Journal of Sexual Medicine最新文献

{"title":"Comparative study of vancomycin/gentamicin versus 0.05% chlorhexidine gluconate solution dip and irrigation in hydrophilic coated penile implants.","authors":"Edward Karpman, Ryan Griggs, Carolyn Twomey, Gerard D Henry","doi":"10.1093/jsxmed/qdaf142","DOIUrl":"10.1093/jsxmed/qdaf142","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":"1521-1522"},"PeriodicalIF":3.3,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Known limitations and shared prioritization of sexual wellbeing: Response to Letter to the Editor.","authors":"","doi":"10.1093/jsxmed/qdaf158","DOIUrl":"10.1093/jsxmed/qdaf158","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":"1535"},"PeriodicalIF":3.3,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144486835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of sexual dysfunction among women with primary Sjögren's syndrome using a Female Sexual Function Index: a systematic review and meta-analysis.","authors":"Settimio D'Andrea, Antonio Vinci, Luca Navarini, Andrea Sansone, Annalisa Marino, Dorian Bardhi, Alessandra Bruno, Francesco Rosiello, Camilla Lombardo, Edoardo Agostini, Fabio Ingravalle, Susanna Gentili, Massimo Maurici, Antonella Berardicurti, Emmanuele A Jannini, Roberto Giacomelli, Onorina Berardicurti","doi":"10.1093/jsxmed/qdaf110","DOIUrl":"10.1093/jsxmed/qdaf110","url":null,"abstract":"<p><strong>Background: </strong>Only a few studies have assessed sexual dysfunction in women with primary Sjögren's syndrome (pSS).</p><p><strong>Aim: </strong>We aimed to confirm the higher prevalence of sexual dysfunction in these women and identify the most impaired domain of sexual function and the risk factors associated with it.</p><p><strong>Methods: </strong>We conducted a systematic review and meta-analysis to investigate the risk of sexual dysfunction in women with pSS according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. The study protocol has been registered in the \"PROSPERO international prospective register of systematic reviews\" with the registration number CRD42022298525.</p><p><strong>Outcomes: </strong>We aimed to compare sexual dysfunction among women with pSS compared to healthy subjects and which domain of the Female Sexual Function Index (FSFI) was most impaired.</p><p><strong>Results: </strong>In the analysis involving 16 studies, pSS is associated with 5-fold higher odds of reporting sexual dysfunction compared to the control group. Additionally, differences in FSFI scores between pSS and healthy controls were found to be statistically significant. All FSFI item sub-scores were affected by pSS more than the control group.</p><p><strong>Clinical implications: </strong>Sexual dysfunction is common in pSS and needs to be evaluated in all women with pSS.</p><p><strong>Strengths and limitations: </strong>This is the first meta-analysis that emphasized that sexual dysfunction in women with pSS should be evaluated regardless vaginal dryness. Nevertheless, caution is required when interpreting results due to the poor quality of the selected studies.</p><p><strong>Conclusion: </strong>The sexual dysfunction was a common issue in pSS with various causes and should be addressed by healthcare providers.</p>","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":"1399-1408"},"PeriodicalIF":3.3,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are some forms of delayed/inhibited ejaculation more intractable than others? Establishing delayed ejaculation subtypes based on severity of symptomology during partnered sex and masturbation.","authors":"David L Rowland, Sean M McNabney, Zsuzsanna Kövi, Krisztina Hevesi","doi":"10.1093/jsxmed/qdaf105","DOIUrl":"10.1093/jsxmed/qdaf105","url":null,"abstract":"<p><strong>Background: </strong>Men with delayed ejaculation (DE) do not represent a homogenous group, yet only a handful of studies have investigated the subtypes, etiology, and significant covariates of this sexual dysfunction.</p><p><strong>Aim: </strong>To identify differences in sexual functioning/responsivity and sexual behavior between DE subtypes characterized by men who experience symptomology during both partnered sex and masturbation (DE-ALLSEX group) vs men who experience symptomology only during partnered sex (DE-PARTSEX group).