Annual Review of Biomedical Engineering最新文献_第10页

Mechanobiology of Macrophages: How Physical Factors Coregulate Macrophage Plasticity and Phagocytosis. 巨噬细胞的机械生物学:物理因素如何共同调节巨噬细胞的可塑性和吞噬作用。

IF 9.7 1区工程技术

Annual Review of Biomedical Engineering Pub Date : 2019-06-04 DOI: 10.1146/annurev-bioeng-062117-121224

Nikhil Jain, Jens Moeller, Viola Vogel

{"title":"Mechanobiology of Macrophages: How Physical Factors Coregulate Macrophage Plasticity and Phagocytosis.","authors":"Nikhil Jain, Jens Moeller, Viola Vogel","doi":"10.1146/annurev-bioeng-062117-121224","DOIUrl":"https://doi.org/10.1146/annurev-bioeng-062117-121224","url":null,"abstract":"In addition to their early-recognized functions in host defense and the clearance of apoptotic cell debris, macrophages play vital roles in tissue development, homeostasis, and repair. If misregulated, they steer the progression of many inflammatory diseases. Much progress has been made in understanding the mechanisms underlying macrophage signaling, transcriptomics, and proteomics, under physiological and pathological conditions. Yet, the detailed mechanisms that tune circulating monocytes/macrophages and tissue-resident macrophage polarization, differentiation, specification, and their functional plasticity remain elusive. We review how physical factors affect macrophage phenotype and function, including how they hunt for particles and pathogens, as well as the implications for phagocytosis, autophagy, and polarization from proinflammatory to prohealing phenotype. We further discuss how this knowledge can be harnessed in regenerative medicine and for the design of new drugs and immune-modulatory drug delivery systems, biomaterials, and tissue scaffolds.","PeriodicalId":50757,"journal":{"name":"Annual Review of Biomedical Engineering","volume":"21 ","pages":"267-297"},"PeriodicalIF":9.7,"publicationDate":"2019-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-bioeng-062117-121224","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37044841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 121

New Sensor and Wearable Technologies to Aid in the Diagnosis and Treatment Monitoring of Parkinson's Disease. 新的传感器和可穿戴技术有助于帕金森病的诊断和治疗监测。

IF 9.7 1区工程技术

Annual Review of Biomedical Engineering Pub Date : 2019-06-04 DOI: 10.1146/annurev-bioeng-062117-121036

Mariana H G Monje, Guglielmo Foffani, José Obeso, Álvaro Sánchez-Ferro

引用次数: 64

Electrophysiological Source Imaging: A Noninvasive Window to Brain Dynamics. 电生理源成像:脑动力学的无创窗口。

IF 9.7 1区工程技术

Annual Review of Biomedical Engineering Pub Date : 2018-06-04 Epub Date: 2018-03-01 DOI: 10.1146/annurev-bioeng-062117-120853

Bin He, Abbas Sohrabpour, Emery Brown, Zhongming Liu

{"title":"Electrophysiological Source Imaging: A Noninvasive Window to Brain Dynamics.","authors":"Bin He, Abbas Sohrabpour, Emery Brown, Zhongming Liu","doi":"10.1146/annurev-bioeng-062117-120853","DOIUrl":"10.1146/annurev-bioeng-062117-120853","url":null,"abstract":"Brain activity and connectivity are distributed in the three-dimensional space and evolve in time. It is important to image brain dynamics with high spatial and temporal resolution. Electroencephalography (EEG) and magnetoencephalography (MEG) are noninvasive measurements associated with complex neural activations and interactions that encode brain functions. Electrophysiological source imaging estimates the underlying brain electrical sources from EEG and MEG measurements. It offers increasingly improved spatial resolution and intrinsically high temporal resolution for imaging large-scale brain activity and connectivity on a wide range of timescales. Integration of electrophysiological source imaging and functional magnetic resonance imaging could further enhance spatiotemporal resolution and specificity to an extent that is not attainable with either technique alone. We review methodological developments in electrophysiological source imaging over the past three decades and envision its future advancement into a powerful functional neuroimaging technology for basic and clinical neuroscience applications.","PeriodicalId":50757,"journal":{"name":"Annual Review of Biomedical Engineering","volume":"20 ","pages":"171-196"},"PeriodicalIF":9.7,"publicationDate":"2018-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-bioeng-062117-120853","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35874796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 144

Arterial Venous Differentiation for Vascular Bioengineering. 血管生物工程中的动静脉分化。

IF 9.7 1区工程技术

Annual Review of Biomedical Engineering Pub Date : 2018-06-04 Epub Date: 2018-04-11 DOI: 10.1146/annurev-bioeng-062117-121231

Laura Niklason, Guohao Dai

引用次数: 17

Energy-Based Tissue Fusion for Sutureless Closure: Applications, Mechanisms, and Potential for Functional Recovery. 无缝线闭合的能量组织融合:应用、机制和功能恢复的潜力。

IF 9.7 1区工程技术

Annual Review of Biomedical Engineering Pub Date : 2018-06-04 DOI: 10.1146/annurev-bioeng-071516-044702

