Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)最新文献

{"title":"IMPACT OF TREATMENT OF DIABETIC MACULAR EDEMA ON VISUAL IMPAIRMENT IN PEOPLE WITH TYPE 2 DIABETES MELLITUS: A COMPREHENSIVE SYSTEMATIC REVIEW AND METAAANALYSIST STUDY","authors":"Yovita, Bambang Setiohadji","doi":"10.61841/ja4d6761","DOIUrl":"https://doi.org/10.61841/ja4d6761","url":null,"abstract":"Background: Diabetic retinopathy (DR) and diabetic macular edema (DME) are among the most significant and disabling chronic complications of diabetes mellitus. DME is an important cause of severe vision loss in type 2 diabetes. Hyperpermeability of retinal blood vessels and subsequent formation of edema and hard exudates are the key clinical features. \u0000Method: This systematic review and meta-analysis, conducted following PRISMA guidelines and employing the PICO format, aim to explore about impact of treatment of diabetic macular edema on visual impairment in people with type 2 diabetes mellitus, focusing on treatment, complications, and prognosis. Inclusion criteria encompass diverse study designs (RCTs, observational, quasi-experimental, and case-control studies) investigating impact of treatment of diabetic macular edema on visual impairment in people with type 2 diabetes mellitus among treatment, complications, and prognosis, while exclusion criteria filter out studies lacking relevance to impact of treatment of diabetic macular edema on visual impairment in people with type 2 diabetes mellitus. \u0000Result: After conducting three levels of screening, the results of our search in Pubmed get 6 articles, whereas the results of our search on SageJournal get 42 articles, on Lancet 21, and on Scient direct get 60 articles. Records remove before screening are 91, so we get 78 articles for screening. After we screened based on record exclude, we compiled a total of 10 papers. We included four research that met the criteria.  \u0000Conclusion: There is a particularly robust response to anti-VEGF therapy in both groups when glycemic control is optimized, highlighting the critical importance of communication between the physicians managing the DME and those managing systemic diabetes control. Improving our understanding of the factors that contribute to anti-VEGF response for DME therapy may help to enhance DME treatment outcomes, particularly through the concerted coordinated efforts of the treating retina specialist and the endocrinologist or primary care physician.","PeriodicalId":507661,"journal":{"name":"Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)","volume":"4 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140963075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ASSOCIATION ORAL CORTICOSTEROIDS AND LONG-TERM RISK OF CATARACT: A SYSTEMATIC REVIEW AND META-ANALYSIS STUDY","authors":"Yovita, Bambang Setiohadji","doi":"10.61841/tpn62p53","DOIUrl":"https://doi.org/10.61841/tpn62p53","url":null,"abstract":"Background: Cataracts are a significant health concern, particularly in aging populations, impacting vision, mental well-being, and overall quality of life. Corticosteroid use has been linked to cataract development. This study aims to explore the relationship between oral corticosteroid (OCS) exposure and the long-term risk of cataract. \u0000Method: Following PRISMA guidelines, a systematic review and meta-analysis were conducted to investigate this association. Relevant studies were identified through comprehensive searches across multiple databases. Data included cataract incidence/prevalence and OCS therapy. \u0000Results: A total of 1,270 articles were retrieved from online databases (PubMed, SagePub, SpringerLink and Google Scholar). After three rounds of screening, five articles directly relevant to the systematic review were selected for full-text reading and analysis. These five studies collectively involved 27,250 cases of cataract following oral corticosteroid (OCS) exposure, while 47,267 controls did not develop cataracts. No statistically significant association is found between OCS and cataract formation (OR 0.117, CI 95 0.0085 to 1.6021, p0.11). \u0000Conclusion: Cataracts in oral corticosteroid (OCS) users result from abnormal lens cell movement and protein composition changes due to protein adduct formation. Increased OCS dosage and frequency correlate with higher cataract risk. However, evidence quality was deemed low to moderate, highlighting the need for well-designed RCTs to minimize bias and heterogeneity.","PeriodicalId":507661,"journal":{"name":"Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)","volume":"48 28","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140965724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PREVALENCE AND MANAGEMENT OF IRON DEFICIENCY ANEMIA IN CHILDREN: A SYSTEMATIC REVIEW","authors":"Raden Panji Joy Poespo Koesoemo Aji, Kitty Fabiola, Raden Panji Andreuy Poespo Koesoemoadi, Suhartatik","doi":"10.61841/5yemsy46","DOIUrl":"https://doi.org/10.61841/5yemsy46","url":null,"abstract":"Background: Even in affluent nations, IDA is still a significant public health issue, particularly for young children and women who are ready to have children.\u0000Aims: This systematic review is to review the treatment and prevalence of iron deficiency anemia in children.