Journal of Sexual Medicine最新文献

{"title":"Female sexual dysfunction in China: challenges and perspectives.","authors":"Elena Colonnello, Chunlin Wang, Emmanuele A Jannini","doi":"10.1093/jsxmed/qdaf215","DOIUrl":"https://doi.org/10.1093/jsxmed/qdaf215","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":"22 10","pages":"1764-1765"},"PeriodicalIF":3.3,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145234090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subset of vulvodynia in pediatric and pre-puberal adolescents: an under-recognized problem.","authors":"Barbara Dionisi, Mattia Dominoni, Marianna F Pasquali, Manuela Torraca, Martina R Pano, Roberto Senatori, Barbara Gardella","doi":"10.1093/jsxmed/qdaf198","DOIUrl":"10.1093/jsxmed/qdaf198","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":"1791-1792"},"PeriodicalIF":3.3,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144838447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The investigation of penile hemodynamic profile and relevant hormones in erectile dysfunction patients with non-diabetic chronic kidney disease.","authors":"Jen-Hao Kuo, Chih-Yu Shen, Yi-Chia Hsieh, Yu-Chiao Lin, Chia-Min Liu, Hau-Chern Jan, Yin-Chien Ou, Yung-Ming Lin, Tsung-Yen Lin, Yu-Sheng Cheng","doi":"10.1093/jsxmed/qdaf211","DOIUrl":"10.1093/jsxmed/qdaf211","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":"1757-1758"},"PeriodicalIF":3.3,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144977785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improved health-related quality of life and gender congruence after gender-affirming mastectomy-a prospective cohort study.","authors":"Isak Gran, Alexander Kamali, Fredrik Granath, Louise Frisén, Ebba K Lindqvist, Cecilia Dhejne, Pehr Sommar, Helena Sackey","doi":"10.1093/jsxmed/qdaf203","DOIUrl":"10.1093/jsxmed/qdaf203","url":null,"abstract":"<p><strong>Background: </strong>Gender-affirming mastectomy (GAM) is the most common surgical treatment for transgender men and non-binary individuals.</p><p><strong>Aim: </strong>To prospectively investigate how GAM affects health-related quality of life (HRQoL) and gender congruence in transgender men and non-binary individuals.</p><p><strong>Methods: </strong>A prospective cohort study including 112 individuals with the diagnosis transsexualism or other gender identity disorder (F64.0 or F64.8 respectively, according to ICD-10) who underwent GAM at our hospital between 2016 and 2021. To measure HRQoL, gender appearance congruence and gender identity acceptance, the Short Form-36 Health Survey (SF-36) and the Transgender Congruence Scale (TCS) respectively, were distributed prior to surgery (baseline), and 12-36 months post-operatively. Paired t-tests were used to assess the difference in mean scores between these measure points and adjusted for multiple testing with Bonferroni correction.</p><p><strong>Outcomes: </strong>A statistically significant improvement was observed in TCS overall score and subscale appearance congruence, as well as the SF-36 domains related to emotional well-being, vitality and bodily pain.</p><p><strong>Results: </strong>The response rate was 92.0%. A statistically significant improvement was observed (P < .00625) in the SF-36 domains related to emotional well-being, as well as in the domains vitality and bodily pain, when comparing baseline with 12-36 months postoperatively. The overall TCS score as well as the subscale appearance congruence showed statistically significant improvement (P < .0167), whereas the gender identity acceptance subscale scores were relatively high at baseline and did not show a statistically significant change.</p><p><strong>Clinical implications: </strong>Gender-affirming mastectomy is a desirable procedure to reduce gender dysphoria and improve HRQoL in transgender men and non-binary individuals.</p><p><strong>Strengths and limitations: </strong>To our knowledge, this is one of the largest studies to prospectively examine the impact of GAM on HRQoL and gender congruence in transgender men and non-binary individuals. Additionally, the response rate was high, exceeding 90%.A limitation to our study is that the questionnaires used were not originally developed to evaluate effects on HRQoL, appearance congruence and gender identity acceptance after GAM specifically. Also, not all patients who underwent GAM during the study period were included, as some declined to participate.</p><p><strong>Conclusion: </strong>Gender-affirming mastectomy is associated with improved HRQoL and increased congruence between gender identity and appearance in transgender men and non-binary individuals.