Medicinski Glasnik最新文献

{"title":"First trimester placental growth factor and uterine artery pulsatility index in the prediction of preeclampsia in high-risk pregnancy.","authors":"Jasmin Hodžić, Bedrana Muračević, Ajna Gračić, Hana Štimjanin Hodžić, Ema Bajgorić Škrgo","doi":"10.17392/1864-22-01","DOIUrl":"https://doi.org/10.17392/1864-22-01","url":null,"abstract":"<p><strong>Aim: </strong>To identify the most effective screening method for preeclampsia by evaluating the predictive significance of measuring serum placental growth factor (PlGF) concentration and using Doppler ultrasound assessments of uterine artery blood flow during the first trimester in high-risk pregnancies as predictors of preeclampsia.</p><p><strong>Methods: </strong>A prospective screening study involving 173 high-risk pregnant women for preeclampsia, between 11 + 0 and 13 + 6 weeks of gestation was conducted. Women were divided into two groups based on pregnancy outcome: a control group of 158 pregnant women who remained normotensive, and a group of 15 high-risk pregnant women who developed symptoms of preeclampsia during pregnancy. Serum PlGF concentration using a quantitative enzyme-linked immunosorbent assay was determined.</p><p><strong>Results: </strong>PlGF level was significantly reduced in women who later developed preeclampsia (14.06 pg/mL) compared to controls (37.46 pg/mL). The uterine artery pulsatility index (UtA-PI) was significantly increased in the preeclamptic group (1.73) compared to the control group (1.44). For screening preeclampsia using the combination of PlGF and UtA-PI, the estimated detection rates were 66.67% at the fixed false-positive rate (FPR) of 5% and 73.33% at the FPR of 10%. The best screening results were obtained using regression models including maternal characteristics PlGF, and UtA-PI, yielding estimated detection rates of 73.33% at the FPR of 5% and 86.67% at the FPR of 10%, respectively.</p><p><strong>Conclusion: </strong>Placental growth factor level, in conjunction with uterine artery pulsatility index during the first trimester was a valuable and accurate biomarker for predicting preeclampsia in high-risk pregnancies. When integrated with comprehensive medical history, these markers enhance the assessment of preeclampsia risk.</p>","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"22 1","pages":"71-77"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143701993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of a novel cost-effective suspension arthroplasty technique compared to traditional trapeziectomy with abductor pollicis longus arthroplasty Once Looped Around (OLA)/Once Looped Inside (OLI) in basal thumb arthritis.","authors":"Giuseppe Parrone, Adriano Cannella, Giulio Fioravanti Cinci, Matthew Charles Giordano, Arturo Militerno, Andrea De Matthaeis, Ludovico Caruso, Rocco De Vitis","doi":"10.17392/1880-22-01","DOIUrl":"https://doi.org/10.17392/1880-22-01","url":null,"abstract":"<p><strong>Aim: </strong>Trapeziometacarpal (TMC) joint osteoarthritis is a common source of wrist pain, predominantly affecting women aged 45 to 70 years. While traditional surgical options like trapeziectomy with abductor pollicis longus (APL) arthroplasty are effective, their limitations in advanced disease stages have led to the exploration of alternative techniques. This study compares the clinical outcomes of conventional trapeziectomy with APL arthroplasty to a novel personalized suspensory arthroplasty technique.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 150 patients with Stage III-IV TMC osteoarthritis who underwent either the conventional APL arthroplasty (n=65) or the novel suspensory arthroplasty (n=85) in the period between 2015 and 2018. Outcomes were assessed using the Numeric Pain Rating Scale (NPRS), Disabilities of the Arm, Shoulder, and Hand (DASH) scores, thumb range of motion, grip strength, and patient satisfaction. Statistical analyses included t-test, χ2 test, and repeated measures ANOVA.