Atila Abulizi, Zubeila Aihemaiti, Reziya Dilixiati, Diliyaer Dilixiati, Li Xu
{"title":"Adjunctive repetitive transcranial magnetic stimulation for compulsive sexual behavior in a young adult with bipolar I disorder: a case report.","authors":"Atila Abulizi, Zubeila Aihemaiti, Reziya Dilixiati, Diliyaer Dilixiati, Li Xu","doi":"10.1093/jsxmed/qdaf258","DOIUrl":"https://doi.org/10.1093/jsxmed/qdaf258","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145187493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Navid Leelani, Nick W Lanpher, Anna Asif, Prajit Khooblall, Raevti Bole, Neel Parekh, Scott Lundy, Petar Bajic
{"title":"Socioeconomic factors impacting density of certified sex therapists in the United States.","authors":"Navid Leelani, Nick W Lanpher, Anna Asif, Prajit Khooblall, Raevti Bole, Neel Parekh, Scott Lundy, Petar Bajic","doi":"10.1093/jsxmed/qdaf239","DOIUrl":"https://doi.org/10.1093/jsxmed/qdaf239","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145180278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Livio Tarchi, Elena Mattesini, Jiska Ristori, Alessandra Daphne Fisher, Valdo Ricca, Giovanni Castellini
{"title":"Sexual desire in transgender and gender diverse individuals: a systematic review and meta-analysis.","authors":"Livio Tarchi, Elena Mattesini, Jiska Ristori, Alessandra Daphne Fisher, Valdo Ricca, Giovanni Castellini","doi":"10.1093/jsxmed/qdaf252","DOIUrl":"https://doi.org/10.1093/jsxmed/qdaf252","url":null,"abstract":"<p><strong>Introduction: </strong>Sexual health, including sexual desire in its two dimensions (solitary and dyadic), is a crucial component of overall well-being. In transgender and gender diverse (TGD) individuals, sexual desire may be further modulated by gender-affirming therapies (GATs). However, empirical appraisal of sexual desire across different domains in TGD individuals remains limited.</p><p><strong>Objectives: </strong>To compare sexual desire between TGD individuals and the general population, and to examine the associations between sexual desire, age, and GAT.</p><p><strong>Methods: </strong>A preregistered systematic review and meta-analysis, retrieving literature from three databases (PubMed, Scopus, and EMBASE). Six studies reporting population means by the Sexual Desire Inventory were finally included (TGD individuals, n = 1940). First, population means were derived within TGD individuals either assigned male (AMAB) or female (AFAB) at birth. Comparisons with reference means from the general population (n = 79.423) were made through Cohen's d. Associations with age, exposure to GAT, and duration of GAT were evaluated through meta-regression analyses.</p><p><strong>Results: </strong>AMAB (n = 1105) and AFAB (n = 835) TGD individuals reported significantly lower levels of sexual desire compared to the general population (solitary: Cohen's d = -0.53 to -0.57; dyadic: d = -0.76 to -1.27; total: d = -0.35 to -0.53; all P < .001). Solitary sexual desire was not significantly associated with age (β = 0.178, P = .587) or GAT (β = 10.168, P = .303). In contrast, dyadic sexual desire and total sexual desire were positively associated with exposure to GAT (dyadic: β = 30.201, P < .001; total: β = 42.823, P < .001). Older TGD individuals reported lower dyadic sexual desire (β = -0.404, P = .033) and were less likely to report increases in dyadic or total sexual desire following GAT (interaction terms, dyadic: β = -0.601, P = .014; total: β = -0.946, P < .001). No significant difference was found in sexual desire between AMAB and AFAB TGD individuals (solitary: β = -0.068, P = .962; dyadic: β = -3.186, P = .360; total: β = -5.505, P = .402).</p><p><strong>Conclusion: </strong>TGD individuals exhibit reduced sexual desire compared to the general population, particularly dyadic sexual desire. Dyadic sexual desire was also the domain most influenced by GAT. Current results suggest that older age may impede reaching the full benefits associated with GAT. These findings highlight the importance of addressing relational aspects of sexuality and age-specific needs in transgender health care.</p>","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145180305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