</p>","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":"1882-1890"},"PeriodicalIF":3.3,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144838445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Facial anthropometric considerations in facial feminization surgery: a systematic review.","authors":"Antoinette T Nguyen, Jonathan I Leckenby, Clinton Morrison","doi":"10.1093/jsxmed/qdaf204","DOIUrl":"10.1093/jsxmed/qdaf204","url":null,"abstract":"<p><strong>Background: </strong>Facial feminization surgery (FFS) is a key component of gender-affirming care, yet the field has historically been shaped by Eurocentric esthetic norms, with limited consideration of racial and ethnic differences in facial structure and sociocultural perceptions of femininity.</p><p><strong>Objective: </strong>To systematically evaluate existing literature on racial and ethnic considerations in FFS, including disparities in access, craniofacial anthropometric variability, gender perception, and postoperative outcomes.</p><p><strong>Methods: </strong>A systematic review was conducted following PRISMA 2020 guidelines and registered with PROSPERO. A comprehensive search of PubMed, Scopus, and Embase (through March 2025) identified studies assessing racial and ethnic variations in FFS access, surgical outcomes, craniofacial anthropometry, and gender perception. Studies were evaluated for risk of bias using the Newcastle-Ottawa Scale (NOS), the Joanna Briggs Institute (JBI) Checklist, and the CASP Qualitative Checklist. A narrative synthesis was performed due to heterogeneity in study designs and outcome measures.</p><p><strong>Results: </strong>Nine studies comprising 778 patients were included. Findings highlighted significant racial disparities in procedural selection, with African American, Asian, and Hispanic patients being less likely to undergo cranioplasty or rhinoplasty. Anthropometric studies revealed racial differences in nasolabial angle, chin dimensions, and mandibular flare. Social perception studies indicated an implicit whitening of femininity in FFS esthetics. However, race was not a significant predictor of revision rates or postoperative complications.</p><p><strong>Conclusion: </strong>There is a paucity of research on race and ethnicity in FFS. Future studies should integrate race-conscious surgical planning, assess long-term patient-reported outcomes, and address systemic barriers to equitable access.</p>","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":"1891-1901"},"PeriodicalIF":3.3,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144838442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The connections among childhood abuse, sexual compulsivity, and violent sexual behavior.","authors":"Lucas Naufal Macedo, Marcos Antonio Almeida-Santos, Marco de Tubino Scanavino","doi":"10.1093/jsxmed/qdaf202","DOIUrl":"10.1093/jsxmed/qdaf202","url":null,"abstract":"<p><strong>Background: </strong>Violent sexual behaviors (VSB) are rarely investigated in the clinical context of Compulsive Sexual Behavior (CSB). There is evidence that childhood traumas likely generate more emotional dysregulation, which seems to be associated with greater impulsivity and sexual compulsivity activation.</p><p><strong>Aim: </strong>We delineated a cross-sectional study with individuals with and without CSB to investigate if symptoms of impulsivity, sexual compulsivity, anxiety, and depression are associated with childhood abuse (CA) and VSB.</p><p><strong>Methods: </strong>We enrolled 364 (247 CSB and 117 controls) cisgender men who underwent psychiatric structured interview and answered self-responsive standardized measures. We built the Sexual Violence Factor (SVF) after a factorial analysis of the sexual violence subscale of the Compulsive Sexual Behavior Inventory-22, and used it as the outcome variable of VSB. We conducted a structural equation model (SEM).</p><p><strong>Outcomes: </strong>The evaluation of both direct and indirect effects of the construct Abuse on Violence, as well as the strength of associations between variables within a model demonstrating best-fit to the data.</p><p><strong>Results: </strong>The SEM analysis showed moderate association between CA and impulsivity (coef. = 0.37, P < 0.001), anxiety and depression (coef. = 0.61, P < 0.001), sexual compulsivity (coef. = 0.58, P < 0.001), and SVF in adulthood (coef. = 0.41, P = 0.01). However, sexual compulsivity was not associated with SVF.</p><p><strong>Implications: </strong>Impulsivity potentially associates with both CA and SVF, potentially implicating in more intensive clinical care for impulsive changes when a history of CA is present.