Medicinski Glasnik最新文献_第3页

The correlation between interleukin-6 levels and quality of life in late-stage breast cancer patients with anxiety syndrome at Haji Adam Malik General Hospital Medan. 棉兰哈吉·亚当·马利克综合医院伴焦虑综合征的晚期乳腺癌患者白细胞介素-6水平与生活质量的关系

Medicinski Glasnik Pub Date : 2026-02-27 DOI: 10.17392/2017-23-01

Ella Yunita Daulay, Mustafa Mahmud Amin, Elmeida Effendy, Vita Camellia, Kamal Basri Siregar

{"title":"The correlation between interleukin-6 levels and quality of life in late-stage breast cancer patients with anxiety syndrome at Haji Adam Malik General Hospital Medan.","authors":"Ella Yunita Daulay, Mustafa Mahmud Amin, Elmeida Effendy, Vita Camellia, Kamal Basri Siregar","doi":"10.17392/2017-23-01","DOIUrl":"https://doi.org/10.17392/2017-23-01","url":null,"abstract":"Aim: Breast cancer is the most common cancer found in women including in Indonesia. Breast cancer patients are prone to have anxiety and it affects their quality of life. Interleukin-6 (IL-6) is one of the pro-tumorigenic cytokines that increases in breast cancer and is associated with worse prognosis and cancer metastasis. Several studies demonstrated the correlation between inflammatory cytokines and anxiety disorders. Therefore, this study aimed to determine the correlation between IL-6 and quality of life with anxiety syndrome in patients with late-stage breast cancer.Method: This cross-sectional study involved women with late-stage breast cancer (Stage III and IV) in Haji Adam Malik General Hospital. IL-6 levels were assessed using Sandwich enzyme-linked immunosorbent assay (Sandwich-ELISA). The quality of life and anxiety syndromes were assessed using the European Organization for Research and Treatment of Cancer 30-Item Quality of Life Questionnaire (EORTC QLQ-C30) and Hospital Anxiety and Depression Scale (HADS)-A questionnaire, respectively. Kruskal-Wallis test was used to determine the correlation between variables. A p-value < 0.05 was considered statistically significant.Result: Fifty-nine women met the inclusion criteria. The analysis demonstrated that higher IL-6 levels (p < 0.001) and poor QoL (p < 0.001) were related to severe anxiety disorders in late-stage breast cancer patients.Conclusion: IL-6 level and quality of life were potentially used in the risk stratification and early detection of anxiety syndrome in late-stage breast cancer cases.","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"23 1","pages":"91-94"},"PeriodicalIF":0.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147788389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Continuous positive airway pressure failure in the management of neonatal respiratory distress in a resource limited setting: a prospective observational study. 在资源有限的情况下，持续气道正压失败对新生儿呼吸窘迫的管理：一项前瞻性观察研究。