James M Jones, David W Barham, Martin S Gross, Chrystal Chang, Muhammed Hammad, Daniel Swerdloff, Jake Miller, Charles Loeb, Robert Andrianne, Arthur L Burnett, Kelli Gross, Georgios Hatzichristodoulou, James M Hotaling, Tung-Chin Hsieh, Lawrence C Jenkins, Adam Jones, Aaron C Lentz, Vaibhav Modgil, Daniar Osmonov, Sung H Park, Ian Pearce, Paul Perito, Hossein Sadeghi-Nejad, Maxime Sempels, Alfredo Suarez-Sarmiento, Jay Simhan, Koenraad van Renterghem, Jonathan Nicholas Warner, Matthew Ziegelmann, Faysal A Yafi, On Behalf Of The Pump Prosthetic Urology Multi-Institutional Partnership Collaborators
{"title":"Predictors of intraoperative complications in men undergoing inflatable penile prosthesis placement.","authors":"James M Jones, David W Barham, Martin S Gross, Chrystal Chang, Muhammed Hammad, Daniel Swerdloff, Jake Miller, Charles Loeb, Robert Andrianne, Arthur L Burnett, Kelli Gross, Georgios Hatzichristodoulou, James M Hotaling, Tung-Chin Hsieh, Lawrence C Jenkins, Adam Jones, Aaron C Lentz, Vaibhav Modgil, Daniar Osmonov, Sung H Park, Ian Pearce, Paul Perito, Hossein Sadeghi-Nejad, Maxime Sempels, Alfredo Suarez-Sarmiento, Jay Simhan, Koenraad van Renterghem, Jonathan Nicholas Warner, Matthew Ziegelmann, Faysal A Yafi, On Behalf Of The Pump Prosthetic Urology Multi-Institutional Partnership Collaborators","doi":"10.1093/jsxmed/qdaf136","DOIUrl":"https://doi.org/10.1093/jsxmed/qdaf136","url":null,"abstract":"<p><strong>Background: </strong>Intracavernosal injection (ICI) therapy for erectile dysfunction (ED) and prostate cancer treatments all carry a risk of corporal fibrosis, potentially making placement of an inflatable penile prosthesis more difficult.</p><p><strong>Aim: </strong>To evaluate the association between history of ICI, history of prostate cancer treatment (prostatectomy, radiation) and complications of inflatable penile prosthesis (IPP) placement.</p><p><strong>Methods: </strong>A retrospective cohort study was performed of primary IPP cases from 2016 to 2021 across 16 institutions. Patients were stratified by development of intraoperative complications (crossover, corporal perforation, or urethral injury) and between-group differences in risk factors were assessed. Multivariable logistic regression was used to assess for predictors of intraoperative complications and postoperative infection.</p><p><strong>Outcomes: </strong>The primary outcome was intraoperative complications, and secondary outcome was implant infection.</p><p><strong>Results: </strong>A total of 2540 patients met inclusion criteria. Intraoperative complications occurred in 36 (1.4%) patients. On multivariable regression, a history of ICI, prostatectomy, and radiation were all significant predictors of intraoperative complications (OR 2.11, P = 0.03; OR 2.27, P = 0.03; OR 2.40, P = 0.04, respectively). Age, body mass index, diabetes, hypertension, vascular disease, smoking, and Peyronie's disease were not predictors of intraoperative complications. None of the variables were significant predictors of infection.</p><p><strong>Clinical implications: </strong>Prosthetic urologists should counsel patients that a history of ICI or prostate cancer treatment with radical prostatectomy and/or radiation are associated with an increased risk of intraoperative complications.</p><p><strong>Strengths and limitations: </strong>Strengths of this study include the utilization of a large, multicenter, international dataset. The study is limited by retrospective nature, a lack of granular data as to the type and duration of ICI therapy, and inherent selection bias in that all cases were performed by dedicated implant surgeons.</p><p><strong>Conclusion: </strong>In men undergoing IPP placement, a history of ICI, a history of radical prostatectomy, and a history of radiation are all independently associated with increased risk of intraoperative complications.</p>","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145151642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Baptiste Sauterey, Clémence Herrenschmidt, Maloù Lec'hvien, Anne Patsouris, Jonathan Allard
