{"title":"Long-term risk of all-cause mortality and major adverse cardiovascular events in hip osteoarthritis patients after total hip replacement","authors":"Nai-Chen Shih MD, PhD , Han-Wei Yeh MD , Shun-Fa Yang PhD , Jing-Yang Huang PhD , Ping-Kun Tsai MD, PhD , Chao-Bin Yeh MD, PhD","doi":"10.1016/j.annepidem.2025.09.018","DOIUrl":"10.1016/j.annepidem.2025.09.018","url":null,"abstract":"<div><h3>Introduction</h3><div>To evaluate the long-term effects of total hip replacement (THR) on all-cause mortality and major adverse cardiovascular events (MACEs) among patients with hip osteoarthritis (OA).</div></div><div><h3>Methods</h3><div>A retrospective cohort study utilizing data from the TriNetX US Collaborative Network, a multicenter electronic health record database. We identified adult patients diagnosed with hip OA between January 1, 2012, and December 31, 2020. Propensity score matching (PSM) was employed to generate 16,893 matched pairs of patients who underwent THR and those who did not. Outcomes included all-cause mortality and incidence of MACEs, analyzed using Kaplan–Meier survival curves and Cox proportional hazards models. Subgroup analyses were conducted stratified by age, sex, race, and body mass index (BMI).</div></div><div><h3>Results</h3><div>Following PSM, patients receiving THR demonstrated a significantly 41 % lower risk of all-cause mortality (hazard ratio [HR], 0.59; 95 % confidence interval [CI], 0.54–0.64) and a 41 % lower risk of MACEs (HR, 0.59; 95 % CI, 0.56–0.62) compared with those not undergoing THR. Subgroup analysis revealed sex-based heterogeneity in mortality benefit (HR, 0.61; 95 % CI, 0.54–0.69 in males vs. HR, 0.75; 95 % CI, 0.66–0.87 in females). Age-stratified analyses for MACE risk showed a diminishing protective effect with increasing age (HR, 0.48 for 50–59 years; HR, 0.58 for 60–69 years; HR, 0.66 for 70–79 years).</div></div><div><h3>Conclusions</h3><div>Total hip replacement is associated with a substantial reduction in long-term all-cause mortality and cardiovascular events among patients with hip OA, corresponding to approximately 40 % lower risks compared with non-surgical patients. These associations appear to be modified by sex and age. The observed benefits may reflect improved mobility, enhanced physical activity, and better cardiovascular health following surgical intervention.</div></div>","PeriodicalId":50767,"journal":{"name":"Annals of Epidemiology","volume":"111 ","pages":"Pages 65-73"},"PeriodicalIF":3.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145151824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annals of EpidemiologyPub Date : 2025-11-01Epub Date: 2025-10-08DOI: 10.1016/j.annepidem.2025.10.009
Borja del Pozo Cruz PhD , Francisco Perales PhD , Marcin Straczkiewicz PhD , Marcos Matabuena PhD , Jesús del Pozo-Cruz PhD , Rubén López-Bueno PhD
{"title":"Unequal strides to longevity. The extra mile to health equity","authors":"Borja del Pozo Cruz PhD , Francisco Perales PhD , Marcin Straczkiewicz PhD , Marcos Matabuena PhD , Jesús del Pozo-Cruz PhD , Rubén López-Bueno PhD","doi":"10.1016/j.annepidem.2025.10.009","DOIUrl":"10.1016/j.annepidem.2025.10.009","url":null,"abstract":"<div><h3>Purpose</h3><div>To examine differences in all-cause mortality risk reductions associated with daily steps across socioeconomic strata.</div></div><div><h3>Methods</h3><div>Prospective cohort study using NHANES data (2011–2014) with a median follow-up of 5.9 years among 7032 U.S. adults aged 18–80 years. Exposure was accelerometer-measured daily steps categorized by socioeconomic status using the Ratio of Family Income to Poverty (RFIP; low <1.30, medium 1.30–1.84, high ≥1.85). Outcome was all-cause mortality determined via linkage to the National Death Index through December 2019. Cox proportional hazards models with restricted cubic splines and Relative Excess Risk due to Interaction (RERI) were applied.