Medicinski Glasnik Pub Date : 2026-02-27 DOI: 10.17392/2048-23-01

Noor Sameer Yahya, Ahmed Khalil Ibrahim, Aws Al-Numan

{"title":"Continuous positive airway pressure failure in the management of neonatal respiratory distress in a resource limited setting: a prospective observational study.","authors":"Noor Sameer Yahya, Ahmed Khalil Ibrahim, Aws Al-Numan","doi":"10.17392/2048-23-01","DOIUrl":"https://doi.org/10.17392/2048-23-01","url":null,"abstract":"Aim: To determine the frequency and identify predictors of Continuous positive airway pressure (CPAP) failure in neonates of varying gestational ages in a resource-limited setting, where CPAP is often used beyond the preterm population.Methods: Prospective observational study of 119 neonates started on CPAP within 24 hours of birth for respiratory distress. We collected Demographic, clinical, and perinatal data. CPAP failure was defined by persistent hypoxia or severe respiratory distress despite maximal settings, necessitating mechanical ventilation. Univariate and multivariable binary logistic regression analyses identify predictors of CPAP failure.   Results: The CPAP failure rate was 33.6%. Univariate analysis identified lower gestational age ( ≤ 30 weeks), lower birth weight (≤1200 g), female sex, vaginal delivery, and a 5-minute Apgar score < 7 as significant predictors. However, in the multivariable model, only a 5-minute Apgar score < 7 remained an independent predictor (Adjusted Odds Ratio AOR 5.315; p=0.006). Antenatal corticosteroid, age at CPAP initiation, and initial Fraction of inspired oxygen (FiO)₂ were not significant. Neonates with birth weight <1200g had shorter duration of successful CPAP use as revealed by Kaplan-Meier survival analysis (p<0.001) Conclusion: This study confirms that CPAP failure is a frequent and serious problem in our resource-limited NICU. A low 5-minute Apgar score is a significant predictor of failure. To save more newborns, we must focus on improving neonatal resuscitation and make clear guidelines for respiratory care in our specific context.","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"23 1","pages":"95-100"},"PeriodicalIF":0.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147788428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Stem cells and secretome in aplastic anaemia: a bibliometric analysis of global research trends (2018 - 2023) and future directions for regenerative therapies. 再生障碍性贫血中的干细胞和分泌组：对全球研究趋势（2018 - 2023）和再生疗法未来方向的文献计量学分析。

Medicinski Glasnik Pub Date : 2026-02-27 DOI: 10.17392/1992-23-01

Citra Primavita Mayangsari, Harsono Salimo, Yulia Lanti Retno Dewi, Agung Putra, Betty Suryawati, Annang Giri Moelyo

{"title":"Stem cells and secretome in aplastic anaemia: a bibliometric analysis of global research trends (2018 - 2023) and future directions for regenerative therapies.","authors":"Citra Primavita Mayangsari, Harsono Salimo, Yulia Lanti Retno Dewi, Agung Putra, Betty Suryawati, Annang Giri Moelyo","doi":"10.17392/1992-23-01","DOIUrl":"https://doi.org/10.17392/1992-23-01","url":null,"abstract":"Aim: This study analyzed the research trends related to stem cells and secretome in aplastic anemia between 2018 and 2023 using a bibliometric approach to understand developments and research distribution in this field.Methods: The Scopus database was used to search for relevant articles on aplastic anemia and its relationship to stem cells or secretome, collecting publication and citation data found in article titles, abstracts, and keywords. VOSviewer and Biblioshiny bibliometric software were used to visualize author, country, journal, and keyword networks. Visualization maps aimed to highlight the emergence of words and phrases in titles and abstracts.Results: Based on information from 1,405 articles identified from 2018 to 2023, publication numbers experienced significant fluctuations. Research showed that publications on aplastic anemia, stem cells, or secretome increased by an average of 2.52% annually over the past five years. The most productive country was China with 321 documents, while the most productive institution was the Chinese Academy of Medical Sciences & Peking Union Medical College with 53 documents. We identified four cluster groups: \"severe aplastic anemia,\" \"allogeneic stem cell transplantation,\" \"bone marrow failure,\" and \"hematopoietic stem cell transplantation.\"Conclusion: This study provides a comprehensive overview of research trends in aplastic anemia related to stem cells and secretome from 2018 to 2023, highlighting steady growth and key contributors like China. Future research will likely focus on secretome applications and international collaborations to advance regenerative therapies for aplastic anemia.","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"23 1","pages":"23-29"},"PeriodicalIF":0.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147788447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A useful surgical landmark for the trapezio-scaphoid joint. 一个有用的手术标志，为梯形舟状关节。

Medicinski Glasnik Pub Date : 2026-02-27 DOI: 10.17392/2025-23-01

Camillo Fulchignoni, Silvia Pietramala, Chiara Muci, Alessandro El Motassime, Andrea Cruciani, Lorenzo Rocchi, Gianfranco Merendi