</p><p><strong>Results: </strong>Both surgical groups demonstrated significant pain reduction and functional improvement postoperatively. The novel technique resulted in lower NPRS and DASH scores, greater thumb metacarpophalangeal joint flexion-extension, and higher patient satisfaction compared to the traditional method. The prevalence of complications, particularly flexor carpi radialis (FCR) tendinitis, was also lower with the novel technique. Radiographic assessments indicated stable joint positions postoperatively in both groups.</p><p><strong>Conclusion: </strong>The novel personalized suspensory arthroplasty technique offers superior clinical outcomes compared to traditional APL arthroplasty, with enhanced pain management, improved function, and reduced complications. This approach represents a cost-effective and minimally invasive alternative for advanced TMC osteoarthritis, leading to better patient satisfaction and faster recovery.</p>","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"22 1","pages":"97-103"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The influence of high doses of vitamin C on functional recovery and postoperative pain in patients with trochanteric fracture after intramedullary nailing during a three-month follow-up: a pilot study.","authors":"Mirza Sivro, Đemil Omerović, Faruk Lazović, Adnan Papović","doi":"10.17392/1887-22-01","DOIUrl":"https://doi.org/10.17392/1887-22-01","url":null,"abstract":"<p><strong>Aim: </strong>To determine the effects of high peri- and postoperative doses of vitamin C administration on severity of pain in postoperative period and functional outcome of the patients with trochanteric fracture treated with intramedullary nailing during a three-month follow-up.</p><p><strong>Methods: </strong>A prospective, randomized, pilot study included 56 patients who were randomly divided into vitamin C (intervention) and control groups. In the intervention group, patients received vitamin C perioperatively by an intravenous route for 2 days, and oral vitamin C for 38 days postoperatively. Baseline characteristics, postoperative metamizole consumption, Visual Analogue Scale (VAS) score, Harris Hip Score (HHS) value, and the prevalence of complications were evaluated in both groups.</p><p><strong>Results: </strong>No significant differences were noted between the groups regarding age, gender, length of hospitalization, and distribution in fracture type. Postoperative metamizole consumption was notably higher in the control group compared to the vitamin C group (p=0.006). Postoperative VAS score was higher in the control group (p< 0.05). No significant differences in HHS values were detected between the groups at 6 and 12 weeks postoperatively (p=0.655 and p=0.755, respectively). The group variable significantly contributed to VAS score, and age and gender variables significantly contributed to HHS value.</p><p><strong>Conclusion: </strong>A significant reduction of subjective pain levels and lower analgesic consumption was found in patients who received vitamin C, suggesting that it should be considered as an adjuvant agent for analgesia in patients with hip fracture.</p>","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"22 1","pages":"121-126"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of age and body mass index on dual-energy X-ray absorptiometry scan results in postmenopausal women.","authors":"Halil Ćorović, Nusret Salkica, Naida Omerović Ćorović, Šejla Cerić, Selma Agić-Bilalagić, Amra Skopljak-Beganović, Enis Tinjak","doi":"10.17392/1870-22-01","DOIUrl":"https://doi.org/10.17392/1870-22-01","url":null,"abstract":"<p><strong>Aim: </strong>To analyse the impact of age and body mass index (BMI) on dual-energy X-ray absorptiometry (DXA) scan results in postmenopausal women.</p><p><strong>Methods: </strong>The study included 100 postmenopausal women who underwent the DXA procedure, out of which 50 had a normal BMI and 50 were overweight/obese. Data that were examined included age, BMI, T-score of the lumbar region and the femoral neck, as well as bone mineral density (BMD). Correlation results were presented as Pearson's correlation coefficient (r).