Annual Review of Biomedical Engineering最新文献_第7页

Mechanical Control of Cell Differentiation: Insights from the Early Embryo. 细胞分化的机械控制:来自早期胚胎的见解。

IF 9.7 1区工程技术

Annual Review of Biomedical Engineering Pub Date : 2022-04-06 DOI: 10.1146/annurev-bioeng-060418-052527

C. Nelson

引用次数: 5

Derivation and Differentiation of Human Pluripotent Stem Cells in Microfluidic Devices. 人多能干细胞在微流控装置中的衍生与分化。

IF 9.7 1区工程技术

Annual Review of Biomedical Engineering Pub Date : 2022-04-04 DOI: 10.1146/annurev-bioeng-092021-042744

C. Luni, O. Gagliano, N. Elvassore

{"title":"Derivation and Differentiation of Human Pluripotent Stem Cells in Microfluidic Devices.","authors":"C. Luni, O. Gagliano, N. Elvassore","doi":"10.1146/annurev-bioeng-092021-042744","DOIUrl":"https://doi.org/10.1146/annurev-bioeng-092021-042744","url":null,"abstract":"An integrative approach based on microfluidic design and stem cell biology enables capture of the spatial-temporal environmental evolution underpinning epigenetic remodeling and the morphogenetic process. We examine the body of literature that encompasses microfluidic applications where human induced pluripotent stem cells are derived starting from human somatic cells and where human pluripotent stem cells are differentiated into different cell types. We focus on recent studies where the intrinsic features of microfluidics have been exploited to control the reprogramming and differentiation trajectory at the microscale, including the capability of manipulating the fluid velocity field, mass transport regime, and controllable composition within micro- to nanoliter volumes in space and time. We also discuss studies of emerging microfluidic technologies and applications. Finally, we critically discuss perspectives and challenges in the field and how these could be instrumental for bringing about significant biological advances in the field of stem cell engineering. Expected final online publication date for the Annual Review of Biomedical Engineering, Volume 24 is June 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.","PeriodicalId":50757,"journal":{"name":"Annual Review of Biomedical Engineering","volume":" ","pages":""},"PeriodicalIF":9.7,"publicationDate":"2022-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46237375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Cuffless Blood Pressure Measurement. 无袖带血压测量。

IF 9.7 1区工程技术

Annual Review of Biomedical Engineering Pub Date : 2022-04-01 DOI: 10.1146/annurev-bioeng-110220-014644

R. Mukkamala, G. Stergiou, A. Avolio

{"title":"Cuffless Blood Pressure Measurement.","authors":"R. Mukkamala, G. Stergiou, A. Avolio","doi":"10.1146/annurev-bioeng-110220-014644","DOIUrl":"https://doi.org/10.1146/annurev-bioeng-110220-014644","url":null,"abstract":"Cuffless blood pressure (BP) measurement has become a popular field due to clinical need and technological opportunity. However, no method has been broadly accepted hitherto. The objective of this review is to accelerate progress in the development and application of cuffless BP measurement methods. We begin by describing the principles of conventional BP measurement, outstanding hypertension/hypotension problems that could be addressed with cuffless methods, and recent technological advances, including smartphone proliferation and wearable sensing, that are driving the field. We then present all major cuffless methods under investigation, including their current evidence. Our presentation includes calibrated methods (i.e., pulse transit time, pulse wave analysis, and facial video processing) and uncalibrated methods (i.e., cuffless oscillometry, ultrasound, and volume control). The calibrated methods can offer convenience advantages, whereas the uncalibrated methods do not require periodic cuff device usage or demographic inputs. We conclude by summarizing the field and highlighting potentially useful future research directions. Expected final online publication date for the Annual Review of Biomedical Engineering, Volume 24 is June 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.","PeriodicalId":50757,"journal":{"name":"Annual Review of Biomedical Engineering","volume":" ","pages":""},"PeriodicalIF":9.7,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43701137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 28

Regenerative Approaches for Chronic Wounds. 慢性伤口的再生方法。

IF 9.7 1区工程技术

Annual Review of Biomedical Engineering Pub Date : 2022-02-28 DOI: 10.1146/annurev-bioeng-010220-113008

