Journal of Sexual Medicine最新文献

{"title":"Efficacy of platelet-rich plasma injections protocol for patients with Peyronie's disease: a multicenter prospective cohort study.","authors":"Davy Benarroche, Ugo Pinar, Sébastien Beley, Morgan Roupret","doi":"10.1093/jsxmed/qdaf248","DOIUrl":"https://doi.org/10.1093/jsxmed/qdaf248","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Penoscrotal decompression should be considered for prolonged ischaemic priapism.","authors":"Giuseppe Basile, David Ralph, Shafi Wardak, Philippa Sangster, Nim Christopher, Wai Gin Lee","doi":"10.1093/jsxmed/qdaf229","DOIUrl":"https://doi.org/10.1093/jsxmed/qdaf229","url":null,"abstract":"<p><strong>Background: </strong>Prolonged ischemic priapism (PIP) is a clinically challenging scenario with a high rate of erectile dysfunction for cases lasting more than 48 h.</p><p><strong>Aim: </strong>To report surgical and functional outcomes of patients with PIP treated by penoscrotal decompression (PSD).</p><p><strong>Methods: </strong>Retrospective data analysis of patients with PIP who underwent PSD with a proximal penile shaft surgical incision compared to the original technique after failing first-line treatment between 2019 and 2024 in two tertiary referral centers.</p><p><strong>Outcomes: </strong>The primary objective was the rate of successful procedures defined as the resolution of pain and no priapism recurrence. Secondary objectives were perioperative surgical outcomes and sexual function according to International Index of Erectile Function-5 score and progression to penile prosthesis (PP). Treatment success and sexual outcomes were also reported according to time of presentation of PIP.</p><p><strong>Results: </strong>Overall, 22 (85%) and 4 (15%) patients underwent bilateral and unilateral PSD, respectively. The median duration of priapism was 47 (36.5-58.8) hours, with half of the patients treated after 48 h. Penoscrotal decompression was successful in 18 (69%) cases, with a higher success rate for bilateral procedures (73%). Immediate penile detumescence was observed in 96% of cases, while 92% had complete pain relief. Efficacy varied with timing, with better outcomes for procedures performed within 36 h. Two (8%) patients had postoperative complications. Overall, 21 patients had documented sexual function status (median interquartile range follow-up of 10.4 [5.5-28.3] months) with worse ED in those who failed PSD (57% vs. 38%, P = .6). Two out of 13 (15%) patients developed an infection after PP insertion requiring explantation, while 86% reported satisfactory erectile function with or without PP insertion.</p><p><strong>Clinical implications: </strong>The variation to the PSD technique herein described has several potential advantages. A penile shaft incision facilitates quicker and more convenient exposure of the corpora, making it accessible for general urologists experienced in penile fracture repair.</p><p><strong>Strengths and limitations: </strong>This is the series with the longest follow-up data on patients treated with PSD for PIP. Limitations are the retrospective design of the study and the small cohort considered due to the rarity of PIP.</p><p><strong>Conclusions: </strong>Penoscrotal decompression is an effective and safe alternative treatment for patients with PIP. Its efficacy remains time-dependent, particularly when performed within 36 h, with bilateral decompression achieving improved success rates.</p>","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145114540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What knowledge matters for women's sexual wellbeing? Validating a questionnaire measuring sexual knowledge using public and patient involvement.","authors":"M Sophie Grosse-Rueschkamp, Selina M Kronthaler, Laura T Legeland, Daniel Schulze, Klaus M Beier, Laura Hatzler","doi":"10.1093/jsxmed/qdaf209","DOIUrl":"https://doi.org/10.1093/jsxmed/qdaf209","url":null,"abstract":"<p><strong>Background: </strong>Sex education is a known protective factor for female sexual health. However, data on specific aspects of sexual knowledge linked to sexual wellbeing and validated measures are missing.</p><p><strong>Aim: </strong>This study aims to develop and validate a questionnaire measuring specific aspects of sexual knowledge and explore the interplay with sexual wellbeing.</p><p><strong>Methods: </strong>Public & Patient Involvement (PPI) was conducted to identify important aspects of sexual knowledge for sexual wellbeing resulting in a first item set, which was reviewed after a cross-sectional pilot study in cisgender women (N = 449). The respective items were subject to Exploratory Factor Analysis. For the main analysis, the resulting questionnaire was distributed in a cross-sectional survey alongside items on sources of sex education and validated questionnaires assessing aspects of sexual wellbeing. We performed Confirmatory Factor Analysis (CFA), Multi-Group-CFA, and Structural Equation Modeling (SEM) with a regression framework to analyze the data.