</p><p><strong>Results: </strong>The T2-score and BMD2 were significantly lower in older patients compared to younger ones (p=0.008 and p=0.007, respectively). Post hoc test results showed that the T2-score and BMD2 were significantly lower in patients ≥71 years of age compared to patients ≤59 years of age (p=0.006 and p=0.005, respectively). Also, T1- and T2-scores, as well as BMD1 and BMD2, were significantly higher in overweight/obese patients (p< 0.001 and p=0.003; p< 0.001 and p=0.002, respectively). The correlation between BMI and the T1-score was moderate (r=0.429), between BMI and the T2-score weak (r=0.348), between BMI and BMD1 moderate (r=0.431), and between BMI and BMD2 weak (r=0.344).</p><p><strong>Conclusion: </strong>Our study showed that both age and BMI are important factors affecting DXA procedures and should be taken into account with each postmenopausal woman individually in everyday practice.</p>","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"22 1","pages":"78-82"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143701939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inhibitory effect of magnetic aqueous extract of Syzygium aromaticum L on two types of oral pathogenic bacteria.","authors":"Wafaa Sabri Eid, Saba Abdul Salam Hamid Al-Sultan, Rana Ibrahim Al-Sabaawi","doi":"10.17392/1883-22-01","DOIUrl":"https://doi.org/10.17392/1883-22-01","url":null,"abstract":"<p><strong>Aim: </strong>Magnetic fields affect all living things, which is why they are the subject of extensive research around the world. The aim of this study was to investigate the effects of different levels of static magnetic field on chemical behaviours of aqueous extract of Syzygium aromaticum L and their effect on selective oral pathogenic bacteria.</p><p><strong>Methods: </strong>This study utilized locally manufactured dipolar static magnetic fields with strengths between 1200 and 3200 Gauss, measured by a Sylocimol Residence magnetizer. Gram positive G (+) Streptococcus viridans and G negative (G-) Porphyromonas gingivalis strains were used in studies on the antimicrobial properties of S. aromaticum extract. Tests were carried out using the clove essential component (eugenol) and its functionalized extract to evaluate various bacterial inhibitions and establish whether there is a synergistic effect between the extract and subjected to the magnetic field.</p><p><strong>Results: </strong>Polyphenol extraction increased with eugenol content. The analytical method's reliability was confirmed by chromatograms of eugenol and eugenol acetate standards, demonstrating good separation of compounds. The selectivity of the method was guaranteed by the purity index of the eugenol and eugenol acetate peaks. The aqueous extract of S. aromaticum showed magnetic properties. The extract showed antimicrobial activity against two bacterial strains. Cell viability changed at different magnetic field intensities, and the inhibition zone for P. gingivalis increased significantly due to prolonged exposure.</p><p><strong>Conclusion: </strong>The magnetized extract inhibits both G (+) and G (-) bacteria when combined with clove extract.</p>","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"22 1","pages":"132-137"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factor analysis and predictive model development for problematic internet gaming disorder occurrence.","authors":"Andrian Fajar Kusumadewi, Raihan Hananto, Arrum Putri Amalia, Muhammad Dicky Hertanto, Hermanuaji Sihageng, Muhammad Jordan Diandraputra","doi":"10.17392/1844-22-01","DOIUrl":"https://doi.org/10.17392/1844-22-01","url":null,"abstract":"<p><strong>Aim: </strong>To examine several aspects, such as sociodemographic, psychological, personality, and parenting characteristics, that may contribute to the occurrence of problematic internet gaming disorder (PIGD) in Yogyakarta, Indonesia. Additionally, the study intends to create a model that can accurately predict people who are at high risk of developing PIGD.</p><p><strong>Methods: </strong>A cross-sectional study was conducted on 350 participants aged 15-25 years in Yogyakarta. The data were gathered through the use of a questionnaire that consisted of demographic measures: the Internet Gaming Disorder Scale-Short Form (IGDS9-SF), the Depression Anxiety Stress Scale (DASS-21), the Big Five Inventory (BFI), and the Parenting Style Questionnaire. Multiple logistic regression was utilized for data analysis in order to identify relevant risk factors and construct a risk prediction model.