Journal of Sexual Medicine最新文献

{"title":"Effectiveness of artificial intelligence chatbots in providing sexual health information: an exploratory study.","authors":"Himel Mondal, Saumya Mishra, Jaswant Jangra, Adesh Kumar Agrawal, Santanu Nath, Sujit Sarkhel","doi":"10.1093/jsxmed/qdag028","DOIUrl":"https://doi.org/10.1093/jsxmed/qdag028","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":"23 3","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146214801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Impact of operating room personnel density on aerobiome-related infection risk in penile implant surgery.","authors":"","doi":"10.1093/jsxmed/qdag045","DOIUrl":"https://doi.org/10.1093/jsxmed/qdag045","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":"23 3","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146159072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early clinical outcomes of the \"drain and retain\" maneuver in inflatable penile prosthesis revision surgery: a multi-institutional review.","authors":"Thairo A Pereira, Jacob Good, Jacob O Rust, David W Barham, Christabel Egemba, Martin S Gross, Muhammed Hammad, Tung-Chin Hsieh, Alex Huynh, Aaron C Lentz, Brent Nosé, Jay Simhan, Faysal Yafi, Helen L Bernie","doi":"10.1093/jsxmed/qdag024","DOIUrl":"https://doi.org/10.1093/jsxmed/qdag024","url":null,"abstract":"<p><strong>Background: </strong>Urologic prosthetic reservoirs (UPRs) can become firmly adherent to surrounding structures, making their removal during revision surgeries risky. Over the past decade, the \"drain and retain\" maneuver has been increasingly adopted to safely leave decommissioned UPRs in place. However, outcomes associated with this technique and its safety remains controversial, with ongoing debate in the literature.</p><p><strong>Aim: </strong>To evaluate the efficacy and safety of the \"drain and retain\" maneuver using a contemporary, retrospective multi-institutional cohort.</p><p><strong>Methods: </strong>We reviewed records of patients who underwent inflatable penile prosthesis surgery at seven high-volume penile implant centers in the United States between July 2016 and September 2024. We compared revision cases involving subtotal device removal with \"drain and retain\" to those with complete component removal and exchange. Cases involving explantation for infection or revisions that reused the original reservoir were excluded. Postoperative complications and infection rates were assessed and compared between groups.</p><p><strong>Outcomes: </strong>Rates of short-term postoperative infection, non-infectious adverse events, and complications related to retained reservoirs.</p><p><strong>Results: </strong>233 cases were included. Among those, 112 (48.1%) used the \"drain and retain\" technique, while 121 (51.9%) involved complete reservoir removal. The mean follow-up duration was 12.6 months. No complications were attributed to the retained reservoirs. There were no statistically significant differences between groups in postoperative infection rates (P = .940), device malfunction (P = .674), or symptomatic migration of the new UPR (P = .955).</p><p><strong>Clinical implications: </strong>In this retrospective series with short-term follow-up, decommissioning the reservoir during revision surgery appeared to be a safe approach in the absence of infection; however, these findings may not be reflective of longer-term outcomes.</p><p><strong>Strengths and limitations: </strong>The strengths of this study include its multi-institutional design and the largest original patient cohort reported to date. Limitations include the retrospective, non-randomized design, relatively short follow-up period, and potential attrition bias, as patients experiencing complications may have sought care elsewhere and were not captured in our database.</p><p><strong>Conclusions: </strong>Based on short-term data from a retrospective series, the \"drain and retain\" strategy was associated with early safety outcomes comparable to complete removal while avoiding retropubic dissection, though longer-term outcomes remain unknown.</p>","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":"23 3","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146167733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes of salvage procedures with malleable implants for penile prosthesis infections in the Veterans Affairs National Medical System: a real-world, multi-surgeon retrospective analysis over a decade.","authors":"Laura Angulo-Llanos, Max D Sandler, Nikolas B Howell, Adam Williams, Thomas A Masterson Iii","doi":"10.1093/jsxmed/qdag042","DOIUrl":"10.1093/jsxmed/qdag042","url":null,"abstract":"<p><strong>Background: </strong>Penile prosthesis infection is a serious complication that often requires device explanation, leading to corporal fibrosis, penile shortening, and significant patient distress.</p><p><strong>Aim: </strong>To evaluate long-term outcomes of salvage procedure outcomes using malleable penile prostheses (MP) after infected inflatable penile prosthesis (IPP) explantation within the United States Veterans Affairs (VA) healthcare system.