{"title":"A useful surgical landmark for the trapezio-scaphoid joint.","authors":"Camillo Fulchignoni, Silvia Pietramala, Chiara Muci, Alessandro El Motassime, Andrea Cruciani, Lorenzo Rocchi, Gianfranco Merendi","doi":"10.17392/2025-23-01","DOIUrl":"https://doi.org/10.17392/2025-23-01","url":null,"abstract":"Aim: Unintended scaphoid excision is a rare but serious complication that can occur during surgical procedures involving the trapezium, including but not limited to trapeziectomy. Although prosthetic replacement is increasingly favored in the treatment of rhizarthrosis, trapeziectomy (with or without ligamentoplasty) remains a widely used and effective option. To reduce the risk of inadvertently removing the scaphoid, we rely on the anatomical intersection between the radial artery branch and the first dorsal compartment tendons as a landmark for identifying the scapho-trapezial joint.Methods: In our Institutiton the, Policlinico Universitario A. Gemelli IRCSS, we have been using a simple landmark to identify scapho-trapezial joint to teach residents: during surgery, after isolating the radial artery, a 16G needle is inserted at the intersection of the extensor tendons and the radial artery branch, followed by fluoroscopy to confirm needle placement in the scapho-trapezial joint. Patients were classified according to Eaton-Littler classification and the accuracy of the Landmark was then assessed among groups.Results: So far we used the landmark on 212 patients. The distribution by Eaton-Littler stage was: 11 stage 1, 63 stage 2, 79 stage 3, and 33 stage 4. The reference point was accurate in 178 cases. No significant differences were found by sexgender or between stages 1, 2 and 3. However, accuracy in stage 4 was significantly lower (p<0.00001).Conclusion: Our results confirm the reliability of this reference point, particularly in stages 1–3. While useful in stage 4, additional caution is required due to slightly reduced precision.","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"23 1","pages":"201-205"},"PeriodicalIF":0.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147788356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of brain injury biomarkers in mild traumatic brain injury with and without computed tomography findings. 轻度外伤性脑损伤中脑损伤生物标志物的评估，有无计算机断层扫描结果。

Medicinski Glasnik Pub Date : 2026-02-27 DOI: 10.17392/2045-23-01

Alma Osmić-Husni, Radivoj Jadrić, Svetlana Jović-Lacković, Aida Žabić, Sabina Čamdžić-Smajić

{"title":"Evaluation of brain injury biomarkers in mild traumatic brain injury with and without computed tomography findings.","authors":"Alma Osmić-Husni, Radivoj Jadrić, Svetlana Jović-Lacković, Aida Žabić, Sabina Čamdžić-Smajić","doi":"10.17392/2045-23-01","DOIUrl":"https://doi.org/10.17392/2045-23-01","url":null,"abstract":"Aim: Mild traumatic brain injury (mTBI) presents diagnostic challenges, with head computed tomography (head CT) often overutilized in emergency settings. Blood biomarkers such as glial fibrillary acidic protein (GFAP) and ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) have shown promise in early injury detection. Aim of this study was to evaluate the diagnostic utility of GFAP and UCH-L1 in identifying   intracranial injuries early and potential reduction in unnecessary head CT scans in mTBI patients.Methods: A prospective study was conducted on 102 adult patients with mTBI. Serum levels of GFAP and UCH-L1 were measured within 12 hours post-injury and compared with head CT findings using appropriate statistical analyses.Results: Both biomarkers demonstrated 100% sensitivity and moderate specificity, with high negative predictive value (NPV), supporting their utility in ruling out injuries detectable on CT.Conclusion: GFAP and UCH-L1 are effective early biomarkers for excluding significant intracranial injuries and may help optimize head CT scan utilization in the acute management of mTBI.","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"23 1","pages":"162-166"},"PeriodicalIF":0.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147788368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of immune responses to zirconia, polyether ether ketone (PEEK), and stainless-steel in orthopaedic implants. 骨科植入物中氧化锆、聚醚醚酮（PEEK）和不锈钢的免疫反应比较