</p><p><strong>Method: </strong>After categorizing men into subtypes, groups were compared on variables related to demographics, sexual history, sexual response and functioning, preferred sexual activities during partnered sex and masturbation, and perceived causes of/attributions for their DE problem. Using logistic regression, a set of non-collinear differentiating variables was then used to predict DE-ALLSEX vs DE-PARTSEX group membership.</p><p><strong>Results: </strong>Relative to the DE-PARTSEX group, higher age, higher medication use, having multiple partners, and lower affinity for and pleasure during masturbatory activity predicted DE-ALLSEX group membership. Lower perceived penile sensitivity during masturbation, greater engagement in insertive anal intercourse, and perceived insufficient levels of masturbatory arousal also characterized this group. The strongest predictors of group membership were age and capacity to reach/frequency of orgasm during masturbation, with arousal level during masturbation and likelihood of engaging in penetrative anal sex also distinguishing between the two groups.</p><p><strong>Clinical translation: </strong>Although the relationship between masturbation activities and subtype membership is most likely bidirectional, the pervasiveness of masturbation activities as group-differentiating factors suggests avenues of clinical exploration in men presenting with DE symptomology.</p><p><strong>Strengths and limitations: </strong>This is the first study to attempt to understand and differentiate DE-ALLSEX and DE-PARTSEX subgroups, with a number of factors emerging as significant. However, cause-effect relationships between covariates and group membership remain elusive, and a larger sample size would have enabled investigation of a select group of DE men having only the most severe symptomology.</p><p><strong>Conclusion: </strong>Factors related to more pervasive problems with DE that affect ejaculatory capacity during both partnered and solo sex include medical, relational, arousal-related, and behavioral (masturbation and partnered sex) variables. Such factors represent potential discussion points during intake and treatment for men experiencing problems reaching ejaculation.</p>","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":"1363-1372"},"PeriodicalIF":3.3,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144276553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Are patients undergoing intralesional collagenase Clostridium histolyticum injection therapy for Peyronie's disease compliant? A 7-year analysis from a tertiary care men's health center.","authors":"","doi":"10.1093/jsxmed/qdaf152","DOIUrl":"10.1093/jsxmed/qdaf152","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":"1534"},"PeriodicalIF":3.3,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144259346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient perspectives on phalloplasty: a social media sentiment analysis.","authors":"Joyce J Zhu, Payton Kotlarz, Carson Bair, Jenna Stoehr, Brielle Weinstein","doi":"10.1093/jsxmed/qdaf141","DOIUrl":"10.1093/jsxmed/qdaf141","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":"1528-1530"},"PeriodicalIF":3.3,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sexual satisfaction and dysfunction in transgender adults following puberty suppression treatment during adolescence.","authors":"Isabelle S van der Meulen, Marijn Arnoldussen, Anna I R van der Miesen, Sabine E Hannema, Thomas D Steensma, Annelou L C de Vries, Baudewijntje P C Kreukels","doi":"10.1093/jsxmed/qdaf095","DOIUrl":"10.1093/jsxmed/qdaf095","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Sexual satisfaction and dysfunction in transgender and gender-diverse (TGD) individuals following treatment with puberty suppression (PS) have not yet been studied and remain a topic of clinical and academic concerns.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Aim: &lt;/strong&gt;This study explores the long-term effects of (early) PS treatment on sexual satisfaction and dysfunction in TGD individuals.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;This retrospective cohort study included 50 transmasculine and 20 transfeminine individuals treated with PS and gender-affirming hormones (GAH). Fifty-seven percent underwent genital gender-affirming surgery. All gender-related medical treatment (GRMT) was performed at the Center of Expertise on Gender Dysphoria in Amsterdam, the Netherlands, between 1998 and 2011. PS treatment was, on average, initiated 14 years prior to study participation. Sexual experiences were assessed using a self-developed questionnaire at least 9 years after GAH and compared between early and late PS treatment groups. Findings were compared with data of a transgender cohort that started GRMT at an adult age.