前交叉韧带重建中股四头肌腱自体移植物与异体移植物的比较:文献综述前十字韧带再造的同种异体移植:文献综述

Ariq Muflih Halim Hasibuan, Permana Yudhadibrata
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The author searched the PubMed, ScienceDirect, and British Medical Journal databases. The authors comparing selected publications reporting patient outcomes with all types of reviews or descriptions of ACL revision reconstruction and its graft being used or other related subjects. Published in English is included. The author then formulates a synthesis to support the previously determined research objectives.\nResults: ACL reconstruction with partial thickness soft tissue quadriceps tendon graft is a reliable option. Where there are differences in the failure rates of ACL reconstructions between allografts and autografts, these can mostly be explained by irradiated grafts. Giving sufficient radiation to achieve sterility will likely weaken grafts and make them more likely to fail; therefore, irradiating grafts is not recommended. The evidence shows no significant differences in clinical effectiveness between autografts and non-irradiated allografts. 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引用次数: 0

摘要

简介前交叉韧带(ACL)重建是世界上最常见的骨科手术之一。最重要的手术决定之一是重建中使用的移植物类型。最近,股四头肌腱作为前交叉韧带重建的移植物来源越来越受欢迎。移植物的选择大致分为自体移植物和异体移植物。本综述旨在了解目前在前交叉韧带翻修重建中,股四头肌腱自体移植物与异体移植物之间的移植物比较概念:本文献综述研究按照系统综述的首选报告项目进行报告,并遵守结构化综述协议。作者检索了 PubMed、ScienceDirect 和《英国医学杂志》数据库。作者比较了所选的报告患者预后的出版物,以及有关前交叉韧带翻修重建及其所用移植物或其他相关主题的所有类型的综述或描述。包括以英语发表的文章。然后,作者进行综合分析,以支持之前确定的研究目标:结果:使用部分厚度的软组织股四头肌腱移植进行前交叉韧带重建是一种可靠的选择。在前交叉韧带重建的失败率方面,同种移植物和自体移植物之间存在差异,这主要是由于移植物经过辐照造成的。为达到无菌状态而进行充分的辐射可能会削弱移植物的强度,使其更容易失败;因此,不建议对移植物进行辐射。有证据显示,自体移植物与未经过辐照的异体移植物在临床效果上没有明显差异。目前,两种移植物的失败率都很低:讨论:前交叉韧带重建术后康复的主要目标并不因移植物类型的不同而有很大差异,主要强调:(1) 恢复全部活动范围;(2) 股四头肌力量恢复正常;(3) 改善整体下肢肌肉力量;(4) 重新训练运动模式,以恢复受伤前的运动参与,同时降低受伤风险。实现完全运动和股四头肌力量有助于快速恢复正常负重、步态和日常生活活动。在前交叉韧带翻修重建中,由于隧道大小或位置、以前使用过其他移植物以及在另一条腿上进行过重建等原因,移植物的选择有多种考虑因素,这可能意味着异体移植物比自体移植物更受青睐。文献中未充分涉及的另一种人群是精英短跑运动员,他们在选择自体移植物时可能会受到移植物采集对其运动的影响。不过,在大多数情况下,使用非辐照移植物进行同种异体前交叉韧带重建与自体移植物前交叉韧带重建相比同样安全,但成本更高,因为自体移植物前交叉韧带重建更具成本效益:结论:使用自体移植物或未经辐照的异体移植物进行前交叉韧带重建的效果差别不大,自体移植物更具优势。异体移植物的成本较高。因此,如果可以使用自体移植物,异体移植物就不具成本效益。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
GRAFTS COMPARISON BETWEEN QUADRICEPS TENDON AUTOGRAFT VS. ALLOGRAFT FOR ANTERIOR CRUCIATE LIGAMENT REVISIOON RECONSTRUCTION: A LITERATURE REVIEW
Introduction: Anterior cruciate ligament (ACL) reconstruction is one of the most common orthopaedic surgeries performed on active people in the world. One of the most important surgical decisions is graft type for use in the reconstruction. Recently, the quadriceps tendon has gained popularity for use as a graft source for ACL reconstruction. The graft choice is broadly between an autograft or allograft. This review aims to understand the current concepts in graft comparison between quadriceps tendon autograft vs. allograft for anterior cruciate ligament revision reconstruction. Methods: This literature review study was reported following the preferred reporting items for systematic reviews and adhered to a structured review protocol. The author searched the PubMed, ScienceDirect, and British Medical Journal databases. The authors comparing selected publications reporting patient outcomes with all types of reviews or descriptions of ACL revision reconstruction and its graft being used or other related subjects. Published in English is included. The author then formulates a synthesis to support the previously determined research objectives. Results: ACL reconstruction with partial thickness soft tissue quadriceps tendon graft is a reliable option. Where there are differences in the failure rates of ACL reconstructions between allografts and autografts, these can mostly be explained by irradiated grafts. Giving sufficient radiation to achieve sterility will likely weaken grafts and make them more likely to fail; therefore, irradiating grafts is not recommended. The evidence shows no significant differences in clinical effectiveness between autografts and non-irradiated allografts. Failure rates with both grafts are now low. Discussion: The primary goals of rehabilitation after ACL reconstruction do not vary considerably based on graft type and emphasize: (1) restoration of the full range of motion, (2) normalization of quadriceps strength, (3) improvement of overall lower extremity muscle strength, and (4) re-training of movement patterns to return to pre-injury sports participation while decreasing injury risk. Achieving full motion and quadriceps strength contributes to a rapid return to normal weight bearing, gait, and activities of daily living. In the setting of revision ACL reconstruction, there are various considerations regarding graft choice due to tunnel size or position, previous usage of other grafts, and reconstructions in the other leg, which may mean that allografts would be preferred to autografts. The other population not covered sufficiently in the literature is the elite sprinting athlete, where autograft choices may be influenced by the effect of graft harvesting on their sport. However, in most cases, allograft ACL reconstruction with non-irradiated grafts is as safe but more expensive than autograft ACL reconstruction, which is preferred as it is more cost-effective. Conclusion: There is little difference in the results of ACL reconstruction with autografts or non-irradiated allografts, with any advantage being with autografts. The cost is higher with allografts. So if autografts are available, allografts are not cost-effective.
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