\u0000Methods: This study demonstrated compliance with all requirements by means of a comparison with the standards established by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020. Thus, the specialists were able to guarantee that the research was as current as feasible. Publications released between 2014 and 2024 were considered for this search strategy. This was accomplished by utilizing a number of distinct online reference sites, including Pubmed, ScienceDirect, and SagePub. It was determined that reviews, previously published works, and partially completed works would not be included. \u0000Result: In the PubMed database, the results of our search brought up 353 articles, whereas the results of our search on SCIENCE DIRECT brought up 8.865 articles, our search on SAGEPUB brought up 3.269 articles. The results of the search conducted for the last year of 2014 yielded a total 184 articles for PubMed, 4.071 articles for SCIENCE DIRECT and 1.144 articles for SAGEPUB. In the end, we compiled a total of 5 papers, 3 of which came from PubMed, 1 of which came from SCIENCE DIRECT and 1 of which came from SAGEPUB. We included five research that met the criteria.\u0000Conclusion: In summary, with its haematological repercussions of anemia, IDA is a prevalent and significant children health concern. To assess the effects of IDA on immunity and neurocognition, additional research is necessary. The key to successfully treating children with IDA is early identification and diagnosis of the condition together with competent interpretation of laboratory tests.","PeriodicalId":507661,"journal":{"name":"Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)","volume":"46 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140970478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"FACTOR ASSOCIATED OF CHRONIC KIDNEY DISEASE OF UNCERTAIN ETIOLOGY: A COMPREHENSIVE SYSTEMATIC REVIEW","authors":"Andreas Natan, Alvin Alkhaliq","doi":"10.61841/93d71f10","DOIUrl":"https://doi.org/10.61841/93d71f10","url":null,"abstract":"Background: Recent interest in chronic kidney disease of non-traditional causes, also named as chronic kidney disease of unknown etiology (CKDu) has identified both individual and environmental/occupational risk factors. \u0000The aim: The aim of this study to show factor associated of chronic kidney disease of uncertain etiology. \u0000Methods: By the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. This search approach, publications that came out between 2014 and 2024 were taken into account. Several different online reference sources, like Pubmed, SagePub, and Sciencedirect were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done. \u0000Result: the results of our search get 91 articles, whereas the results of our search on SagePub get 1976 articles, on Sciencedirect 14.279 articles. Records remove before screening are 5676, so we get 10670 articles fos screening. We included five research that met the criteria. \u0000Conclusion: Different multifactorial etiologies like chronic exposure to dehydration, heat stress, agrochemicals, heavy metals, intake of fructose-rich drinks, frequent use of self-prescribed non- steroidal anti-inflammatory drugs (NSAIDS), lower income and genetics were proposed in its development.","PeriodicalId":507661,"journal":{"name":"Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)","volume":"9 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140967057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE STUDY OF RISK FACTOR AND STRATEGIES FOR PREVENTION OF RECURRENT ISCHEMIC STROKE :A COMPREHENSIVE SYSTEMATIC REVIEW","authors":"Ibnu Ibni Rizal, Ghiffany Octaviantie","doi":"10.61841/w0n2j027","DOIUrl":"https://doi.org/10.61841/w0n2j027","url":null,"abstract":"Background: Studies show that the majority of strokes are caused by modifiable risk factors, such as high-fat diets, sleep apnea, diabetes, heart disorders, and other diseases. Recurrence rates are higher in sub-Saharan Africa (SSA), where strokes occur in the fourth or fifth decades of life. To reduce the risk of stroke recurrence and death, individuals who have survived their first stroke must undergo regular medical follow-up. Understanding the risk factors for stroke recurrence can help create plans and treatments to lessen the burden of strokes. Regular medical follow-up and understanding these risk factors can help create effective treatments and plans to reduce stroke recurrence. \u0000Methods: This systematic review focused on full-text English literature published between 2014 and 2024, adhering to PRISMA 2020 principles. Without a DOI, editorials and review papers that were published in the same journal as the submission were not accepted. ScienceDirect, PubMed, and SagePub were among the many web resources used to compile the literature. \u0000Result: Using reliable resources including Science Direct, SagePub, and PubMed, the study examined over 7,000 publications. Following the determination that seven publications warranted a further inquiry, a more thorough examination of the full corpus was conducted. \u0000Conclusion: Risk factors such as hypertension, alcohol consumption, diabetes, female gender, non-adherence to treatment, and cardiac causes contribute to