Medicinski Glasnik Pub Date : 2026-02-27 DOI: 10.17392/2037-23-01

Agung Riyanto Budi Santoso, Respati Suryanto Dradjat, Edi Mustamsir, Setyawan Purnomo Sakti, Panji Sananta, Hidayat Sujuti, Heri Suroto

{"title":"Comparison of immune responses to zirconia, polyether ether ketone (PEEK), and stainless-steel in orthopaedic implants.","authors":"Agung Riyanto Budi Santoso, Respati Suryanto Dradjat, Edi Mustamsir, Setyawan Purnomo Sakti, Panji Sananta, Hidayat Sujuti, Heri Suroto","doi":"10.17392/2037-23-01","DOIUrl":"https://doi.org/10.17392/2037-23-01","url":null,"abstract":"Aim: Orthopedic implants must meet specific criteria, including mechanical strength, durability, and biocompatibility. This study compares the immune response of zirconia, polyether ether ketone (PEEK), and stainless-steel implants in vivo, focusing on lymphocyte and fibroblast infiltration as indicators of immune activation.Methods: A total of 27 New Zealand white rabbits were used, with nine animals in each group. Implants of zirconia, PEEK, or stainless steel were surgically placed in the thigh and observed for 4 weeks. Histological analysis measured lymphocyte and fibroblast infiltration at the implant site using a microscope at 400x magnification. Statistical analysis included the Kruskal-Wallis test for group comparisons, followed by Mann-Whitney and Bonferroni correction for pairwise comparisons.Results: The Kruskal-Wallis test showed significant differences in lymphocyte (p=0.002) and fibroblast (p=0.003) counts among the groups. Zirconia exhibited significantly lower lymphocyte (median=0.5) and fibroblast (median=1.0) infiltration compared to stainless steel (lymphocytes: median=3.0, fibroblasts: median=2.0), and PEEK (lymphocytes: median=2.0, fibroblasts: median=3.0). Bonferroni correction confirmed zirconia showed the least immune activation (p<0.0167).Conclusion: Zirconia offers superior biocompatibility with minimal immune response, making it an ideal material for orthopedic implants, particularly for patients with metal sensitivities. PEEK showed moderate immune activation but is helpful for non-load-bearing applications. Stainless Steel induced the highest immune response due to the release of metal ions and corrosion. Zirconia is the most biocompatible material tested, making it a promising choice for orthopedic implants.","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"23 1","pages":"216-220"},"PeriodicalIF":0.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147788396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prophylactic use of rectal diclofenac in mitigating post endoscopic retrograde cholangiopancreatography pancreatitis risk and severity: low- vs high-dose efficacy and timing strategies— a meta-analysis. 预防性使用直肠双氯芬酸减轻内镜逆行胰胆管造影术后胰腺炎的风险和严重程度：低剂量与高剂量的疗效和时机策略&一项荟萃分析