{"title":"Evaluation of sexual health management practices among general practitioners in Western France: a cross-sectional study.","authors":"Baptiste Sauterey, Clémence Herrenschmidt, Maloù Lec'hvien, Anne Patsouris, Jonathan Allard","doi":"10.1093/jsxmed/qdaf249","DOIUrl":"https://doi.org/10.1093/jsxmed/qdaf249","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
William Brant, Ryoko Sato, Sirikan Rojanasarot, Santosh Telang, Jeffrey Loh-Doyle, Vi Nguyen, Tung-Chin Hsieh
{"title":"Infection rates and risk factors following inflatable penile prosthetic implantation: an analysis of real-world hospital data.","authors":"William Brant, Ryoko Sato, Sirikan Rojanasarot, Santosh Telang, Jeffrey Loh-Doyle, Vi Nguyen, Tung-Chin Hsieh","doi":"10.1093/jsxmed/qdaf224","DOIUrl":"https://doi.org/10.1093/jsxmed/qdaf224","url":null,"abstract":"<p><strong>Background: </strong>Erectile dysfunction significantly affects quality of life, and while inflatable penile prosthesis (IPP) is a definitive treatment option, post-operative infections remain a concern, requiring better understanding of patient-level risk factors.</p><p><strong>Aim: </strong>This study sought to analyze infection rates following IPP and to identify risk factors associated with infection using real-world data.</p><p><strong>Methods: </strong>Retrospective analysis was performed among patients aged ≥18 who underwent IPP insertion between 2016 and 2022 in the U.S using the Premier PINC AI™ Healthcare Database. Cox proportional hazards regression was used for statistical analysis.</p><p><strong>Outcomes: </strong>The primary outcome was infection rate post-IPP over time; twelve known risk factors examined included: older age (≥75), smoking status, positive human immunodeficiency virus status, diabetes (Type 1 and 2, with and without comorbidities), history of pelvic radiation, history of urinary diversion, spinal cord injury, obesity, concomitant circumcision, and Peyronie's disease.</p><p><strong>Results: </strong>Among 18 475 males with IPP surgery, the overall infection rate post-IPP was 3.1% at a median follow-up of 3 years, with 2.5% occurring within the first 6 months. The infection rate at 3 years was significantly higher for patients with at least one risk factor compared to those without any (3.9% vs. 2.8%, HR 1.40 [95% CI 1.14, 1.72]). Patients with ≥3 risk factors had the highest infection rate (5.6% vs. 2.8%, HR 2.18 [95% CI 1.26, 3.75]). Among 12 risk factors analyzed, five were significantly and positively associated with infection rate: Type 2 diabetes with comorbidities (4.7% vs. 3.0%, HR 1.56 [95% CI: 1.14, 2.1.3]), Type 2 diabetes without comorbidities (4.3% vs. 3.0%, HR 1.38 [95% CI: 1.06, 1.79]), spinal cord injury (9.8% vs. 3.0%, HR 2.81 [95% CI: 1.33, 5.93]), obesity (5.2% vs. 3.0%, HR 1.74 [95% CI: 1.26, 2.41]), and concomitant circumcision (6.6% vs. 3.0%, HR 2.01 [95% CI: 1.04, 3.89]).</p><p><strong>Clinical implications: </strong>The overall rate of infection post-IPP was low, with most infections occurring within the first 6 months, particularly among higher risk patients, highlighting the importance of close early postoperative monitoring.</p><p><strong>Strengths & limitations: </strong>Strengths include the large patient population and data from diverse clinical settings. However, hospital claims data may lack granularity and may have coding errors/misclassifications.</p><p><strong>Conclusion: </strong>This large observational study confirmed the low rate of infection post-IPP overall and that certain risk factors such as Type 2 diabetes, spinal cord injury, obesity, and concomitant circumcision significantly increased its likelihood, suggesting that optimizing specific risk factors preoperatively could enhance outcomes and improve patient care.</p>","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Saachi Pawa, Andrew Shin, Siline Thai, Alexandra Berger Eberhardt, Martin Kathrins