high stroke recurrence rates in sub-Saharan Africa. Treatment effectiveness varies among ethnic groups, with DAPT being effective in patients with ICAD. Statin-based therapies reduce recurrent stroke risk but increase hemorrhagic stroke risk. Vitamin D plays a crucial role in brain development.","PeriodicalId":507661,"journal":{"name":"Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)","volume":"2 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140982225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COMPARISON BETWEEN NEBULISATION OF MGSO4 20 MG/KGBW WITH KETAMINE 0.5 MG/KGBW ON THE INCIDENT OF POST-OPERATIVE SORE THROAT DUE TO ENDOTRACHEAL INTUBATION IN PATIENTS UNDERGOING GENERAL ANESTHESIA IN DR. HASAN SADIKIN HOSPITALS BANDUNG","authors":"Reza Widianto Sudjud, Muchammad Erias Erlangga, Diki Akbar","doi":"10.61841/7hyssr73","DOIUrl":"https://doi.org/10.61841/7hyssr73","url":null,"abstract":"Post Operative Sore Throat (POST) is a Symptoms often experienced by patients after surgery under general anesthesia and endotracheal intubation. The incidence of POST is between 21-71.8. POST causes discomfort to patients which can prolong hospital stay. In this study, a comparison was made between MgSO4 nebulization 20 mg/ KgBW and ketamine nebulization 0.5 mg/ KgBW on the incidence of POST after general anesthesia at RSUP Dr. Hasan Sadikin Bandung . This study used a double blind randomized controlled trial design. 72 elective surgery patients were randomly divided into 2 groups. Group M was given MgSO4 nebulization while group K was given ketamine nebulization. Nebulization was performed 15 minutes before induction of general anesthesia. POST monitoring was performed at 1, 4 and 24 hours after extubation using POST scoring. In this study, it was found that the incidence of POST in group M, namely the 1st hour of 13.5, the 4th hour of 10.8 and the 24th hour of 0 was lower than that in group K, namely the 1st hour of 28.5, the 4th hour of 32.5 and the 24th hour of 0. Statistical test results p0.033 showed a significant difference in group M better than group K at the 4th hour in reducing the incidence of POST. MgSO4 and ketamine have antinociceptive and anti-inflammatory effects with the mechanism of action of blocking NMDA receptors that inhibit calcium influx that avoids central sensitization. MgSO4 also has a muscle relaxing effect and reduces airway mucus secretion, thus reducing the risk of trauma during endotracheal intubation. The conclusion of this study is that MgSO4 nebulization shows a lower incidence of POST than ketamine nebulization.","PeriodicalId":507661,"journal":{"name":"Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)","volume":"102 14","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140986061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ASSOCIATION OF BETA BLOCKER USE AND COPD MORTALITY: A SYSTEMATIC REVIEW","authors":"Dwi Wahyu Setyo Irawan, Hermawan Chrisdiono","doi":"10.61841/vfr8c875","DOIUrl":"https://doi.org/10.61841/vfr8c875","url":null,"abstract":"Background: Chronic obstructive pulmonary disease (COPD) it is currently the third greatest cause of mortality worldwide and one of the main causes of morbidity\u0000Aims: This systematic review is to review the association of beta blocker use and COPD mortality.\u0000Methods: This study demonstrated compliance with all requirements by means of a comparison with the standards established by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020. Thus, the specialists were able to guarantee that the research was as current as feasible. Publications released between 2014 and 2024 were considered for this search strategy. This was accomplished by utilizing a number of distinct online reference sites, including Pubmed, ScienceDirect, and SagePub. It was determined that reviews, previously published works, and partially completed works would not be included. \u0000Result: In the PubMed database, the results of our search brought up 249 articles, whereas the results of our search on SCIENCE DIRECT brought up 18.876 articles, our search on SAGEPUB brought up 4.844 articles. The results of the search conducted for the last year of 2014 yielded a total 131 articles for PubMed, 6.875 articles for SCIENCE DIRECT and 1.840 articles for SAGEPUB. In the end, we compiled a total of 8 papers, 5 of which came from PubMed, 2 of which came from SCIENCE DIRECT and 1 of which came from SAGEPUB. We included eight research that met the criteria.