</p><p><strong>Outcomes: </strong>The primary outcome was sexual knowledge represented by three constructs and the secondary outcomes were the aspects of sexual wellbeing such as sexual function, orgasm consistency, sexual desire, sexual self-esteem, and sexual communication.</p><p><strong>Results: </strong>PPI resulted in a questionnaire assessing the three constructs (i) experiential knowledge and agency, knowledge of (ii) factual genital knowledge, and (iii) factual anatomical and functional knowledge. Of the 2880 cisgender women included in the main analysis (mean age, 31.89 years; SD, 11.16 years), one-third were able to correctly name the clitoris and vulva, respectively. Construct validity and reliability were established. Experiential knowledge and agency showed a three-factor structure in the CFA and was associated with exploration of the own body and pornography use as sources of sex education. Its generalized factor predicted all aspects of sexual wellbeing in the SEM. While factual genital knowledge and factual anatomical and functional knowledge were not correlated with any aspect of sexual wellbeing, they were associated with consumption of non-pornographic information from the internet as sources of sex education.</p><p><strong>Clinical implications: </strong>The questionnaire can be used to measure lacks of sexual knowledge associated with poor sexual functioning.</p><p><strong>Strengths and limitations: </strong>Strengths include the PPI-based questionnaire development and a large sample size. Due to the study design no interpretations on causal effects of sexual knowledge on sexual wellbeing can be drawn. The results are limited to the population of cisgender women.</p><p><strong>Conclusion: </strong>Cisgender women show significant lack of knowledge in factual sexual knowledge. Only experiential knowledge and agency predicts aspects of sexual wellbeing.</p>","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145092975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Penile Doppler ultrasound for erectile dysfunction assessment. A review of the current guidelines.","authors":"Marcelo Garrido, Jose M Flores","doi":"10.1093/jsxmed/qdaf250","DOIUrl":"https://doi.org/10.1093/jsxmed/qdaf250","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145092971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of vulva nomograms and assessment of female genital self-image: does the size of labia minora really matter?","authors":"Alba Bartolomé, Cecilia Villalaín, Raquel Alarza, Yaiza García-Castro, Alberto Galindo, Álvaro Tejerizo","doi":"10.1093/jsxmed/qdaf243","DOIUrl":"https://doi.org/10.1093/jsxmed/qdaf243","url":null,"abstract":"<p><strong>Background: </strong>Labiaplasties have significantly increased, mainly because of aesthetic dissatisfaction, despite the lack of clear definitions for vulva dimensions.</p><p><strong>Aim: </strong>To develop nomograms of the different vulvar structures and secondly to assess their association with women's genital self-perception in our setting (teaching hospital in Spain).</p><p><strong>Methods: </strong>Prospective cross-sectional study including women >16 years old attending gynecological consults for non-aesthetic reasons without vulvar pathology. A sociodemographic survey, and the validated questionnaires Female Genital Self-image scale-Spanish (FGSIS-S) and Genital Appearance Satisfaction-Spanish (GAS-S) were administered prior to the measurement of the external genital structures (labia majora, labia minora, and clitoral hood) and assessment of phenotypical characteristics.</p><p><strong>Outcomes: </strong>Participants were stratified into three age groups (<30, 30-49, $ge$50 years) and the relationship between the widest labia minora and reported genital concern was analyzed using logistic regression; and its relationship with FGSIS-S and GAS-S scores through ordered logistic regression.</p><p><strong>Results: </strong>247 women aged 17-73 years old were included. Anatomy showed great variability. Vulva measurements (in mm) were (mean ± standard deviation): clitoral hood length 24 ± 9; and width 9 ± 3; labia minora width, right 19 ± 9, left 20 ± 8; and length, right 36 ± 13, left 41 ± 13. There was no significant association between the width of labia minora and the report of concern about genital appearance (P = 0.16), nor with FGSIS-S or GAS-S. We found a mild significant association between the length of the labia minora and women's report of concern (OR 1.02 (95% CI 1.00-1.04), P = 0.03); and with GAS-S (0.02 (95% CI 0.005-0.04)). After adjusting by age and parity, the length of the labia minora became non-statistically significant.</p><p><strong>Clinical implications: </strong>These references can help healthcare professionals educate patients about vulvar phenotypical diversity and provide better counselling, but they should be used cautiously to avoid medical pathologization when anatomy is not within the range described in studies.