Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)最新文献

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THE ANALYSIS STUDY OF MANAGEMENT AND OUTCOMES OF CORNEAL DISEASE: A COMPREHENSIVE SYSTEMATIC REVIEW 角膜病管理和结果的分析研究:全面系统审查
Siswo Utomo, Esa Mahirotul Jamilah
{"title":"THE ANALYSIS STUDY OF MANAGEMENT AND OUTCOMES OF CORNEAL DISEASE: A COMPREHENSIVE SYSTEMATIC REVIEW","authors":"Siswo Utomo, Esa Mahirotul Jamilah","doi":"10.61841/g3bvk356","DOIUrl":"https://doi.org/10.61841/g3bvk356","url":null,"abstract":"Background: A group of conditions affecting the cornea are referred to as corneal disease. These diseases affect over 10 million people worldwide and are caused by various clinical diseases, such as traumatic injuries, chemical burns, infections, and iatrogenic reasons. Causes include bacterial keratitis, fungal keratitis, Herpes Simplex Keratitis (HSK), trachoma, dry eye disease, keratoconus, ophthalmia neonatorum, and non-infectious neonatorum. The causes of corneal disease affect how they are managed. The outcomes of these interventions vary. \u0000The aim: This study aims to determine the management and outcomes of corneal disease. \u0000Methods: By comparing itself to the standards set by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. So, the experts were able to make sure that the study was as up-to-date as it was possible to be. For this search approach, publications that came out between 2014 and 2024 were taken into account. Several different online reference sources, like Pubmed, SAGEPUB, and ScienceDirect, were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done. \u0000Results: In the PubMed database, the results of our search brought up 1358 articles, whereas the results of our search on SAGEPUB brought up 1823 articles, and our search on ScienceDirect brought up 6091 articles. In the end, we compiled 6 papers, 3 of which came from PubMed, 2 of which came from ScienceDirect, and 1 of which came from SagePub. We included six research that met the criteria. \u0000Conclusion: In conclusion, surgical management shows good outcomes in controlling the corneal diseases. It can also maintain structural integrity of cornea and contribute to lowering blindness worldwide.","PeriodicalId":507661,"journal":{"name":"Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)","volume":" 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141374868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE ANALYSIS STUDY OF ONE-STEP COMPARED WITH TWO-STEP GESTATIONAL DIABETES SCREENING AND  PREGNANCY OUTCOMES: A COMPREHENSIVE SYSTEMATIC REVIEW 一步式妊娠糖尿病筛查与两步式妊娠糖尿病筛查及妊娠结局的对比分析研究:全面系统回顾
Vennylia Wijaya
{"title":"THE ANALYSIS STUDY OF ONE-STEP COMPARED WITH TWO-STEP GESTATIONAL DIABETES SCREENING AND  PREGNANCY OUTCOMES: A COMPREHENSIVE SYSTEMATIC REVIEW","authors":"Vennylia Wijaya","doi":"10.61841/339y7254","DOIUrl":"https://doi.org/10.61841/339y7254","url":null,"abstract":"Background: Gestational diabetes mellitus (GDM) is a condition of glucose intolerance developed during pregnancy. Many women with GDM experience pregnancy -related complications, which primarily affect the fetus and include macrosomia, congenital malformations, prematurity, neonatal intensive care unit (NICU) admission, and respiratory distress syndrome. \u0000The aim: The aim of this study to show about the analysis study of one-step compared with two step gestational diabetes screening and pregnancy outcomes. \u0000Methods: By the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. This search approach, publications that came out between 2014 and 2024 were taken into account. Several different online reference sources, like Pubmed, SagePub, and Sciencedirect were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done. \u0000Result: Eight publications were found to be directly related to our ongoing systematic examination after a rigorous three-level screening approach. Subsequently, a comprehensive analysis of the complete text was conducted, and additional scrutiny was given to these articles. \u0000Conclusion: Patients undergoing one- and two-step testing had equal rates of LGA infants, despite a greater likelihood of GDM diagnosis and treatment with one-step testing. Our findings favor two-step testing to minimize the increased burden of GDM diagnosis resulting from one-step testing. However, understanding the long-term implications of such a strategy across the life course is critically important to inform the public health path forward.","PeriodicalId":507661,"journal":{"name":"Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)","volume":"50 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141377395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE ANALYSIS STUDY OF INTERPREGNANCY WEIGHT CHANGE AND HYPERTENSION DURING PREGNANCY: A COMPREHENSIVE SYSTEMATIC REVIEW 妊娠期体重变化与妊娠期高血压的分析研究:一项全面的系统综述