</div></div><div><h3>Results</h3><div>Over the follow-up, 452 participants died. Higher daily steps were associated with reduced mortality risk in all socioeconomic groups. However, socioeconomically advantaged individuals experienced greater risk reductions per 1000 daily steps compared to disadvantaged groups (RERI for low vs. high RFIP: –0.115, 95 % CI: –0.189, –0.042). Individuals with low RFIP required 1.2–2.3 times more steps to match the mortality benefits seen in high RFIP groups.</div></div><div><h3>Conclusions</h3><div>Socioeconomically disadvantaged populations may not benefit equally from daily steps. Addressing the factors contributing to this discrepancy will help maximize the health benefits of walking for all, thereby reducing overall health disparities.</div></div>","PeriodicalId":50767,"journal":{"name":"Annals of Epidemiology","volume":"111 ","pages":"Pages 117-119"},"PeriodicalIF":3.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145269416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annals of EpidemiologyPub Date : 2025-11-01Epub Date: 2025-10-08DOI: 10.1016/j.annepidem.2025.10.002
Biruk Beletew Abate , Berihun Assefa Dachew , Getinet Ayano , Kim Betts , Rosa Alati
{"title":"Prenatal depression comorbid with diabetes or hypertension and the risk of adverse neonatal outcomes: A systematic review and meta-analysis","authors":"Biruk Beletew Abate , Berihun Assefa Dachew , Getinet Ayano , Kim Betts , Rosa Alati","doi":"10.1016/j.annepidem.2025.10.002","DOIUrl":"10.1016/j.annepidem.2025.10.002","url":null,"abstract":"<div><h3>Purpose</h3><div>This systematic review and meta-analysis aim to synthesise evidence on the association between prenatal depression comorbid with diabetes and/or hypertension and adverse birth outcomes.</div></div><div><h3>Methods</h3><div>A comprehensive literature search was conducted across PubMed, Medline, Scopus, Web of Science, Embase, PsycINFO, and Google Scholar. Eligible studies assessed the effect of comorbid prenatal depression and diabetes or hypertension on obstetric or neonatal outcomes. Methodological quality was appraised using the Joanna Briggs Institute tool. Random-effects meta-analyses were conducted using inverse-variance weighting. Subgroup, sensitivity, and publication bias analyses were also performed.</div></div><div><h3>Results</h3><div>Fourteen studies, comprising over 11 million participants, were included. Prenatal depression comorbid with hypertension was significantly associated with increased risks of preterm birth (OR = 2.09; 95 % CI: 1.04–4.19), low birth weight (LBW) (OR = 2.08; 95 % CI: 1.07–4.07), and small for gestational age (SGA)(OR = 1.34; 95 % CI: 1.11–1.60). Additionally, comorbid prenatal depression and diabetes were associated with higher odds of cesarean section (CS) delivery (OR = 1.42; 95 % CI: 1.36–1.47).</div></div><div><h3>Conclusions</h3><div>The findings suggest that prenatal depression comorbid with gestational diabetes or hypertension may increase the risk of adverse birth outcomes, including preterm birth, LBW, SGA, and CS delivery. These findings underscore the need for early identification and targeted management of such comorbidities. Integrated treatment approaches that combine mental and physical healthcare may be essential to improve outcomes for both mothers and infants.</div></div>","PeriodicalId":50767,"journal":{"name":"Annals of Epidemiology","volume":"111 ","pages":"Pages 154-162"},"PeriodicalIF":3.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145276553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annals of EpidemiologyPub Date : 2025-11-01Epub Date: 2025-10-01DOI: 10.1016/j.annepidem.2025.09.022
Masanori Kuroki