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Outcomes: &lt;/strong&gt;The primary outcomes included sexual satisfaction and various sexual dysfunctions, defined as the presence of a sexual problem accompanied by distress.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Sexual satisfaction was reported by 52% of transmasculine and 40% of transfeminine individuals, with similar outcomes between early and late PS groups. Among transmasculine individuals, 58% reported at least one sexual dysfunction, most commonly difficulty with initiating sexual contact (34%), with similar frequencies in PS groups. In transfeminine individuals, 50% experienced at least one sexual dysfunction, with difficulty achieving orgasm (35%) being most common, with similar reports across PS groups. The prevalence of sexual dysfunctions was comparable to that of transgender individuals who began GRMT in adulthood.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Clinical implications: &lt;/strong&gt;These findings enable healthcare professionals to provide accurate and personalized information regarding the anticipated effects of early endocrine GRMT.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Strengths and limitations: &lt;/strong&gt;This is the first study to assess sexual satisfaction and dysfunction in TGD individuals treated with early and late PS. The small sample size precluded inferential statistical analyses.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;In this study, the majority of transgender individuals treated with PS did not experience difficulties with desire, arousal, or achieving orgasm in adulthood. Outcomes were similar for early and late PS treatment and comparable to previous findings in those who started GRMT in adulthood. Sexual satisfaction is comparable to the general population. These results may alleviate concerns about long-term effects on sexual satisfaction and dysfunction in TGD individuals who do not undergo (full) endogenous puberty. However, attention for sexual counseling","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":"1493-1503"},"PeriodicalIF":3.3,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144512770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on: Are some forms of delayed/inhibited ejaculation more intractable than others? Establishing delayed ejaculation subtypes based on severity of symptomology during partnered sex and masturbation.","authors":"Nikola Komlenac","doi":"10.1093/jsxmed/qdaf106","DOIUrl":"10.1093/jsxmed/qdaf106","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":"1309-1310"},"PeriodicalIF":3.3,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144276554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intermittent premature ejaculation: exploring an understudied phenomenon.","authors":"David L Rowland, Stanley E Althof, Philippe Cote-Leger","doi":"10.1093/jsxmed/qdaf113","DOIUrl":"10.1093/jsxmed/qdaf113","url":null,"abstract":"<p><strong>Background: </strong>Although the lifelong and acquired subtypes of premature ejaculation (PE) have long been acknowledged, other putative PE subtypes have garnered less consideration.</p><p><strong>Aim: </strong>This study aimed to describe a potentially unrecognized form of PE characterized by episodic or intermittent symptomology rather than regular, consistent symptomology.</p><p><strong>Methods: </strong>From an online sample of 409 men with PE, 31 identified as specifically having intermittent PE (IPE) rather than either lifelong PE (LPE) or acquired PE (APE). Data regarding PE symptomology-including lack of ejaculatory control, foreplay time and estimated ejaculation latencies (ELs) during PE episodes, foreplay time and estimated ELs during non-PE episodes, and other sexual characteristics-were collected to better describe and understand this group of men.</p><p><strong>Outcomes: </strong>Determination of sexual and ejaculatory response characteristics of men with IPE.</p><p><strong>Results: </strong>Men with IPE exhibited PE-typical responses during 40%-90% of their partnered sex episodes (mean ≈ 70%). Depending on the type of partnered sex, mean EL responses during PE episodes ranged from anteportal ejaculation to ~2 minutes, whereas mean EL responses during non-PE episodes ranged from ~3 to 6.5 minutes (P < .001). EL comparisons were also made across types of partnered sex and masturbation.