Journal of Sexual Medicine最新文献

{"title":"The impact of repetitive transcranial magnetic stimulation on female sexual arousal: a double-blind randomized controlled trial.","authors":"Reziya Dilixiati, Atila Abulizi, Xin Yin, Bin Xu, Zubeila Aihemaiti, Alapati Waili, Yuheng Fan, Diliyaer Dilixiati","doi":"10.1093/jsxmed/qdaf210","DOIUrl":"10.1093/jsxmed/qdaf210","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":"1785-1787"},"PeriodicalIF":3.3,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144876711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feminine figures: body image and physical characteristics in trans women after puberty suppression and subsequent estradiol therapy.","authors":"Lidewij S Boogers, Elena S F McDonnell, Annelou L C de Vries, Martin den Heijer, A S Paul van Trotsenburg, Sabine E Hannema, Chantal M Wiepjes","doi":"10.1093/jsxmed/qdaf206","DOIUrl":"10.1093/jsxmed/qdaf206","url":null,"abstract":"<p><strong>Background: </strong>Several studies have demonstrated an improvement in body image following gender-affirming hormone treatment (GAHT). In transgender girls, puberty suppression (PS) can be initiated before GAHT to prevent masculinization.</p><p><strong>Aim: </strong>The aim of this study is to assess body image, self-esteem and its determinants in trans women who received PS prior to GAHT.</p><p><strong>Methods: </strong>Forty-two trans women from a specialized gender clinic who initiated treatment <18 years were included in this cross-sectional study of whom 23 initiated PS in early puberty (Tanner stage G2-3), and 19 in late puberty (Tanner stage G4-5).</p><p><strong>Outcomes: </strong>Body Image Scale (BIS) scores, ranging from 1 (very satisfied) to 5 (very dissatisfied), Rosenberg self-esteem scores and anthropometric measurements were collected.</p><p><strong>Results: </strong>Participants were aged 20.1 ± 2.0 years and used GAHT for 4.2 ± 1.6 years. Mean total BIS score was 2.4 ± 0.6, indicating satisfaction. Height, BMI, foot length, and waist circumference correlated with corresponding BIS items, with smaller measurements being associated with higher satisfaction. Although total BIS scores were comparable between the early and late pubertal group (β0.3, 95% CI -0.05;0.7), most BIS items (24/27) scored lower in the early PS group, particularly voice (β-1.4, 95% CI -1.9;-0.8), Adam's apple (β-0.6 95% CI -1.2;0.001) and weight (β-1.1 95% CI -1.9;-0.4). Self-esteem correlated negatively with BIS scores (β-4.5, 95% CI -6.6;-2.5).</p><p><strong>Clinical implications: </strong>This study reports the potential benefits of PS, especially when initiated early in puberty, on body satisfaction, particularly with voice, and self-esteem in trans women. Clinicians should consider these outcomes when counseling on gender-affirming care and its timing, while also addressing many other factors potentially affecting body image and self-esteem, such as mental wellbeing, social support, quality of life, and other physical parameters like obesity.</p><p><strong>Strengths and limitations: </strong>Strengths include systematic data collection and the integration of objective and subjective variables. Limitations include a small sample size and potential selection bias due to exclusion criteria and non-participation, possibly affecting generalizability.</p><p><strong>Conclusion: </strong>Trans women using PS prior to GAHT are overall satisfied with their bodies and have average self-esteem. More feminine anthropometric measurements correspond to higher body satisfaction. Moreover, early start with PS is associated with higher satisfaction with voice, a characteristic strongly influenced by pubertal testosterone exposure.</p>","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":"1902-1909"},"PeriodicalIF":3.3,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144838443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Examining the prevalence of premature ejaculation as a three-dimensional construct of sexual dysfunction-a systematic review.","authors":"Mariella Opolony, Martin Rettenberger, Peer Briken, Daniel Turner","doi":"10.1093/jsxmed/qdaf187","DOIUrl":"10.1093/jsxmed/qdaf187","url":null,"abstract":"<p><strong>Background: </strong>Premature ejaculation is one of the most common types of sexual dysfunction among men. Frequently, a distinction was made between 4 premature ejaculation subtypes-lifelong, acquired, natural-variable, and subjective. Although somewhat outdated but still relevant in terms of etiological considerations, most researchers and clinicians in the past have summarized these subtypes under the terms psychogenic ejaculatory complaint (natural-variable and subjective premature ejaculation) and somatogenic impaired ejaculatory control (lifelong and acquired premature ejaculation). To date, there is no universally accepted subtype-specific therapy to treat premature ejaculation, as the exact etiology and prevalence of the individual premature ejaculation subtypes have not yet been sufficiently researched.