the linguistic anomalies in English speakers with schizophrenia were replicated in Korean speakers.Methods: Thirty-four schizophrenia patients and 70 non-psychotic psychiatric controls were included in this study. The SCT was utilised as the text data for analysis. For linguistic analysis, we evaluated texts regarding semantics and syntax. We separately counted the number of semantic or syntactic errors in the written texts of study participants and compared them between patients and controls.Results: Schizophrenia patients showed significantly more semantic errors (p < .001) and syntactic errors (p < .001) per 1,000 characters than non-psychotic psychiatric controls. Specifically, inappropriate word or syntactic component selection is noticeable in schizophrenia patients. These differences were still significant after adjusting for general intelligence measured by the K-WAIS-IV.Conclusion: Schizophrenia patients showed both semantic and syntactic errors in written language. Moreover, these errors seemed to be partly independent of general intelligence. Notably, patients showed a noticeable number of syntactic errors. Further investigation into the language of patients with schizophrenia and schizophrenia-spectrum disorders is required.","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":"28 3","pages":"226-236"},"PeriodicalIF":1.7,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9558144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

"My mind goes dead … I cannot speak": an expression of DPD. “我的脑子死气沉沉的……我说不出话来”:DPD的一种表达。

IF 1.7 4区医学

Cognitive Neuropsychiatry Pub Date : 2023-05-01 DOI: 10.1080/13546805.2023.2197201

D Goeta, M Mula, M Mayhew, N A Poole

{"title":"\"My mind goes dead … I cannot speak\": an expression of DPD.","authors":"D Goeta, M Mula, M Mayhew, N A Poole","doi":"10.1080/13546805.2023.2197201","DOIUrl":"https://doi.org/10.1080/13546805.2023.2197201","url":null,"abstract":"Introduction: Here we present a case of Depersonalisation-Derealisation Disorder which involves an unusual environmental trigger and profile of symptoms in a patient with an underlying left frontal encephalomalacia.Methods: The clinical information has been collected from multiple neurological, psychiatric, neuropsychological examinations and from the patient's medical records.Results: The neuropsychiatric assessment showed depersonalisation, derealisation, de-somatisation and de-affectualisation, along with a good response to SSRI + Lamotrigine; all typical features of DPD. The neuropsychological assessment showed language problems, and other mild cognitive difficulties that may provide a neuropsychological foundation contributing to the DPD episodes.Discussion and conclusion: Given Mr R's underlying neuropsychological deficit, hearing voices without speech-associated gestures might place excessive demands on his ability to process the information, exacerbating his feelings of threat. This sets up the pattern of suppressed insula activation, and possibly the suppression of the auditory cortex leading to the presented unusual DPD symptoms.","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":"28 3","pages":"196-206"},"PeriodicalIF":1.7,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9558978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fatigue and its relation to general cognition, social cognition and social activity in multiple sclerosis and stroke. 多发性硬化和脑卒中患者疲劳及其与一般认知、社会认知和社会活动的关系。

IF 1.7 4区医学

Cognitive Neuropsychiatry Pub Date : 2023-05-01 DOI: 10.1080/13546805.2023.2178399

Tobias Lohaus, Judith Witt, Anne Schürmeyer, Oliver T Wolf, Patrizia Thoma

{"title":"Fatigue and its relation to general cognition, social cognition and social activity in multiple sclerosis and stroke.","authors":"Tobias Lohaus, Judith Witt, Anne Schürmeyer, Oliver T Wolf, Patrizia Thoma","doi":"10.1080/13546805.2023.2178399","DOIUrl":"https://doi.org/10.1080/13546805.2023.2178399","url":null,"abstract":"Introduction: The relationship between fatigue and (socio-)cognitive deficits in neurological diseases has sparked increasing research interest in the past years. So far, findings are inconsistent. Most studies focused on general cognitive functioning in specific disorders, particularly cancer or multiple sclerosis (MS).Methods: This study aims to examine the relationship between fatigue, social cognition and social activity, also taking into account general cognition, more closely, including a stroke patient group (n = 57), a MS patient group (n = 31) and a healthy control group (n = 20). The participants underwent a comprehensive (socio-)cognitive test battery and completed questionnaires on fatigue and psychopathology which, in addition to fatigue, can also affect (socio-)cognitive performance.Results: In both MS and stroke patients high fatigue scores were observed. Irrespective of aetiology, patients with high and low fatigue did not differ with regard to general cognition and social cognition. However, high fatigue scores were associated with a reduction of social activities in both patient groups. No other significant relationships were observed between fatigue and (socio-)cognitive measures.Conclusions: Future studies ought to further explore the potentially complex nature of fatigue symptoms and their relationship with (socio-)cognitive performance and social activity in neurological populations.","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":"28 3","pages":"165-180"},"PeriodicalIF":1.7,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9558074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The entangled nature of the brain 大脑的纠缠性

IF 1.7 4区医学

Cognitive Neuropsychiatry Pub Date : 2023-04-05 DOI: 10.1080/13546805.2023.2197202

A. Cavanna, G. Purpura, A. Riva, R. Nacinovich

引用次数: 0

Swiss CAT+, a Data-driven Infrastructure for Accelerated Catalysts Discovery and Optimization. 瑞士CAT+，加速催化剂发现和优化的数据驱动基础设施。

IF 1.2 4区医学

Cognitive Neuropsychiatry Pub Date : 2023-03-29 DOI: 10.2533/chimia.2023.154

Paco Laveille, Pascal Miéville, Sourav Chatterjee, Elisa Clerc, Jean-Charles Cousty, Florian De Nanteuil, Erwin Lam, Edy Mariano, Adrian Ramirez, Urielle Randrianarisoa, Keyan Villat, Christophe Copéret, Nicolai Cramer

引用次数: 0