Vennylia Wijaya
{"title":"THE ANALYSIS STUDY OF INTERPREGNANCY WEIGHT CHANGE AND HYPERTENSION DURING PREGNANCY: A COMPREHENSIVE SYSTEMATIC REVIEW","authors":"Vennylia Wijaya","doi":"10.61841/1cn7s592","DOIUrl":"https://doi.org/10.61841/1cn7s592","url":null,"abstract":"Background: The established correlation between high pre-pregnancy body mass index (BMI) and maternal and neonatal complications underscores the urgent need for comprehensive weight management strategies among expectant mother. The aim of this study is to investigate existing evidence on the relationship between interpregnancy weight change and hypertensive disorders during subsequent pregnancies based on literatures of the last 10 years. \u0000Methods: The study adhered to PRISMA 2020 standards, examining English literature from 2014 to 2024. It excluded editorials, reviews from the same journal, and submissions without a DOI. PubMed, SagePub, SpringerLink, and Google Scholar were utilized as literature sources. \u0000Result: Initially retrieving 500 articles from online databases (PubMed, SagePub, SpringerLink and Google Scholar) eight relevant papers were selected after three rounds of screening for full-text analysis. These papers were thoroughly examined to assess the effect of interpregnancy weight change on hypertensive disorders during pregnancy. \u0000Conclusion: Interpregnancy weight gain is linked to a heightened risk of hypertensive disorders during pregnancy. By addressing weight-related factors between pregnancies, healthcare providers can significantly improve maternal health outcomes in subsequent pregnancies.","PeriodicalId":507661,"journal":{"name":"Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)","volume":"28 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141379713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE EFFECT OF HIBISCUS SABDARIFFA LINN.ETHANOLIC EXTRACT ADMINISTRATION ON RAGE, GLP-1 AND GLP-1R EXPRESSIONIN HEART TISSUE OF DIABETIC MICE 木槿乙醇提取物对糖尿病小鼠心脏组织中愤怒、glp-1 和 glp-1r 表达的影响
Lestari YD, Santoso DIS, Goenarjo RA, Paramita N
{"title":"THE EFFECT OF HIBISCUS SABDARIFFA LINN.ETHANOLIC EXTRACT ADMINISTRATION ON RAGE, GLP-1 AND GLP-1R EXPRESSIONIN HEART TISSUE OF DIABETIC MICE","authors":"Lestari YD, Santoso DIS, Goenarjo RA, Paramita N","doi":"10.61841/4r6k0m77","DOIUrl":"https://doi.org/10.61841/4r6k0m77","url":null,"abstract":"Diabetes mellitus (DM) is a multifactorial disease associated with hyperglycemia and an increased risk of complications in the cardiovascular system. During hyperglycemia, there is a significant decrease in GLP-1 and GLP- 1R expression, which have been known to have protective effects on the cardiovascular system. Increased RAGE expression due to hyperglycemia can also lead to inflammation, contributing to the pathogenesis of diabetes complications, specifically cardiovascular diseases. Administration of Hibiscus sabdariffa Linn. (HSL) can improve cardiovascular function, partly by increasing GLP-1 expression and suppressing RAGE expression. The aim of this study is to investigate the effect of HSL administration on RAGE, GLP-1, and GLP-1R expression in the heart. This study is an experimental study using 9-to-11-week-old DDY mice divided into four groups: control (K), DM control (KDM), positive control DM with quercetin (KQ), and DM with HSL at a dose of 400 mg/kgBW (DM-HSL). The experimental animals received treatment for four weeks.The analysis of GLP-1R and RAGE expression was conducted using RT-PCR, while GLP-1 expression were obtained using the ELISA method. The results of this study indicate a decrease in RAGE expression and an increase in GLP-1 and GLP-1R expression in the hearts of diabetic mice. Quercetin administration was also found to decrease RAGE expression, increase GLP-1 expression, and raise GLP- 1R expression in the hearts of diabetic mice. These findings suggest that HSL administration has the potential to protect the cardiovascular system in diabetes, which is related to the activity of GLP-1 and GLP-1R and RAGE.","PeriodicalId":507661,"journal":{"name":"Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)","volume":"3 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141271390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
LAPARASCOPIC VERSUS OPEN MESH REPAIR FOR RECURRENT INGUINAL HERNIA: A SYSTEMATIC REVIEW 腹腔镜与开放式网片修补术治疗复发性腹股沟疝:系统性综述
Kevin Gabriel, Siemon Junior Berhimpon