</p><p><strong>Aim: </strong>The present systematic review aimed at examining the prevalence of premature ejaculation within the general population, as well as the prevalence of the premature ejaculation subtypes and the influence on prevalence rates of the diagnostic criteria being used.</p><p><strong>Methods: </strong>A total of 79 prevalence studies with 158 prevalence estimates from 33 countries, which were published in English or German, were systematically reviewed and compared. Studies from 1986 to August 2024 were included.</p><p><strong>Results: </strong>In total, the identified studies included a total sample size of 319 468 participants. The prevalence rate of premature ejaculation (Mw = 14.19%, SD = 15.87%) was strongly dependent on the research definition used. In terms of prevalence, psychogenic ejaculatory complaint appeared to dominate over somatogenic impaired ejaculatory control both within the general population (Mw = 18.22%, SD = 16.10% vs. Mw = 9.97%, SD = 14.06%) and among individuals with premature ejaculation (lifelong premature ejaculation: Mw = 11.67%, SD = 2.70%; acquired premature ejaculation: Mw = 18.96%, SD = 2.20%; natural-variable premature ejaculation: Mw = 43.89%, SD = 10.55%; subjective premature ejaculation: Mw = 24.79%, SD = 5.18%).</p><p><strong>Strengths and limitations: </strong>The main limitation of this review is the varying sample populations across studies. The heterogeneity of 158 premature ejaculation subtype-specific prevalence surveys from 79 studies prevented meta-analysis. A systematic review was chosen to use mean differences, allowing for continuous results and comparability. This design enabled the examination of several studies to identify population-based trends.</p><p><strong>Conclusion: </strong>Taking into account the review findings, it can be suggested that, in terms of a need-based treatment, the definition of premature ejaculation should be expanded to include the various forms and subtypes of premature ejaculation.</p>","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":"1718-1736"},"PeriodicalIF":3.3,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144838441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterizing transference risk to prepubertal children among candidates for transdermal testosterone therapy.","authors":"Marcelo Mass Lindenbaum, Samantha Thorogood, Luis F Novaes, Nicole Benfante, John P Mulhall, Jose M Flores","doi":"10.1093/jsxmed/qdaf193","DOIUrl":"10.1093/jsxmed/qdaf193","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":"1746-1747"},"PeriodicalIF":3.3,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144838511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Racial and ethnic disparities in vulvodynia treatment: a cross-sectional TriNetX database analysis.","authors":"Jessica Hinnes, Soowan Jeong, Mitali Sharma, Feyi Rufai, Rachel Pope, Lisa Bird","doi":"10.1093/jsxmed/qdaf214","DOIUrl":"10.1093/jsxmed/qdaf214","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":"1793-1795"},"PeriodicalIF":3.3,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144884262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of device-assisted circumcision on sexual quality of life in adult males: a systematic review.","authors":"Michalina Grudzińska, Jakub Gondek, Mateusz Czajkowski, Marcin Matuszewski","doi":"10.1093/jsxmed/qdaf191","DOIUrl":"10.1093/jsxmed/qdaf191","url":null,"abstract":"<p><strong>Introduction: </strong>Device-assisted circumcision has emerged as an alternative to traditional surgical methods, offering improved safety, efficiency, and cosmetic outcomes. While its clinical benefits are documented, on analyzing the literature, no comprehensive synthesis of the impact of device-assisted circumcision on sexual quality of life in adult men, including erectile function, ejaculation control, and overall satisfaction, has been found.</p><p><strong>Objectives: </strong>To synthesize the present literature regarding the effects of device-assisted circumcision on sexual quality of life among adult male populations.