{"title":"Pilot study of MED3000 in treatment of erectile dysfunction after bilateral nerve-sparing radical prostatectomy.","authors":"Saachi Pawa, Andrew Shin, Siline Thai, Alexandra Berger Eberhardt, Martin Kathrins","doi":"10.1093/jsxmed/qdaf247","DOIUrl":"https://doi.org/10.1093/jsxmed/qdaf247","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Frederik Borg Schweizer, Lærke Nathalie Riise Dalgaard, Christian Graugaard, Mikael Andersson, Morten Frisch
{"title":"Sexual health and behaviors in homosexual, bisexual and heterosexual Danes: baseline findings in the Project SEXUS cohort study.","authors":"Frederik Borg Schweizer, Lærke Nathalie Riise Dalgaard, Christian Graugaard, Mikael Andersson, Morten Frisch","doi":"10.1093/jsxmed/qdaf220","DOIUrl":"https://doi.org/10.1093/jsxmed/qdaf220","url":null,"abstract":"<p><strong>Background: </strong>Population-based studies on the sexual health and behaviors of sexual minorities are scarce.</p><p><strong>Aim: </strong>To assess and compare sexual health and behaviors among homosexual, bisexual, and heterosexual Danes.</p><p><strong>Methods: </strong>We analyzed questionnaire data from 59 838 participants age 15-89 in the Project SEXUS study, including 1577 homosexuals, 1500 bisexuals, and 56 761 heterosexuals. Sex-specific logistic regression analyses with heterosexuals as reference yielded demographically weighted, confounder-adjusted odds ratios (aORs) for measures of sexual health and behaviors.</p><p><strong>Outcomes: </strong>Study-specific and internationally validated sexual outcome measures.</p><p><strong>Results: </strong>Compared with heterosexuals, lesbians were less likely to have had sex with another person in the last year. In contrast, sex partner numbers and frequencies of masturbation and porn consumption were higher among gay and bisexual men and bisexual women. Premature ejaculation was less common among gays (aOR, 0.50; 95% CI, 0.32, 0.81) and bisexual men (aOR, 0.62; 95% CI, 0.41, 0.93), whereas erectile dysfunction was more common among gays in the last 4 weeks (IIEF-5 score ≤ 11) (aOR, 3.01; 95% CI, 1.42, 6.38) and among both gays (aOR, 2.88; 95% CI, 1.87, 4.43) and bisexuals (aOR, 1.91; 95% CI, 1.24, 2.92) in the last year. Also, gays more often reported orgasmic dysfunction (aOR, 1.80; 95% CI, 1.09, 2.99). Overall female sexual dysfunction (FSFI-6 score ≤ 19) was less common among lesbians (aOR, 0.63; 95% CI, 0.40, 0.98) and bisexuals (aOR, 0.65; 95% CI, 0.48, 0.89), although vaginal cramp dysfunction was more common in bisexuals (aOR, 2.16; 95% CI, 1.15, 4.06). Gay and bisexual men and bisexual women reported more sexual risk indicators, with particularly high odds of sexual victimization among gays (aOR, 5.74; 95% CI, 3.72, 8.85), bisexual men (aOR, 5.03; 95% CI, 3.36, 7.54), and bisexual women (aOR, 2.67; 95% CI, 2.25, 3.16). Finally, gay and bisexual men were more often dissatisfied with the appearance of their bodies and genitals.</p><p><strong>Clinical implications: </strong>Health professionals should be aware of the greater burden of sexual health challenges among gay men and bisexual individuals.</p><p><strong>Strengths and limitations: </strong>Strengths include the large size, broad coverage, and national representativeness of our study. Limitations include a modest response rate (34.6%), the potential for self-selection and information biases, and uncertain generalizability to other countries.</p><p><strong>Conclusion: </strong>In this Danish study, lesbians exhibited no unusual burden of sexual risk indicators, and sexual dysfunctions along with sexually transmitted infections were less common in this group. In contrast, gay men and bisexuals of both sexes reported significantly more risky sexual behaviors, sexual victimization, sexual dysfunctions, and other adverse outco","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Davy Benarroche, Ugo Pinar, Sébastien Beley, Morgan Roupret