{"title":"LAPARASCOPIC VERSUS OPEN MESH REPAIR FOR RECURRENT INGUINAL HERNIA: A SYSTEMATIC REVIEW","authors":"Kevin Gabriel, Siemon Junior Berhimpon","doi":"10.61841/7d4qq784","DOIUrl":"https://doi.org/10.61841/7d4qq784","url":null,"abstract":"Background: Inguinal hernia is one of the most common conditions seen in clinic, and is often treated through the general surgery department. Laparoscopic repair and open repair with mesh are the typical treatments for inguinal hernia, and both regimens have proved beneficial in treating inguinal hernia. However, recurrence, with a rate as high as 33, poses a significant problem to the effective treatment of inguinal hernia.\u0000The aim: This study aims to show about laparascopic versus open mesh repair for recurrent inguinal hernia. \u0000Methods: By comparing itself to the standards set by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. So, the experts were able to make sure that the study was as up-to-date as it was possible to be. For this search approach, publications that came out between 2013 and 2023 were taken into account. Several different online reference sources, like Pubmed and SagePub, were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done. \u0000Result: In the PubMed database, the results of our search brought up 10 articles, whereas the results of our search on SagePub brought up 60 articles. The results of the search conducted for the last year of 2013 yielded a total 2 articles for PubMed and 14 articles for SagePub. The result from title screening, a total 1 articles for PubMed and 10 articles for SagePub. In the end, we compiled a total of 7 papers. We included five research that met the criteria. \u0000Conclusion: The laparoscopic approach is superior to the open mesh approach for the repair of recurrent inguinal hernia in some aspects, including the incision infection rate and length of hospital stay. However, more high-quality studies on the effects of laparoscopic and open mesh repair for the treatment of recurrent inguinal hernia are warranted.","PeriodicalId":507661,"journal":{"name":"Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)","volume":"39 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141270057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PREVALENCE, MANAGEMENT, AND OUTCOME OF BELLS PALSY : A COMPREHENSIVE SYSTEMATIC REVIEW 钟性麻痹的患病率、管理和预后:全面系统综述
Mirna Ayu Permata Sari, Cahyanu Mardika
{"title":"PREVALENCE, MANAGEMENT, AND OUTCOME OF BELLS PALSY : A COMPREHENSIVE SYSTEMATIC REVIEW","authors":"Mirna Ayu Permata Sari, Cahyanu Mardika","doi":"10.61841/evztbg31","DOIUrl":"https://doi.org/10.61841/evztbg31","url":null,"abstract":"Background: Bell’s palsy, also called idiopathic facial paralysis, is defined as an acute-onset, isolated, unilateral, lower motor neurone facial weakness. The reported annual incidence varies in different parts of the world with estimates varying between 11 and 40 per 100 000 people. \u0000The aim: The aim of this study to show about prevalence, management, and outcome of bell’s palsy. \u0000Methods: By the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. This search approach, publications that came out between 2014 and 2024 were taken into account. Several different online reference sources, like Pubmed, SagePub, and Sciencedirect were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done. \u0000Result: Eight publications were found to be directly related to our ongoing systematic examination after a rigorous three-level screening approach. Subsequently, a comprehensive analysis of the complete text was conducted, and additional scrutiny was given to these articles. \u0000Conclusion: Bell's palsy is a common but still controversial disease, with unknown etiology until now. Modern literature showed that up to 80 percent of the patients will recover without treatment.","PeriodicalId":507661,"journal":{"name":"Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)","volume":"28 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141270784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE STUDY OF EFFECT PROBIOTIC IN ACNE AND ROSACEA : A SYSTEMATIC REVIEW 研究益生菌对痤疮和酒渣鼻的影响:系统综述
Novitafalen, Nathania Christika, Henyta, Ririn Azhari, Astrid Ananda, Afdila Syarfina
{"title":"THE STUDY OF EFFECT PROBIOTIC IN ACNE AND ROSACEA : A SYSTEMATIC REVIEW","authors":"Novitafalen, Nathania Christika, Henyta, Ririn Azhari, Astrid Ananda, Afdila Syarfina","doi":"10.61841/ftca7b80","DOIUrl":"https://doi.org/10.61841/ftca7b80","url":null,"abstract":"Background: Alternative remedies have long been utilized by patients to treat skin diseases in addition to or instead of traditional medical care. Research on the relationship between probiotics, the skin microbiota, and inflammatory dermatoses is only getting started.\u0000Aims : This systematic review is to review the association of probiotic and its effect in acne and rosacea.