F. Berthiaume, H. Hsia

{"title":"Regenerative Approaches for Chronic Wounds.","authors":"F. Berthiaume, H. Hsia","doi":"10.1146/annurev-bioeng-010220-113008","DOIUrl":"https://doi.org/10.1146/annurev-bioeng-010220-113008","url":null,"abstract":"Chronic skin wounds are commonly found in older individuals who have impaired circulation due to diabetes or are immobilized due to physical disability. Chronic wounds pose a severe burden to the health-care system and are likely to become increasingly prevalent in aging populations. Various treatment approaches exist to help the healing process, although the healed tissue does not generally recapitulate intact skin but rather forms a scar that has inferior mechanical properties and that lacks appendages such as hair or sweat glands. This article describes new experimental avenues for attempting to improve the regenerative response of skin using biophysical techniques as well as biochemical methods, in some cases by trying to harness the potential of stem cells, either endogenous to the host or provided exogenously, to regenerate the skin. These approaches primarily address the local wound environment and should likely be combined with other modalities to address regional and systemic disease, as well as social determinants of health. Expected final online publication date for the Annual Review of Biomedical Engineering, Volume 24 is June 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.","PeriodicalId":50757,"journal":{"name":"Annual Review of Biomedical Engineering","volume":"1 1","pages":""},"PeriodicalIF":9.7,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42540923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Integrating Biomaterials and Genome Editing Approaches to Advance Biomedical Science. 整合生物材料和基因组编辑方法，推动生物医学科学的发展。

IF 12.8 1区工程技术

Annual Review of Biomedical Engineering Pub Date : 2021-07-13 Epub Date: 2021-04-28 DOI: 10.1146/annurev-bioeng-122019-121602

Amr A Abdeen, Brian D Cosgrove, Charles A Gersbach, Krishanu Saha

引用次数: 0

Red Blood Cell Hitchhiking: A Novel Approach for Vascular Delivery of Nanocarriers. 红细胞搭便车：纳米载体血管输送的新方法

IF 9.7 1区工程技术

Annual Review of Biomedical Engineering Pub Date : 2021-07-13 Epub Date: 2021-03-31 DOI: 10.1146/annurev-bioeng-121219-024239

Jacob S Brenner, Samir Mitragotri, Vladimir R Muzykantov

引用次数: 0

Therapeutic Agent Delivery Across the Blood-Brain Barrier Using Focused Ultrasound. 聚焦超声在血脑屏障传递治疗药物中的应用。

IF 9.7 1区工程技术

Annual Review of Biomedical Engineering Pub Date : 2021-07-13 DOI: 10.1146/annurev-bioeng-062117-121238

Dallan McMahon, Meaghan A O'Reilly, Kullervo Hynynen

引用次数: 30

Signaling, Deconstructed: Using Optogenetics to Dissect and Direct Information Flow in Biological Systems. 信号，解构:利用光遗传学来解剖和指导生物系统中的信息流。

IF 9.7 1区工程技术

Annual Review of Biomedical Engineering Pub Date : 2021-07-13 DOI: 10.1146/annurev-bioeng-083120-111648

Payam E Farahani, Ellen H Reed, Evan J Underhill, Kazuhiro Aoki, Jared E Toettcher

{"title":"Signaling, Deconstructed: Using Optogenetics to Dissect and Direct Information Flow in Biological Systems.","authors":"Payam E Farahani, Ellen H Reed, Evan J Underhill, Kazuhiro Aoki, Jared E Toettcher","doi":"10.1146/annurev-bioeng-083120-111648","DOIUrl":"https://doi.org/10.1146/annurev-bioeng-083120-111648","url":null,"abstract":"<p><p>Cells receive enormous amounts of information from their environment. How they act on this information-by migrating, expressing genes, or relaying signals to other cells-comprises much of the regulatory and self-organizational complexity found across biology. The \"parts list\" involved in cell signaling is generally well established, but how do these parts work together to decode signals and produce appropriate responses? This fundamental question is increasingly being addressed with optogenetic tools: light-sensitive proteins that enable biologists to manipulate the interaction, localization, and activity state of proteins with high spatial and temporal precision. In this review, we summarize how optogenetics is being used in the pursuit of an answer to this question, outlining the current suite of optogenetic tools available to the researcher and calling attention to studies that increase our understanding of and improve our ability to engineer biology.</p>","PeriodicalId":50757,"journal":{"name":"Annual Review of Biomedical Engineering","volume":"23 ","pages":"61-87"},"PeriodicalIF":9.7,"publicationDate":"2021-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436267/pdf/nihms-1915991.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10416147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 20

Physiological Modeling and Simulation-Validation, Credibility, and Application. 生理建模和仿真——验证、可信度和应用。

IF 9.7 1区工程技术

Annual Review of Biomedical Engineering Pub Date : 2020-06-04 DOI: 10.1146/annurev-bioeng-082219-051740

W Andrew Pruett, John S Clemmer, Robert L Hester

引用次数: 8

Sparse Data-Driven Learning for Effective and Efficient Biomedical Image Segmentation. 用于高效生物医学图像分割的稀疏数据驱动学习。

IF 9.7 1区工程技术

Annual Review of Biomedical Engineering Pub Date : 2020-06-04 Epub Date: 2020-03-13 DOI: 10.1146/annurev-bioeng-060418-052147

John A Onofrey, Lawrence H Staib, Xiaojie Huang, Fan Zhang, Xenophon Papademetris, Dimitris Metaxas, Daniel Rueckert, James S Duncan

引用次数: 4