{"title":"The rising predictive power of LGBT identity in mental health: An analysis of variable importance","authors":"Masanori Kuroki","doi":"10.1016/j.annepidem.2025.09.022","DOIUrl":"10.1016/j.annepidem.2025.09.022","url":null,"abstract":"<div><h3>Purpose</h3><div>To assess the changing predictive importance of lesbian, gay, bisexual, and transgender (LGBT) status on mental health outcomes between 2014 and 2023.</div></div><div><h3>Methods</h3><div>We utilized data from the Behavioral Risk Factor Surveillance System (BRFSS) and employed two ensemble methods—random forests and gradient boosting—as well as traditional logistic regression, to analyze the predictive power of various factors, including LGBT status, on frequent mental distress. Frequent mental distress was defined as experiencing poor mental health for 14 or more days during the previous 30 days.</div></div><div><h3>Results</h3><div>Our analysis revealed a significant and consistent increase in the predictive importance of LGBT status on frequent mental distress across all three modeling approaches. Specifically, LGBT status consistently rose from the 8th or 13th most important predictor in 2014 to the 3rd or 5th most important in 2023, depending on the model. This trend demonstrates that SOGI has become one of the most influential factors for predicting mental health challenges in recent years.</div></div><div><h3>Conclusions</h3><div>These findings highlight the growing importance of sexual orientation and gender identity (SOGI) as a risk factor for mental health challenges.</div></div>","PeriodicalId":50767,"journal":{"name":"Annals of Epidemiology","volume":"111 ","pages":"Pages 102-106"},"PeriodicalIF":3.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145226342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annals of EpidemiologyPub Date : 2025-11-01Epub Date: 2025-10-09DOI: 10.1016/j.annepidem.2025.09.024
Samuel Schildhauer , Lauren Linde , Stephanie Bertsch-Merbach , Gail L. Sondermeyer Cooksey , Christina Morales , Estela Saguar , April Hatada , Blanca Molinar , Debra A. Wadford , Seema Jain , Jake M. Pry , CalSRVSS County Collaborators
{"title":"Clinical presentation of seasonal respiratory viruses in California, May 2020–July 2022","authors":"Samuel Schildhauer , Lauren Linde , Stephanie Bertsch-Merbach , Gail L. Sondermeyer Cooksey , Christina Morales , Estela Saguar , April Hatada , Blanca Molinar , Debra A. Wadford , Seema Jain , Jake M. Pry , CalSRVSS County Collaborators","doi":"10.1016/j.annepidem.2025.09.024","DOIUrl":"10.1016/j.annepidem.2025.09.024","url":null,"abstract":"<div><h3>Purpose</h3><div>The coronavirus disease 2019 (COVID-19) pandemic caused disruptions in the transmission of seasonal respiratory viruses. COVID-19 is characterized by a range of non-specific symptoms, making it difficult to differentiate from other seasonal respiratory viruses. The goal of this analysis was to further understand trends in the circulation and differences in reported symptoms between respiratory pathogens during the COVID-19 pandemic.</div></div><div><h3>Methods</h3><div>From May 2020 to July 2022 a sentinel surveillance program collected data and respiratory specimens in outpatient settings across California and tested them for 19 respiratory viruses. Data were analyzed by identified respiratory pathogen to describe trends and clinical presentations. Multiple logistic regression was used to estimate odds of each respiratory pathogen by reported symptoms.</div></div><div><h3>Results</h3><div>We included results from 19,183 specimens, of which 8599 (44.8 %) tested positive for a pathogen, including 3742 (20.0 %) for SARS-CoV-2 and 3057 (15.9 %) for rhinovirus/enterovirus. Those reporting systemic symptoms had significantly higher adjusted odds of testing positive for influenza (aOR=9.2; 95 %CI, 6.7–13.1) or SARS-CoV-2 (aOR=2.4; 95 %CI, 2.2–2.6).</div></div><div><h3>Conclusions</h3><div>The variability in testing positive for a pathogen among people reporting different symptom profiles suggests a potential benefit of complete testing algorithms to complement syndromic diagnostics, improving public health awareness and clinical guidance.</div></div>","PeriodicalId":50767,"journal":{"name":"Annals of Epidemiology","volume":"111 ","pages":"Pages 146-153"},"PeriodicalIF":3.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145259968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annals of EpidemiologyPub Date : 2025-11-01Epub Date: 2025-09-18DOI: 10.1016/j.annepidem.2025.09.012