\u0000Methods: This study demonstrated compliance with all requirements by means of a comparison with the standards established by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020. Thus, the specialists were able to guarantee that the research was as current as feasible. Publications released between 2014 and 2024 were considered for this search strategy. This was accomplished by utilizing a number of distinct online reference sites, including Pubmed, ScienceDirect, and SagePub. It was determined that reviews, previously published works, and partially completed works would not be included. \u0000Result: In the PubMed database, the results of our search brought up 19 articles, whereas the results of our search on SCIENCE DIRECT brought up 166 articles, our search on SAGEPUB brought up 10 articles. The results of the search conducted for the last year of 2014 yielded a total 18 articles for PubMed, 122 articles for SCIENCE DIRECT and 7 articles for SAGEPUB. In the end, we compiled a total of  6 papers, 3 of which came from PubMed, 2 of which came from SCIENCE DIRECT and 1 of which came from SAGEPUB. We included six research that met the criteria.\u0000Conclusion: In summary, manyof the studies that are currently available in the literature only involved a limited number of patients, did not state which species or dosage of probiotics were utilized, or did not run their trials long enough to fully assess the effects of probiotics on the microbiome of the skin and stomach.","PeriodicalId":507661,"journal":{"name":"Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)","volume":"20 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141110923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
GRAFTS COMPARISON BETWEEN QUADRICEPS TENDON AUTOGRAFT VS. ALLOGRAFT FOR ANTERIOR CRUCIATE LIGAMENT REVISIOON RECONSTRUCTION: A LITERATURE REVIEW 前交叉韧带重建中股四头肌腱自体移植物与异体移植物的比较:文献综述前十字韧带再造的同种异体移植:文献综述
Ariq Muflih Halim Hasibuan, Permana Yudhadibrata
{"title":"GRAFTS COMPARISON BETWEEN QUADRICEPS TENDON AUTOGRAFT VS. ALLOGRAFT FOR ANTERIOR CRUCIATE LIGAMENT REVISIOON RECONSTRUCTION: A LITERATURE REVIEW","authors":"Ariq Muflih Halim Hasibuan, Permana Yudhadibrata","doi":"10.61841/vvaz1b13","DOIUrl":"https://doi.org/10.61841/vvaz1b13","url":null,"abstract":"Introduction: Anterior cruciate ligament (ACL) reconstruction is one of the most common orthopaedic surgeries performed on active people in the world. One of the most important surgical decisions is graft type for use in the reconstruction. Recently, the quadriceps tendon has gained popularity for use as a graft source for ACL reconstruction. The graft choice is broadly between an autograft or allograft. This review aims to understand the current concepts in graft comparison between quadriceps tendon autograft vs. allograft for anterior cruciate ligament revision reconstruction.\u0000Methods: This literature review study was reported following the preferred reporting items for systematic reviews and adhered to a structured review protocol. The author searched the PubMed, ScienceDirect, and British Medical Journal databases. The authors comparing selected publications reporting patient outcomes with all types of reviews or descriptions of ACL revision reconstruction and its graft being used or other related subjects. Published in English is included. The author then formulates a synthesis to support the previously determined research objectives.\u0000Results: ACL reconstruction with partial thickness soft tissue quadriceps tendon graft is a reliable option. Where there are differences in the failure rates of ACL reconstructions between allografts and autografts, these can mostly be explained by irradiated grafts. Giving sufficient radiation to achieve sterility will likely weaken grafts and make them more likely to fail; therefore, irradiating grafts is not recommended. The evidence shows no significant differences in clinical effectiveness between autografts and non-irradiated allografts. Failure rates with both grafts are now low.\u0000Discussion: The primary goals of rehabilitation after ACL reconstruction do not vary considerably based on graft type and emphasize: (1) restoration of the full range of motion, (2) normalization of quadriceps strength, (3) improvement of overall lower extremity muscle strength, and (4) re-training of movement patterns to return to pre-injury sports participation while decreasing injury risk. Achieving full motion and quadriceps strength contributes to a rapid return to normal weight bearing, gait, and activities of daily living. In the setting of revision ACL reconstruction, there are various considerations regarding graft choice due to tunnel size or position, previous usage of other grafts, and reconstructions in the other leg, which may mean that allografts would be preferred to autografts. The other population not covered sufficiently in the literature is the elite sprinting athlete, where autograft choices may be influenced by the effect of graft harvesting on their sport. However, in most cases, allograft ACL reconstruction with non-irradiated grafts is as safe but more expensive than autograft ACL reconstruction, which is preferred as it is more cost-effective.\u0000Conclusion: There is little difference in the results of ACL","PeriodicalId":507661,"journal":{"name":"Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)","volume":"35 50","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141117454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ASSOCIATION OF ACID REFLUX AND LARYNGOMALACIA : A COMPREHENSIVE SYSTEMATIC REVIEW 胃酸倒流与喉水肿的关系:一项全面的系统综述