{"title":"Efficacy of platelet-rich plasma injections protocol for patients with Peyronie's disease: a multicenter prospective cohort study.","authors":"Davy Benarroche, Ugo Pinar, Sébastien Beley, Morgan Roupret","doi":"10.1093/jsxmed/qdaf248","DOIUrl":"https://doi.org/10.1093/jsxmed/qdaf248","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giuseppe Basile, David Ralph, Shafi Wardak, Philippa Sangster, Nim Christopher, Wai Gin Lee
{"title":"Penoscrotal decompression should be considered for prolonged ischaemic priapism.","authors":"Giuseppe Basile, David Ralph, Shafi Wardak, Philippa Sangster, Nim Christopher, Wai Gin Lee","doi":"10.1093/jsxmed/qdaf229","DOIUrl":"https://doi.org/10.1093/jsxmed/qdaf229","url":null,"abstract":"<p><strong>Background: </strong>Prolonged ischemic priapism (PIP) is a clinically challenging scenario with a high rate of erectile dysfunction for cases lasting more than 48 h.</p><p><strong>Aim: </strong>To report surgical and functional outcomes of patients with PIP treated by penoscrotal decompression (PSD).</p><p><strong>Methods: </strong>Retrospective data analysis of patients with PIP who underwent PSD with a proximal penile shaft surgical incision compared to the original technique after failing first-line treatment between 2019 and 2024 in two tertiary referral centers.</p><p><strong>Outcomes: </strong>The primary objective was the rate of successful procedures defined as the resolution of pain and no priapism recurrence. Secondary objectives were perioperative surgical outcomes and sexual function according to International Index of Erectile Function-5 score and progression to penile prosthesis (PP). Treatment success and sexual outcomes were also reported according to time of presentation of PIP.</p><p><strong>Results: </strong>Overall, 22 (85%) and 4 (15%) patients underwent bilateral and unilateral PSD, respectively. The median duration of priapism was 47 (36.5-58.8) hours, with half of the patients treated after 48 h. Penoscrotal decompression was successful in 18 (69%) cases, with a higher success rate for bilateral procedures (73%). Immediate penile detumescence was observed in 96% of cases, while 92% had complete pain relief. Efficacy varied with timing, with better outcomes for procedures performed within 36 h. Two (8%) patients had postoperative complications. Overall, 21 patients had documented sexual function status (median interquartile range follow-up of 10.4 [5.5-28.3] months) with worse ED in those who failed PSD (57% vs. 38%, P = .6). Two out of 13 (15%) patients developed an infection after PP insertion requiring explantation, while 86% reported satisfactory erectile function with or without PP insertion.</p><p><strong>Clinical implications: </strong>The variation to the PSD technique herein described has several potential advantages. A penile shaft incision facilitates quicker and more convenient exposure of the corpora, making it accessible for general urologists experienced in penile fracture repair.</p><p><strong>Strengths and limitations: </strong>This is the series with the longest follow-up data on patients treated with PSD for PIP. Limitations are the retrospective design of the study and the small cohort considered due to the rarity of PIP.</p><p><strong>Conclusions: </strong>Penoscrotal decompression is an effective and safe alternative treatment for patients with PIP. Its efficacy remains time-dependent, particularly when performed within 36 h, with bilateral decompression achieving improved success rates.</p>","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145114540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}