\u0000Conclusion: In summary, beta blockers showed the effect to reduce the exacerbation or exacerbation related mortality of COPD in some cases. More studies needed in the future for more evidence of the use of beta blockers as the treatments in patients with COPD.","PeriodicalId":507661,"journal":{"name":"Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)","volume":"62 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140983528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE STUDY OF COMPARISON OF SINGLE-INCISION  LAPAROSCOPIC VERSUS CONVENTIONAL LAPAROSCOPIC APPENDECTOMY: A COMPREHENSIVE SYSTEMATIC REVIEW","authors":"Fredy Satrio Nugroho, Rudolf Rudy Budiantoro, Wahyu Nur Alamsyah","doi":"10.61841/wrfaxr48","DOIUrl":"https://doi.org/10.61841/wrfaxr48","url":null,"abstract":"Background: Acute appendicitis is highly prevalent in children with an acute abdomen, and appendectomy is still the main method of treatment for this disease. The standard treatments for acute appendicitis are early open surgery and laparoscopic surgery. \u0000The aim: The aim of this study to show about comparison of single incision laparoscopic versus conventional laparoscopic appendectomy. \u0000Methods: By the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. This search approach, publications that came out between 2014 and 2024 were taken into account. Several different online reference sources, like Pubmed, SagePub, and Sciencedirect were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done. \u0000Result: Eight publications were found to be directly related to our ongoing systematic examination after a rigorous three-level screening approach. Subsequently, a comprehensive analysis of the complete text was conducted, and additional scrutiny was given to these articles. \u0000Conclusion: HLA has a negative impact on quality of life and aesthetics because it requires three surgical incisions. On the contrary, in single-incision transumbilical laparoscopic appendicectomy (SILA), the incision is made around the umbilicus.","PeriodicalId":507661,"journal":{"name":"Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)","volume":" 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140988755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"POST-OPERATIVE PROTOCOL FOR BRAIN TUMOR SURGERY IN INTENSIVE CARE UNIT: A LITERATURE REVIEW","authors":"Dwi Indriati Kusumawardani, Bowo Adiyanto","doi":"10.61841/vv043b66","DOIUrl":"https://doi.org/10.61841/vv043b66","url":null,"abstract":"Background: Brain tumors represent a diverse group of neoplasms arising from intracranial tissues, posing significant clinical challenges and impacting public health globally. With primary brain tumors having an annual incidence of around 14 per 100,000 individuals and secondary brain tumors being even more prevalent, the burden on healthcare systems is substantial. Postoperative care, particularly in the intensive care unit (ICU), plays a crucial role in monitoring patients for early detection of complications and maintaining neurological and systemic homeostasis.  This study aims to serve a literature review to examine post operative management in brain surgery operation in the ICU in literatures.  \u0000Result and Discussion: Protocols for ICU management post-brain tumor surgery are essential, with factors such as patient status, surgical site, and anticipated postoperative needs guiding decisions regarding ICU admission and monitoring. Neuroprotective strategies encompass physiological and pharmacological interventions aimed at mitigating adverse outcomes, with a multifaceted approach necessary for optimal neuroprotection. \u0000Conclusion: A comprehensive understanding of the surgical and postoperative management of brain tumors along with the implementation of evidence-based protocols for ICU care are essential to improve patient outcomes and minimize complications. Continued advancements in surgical techniques, neuroprotective strategies, and critical care management are crucial in addressing the complex challenges posed by brain tumors and enhancing the quality of care for affected patients.","PeriodicalId":507661,"journal":{"name":"Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)","volume":" 30","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140993397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SCREENING AND EARLY DETECTION OF LUNG CANCER: A COMPREHENSIVE SYSTEMATIC REVIEW","authors":"Nurhidayati Agustin Arifah Y, Fadhiel Yudistiro","doi":"10.61841/3prhn126","DOIUrl":"https://doi.org/10.61841/3prhn126","url":null,"abstract":"Background: Lung cancer is the second most commonly diagnosed cancer and the leading cause of cancer-related deaths globally, accounting for the greatest economic and public health burden of all cancers. In 2020, lung cancer accounted for approximately 2.2 million cases and nearly 1.8 million deaths worldwide. \u0000The aim: The aim of this study to show about screening and early detection of lung cancer. \u0000Methods: By the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. This search approach, publications that came out between 2014 and 2024 were taken into account. Several different online reference sources, like Pubmed, SagePub, and Sciencedirect were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done. \u0000Result: Four publications were found to be directly related to our ongoing systematic examination after a rigorous three-level screening approach. Subsequently, a comprehensive analysis of the complete text was conducted, and additional scrutiny was given to these articles. \u0000Conclusion: Early screening and diagnostic methods of lung cancer, x-ray screening is not recommended. LDCT has obvious advantages and is the most promising imaging method in early screening of lung cancer.","PeriodicalId":507661,"journal":{"name":"Journal of Advanced Research in Medical and Health Science (ISSN 2208-2425)","volume":" 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140996704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}