Sofia Anania MD , Marian K. Bakker PhD , Jorieke E.H. Bergman MD PhD , Leonie K. Duin MD PhD , Mike Ruettermann MD PhD , Dieuwke C. Broekstra PhD
{"title":"Trends in orofacial cleft prevalence and the effect of prenatal detection on pregnancy outcomes in Northern Netherlands","authors":"Sofia Anania MD , Marian K. Bakker PhD , Jorieke E.H. Bergman MD PhD , Leonie K. Duin MD PhD , Mike Ruettermann MD PhD , Dieuwke C. Broekstra PhD","doi":"10.1016/j.annepidem.2025.09.012","DOIUrl":"10.1016/j.annepidem.2025.09.012","url":null,"abstract":"<div><h3>Objectives</h3><div>To describe trends in total and live birth (LB) prevalence of orofacial clefts (OFCs) and investigate the effect of prenatal diagnosis on its LB prevalence in the Northern Netherlands (NNL) over a 21-year period.</div></div><div><h3>Study design</h3><div>Cases with OFCs were selected from Eurocat NNL, a population-based registry of congenital anomalies. Aggregated denominator data (controls) was derived from Statistics Netherlands. We categorized OFCs into cleft lip with or without palate (CL±P) and cleft palate (CP). We analyzed trends in prevalence and temporal patterns in prenatal detection rates and birth type by calculating the annual percentage change (APC) using Joinpoint regression or the <em>X²</em> test for linear trends.</div></div><div><h3>Results</h3><div>The total prevalence of CL±P decreased non-significantly from 1.65/1000 births in 2001 to 1.17/1000 births in 2021 (APC=-0.82 [95 %CI: −2.18, 0.55]), whereas the LB prevalence decreased significantly from 1.57/1000 births in 2001 to 0.93/1000 births in 2021 (APC=-1.65 [95 %CI −3.03, −0.25]). The total and LB prevalence of CP did not show significant decreasing trends.</div><div>The prenatal detection rate of CL±P increased from 15 % to 71 % between 2001 and 2007 (APC=34.38 [95 %CI 24.27, 52.26]), followed by a slower increase, reaching 94 % in 2021 (APC=3.57 [95 %CI 0.59, 6.08]). The percentage of induced abortions increased from 3.2 % to 12.7 % between 2001 and 2021 (<em>X</em><sup><em>2</em></sup> for trend P < 0.001), with most induced abortions occurring in the CL±P associated with genetic/syndromic or other congenital anomalies.</div></div><div><h3>Conclusions</h3><div>The LB prevalence of CL±P decreased, which may be associated with better prenatal detection and increasing pregnancy terminations due to unfavorable prognosis</div></div>","PeriodicalId":50767,"journal":{"name":"Annals of Epidemiology","volume":"111 ","pages":"Pages 44-50"},"PeriodicalIF":3.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145103189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annals of EpidemiologyPub Date : 2025-11-01Epub Date: 2025-09-23DOI: 10.1016/j.annepidem.2025.09.017
Lucas M. Neuroth , Yuni Tang , Anna E. Waller , Katherine J. Harmon
{"title":"Implications of case definition selection on traumatic brain injury trends: A controlled interrupted time-series analysis of North Carolina emergency department data","authors":"Lucas M. Neuroth , Yuni Tang , Anna E. Waller , Katherine J. Harmon","doi":"10.1016/j.annepidem.2025.09.017","DOIUrl":"10.1016/j.annepidem.2025.09.017","url":null,"abstract":"<div><h3>Background</h3><div>In 2015, the CDC removed unspecified head injuries from its TBI surveillance case definition, complicating the investigation of long-term morbidity trends. We examined the long-term impact of this change on quantifying statewide TBI incidence.