</p><p><strong>Results: </strong>The study revealed that certain sociodemographic characteristics (male and student), psychological factors (depression, anxiety, and stress), personality traits (high neuroticism, low conscientiousness), and authoritarian parenting style were all significant predictors of the occurrence of PIGD. These characteristics led to the creation of the risk prediction model, which demonstrated strong performance with an area under the curve (AUC) of 0.85 (95% CI 0.80-0.90).</p><p><strong>Conclusion: </strong>Multifaceted issue and variety of risk factors influence PIGD. This study's risk prediction model can effectively identify individuals at a heightened risk of developing PIGD. This allows for early and targeted preventative and treatment interventions to be implemented.</p>","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"22 1","pages":"166-172"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Which accessible clinical features and laboratory findings might predict methotrexate success in children with juvenile idiopathic arthritis in Bosnia and Herzegovina?","authors":"Adisa Čengić, Velma Selmanović, Sniježana Hasanbegović, Hamza Izeta, Lamija Zečević, Nejra Džananović","doi":"10.17392/1882-22-01","DOIUrl":"https://doi.org/10.17392/1882-22-01","url":null,"abstract":"<p><strong>Aim: </strong>To determine whether demographic data, clinical features, and laboratory variables at disease onset can predict the response to methotrexate in juvenile idiopathic arthritis (JIA) patients.</p><p><strong>Methods: </strong>A cohort of 143 newly diagnosed JIA patients initially treated with methotrexate was enrolled in this study. Demographic, clinical, and laboratory parameters were analysed using univariate and multivariate logistic regression to identify predictors of response to methotrexate. The variables included erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), platelets, IgA, IgG, the number of active joints and age at disease onset. Treatment response was assessed at six months, with patients classified as responders (those who achieved clinically inactive disease according to the American College of Rheumatology - ACR criteria) or non-responders.</p><p><strong>Results: </strong>Poor response to methotrexate was associated with the number of active joints (p=0.0001; OR=2.7), baseline levels of CRP (p=0.044; OR=1.138), IgA (p=0.004; OR=2.159), and platelet count (p=0.01; OR=1.05). IgG level (P=0.236) did not correlate with the treatment response.</p><p><strong>Conclusion: </strong>We identified widely available and clinically acceptable biomarkers that can be utilized as predictive indicators of response to methotrexate in JIA patients.</p>","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"22 1","pages":"48-52"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation of vitamin D serum level and quality of life in asthma patients.","authors":"Dženan Halilović, Jasmina Nurkić, Senahid Trnačević, Midhat Nurkić, Eldina Halilović, Ekrema Mujarić","doi":"10.17392/1861-22-01","DOIUrl":"https://doi.org/10.17392/1861-22-01","url":null,"abstract":"<p><strong>Aim: </strong>Moderate to severe asthma patients with sufficient and insufficient vitamin D serum level, respectively, were assessed with quality of life questionnaires before and after treatment with vitamin D added to their standard asthma treatment.</p><p><strong>Methods: </strong>Patients with moderate to severe asthma have been divided into two groups based on a serum level of vitamin D as sufficient or insufficient level of vitamin D, respectively. During 12 months, a total of 120 patients with sufficient level of vitamin D as well as 120 patients with insufficient level were given treatment with 2000 IU vitamin D for a three-month period. Quality of life of all patients was assessed by Asthma Control Test (ACT), Asthma Quality of Life (AQOL) and the physician's assessment expressed through the Global Evaluation of Treatment Effectiveness (GETE), which were performed before and after the treatment with Vitamin D.