</p><p><strong>Methods: </strong>A systematic review following Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines was conducted. A systematic search of PubMed, EMBASE, Google Scholar, SCOPUS, EBSCO HOST, and the Cochrane Library was performed up to December 2024. The inclusion criteria encompassed prospective and retrospective clinical trials, cohort, cross-sectional, or case control, enrolling male patients ≥ 18 years old, regardless of ethnicity, marital status, and country of origin, who underwent device-assisted circumcision. The Newcastle-Ottawa Scale and Effective Public Health Practice Project Quality Assessment Tool were utilized for risk of bias assessment.</p><p><strong>Results: </strong>Literature searches identified 1643 records; 8 articles met the inclusion criteria, including 965 patients available for analysis. This cohort included 965 individuals circumcised using circumcision devices (PrePex [336]; ShangRing [297]; Alisklamp [267]; a novel disposable circumcision stitching instrument [51], and the adult circumcision template [14]). The mean age of participants ranged between 21.2 and 34.2 years. The circumcision devices either positively influence or maintain sexual satisfaction and functioning in males. Furthermore, the circumcision procedure has minimal adverse effects on erectile function, with some evidence suggesting potential improvement in the long term. Conflicting results were observed regarding sexual satisfaction and prolonged intercourse, with some studies reporting increased satisfaction and extended intercourse duration, while others found no significant changes in these aspects.</p><p><strong>Conclusion: </strong>The device-assisted circumcision demonstrates a positive influence on or maintains sexual quality of life in adult males, resulting in enhancements in erection quality, ejaculation control, duration of intercourse, and overall male satisfaction. The findings support its viability as a safe and efficacious alternative to traditional methods.</p>","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":"1871-1879"},"PeriodicalIF":3.3,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144838444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of genital self-image on sexual function: a systematic review.","authors":"Hermenson Gabriel Spíndola Barreto, Ana Carolinny Cruz Saraiva, Antônia Clarice de Sousa E Sousa, Guilherme Pertinni de Morais Gouveia","doi":"10.1093/jsxmed/qdaf194","DOIUrl":"10.1093/jsxmed/qdaf194","url":null,"abstract":"<p><strong>Introduction: </strong>Genital self-image (GSI) refers to a person's perception of their genitalia, whether positive or negative. In recent years, it has become increasingly common for individuals to report dissatisfaction and insecurity regarding the appearance of their bodies and genitals. This scenario has a negative impact on both physical and psychological health, in addition to negatively influencing sexual life.</p><p><strong>Objectives: </strong>To gather information on the relationship between GSI and sexual function and to determine whether there is an association between these two factors.</p><p><strong>Methodology: </strong>A Systematic Review was carried out in the following databases: CINAHL, Embase, MEDLINE, Open Science Journal, PeDro, PubMed, Scielo, Scopus, Science Direct, Springer Link, and OpenGrey. The research question was based on the PICO strategy: \"Is there an association between genital self-image and sexual function?\". Observational quantitative studies were included, regardless of language and publication data. Studies that did not include the terms \"Genital Self-Image\", \"Sexual Function\", and their synonyms and/or keywords in the title, duplicated studies or with low methodological quality were excluded.</p><p><strong>Results: </strong>Out of 1727 initially identified studies, 10 met the inclusion criteria. These studies involved 7448 participants (2280 men and 5168 women) aged 18 to 72 years. The analysis showed a consistent association between positive GSI and better sexual function, including increased desire and satisfaction. Conditions such as premature ejaculation and pelvic floor dysfunction negatively impacted both GSI and sexual performance, suggesting a reciprocal relationship between the GSI and sexual function. Despite the growing interest in genital cosmetic surgeries, studies did not show significant differences in sexual function between women who underwent these procedures and those who did not. Sociocultural factors, including dissatisfaction with genital size, were also found to negatively affect GSI and sexual well-being, especially among men.