</p><p><strong>Strengths and limitations: </strong>few women sought to the service, resulting in a sample comprised solely of men. Due to some missing data, the SEM analysis could not have all the participants. Additionally, the data should not be generalized once it is a convenience sample. Regarding the strengths, this study starts filling a gap of investigations of VSB in clinic samples of CSB individuals outside of a criminal setting. The use of the SEM allowed for a comprehensive examination of the relationships among key psychopathological factors (emotional dysregulation, impulsivity, sexual compulsivity), and trauma experiences with the VSB, helping to identify confounding factors.</p><p><strong>Conclusion: </strong>The SEM analysis provided a detailed assessment of our initial hypothesis, revealing that impulsivity seems to be a significant associating factor of VSB in individuals with CSB that suffered childhood maltreatment.</p>","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":"1848-1855"},"PeriodicalIF":3.3,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144838448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A lifespan perspective on lifelong premature ejaculation: unresolved issues and new insights.","authors":"Philippe Cote-Leger, Stanley E Althof, David L Rowland","doi":"10.1093/jsxmed/qdaf197","DOIUrl":"10.1093/jsxmed/qdaf197","url":null,"abstract":"<p><strong>Background: </strong>Despite the numerous studies dealing with lifelong premature ejaculation (LPE), significant issues remain unresolved, including the age of onset relative to sexual debut, its constancy or variation over the lifespan, how it is affected by foreplay, and whether it is altered by different types of partnered sexual activities and/or masturbation. Aim: To describe lifespan changes in PE symptomology in men with LPE.</p><p><strong>Method: </strong>Using a retrospective-current analysis, from an online sample of 409 men with PE, 160 identified as specifically having LPE. Data regarding PE symptomology-including lack of ejaculatory control, foreplay time and estimated ejaculation latencies (ELs) at sexual debut and currently, and other sexual characteristics-were collected to better describe and understand PE lifespan patterns in this group of men.</p><p><strong>Outcomes: </strong>Foreplay and EL comparisons between sexual debut and the present time, as well as EL comparisons across different types of sexual activities, including masturbation.</p><p><strong>Results: </strong>Men with LPE showed strong consistency in foreplay duration and ELs ever since their sexual debut. 77% indicated no change in their PE, 18.6% reported worsening of their PE, and 2% indicated improvement since sexual debut, with only the frequency of partnered sex showing any association with the above patterns. LPE men showed some variation in ELs across different types of partnered sexual activities, and also in comparison with masturbation.</p><p><strong>Clinical implications: </strong>Men with LPE show remarkable consistency in their short ELs with the passage of time and across different sexual activities; however, variation in EL does appear to be mildly-moderately linked to different kinds of sexual stimulation in some LPE men.</p><p><strong>Strengths and limitations: </strong>This study is the first of its kind to adopt a retrospective-current strategy to explore lifespan changes in PE symptomology in men with LPE. Limitations may include reliance on recall of events surrounding men's sexual debut, as well as the use of social media to recruit respondents, which likely results in age, education, and socioeconomic status bias.</p><p><strong>Conclusion: </strong>Men with LPE show typically normal foreplay duration, along with estimated ELs of 1-2 min, both of which are consistent over their lifespan. Mild to moderate variation in ELs was associated with specific types of sexual activity, including masturbation.</p>","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":"1737-1745"},"PeriodicalIF":3.3,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144838508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Circular grafting combined for length gain in men after penile implant surgery.","authors":"Michael West, Jose M Flores, John P Mulhall","doi":"10.1093/jsxmed/qdaf190","DOIUrl":"10.1093/jsxmed/qdaf190","url":null,"abstract":"<p><strong>Introduction: </strong>Acquired penile shortening has multiple possible causes, including Peyronie's disease, penile prosthesis (PP) removal, trauma, radical prostatectomy, and long-standing erectile dysfunction. If severe, it can preclude the ability to have intercourse. Multiple surgical techniques aimed at enhancing penile length have been described. Herein, we describe a circular grafting technique for penile lengthening in men with debilitating penile length loss.