</div></div><div><h3>Methods</h3><div>North Carolina emergency department (ED) visit records were obtained from 2012 to 2024 and classified based on the presence (S09.90+) or absence (S09.90-) of the ICD-10-CM code for \"head injury, unspecified\". Segmented Poisson regression was used to compare slope- and level-changes in monthly TBI visit counts.</div></div><div><h3>Results</h3><div>From January 2012 through September 2015, TBI visits increased at a rate of 14.9 visits per month. TBI visits dropped at the onset of COVID-19, and then rebounded after the relaxation of the state's stay-at-home-order; however, this trend was diminished under the S09.90- definition, with a difference of 75.9 (57.2–94.6) visits per month between the two definitions.</div></div><div><h3>Conclusions</h3><div>The presence of unspecified head injuries in the TBI surveillance case definition substantially altered statewide trends and their inclusion may better reflect injury burden.</div></div>","PeriodicalId":50767,"journal":{"name":"Annals of Epidemiology","volume":"111 ","pages":"Pages 82-86"},"PeriodicalIF":3.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145151808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annals of EpidemiologyPub Date : 2025-11-01Epub Date: 2025-09-12DOI: 10.1016/j.annepidem.2025.09.008
Glenna Walther , Tilman Brand , Nico Dragano , Claudia Meinke-Franze , Amand Führer , Karin Halina Greiser , Olga Hovardovska , Jamin Kiekert , Lilian Krist , Michael Leitzmann , Wolfgang Lieb , Rafael Mikolajczyk , Ute Mons , Fiona Niedermayer , Nadia Obi , Cara Övermöhle , Marvin Reuter , Börge Schmidt , Ilais Moreno Velásquez , Henry Völzke , Volker Winkler
{"title":"Migration and cardiovascular disease: A comparative study of prevalence and risk factor profiles in resettlers from the German National Cohort (NAKO)","authors":"Glenna Walther , Tilman Brand , Nico Dragano , Claudia Meinke-Franze , Amand Führer , Karin Halina Greiser , Olga Hovardovska , Jamin Kiekert , Lilian Krist , Michael Leitzmann , Wolfgang Lieb , Rafael Mikolajczyk , Ute Mons , Fiona Niedermayer , Nadia Obi , Cara Övermöhle , Marvin Reuter , Börge Schmidt , Ilais Moreno Velásquez , Henry Völzke , Volker Winkler","doi":"10.1016/j.annepidem.2025.09.008","DOIUrl":"10.1016/j.annepidem.2025.09.008","url":null,"abstract":"<div><h3>Aims</h3><div>Resettlers from the former Soviet Union are one of the largest migrant groups in Germany. Previous studies found lower cardiovascular disease (CVD) mortality among resettlers compared to Germans without migration background (autochthonous). Other studies have shown a higher prevalence of CVD risk factors among resettlers, suggesting a higher CVD mortality. The German National Cohort (NAKO) provides an opportunity to explore these discrepancies.</div></div><div><h3>Methods</h3><div>This study used baseline data from NAKO and compared age-adjusted percentages of self-reported CVD and associated risk factors between the two groups. Logistic regression models estimated adjusted odds ratios (OR) for associations between resettler status and outcomes.</div></div><div><h3>Results</h3><div>Among 204,751 participants aged 19–75, 3580 were resettlers and 169,538 autochthonous Germans. Male resettlers had lower odds of risky alcohol consumption (OR: 0.55; 95 %CI: 0.49–0.63) but higher odds of ever smoking (OR: 1.26; 95 %CI: 1.13–1.41) compared to autochthonous German men. Female resettlers showed higher prevalence of hypertension, diabetes mellitus, obesity, and elevated cholesterol/triglycerides, but lower prevalence of risky alcohol consumption and smoking.</div><div>In men, the odds of peripheral artery disease (PAD) (OR: 0.46; 95 %CI: 0.21–0.97) and any CVD (OR: 0.81; 95 %CI: 0.66–0.98) were lower among resettlers. No other notable differences in clinical CVDs were observed in men.