</p><p><strong>Results: </strong>Values of ACT and AQOL were higher after the treatment with vitamin D in both groups of patients. Values of GETE were lower after the treatment with vitamin D in both groups. All assessed components, psychological, physical, as well as the subjective feeling of control of the disease assessed by treating physicians, showed improvement after treatment.</p><p><strong>Conclusion: </strong>Adding vitamin D in the treatment regimen of moderate to severe asthma patients improves quality of life and general asthma treatment effectiveness.</p>","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"22 1","pages":"38-42"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypoxia-conditioned mesenchymal stem cells (MSC) exosomes attenuate ultraviolet-B (UVB)-mediated malondialdehyde (MDA) and matrix metalloproteinase-1 (MMP)-1 upregulation in collagen loss models.","authors":"Jessica Angelina, Agung Putra, Setyo Trisnadi, Dedy Hermansyah, Eko Setiawan, Titiek Sumarawati, Nur Dina Amalina","doi":"10.17392/1923-22-01","DOIUrl":"https://doi.org/10.17392/1923-22-01","url":null,"abstract":"<p><strong>Aim: </strong>To investigate the effects of exosome-derived human mesenchymal stem cells (EH-MSCs) on matrix metalloproteinase-1 (MMP)-1 and malondialdehyde (MDA) levels in ultraviolet-B (UVB)-irradiated Wistar rats.</p><p><strong>Methods: </strong>The study used a post-test-only control group design with randomized allocation. Thirty rats were exposed to UVB radiation (302 nm, 150 mJ/cm&sup2;) for 8 minutes, five times a week over two weeks. Five groups were established: a healthy control (G1), a negative control (G2), a positive control that received a 200 μL subcutaneous injection of hyaluronic acid (HA) (G3), a treatment group 1 that received a 200 μL subcutaneous injection of exosome-derived EH-MSCs (G4), and a treatment group 2 that received a 300 μL subcutaneous injection of EH-MSCs (G5). An ELISA was used to quantify the levels of MDA and MMP-1.</p><p><strong>Results: </strong>A significant reduction in the mean level of MDA in groups G4 (368.33 ± 59.67) and G5 (329.33 ± 82.06) was noted when compared to the negative control group G2 (686.58 &plusmn; 119.01) (p< 0.05). Similarly, MMP-1 showed a significant decrease in mean levels for G4 (0.08 ± 0.04) and G5 (0.07 ± 0.04) compared to G2 (0.33 ± 0.06) (p< 0.05).</p><p><strong>Conclusion: </strong>These findings suggest that EH-MSCs have potent antioxidant and antiinflammatory properties, mitigating UVB-induced skin damage by reducing oxidative stress markers.</p>","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"22 1","pages":"9-14"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of ActiPatch in the management and prevention of pillar pain following open carpal tunnel release surgery in weight-bearing hand of elderly patients: an observational study.","authors":"Giulia Sassara, Adriano Cannella, Ludovico Caruso, Giuseppe Taccardo, Marco Passiatore, Arturo Militerno, Maurizio Marinangeli, Rocco De Vitis","doi":"10.17392/1787-22-01","DOIUrl":"https://doi.org/10.17392/1787-22-01","url":null,"abstract":"<p><strong>Aim: </strong>To confirm the effectiveness of the ActiPatch device in treating and preventing pillar pain following open carpal tunnel release surgery.</p><p><strong>Methods: </strong>Ten elderly patients with pillar pain after carpal tunnel release surgery were treated with ActiPatch for seven days. When these patients underwent surgery on the opposite hand, they were pre-emptively treated with ActiPatch to prevent pillar pain. Pain was measured using the Visual Analog Scale (VAS), functionality was assessed using the Quick Disability of the Arm, Shoulder and Hand (QuickDASH) and Michigan Hand Questionnaire (MHQ) scoring systems, and patient satisfaction was evaluated.</p><p><strong>Results: </strong>All patients showed an improvement in pain level and functional capacity after using ActiPatch for pillar pain management. Additionally, none of the patients experienced pillar pain during the subsequent preventive phase.</p><p><strong>Conclusion: </strong>The use of ActiPatch proves to be a viable and effective approach for managing and preventing pillar pain in elderly patients with weight-bearing hands who have undergone carpal tunnel release surgery.</p>","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"22 1","pages":"115-120"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}