</p><p><strong>Aim: </strong>To describe the indications, technique, outcomes, and complications associated with circular grafting with PP insertion.</p><p><strong>Methods: </strong>We describe our preferred method for performing circular grafting with PP insertion.</p><p><strong>Main outcome measure: </strong>Penile length gain achieved after circular grafting.</p><p><strong>Results: </strong>Average penile length gain after circular grafting is 2.5 cm in our practice. This is similar to the length gain associated with other similar procedures.</p><p><strong>Conclusion: </strong>Circular grafting is a viable option to augment penile length in men with penile length loss precluding intercourse. Possible complications include changes in sensation, tissue necrosis, infection, and PP malfunction.</p>","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":"1856-1859"},"PeriodicalIF":3.3,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144838512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes of plication techniques for moderate-to-severe Peyronie's disease.","authors":"Pedro Caetano Edler Zandoná, Rubens Pedrenho Neto, José de Bessa, Plinio Moreira de Goes, Igor Valente Coimbra, Eduardo Zinoni Silva Pato, William Carlos Nahas, Jorge Hallak, Bruno Chiesa Gouveia Nascimento","doi":"10.1093/jsxmed/qdaf216","DOIUrl":"10.1093/jsxmed/qdaf216","url":null,"abstract":"","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":"1808-1809"},"PeriodicalIF":3.3,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144977752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between erectile dysfunction onset timing, online information seeking behavior, and International Index of Erectile Function-5 severity scores.","authors":"Hector Rodrigo Gonzalez-Carranza, Ricardo Ramón Tinoco-Betancourt, Luis Antonio Reyes-Vallejo","doi":"10.1093/jsxmed/qdaf218","DOIUrl":"10.1093/jsxmed/qdaf218","url":null,"abstract":"<p><strong>Background: </strong>The easy access to the Internet through smartphones leads to the immediate search for information when experiencing erectile dysfunction (ED) symptoms, and this can lead to late medical attention.</p><p><strong>Aim: </strong>This study assesses to identify the time between the onset of ED symptoms and the first time medical consultation and its correlation with searching for information on the Internet.</p><p><strong>Methods: </strong>Data were collected using validated questionnaires and clinical interviews.</p><p><strong>Outcomes: </strong>Search for information on the Internet, International Index of Erectile Function-5 severity score, time between onset of symptoms, and first time medical appointment were analyzed. Relations were stablished using t-test.</p><p><strong>Results: </strong>Among 202 men, the average time between the onset of symptoms and first time medical appointment was 30.7 months. There is a correlation between ED severity and the first time medical appointment (P < .01). There is a statistically significant relationship between time for first medical appointment and searching for information on the Internet (P < .01). Patients who look for information on the Internet take less time for a first time medical appointment, unless they have severe ED (29.2 vs. 33.12 months).</p><p><strong>Clinical implications: </strong>Medical information on the Internet should be trustworthy and lead the patients to attend medical consultation and diminish sexual dissatisfaction.</p><p><strong>Strengths and limitations: </strong>Strengths include demographic heterogeneity, knowing the characteristics of the information found on the Internet, and a robust methodology. Limitations include the cross-sectional design and the sample size.</p><p><strong>Conclusions: </strong>The availability of information on the Internet, often lacking scientific backing, has been identified as a factor contributing to delays in seeking professional care, with consequent risks to the patient's health. The significant delay observed in seeking medical consultation after the onset of ED suggests the existence of barriers that are not yet fully understood and warrant further in-depth study.</p>","PeriodicalId":51100,"journal":{"name":"Journal of Sexual Medicine","volume":" ","pages":"1759-1761"},"PeriodicalIF":3.3,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144977713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}