</div></div><div><h3>Conclusion</h3><div>Resettlers showed differences regarding CVD risk factor distribution compared to autochthonous Germans. These differences appear to balance out, leading to similar overall CVD prevalence, except for a lower prevalence of PAD and total CVD in male resettlers. Future longitudinal data will allow to explore long-term CVD trajectories.</div></div><div><h3>Lay summary</h3><div>We compared the prevalence of cardiovascular diseases (CVD) in a special group of migrants (resettlers from the former Soviet Union; German: (Spät-)Aussiedler) and autochthonous Germans, using data from the German National Cohort (NAKO) and investigated risk factors frequencies for these diseases in both groups. We found that male resettlers had less of risky alcohol consumption but smoked more than autochthonous German men. Female resettlers showed higher prevalence of hypertension, diabetes mellitus, obesity, and elevated cholesterol and triglyceride levels, but lower prevalence of risky alcohol consumption and smoking. The prevalence of most CVDs was similar in both groups, except of peripheral artery disease and all CVDs combined which we found less frequent in male resettlers.</div></div>","PeriodicalId":50767,"journal":{"name":"Annals of Epidemiology","volume":"111 ","pages":"Pages 14-23"},"PeriodicalIF":3.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145066589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annals of EpidemiologyPub Date : 2025-11-01Epub Date: 2025-09-27DOI: 10.1016/j.annepidem.2025.09.021
Madelin Coyne PhD , Brian Hendricks PhD , Amna Umer PhD , Toni Rudisill PhD , Candice Lefeber MPH , Collin John MD, MPH , Christa Lilly PhD
{"title":"Mapping access to prenatal care: Geographic disparities in West Virginia’s rural communities","authors":"Madelin Coyne PhD , Brian Hendricks PhD , Amna Umer PhD , Toni Rudisill PhD , Candice Lefeber MPH , Collin John MD, MPH , Christa Lilly PhD","doi":"10.1016/j.annepidem.2025.09.021","DOIUrl":"10.1016/j.annepidem.2025.09.021","url":null,"abstract":"<div><h3>Introduction</h3><div>Adequate prenatal care (PNC) is essential to the overall health of mother and her infant. Previous research has demonstrated that rural areas have a higher risk of inadequate PNC compared to their urban counterparts. No studies to date have applied spatial statistical modeling to understand community level factors related to PNC inadequacy.</div></div><div><h3>Purpose</h3><div>To identify communities where the adjusted rate of PNC inadequacy is high, and the insurance type and drive time driving these geographic differences.</div></div><div><h3>Methods</h3><div>Data were obtained from Project WATCH/Birth Score Program for WV zip codes from May 2018 to March 2022. Stratified spatial regression analyses were conducted for women with public and private insurance to understand the extent to which predictors affected risk of PNC inadequacy, and whether relationships differed depending on insurance type.</div></div><div><h3>Results</h3><div>For both insurance types, 30-minute drive time from a birthing facility had a statistically significant association with risk of inadequate PNC (public IRR:3.83, CI:(2.85,5.18)) (private IRR:4.31, CI:(3.17,5.88). Hot spots of model adjusted inadequate PNC risk were clustered in the mid-eastern and southern parts of WV. Importantly, communities with highest risk of inadequate PNC were located further than 30-minutes from a birthing center.</div></div><div><h3>Discussion</h3><div>This study identified strong associations between restricted access to birthing facilities and inadequacy of PNC for women with public and private insurance. Differences in hotspot locations between public and private insurance groups suggest these groups experience different barriers, such as lack of public transportation and drive time.</div></div>","PeriodicalId":50767,"journal":{"name":"Annals of Epidemiology","volume":"111 ","pages":"Pages 88-93"},"PeriodicalIF":3.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145193923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}