</p><p><strong>Methods: </strong>We conducted a real-world, retrospective review using the VA Informatics and Computing Infrastructure to identify men ≥18 years who underwent salvage procedures for infected penile prostheses between January 2012 and January 2023. Demographics, comorbidities, surgical details, culture results, and postoperative outcomes were analyzed. Washout protocols were categorized as Mulcahy or non-Mulcahy. Reinfection, MP retention, and IPP conversion were assessed.</p><p><strong>Outcomes: </strong>The primary outcomes assessed were prosthesis reinfection, retention of the malleable implant, and subsequent elective conversion to an inflatable prosthesis.</p><p><strong>Results: </strong>A total of 76 patients underwent salvage procedures at 30 VA centers, with 61 (80.3%) receiving MP. Median age was 65 years, and 36% had diabetes mellitus. Reinfection occurred in 29.5% of cases, with a significantly higher rate among diabetics (45.5% vs. 20.5%, P = .0403). No significant difference in reinfection rates was found between Mulcahy and non-Mulcahy washout protocols. Among those without reinfection, 70% retained the MP, 28% underwent elective conversion to IPP, and 2% had device removal for non-infectious reasons. The majority of non-Mulcahy protocols included antiseptic and antibiotic combinations such as normal saline, gentamicin, betadine, hydrogen peroxide, and vancomycin.</p><p><strong>Clinical implications: </strong>These findings support malleable salvage as a definitive, low-morbidity treatment option for many patients, especially within a cost-independent system such as the VA.</p><p><strong>Strengths & limitations: </strong>This is the largest real-world, national multi-site analysis of MP salvage outcomes in a national healthcare system, with robust follow-up. Limitations include its retrospective design and variability in washout protocols across centers.</p><p><strong>Conclusion: </strong>Salvage with malleable prostheses is a safe and effective strategy following penile prosthesis infection, with high rates of long-term device retention and functional satisfaction.</p>","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":"23 3","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147318052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to Letter to Editor on \"Evaluation of sexual dysfunction among women with primary Sjögren's syndrome using a Female Sexual Function Index: a systematic review and meta-analysis\".","authors":"Andrea Sansone, D'Andrea Settimio, Berardicurti Onorina, Marino Annalisa, Giacomelli Roberto, Emanuele A Jannini","doi":"10.1093/jsxmed/qdag018","DOIUrl":"https://doi.org/10.1093/jsxmed/qdag018","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":"23 3","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146159077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Defining clinically relevant responses in erectile function: an SMSNA position statement.","authors":"Landon Trost, Faysal Yafi, Alan Shindel, Mohit Khera, Raymond C Rosen, Petar Bajic, Helen Bernie, Martin Gross, Johanna Hannan, Sevann Helo, Lawrence Jenkins Ii, Carol Podlasek, Daniel Watter, Matthew Ziegelmann, Tobias Köhler","doi":"10.1093/jsxmed/qdaf392","DOIUrl":"10.1093/jsxmed/qdaf392","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;To date, no scoring system has adequately defined clinical efficacy of erectile dysfunction (ED) therapies when evaluating differences between cohorts or in meta-analytic studies.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Aim: &lt;/strong&gt;To outline the minimal criteria required for any therapy to be considered clinically effective in the treatment of ED.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;An analytic review was performed of standardized ED questionnaires, with a particular emphasis placed on the International Index of Erectile Function, Erectile Function Domain (IIEF-EFD), and the minimally clinically important difference (MCID) concept. The data were used to create a societal position statement and recommendations on best practices within clinical trials to determine treatment efficacy.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Outcomes: &lt;/strong&gt;The SMSNA provided 6 key statements and recommendations to suggest best practices and define minimal thresholds for improvements required for an ED therapy to be considered clinically effective.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The IIEF-EFD currently represents the preferred standardized questionnaire to evaluate for changes in erectile function post-treatment and is the only questionnaire adequate to assess primary outcomes. To claim efficacy, investigational treatments must demonstrate MCID between cohorts (eg, 2-, 5-, or 7-point median improvements between groups among mild, moderate, or severe ED cohorts) in prospective, randomized, placebo-controlled, and adequately powered studies. In studies employing mixed-severity ED populations, a method of calculating an adjusted MCID was proposed based on statistical weighting principles. Similarly, a novel method for analyzing differences between cohorts in meta-analytic studies was presented to incorporate the concept of MCID. Based on these principles, the SMSNA would not support efficacy of a therapy based on statistical significance in a meta-analytic study alone. Similarly, studies claiming efficacy utilizing responder approaches (ie, statistically higher percentage of men achieving MCID between cohorts) would not be acceptable unless the median difference between groups on the IIEF-EFD achieved MCID.