</p><p><strong>Strengths and limitations: </strong>We provide a comprehensive approach to self-perception of genital satisfaction including validated questionnaires and measurements of different structures. The main limitation is the relatively small sample size that did not allow for stratification into more age groups or ethnicity subclassification and a possible self-selection bias of women who attend gynecological consults.</p><p><strong>Conclusion: </strong>Nearly half of the women in gynecological consults reported concern about genital appearance, unrelated to labia minora width or other measurements after adjusting by age and parity.</p>","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145093003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Repair of inguinal hernia secondary to reservoir migration following penile prosthesis implantation: technique modification and case series.","authors":"Shadi Al-Bahri, Javereeya Abduljabbar, Muwafak A Salman, Abdalla AlHammadi, Fayez T Hammad","doi":"10.1093/jsxmed/qdaf246","DOIUrl":"https://doi.org/10.1093/jsxmed/qdaf246","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145092964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vagina transplantation in transfeminine individuals: insight into patient view and considerations.","authors":"Jayson J Sueters, Sharon M Wesselius, Tim C van de Grift, Freek A Groenman, Judith A F Huirne, Zeliha Guler","doi":"10.1093/jsxmed/qdaf244","DOIUrl":"https://doi.org/10.1093/jsxmed/qdaf244","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145092962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Y-V meatoplasty: a simple novel technique to correct meatal stenosis.","authors":"Michael Sennert, Mohammed Fawzy, Johannes Wirmer, Carsten Graumann, Ahmed T Hadidi","doi":"10.1093/jsxmed/qdaf236","DOIUrl":"https://doi.org/10.1093/jsxmed/qdaf236","url":null,"abstract":"<p><strong>Background: </strong>Meatal stenosis is a common complication following hypospadias repair. Dilatation or meatotomy is usually not effective and may result in recurrence of symptoms.</p><p><strong>Aim: </strong>To report our experience with Y-V meatoplasty, a simple novel technique to correct postoperative meatal stenosis after hypospadias surgery with up to 8 years of follow-up.</p><p><strong>Methods: </strong>A small inverted V skin flap is elevated with the angle at the tip of the meatus. Each limb is 3 to 5 mm long. A wedge of the narrow meatus underneath the flap is excised, creating a wide meatus. The tip of the inverted V is advanced distally and sutured to the angle inside the wide new meatus. The aim is to interrupt the ring suture line by introducing the V skin flap into the ring. This minimizes the chances of further ring contraction. The technique was used in 57 patients with symptomatic postoperative meatal stenosis from 2017 to 2024. The median age was 53 months (range, 17 months-44 years). Median follow-up was 4 years (range, 3 months-8 years).</p><p><strong>Outcomes: </strong>The Y-V technique helped to relieve the obstructive symptoms in the majority of patients (55 patients).</p><p><strong>Results: </strong>Fifty-two patients recovered well without further symptoms or problems. Three children complained of mild dysuria after surgery that disappeared within a month after surgery without additional intervention. Two patients (3.5%) early in the study required further surgery due to inadequate excision of the stenotic ring. There were no cases of postoperative urinary tract infections.</p><p><strong>Clinical implications: </strong>The Y-V technique may be used to help any patient with ring meatal stenosis.</p><p><strong>Strengths and limitations: </strong>This study describes a novel meatoplasty variant in a rather large patient collective with long follow-up to 8 years and in some patients without any discomforts. However, it is a single-center retrospective study, and 6 patients did not maintain follow-up more than 1 year.</p><p><strong>Conclusion: </strong>Y-V meatoplasty represents a simple effective technique to successfully correct postoperative ring meatal stenosis with a low complication rate of 3.5%.</p>","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145092914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes following discontinuation of chlorhexidine gluconate in inflatable penile prosthesis surgery: a return to antibiotics for irrigation and dip.","authors":"Milad Bonakdar Hashemi, Sevann Helo, Andres H Guillen Lozoya, Matthew J Ziegelmann, Tobias S Köhler","doi":"10.1093/jsxmed/qdaf223","DOIUrl":"https://doi.org/10.1093/jsxmed/qdaf223","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145092966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between dietary vitamin E intake and erectile dysfunction in adults: analyses of NHANES and Mendelian randomization.","authors":"Shishuai Duan, Jiajun Kan, Jing Zhao, Hongming Wu, Huisheng Yuan, Yuzhu Xiang","doi":"10.1093/jsxmed/qdaf242","DOIUrl":"https://doi.org/10.1093/jsxmed/qdaf242","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145092937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}