</p><p><strong>Clinical implications: </strong>Some men exhibit PE-like symptoms, but do so only episodically or intermittently, a pattern that would technically prevent them from receiving treatment for PE according to most professional PE definitions.</p><p><strong>Strengths and limitations: </strong>This study is the first to detail the sexual and EL characteristics of men who experience PE intermittently. The limitations include issues regarding generalizability due to the relatively small sample size and the inherent bias possible in online studies about sexuality.</p><p><strong>Conclusion: </strong>Men with IPE show all the characteristics of men with LPE and APE, except in the consistency with which their symptoms are manifested. Such men would qualify for treatment under ICD-11 guidelines but not under other professionally based diagnostic criteria.</p>","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":"1373-1382"},"PeriodicalIF":3.3,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144250730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of diaphragmatic breathing exercises on individuals with premature ejaculation: a randomized controlled trial.","authors":"Umit Erkut, Dilber Karagozoglu Coskunsu, Kubra Erkut, Ali Veysel Ozden","doi":"10.1093/jsxmed/qdaf107","DOIUrl":"10.1093/jsxmed/qdaf107","url":null,"abstract":"<p><strong>Background: </strong>There are no standardized, evidence-based rehabilitation protocols for premature ejaculation (PE) which hinders effective management, the development of validated patient-reported outcomes, regulatory oversight, and the potential benefits of targeted interventions.</p><p><strong>Aim: </strong>To investigate the effect of diaphragmatic breathing exercises (DBE) on PE.</p><p><strong>Methods: </strong>Sixty-two participants with PE were randomly assigned to Group I (n = 31) or Group II (n = 31). Both groups received behavioral therapy (BT) and pelvic floor muscle training (PFMT) twice daily, three days a week, for eight weeks. Additionally, Group I recieved DBE twice daily, every day, for eight weeks. Intravaginal ejaculation latency time (IELT) was calculated with a stopwatch, at the end of the 8th week (post-treatment), and at 1-year follow-up. Pelvic floor muscle (PFM) strength and endurance were evaluated with ultrasound, and changes in the in the autonomic nerves system (ANS) parameters (including the root mean square of successive differences [RMSSD], proportion of NN50 [PNN50], low-frequency [LF] power, and high-frequency [HF] power) were evaluated with an Elite HRV device at pre-treatment and post-treatment by a blinded assessor.</p><p><strong>Outcomes: </strong>Primary outcome measurements were IELT, PFM strength and endurance, and changes in ANS paramaters.</p><p><strong>Results: </strong>The study was completed by 29 participants (mean age = 31.4 ± 6.5 years) in Group I and 30 (mean age = 31.3 ± 7.6 years) in Group II. At post-treatment, all outcome measures showed significant improvements in both groups (P <.001 for all). Compared to Gropu II, Group I showed significantly greater improvements in IELT(P=0.12), RMSDD (P<.001), PNN50 (P=.003), LF Power (P<.001), HF Power (P=.003), strength(P<.001), and endurance (P<.001). The median IELT increase from baseline to post-treatment was 283 seconds (range: 84-870; 900%) in Group I and 204 seconds (range: 44- 581; 690%) in Group II. While IELT declined significantly from post-treatment to 1-year follow-up in Group II, no statistically significant change was found in Group I.</p><p><strong>Clinical implications: </strong>The effect of DBE on the ANS may help regulate the ejaculatory reflex.</p><p><strong>Strengths and limitations: </strong>This is the first study to apply breathing exercises with BT and PFMT in men with PE. Limitations include the lack of exercise adherence records beyond 8 weeks and the estimation-based IELT measurement at baseline.</p><p><strong>Conclusion: </strong>Adding DBE, to BT and PFMT, yields better results in IELT (at 8 weeks and 1 year) and inreases PFM strength and endurance of PFM (at 8 weeks) in men with PE.</p>","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":"1422-1429"},"PeriodicalIF":3.3,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144530984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}