</p><p><strong>Conclusion: </strong>A positive GSI is associated with better sexual function, greater satisfaction and quality in intimate experiences. Despite this, methodological limitations and the lack of diversity in the populations studied restrict the generalization of the results. Future research should focus on addressing gaps, such as the lack of longitudinal studies and the underrepresentation of diverse populations.</p>","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":"1839-1847"},"PeriodicalIF":3.3,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144856993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Do the DSM-5 criteria actually reflect the clinical reality of female sexual dysfunctions?","authors":"Giovanni Pagnini, Elisa Fumarola, Gioele Salvatori, Davide Déttore","doi":"10.1093/jsxmed/qdaf027","DOIUrl":"10.1093/jsxmed/qdaf027","url":null,"abstract":"<p><strong>Background: </strong>The classification of female sexual dysfunctions (FSDs) remains inconsistent, with ongoing debate regarding the DSM-5's reliance on Basson's circular model to describe female sexual functioning.</p><p><strong>Aim: </strong>This study evaluates the extent to which the DSM-5 diagnostic criteria reflect clinical reality and explores alternative models that may better capture female sexual functioning.</p><p><strong>Methods: </strong>A cross-sectional study was conducted using a general population sample. Participants were classified into three non-clinical subgroups-Hypoactive Sexual Desire Disorder (HSDD), Female Sexual Arousal Disorder (FSAD), and Female Sexual Interest/Arousal Disorder (FSIAD)-based on DSM criteria. Descriptive and correlational analyses were performed using Pearson's correlation and chi-square tests to examine the relationships between diagnostic criteria and sexual response models.</p><p><strong>Outcomes: </strong>The study assessed the relationships between DSM-IV-TR and DSM-5 diagnostic criteria and their associations with different sexual response models. The variables of interest included measures of sexual desire and arousal, assessed through the Female Sexual Function Index (FSFI) and the Sexual Desire Inventory-2.</p><p><strong>Results: </strong>Findings revealed weak correlations between HSDD and FSAD criteria in DSM-IV-TR, with stronger negative correlations observed in DSM-5 criteria related to desire, arousal, and lubrication. Most women with sexual dysfunction identified with the circular model of female sexual functioning, although the linear model was predominant in the general population. Moderate associations were found between FSIAD and FSAD, whereas HSDD showed weaker associations with both.</p><p><strong>Clinical implications: </strong>The findings suggest that the DSM-5 FSIAD diagnosis may not effectively distinguish between desire and arousal-related symptoms. Sexual desire appears to be better represented as a spectrum rather than a categorical diagnosis. However, these conclusions should be interpreted with caution due to the limitations of cross-sectional observational data.</p><p><strong>Strengths & limitations: </strong>The size of the overall sample is a strength of the research; the lack of groups with clinician-made diagnoses and linguistic biases represented a limitation for the generalization of the results. Future studies should aim to analyze samples with clinician-made diagnoses.</p><p><strong>Conclusion: </strong>Female sexual functioning is complex and cannot be adequately captured by a single model. Future revisions of the DSM should consider conceptualizing sexual desire along a continuum to better reflect clinical reality and guide diagnostic processes.</p>","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":"1814-1826"},"PeriodicalIF":3.3,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144876709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitamin D deficiency and erectile dysfunction: emerging mechanisms and clinical challenges.","authors":"Fábio H Silva","doi":"10.1093/jsxmed/qdaf199","DOIUrl":"https://doi.org/10.1093/jsxmed/qdaf199","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":"22 10","pages":"1748-1749"},"PeriodicalIF":3.3,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145234026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sexual rumination and relationship satisfaction in Sexual Interest/Arousal Disorder: item-level multivariate analysis in partnered women with Sexual Interest/Arousal Disorder.","authors":"Orli S Hellerstein, Leo Arreaza, Renée E Woodward, Abhijit Chinchani, Todd S Woodward, Lori A Brotto","doi":"10.1093/jsxmed/qdaf255","DOIUrl":"https://doi.org/10.1093/jsxmed/qdaf255","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145228430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}