Maynanda Primadhiya Sentani, Ramadhani Ferrial Nugraha
{"title":"ASSOCIATION OF ACID REFLUX AND LARYNGOMALACIA : A COMPREHENSIVE SYSTEMATIC REVIEW","authors":"Maynanda Primadhiya Sentani, Ramadhani Ferrial Nugraha","doi":"10.61841/22xk6m60","DOIUrl":"https://doi.org/10.61841/22xk6m60","url":null,"abstract":"Background: Laryngomalacia (LM) is a common cause of stridor in infants and young children. It is characterized by reflux episodes that are slightly acidic, which harm the supraglottic tissues and exacerbate airway collapse. Further investigation is required to ascertain the presence of the gastric proteolytic enzyme pepsin in the oral secretions of patients with less severe LM, as it has been proposed as a biomarker for both weakly acidic and nonacid reflux events. \u0000Methods: This systematic review focused on full-text English literature published between 2014 and 2024, adhering to PRISMA 2020 principles. Without a DOI, editorials and review papers that were published in the same journal as the submission were not accepted. ScienceDirect, PubMed, and SagePub were only a few of the web resources used to compile the literature. \u0000Result: Following a thorough screening process consisting of three stages, six papers were determined to have pertinent connections to our ongoing comprehensive investigation. Following that, the text as a whole was thoroughly studied and these sections received more attention. \u0000Conclusion: Recent research has revealed a link between laryngomalacia (LM) and pepsin, a diagnostic marker, but no significant differences have been found. Pepsin is a common comorbidity in LM patients and serves as a biomarker for airway reflux, but its harmful impact on proximal airways remains unclear.","PeriodicalId":507661,"journal":{"name":"Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)","volume":"4 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141119718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE STUDY OF PREVALENCE, MANAGEMENT AND OUTCOME OF MUSCULOSKELETAL INJURIES IN RUNNERS: A COMPREHENSIVE SYSTEMATIC REVIEW 研究跑步者肌肉骨骼损伤的发生率、管理和结果:全面系统审查
Afdhal Yuli Firlando, Assyifa
{"title":"THE STUDY OF PREVALENCE, MANAGEMENT AND OUTCOME OF MUSCULOSKELETAL INJURIES IN RUNNERS: A COMPREHENSIVE SYSTEMATIC REVIEW","authors":"Afdhal Yuli Firlando, Assyifa","doi":"10.61841/8q6w1y87","DOIUrl":"https://doi.org/10.61841/8q6w1y87","url":null,"abstract":"Background: Running's popularity has surged globally, doubling in the last decade, due to its accessibility and health benefits. However, it carries a high injury risk, especially in lower extremities, with rates varying by distance. Understanding injury prevalence and risk factors is essential. This study aims to serve a comprehensive systematic review to analyze the prevalence, management and outcome of musculoskeletal injuries in runners based on literatures of the last 10 years. \u0000Methods: The review adhered to PRISMA 2020 standards and analyzed full-text English literature from 2014 to 2024. It excluded editorials, review papers from the same journal, and submissions lacking a DOI. Literature sources included PubMed, SagePub, SpringerLink, and Google Scholar. \u0000Result: A total of 655 articles were retrieved from online databases (PubMed, SagePub, SpringerLink and Google Scholar). After three rounds of screening, ten articles directly relevant to the systematic review were selected for full-text reading and analysis. \u0000Conclusion: Musculoskeletal injuries in runners are common. Tailored interventions like gait retraining and targeted exercises can reduce their incidence and severity. Further research is needed to assess long-term effects and develop standardized prevention and management protocols for diverse running populations.","PeriodicalId":507661,"journal":{"name":"Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)","volume":"107 21","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141125699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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