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Clinical implications: &lt;/strong&gt;The current position statement provides important, evidence-based data and scientific principles to help define what may be considered as an effective therapy in the treatment of ED. This framework provides a basis that decision-makers, clinicians, and patients may use to help differentiate clinically effective therapies.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Strengths & limitations: &lt;/strong&gt;The published literature is limited by a lack of validated instruments and data defining MCID for ED therapies between cohorts and with meta-analytic studies. The current position statement provides important guidance on these areas of ambiguity pending further, definitive data.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;The current position statement provides detailed guidance on k","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":"23 3","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147367144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of platelet-rich therapies versus placebo in the treatment of erectile dysfunction: an updated systematic review and meta-analysis of randomized controlled trials.","authors":"Lucas G C R de Amorim, Murilo Ribeiro Sanches, Thairo A Pereira, Fernando Cruvinel de Freitas, Augusto Barbosa Reis, Helen L Bernie","doi":"10.1093/jsxmed/qdag019","DOIUrl":"https://doi.org/10.1093/jsxmed/qdag019","url":null,"abstract":"<p><strong>Introduction: </strong>Platelet-rich therapies (PRTs), including platelet-rich plasma and platelet-rich fibrin matrix, have drawn attention as treatments for erectile dysfunction (ED). However, evidence regarding their effectiveness remains limited.</p><p><strong>Objectives: </strong>To determine the efficacy of PRTs in the treatment of ED.</p><p><strong>Methods: </strong>We performed a systematic search of PubMed, Embase, and Cochrane Library in April 2025 for studies comparing PRT with placebo in patients with ED. Pooled risk ratios, mean differences, and standardized mean differences with 95% CIs were calculated. We used the Grading of Recommendations Assessment, Development, and Evaluation tool to assess the certainty of evidence and strength of recommendations. The outcomes of interest were the mean change in the erectile function domain of the International Index of Erectile Function (IIEF) score, the rate of men achieving minimum clinically important difference (MCID) in the IIEF-EF score, peak systolic velocity (PSV), end diastolic velocity (EDV), and visual analogue scale (VAS) pain score after injection.</p><p><strong>Results: </strong>We included seven randomized controlled trials (RCTs) comprising 479 patients, of whom 239 (49.9%) were randomized to PRTs. There were no differences between PRTs and placebo in the combined IIEF score at 1, 3, and 6 months of follow-up. There was no difference between groups in terms of the rate of men achieving MCID in IIEF-EF at 1 month, and at 3 months. PRTs showed a significantly higher rate of men achieving MCID in IIEF-EF at 6 months; however, it is noteworthy that only 3 studies provided data for this outcome, which may limit the robustness and generalizability of this result, thus should be interpreted with caution. There were no differences between groups in the PSV, EDV, and VAS pain score after injection.</p><p><strong>Conclusion: </strong>This meta-analysis of RCTs provides low-to-moderate certainty evidence that PRTs do not confer superior efficacy over placebo in improving sexual function in men with ED. However, the small number of patients restricts the generalizability of our conclusions. Additional high-quality studies are required to clarify the clinical role of PRTs in the management of ED.</p>","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":"23 3","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146144537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between hormonally mediated vestibulodynia and persistent urogenital symptoms: a retrospective chart review.","authors":"Pranjal Agrawal, Aboubacar Kaba, Ryan Nasseri, Clemens An, Lindsey A Burnett, Maria Uloko","doi":"10.1093/jsxmed/qdag029","DOIUrl":"10.1093/jsxmed/qdag029","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":"23 3","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147277692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pattern of mechanical failure of inflatable penile prosthesis.","authors":"Yizhou Ruan, Ashley Baring, Christopher Love, Gideon Blecher","doi":"10.1093/jsxmed/qdag023","DOIUrl":"https://doi.org/10.1093/jsxmed/qdag023","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":"23 3","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146777031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Sensory-Empathic Responsiveness and Orgasmic hypothesis: empathic sensitivity and reduced ejaculatory latency.","authors":"Jaoudat Moussalli","doi":"10.1093/jsxmed/qdag031","DOIUrl":"https://doi.org/10.1093/jsxmed/qdag031","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":"23 3","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146214742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}