Medicinski Glasnik Pub Date : 2026-02-27 DOI: 10.17392/2057-23-01

Maggie Liberty, Taufik Sungkar, Peggy Liberty

{"title":"Prophylactic use of rectal diclofenac in mitigating post endoscopic retrograde cholangiopancreatography pancreatitis risk and severity: low- vs high-dose efficacy and timing strategies— a meta-analysis.","authors":"Maggie Liberty, Taufik Sungkar, Peggy Liberty","doi":"10.17392/2057-23-01","DOIUrl":"https://doi.org/10.17392/2057-23-01","url":null,"abstract":"Aim: Post endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) is the most prevalent adverse event with significant morbidity following ERCP. Several guidelines have suggested the use of rectal diclofenac as a promising option to prevent PEP. Nonetheless, the recommended optimal dose and timing of administration remain unclear. The aim of this study was to evaluate the efficacy of different doses and timing of rectal diclofenac administration in preventing PEP.Methods: Literature search was conducted on 3 databases: PubMed/MEDLINE, Cochrane Library, and ScienceDirect. The included studies were evaluated for the method and reported data quality. Data were summarized and statistical analyses were performed with RevMan 5.4.1 software.Results: Thirteen eligible studies with a total of 8602 patients undergoing ERCP were included in this study. The result showed A significantly lower moderate-severe PEP prevalence in patients treated with rectal diclofenac compared to control (RR 0.67; 95% CI: 0.51-0.89; p=0.006) was found.  High-dose rectal diclofenac significantly reduced the prevalence of moderate to severe PEP (RR 0.63; 95% CI: 0.450.89; p=0.008). Administering rectal diclofenac before procedure significantly lowered the prevalence of moderate to severe PEP (RR 0.66; 95% CI: 0.47-0.92; p=0.01). Adverse events related to ERCP procedure were comparable in both groups. No adverse event related to rectal diclofenac administration was reported across all studies.Conclusion: High-dose rectal diclofenac administered before ERCP procedure is effective in reducing the prevalence and severity of PEP, and is well tolerated with favourable safety profile.","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"23 1","pages":"68-75"},"PeriodicalIF":0.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147788398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pregnancy outcome after in vitro fertilization: a retrospective cohort study. 体外受精后妊娠结局：回顾性队列研究。

Medicinski Glasnik Pub Date : 2026-02-27 DOI: 10.17392/1959-23-01

Gordana Grgić, Anis Cerovac, Azra Hadžimehmedović, Selma Muratović, Asja Terzić, Ermin Čehić

{"title":"Pregnancy outcome after in vitro fertilization: a retrospective cohort study.","authors":"Gordana Grgić, Anis Cerovac, Azra Hadžimehmedović, Selma Muratović, Asja Terzić, Ermin Čehić","doi":"10.17392/1959-23-01","DOIUrl":"https://doi.org/10.17392/1959-23-01","url":null,"abstract":"Aim: To determine the outcome of pregnancies in women whose pregnancies resulted from in vitro fertilisatio  (IVF) procedure.Methods: This a retrospective cohort study was conducted at the Clinic for Gynecology and Obstetrics, University Clinical Center Tuzla, Bosnia and Herzegovina. Data from the delivery protocol were analyzed over a five-year period, from January 1, 2019, to December 31, 2023. A total of 257 deliveries from IVF pregnancies were analyzed, constituting the study group, while the control group consisted of an equal number of women with spontaneously conceived pregnancies. The following data were analyzed: baseline obstetrics  and neonatal characteristics, and presence of complications during pregnancy and delivery.Results: The average age of pregnant women was higher in the study compared to the control group (p=0.001). The average body weight and body length at birth were lower in the study group (p=0.001). The twin pregnancies were more frequent in the study group (p=0.0001). In the study group it was recorded largest number of primiparous women (p=0.0001). It was found higher number of newborns with Apgar scores <7 at the first and fifth minutes in the study group (p=0.0001). There were higher prevalence of preterm births and cesarean section in the study group (p=0.0001). Fetal asphyxia and breech presentation were more prevalent in the study group (p=0.008 and p<0.0001).Consclusion: Pregnancies resulting from IVF were still riskier than those resulting spontaneously.","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"23 1","pages":"150-155"},"PeriodicalIF":0.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147788419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Minimal clinically important difference (MCID)-based analysis of single-versus two-level laminectomy for lumbar spinal stenosis: a prospective study. 基于最小临床重要差异（MCID）分析的腰椎管狭窄单节段与双节段椎板切除术：一项前瞻性研究。

Medicinski Glasnik Pub Date : 2026-02-27 DOI: 10.17392/2034-23-01

Emir Begagić, Hakija Bečulić, Fahrudin Alić, Anes Mašović, Goran Lakičević, Lemana Buljubašić, Muhamed Haračić

{"title":"Minimal clinically important difference (MCID)-based analysis of single-versus two-level laminectomy for lumbar spinal stenosis: a prospective study.","authors":"Emir Begagić, Hakija Bečulić, Fahrudin Alić, Anes Mašović, Goran Lakičević, Lemana Buljubašić, Muhamed Haračić","doi":"10.17392/2034-23-01","DOIUrl":"https://doi.org/10.17392/2034-23-01","url":null,"abstract":"Aim: To compare outcomes and minimal clinically important differences (MCID) between single-level laminectomy (SLL) and two-level laminectomy (TLL) for lumbar spinal stenosis (LSS).Methods: This prospective study included 119 patients with confirmed LSS who underwent SLL or TLL at Cantonal Hospital Zenica from January 2018 to January 2025. Assessments were performed preoperatively and at 1 and 6 months postoperatively using the Oswestry Disability Index (ODI), Swiss Spinal Stenosis Questionnaire (SSSQ), and Visual Analogue Scale (VAS) for back and leg pain, along with evaluation of motor, sensory, and urinary function. MCID values were used to assess meaningful improvement.Results: At six months, SLL patients had lower ODI (15.0 vs. 18.0, p = 0.006), VAS-LB (3.0 vs. 5.0, p < 0.001), and SSSQ scores (17.2 vs. 21.6, p < 0.001) than TLL patients. Motor deficits (14.8% vs. 35.5%, p = 0.019) and urinary dysfunction at 1 month (5.7% vs. 22.6%, p = 0.013) were less frequent in SLL. More SLL patients achieved MCID for ODI (80.7% vs. 58.1%, p = 0.024) and SSSQ (73.9% vs. 48.4%, p = 0.017) at 6 months, with TLL patients 28% and 34% less likely to reach MCID for ODI and SSSQ, respectively. No significant differences were found preoperatively or at 1 month.Conclusion: The study suggests that SLL and TLL have comparable outcomes, with a slight tendency toward better functional improvement and fewer deficits after SLL.","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"23 1","pages":"167-172"},"PeriodicalIF":0.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147787812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of 3D printing on vascular surgery training and preoperative planning. 3D打印对血管手术培训和术前规划的影响。

Medicinski Glasnik Pub Date : 2026-02-27 DOI: 10.17392/1975-23-01

Haris Vukas, Samra Kadić-Vukas, Sumeja Ćatić, Ruvejda Dizdarević, Farah Dedović, Nail Šehić, Merim Jusufbegović

{"title":"Impact of 3D printing on vascular surgery training and preoperative planning.","authors":"Haris Vukas, Samra Kadić-Vukas, Sumeja Ćatić, Ruvejda Dizdarević, Farah Dedović, Nail Šehić, Merim Jusufbegović","doi":"10.17392/1975-23-01","DOIUrl":"https://doi.org/10.17392/1975-23-01","url":null,"abstract":"Aim: To investigate the impact of three-dimensional (3D) printing technology on vascular surgery, focusing on its role in preoperative planning and surgical training.Methods: A systematic review was conducted of studies published between 2017 and 2024 that evaluated 3D printing in vascular surgery. Databases searched included MEDLINE and CENTRAL. Eligible studies reported applications of 3D printing in preoperative planning, simulation, or surgical education.Results: Analysis of relevant studies revealed that 3D-printed vascular models improved surgical precision, reduced fluoroscopy time, enhanced technical skill acquisition, and increased trainees’ confidence. Models based on computed-tomography angiography data provided accurate, patient-specific anatomy for classic or endovascular aortic aneurysm repair and other vascular procedures.Conclusion: 3D printing significantly enhances vascular-surgery training and preoperative preparation by providing realistic, patient-specific simulations that improve both technical competence and surgical outcomes.","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"23 1","pages":"139-144"},"PeriodicalIF":0.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147788363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0