Eric A Kramer, Mark E Rentschler

{"title":"Energy-Based Tissue Fusion for Sutureless Closure: Applications, Mechanisms, and Potential for Functional Recovery.","authors":"Eric A Kramer, Mark E Rentschler","doi":"10.1146/annurev-bioeng-071516-044702","DOIUrl":"https://doi.org/10.1146/annurev-bioeng-071516-044702","url":null,"abstract":"As minimally invasive surgical techniques progress, the demand for efficient, reliable methods for vascular ligation and tissue closure becomes pronounced. The surgical advantages of energy-based vessel sealing exceed those of traditional, compression-based ligatures in procedures sensitive to duration, foreign bodies, and recovery time alike. Although the use of energy-based devices to seal or transect vasculature and connective tissue bundles is widespread, the breadth of heating strategies and energy dosimetry used across devices underscores an uncertainty as to the molecular nature of the sealing mechanism and induced tissue effect. Furthermore, energy-based techniques exhibit promise for the closure and functional repair of soft and connective tissues in the nervous, enteral, and dermal tissue domains. A constitutive theory of molecular bonding forces that arise in response to supraphysiological temperatures is required in order to optimize and progress the use of energy-based tissue fusion. While rapid tissue bonding has been suggested to arise from dehydration, dipole interactions, molecular cross-links, or the coagulation of cellular proteins, long-term functional tissue repair across fusion boundaries requires that the reaction to thermal damage be tailored to catalyze the onset of biological healing and remodeling. In this review, we compile and contrast findings from published thermal fusion research in an effort to encourage a molecular approach to characterization of the prevalent and promising energy-based tissue bond.","PeriodicalId":50757,"journal":{"name":"Annual Review of Biomedical Engineering","volume":"20 ","pages":"1-20"},"PeriodicalIF":9.7,"publicationDate":"2018-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-bioeng-071516-044702","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36190280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 21

From Nanowarming to Thermoregulation: New Multiscale Applications of Bioheat Transfer. 从纳米加热到温度调节：生物热传递的多尺度新应用。

IF 9.7 1区工程技术

Annual Review of Biomedical Engineering Pub Date : 2018-06-04 DOI: 10.1146/annurev-bioeng-071516-044532

John C Bischof, Kenneth R Diller

{"title":"From Nanowarming to Thermoregulation: New Multiscale Applications of Bioheat Transfer.","authors":"John C Bischof, Kenneth R Diller","doi":"10.1146/annurev-bioeng-071516-044532","DOIUrl":"10.1146/annurev-bioeng-071516-044532","url":null,"abstract":"This review explores bioheat transfer applications at multiple scales from nanoparticle (NP) heating to whole-body thermoregulation. For instance, iron oxide nanoparticles are being used for nanowarming, which uniformly and quickly rewarms 50-80-mL (≤5-cm-diameter) vitrified systems by coupling with radio-frequency (RF) fields where standard convective warming fails. A modification of this approach can also be used to successfully rewarm cryopreserved fish embryos (∼0.8 mm diameter) by heating previously injected gold nanoparticles with millisecond pulsed laser irradiation where standard convective warming fails. Finally, laser-induced heating of gold nanoparticles can improve the sensitivity of lateral flow assays (LFAs) so that they are competitive with laboratory tests such as the enzyme-linked immunosorbent assay. This approach addresses the main weakness of LFAs, which are otherwise the cheapest, easiest, and fastest to use point-of-care diagnostic tests in the world. Body core temperature manipulation has now become possible through selective thermal stimulation (STS) approaches. For instance, simple and safe heating of selected areas of the skin surface can open arteriovenous anastomosis flow in glabrous skin when it is not already established, thereby creating a convenient and effective pathway to induce heat flow between the body core and environment. This has led to new applications of STS to increase or decrease core temperatures in humans and animals to assist in surgery (perioperative warming), to aid ischemic stress recovery (cooling), and even to enhance the quality of sleep. Together, these multiscale applications of nanoparticle heating and thermoregulation point to dramatic opportunities for translation and impact in these prophylactic, preservative, diagnostic, and therapeutic applications of bioheat transfer.","PeriodicalId":50757,"journal":{"name":"Annual Review of Biomedical Engineering","volume":"20 ","pages":"301-327"},"PeriodicalIF":9.7,"publicationDate":"2018-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568271/pdf/nihms-1021630.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36190880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Engineering the Mucus Barrier. 设计粘液屏障。

IF 9.7 1区工程技术

Annual Review of Biomedical Engineering Pub Date : 2018-06-04 DOI: 10.1146/annurev-bioeng-062117-121156

T L Carlson, J Y Lock, R L Carrier

引用次数: 88

Synthetic Biology: Immunotherapy by Design. 合成生物学:设计免疫疗法。

IF 9.7 1区工程技术

Annual Review of Biomedical Engineering Pub Date : 2018-06-04 Epub Date: 2018-01-18 DOI: 10.1146/annurev-bioeng-062117-121147

Jamie Brenner, Jang Hwan Cho, Nicole M L Wong, Wilson W Wong

引用次数: 23

Inorganic Nanomaterials for Soft Tissue Repair and Regeneration. 用于软组织修复和再生的无机纳米材料。

IF 9.7 1区工程技术

Annual Review of Biomedical Engineering Pub Date : 2018-06-04 Epub Date: 2018-04-05 DOI: 10.1146/annurev-bioeng-071516-044457

Russell Urie, Deepanjan Ghosh, Inam Ridha, Kaushal Rege

引用次数: 54

Facet Joints of the Spine: Structure-Function Relationships, Problems and Treatments, and the Potential for Regeneration. 脊柱小关节:结构-功能关系，问题和治疗，以及再生的潜力。

IF 9.7 1区工程技术

Annual Review of Biomedical Engineering Pub Date : 2018-06-04 Epub Date: 2018-03-01 DOI: 10.1146/annurev-bioeng-062117-120924

Siobhan A O'Leary, Nikolaos K Paschos, Jarrett M Link, Eric O Klineberg, Jerry C Hu, Kyriacos A Athanasiou

{"title":"Facet Joints of the Spine: Structure-Function Relationships, Problems and Treatments, and the Potential for Regeneration.","authors":"Siobhan A O'Leary, Nikolaos K Paschos, Jarrett M Link, Eric O Klineberg, Jerry C Hu, Kyriacos A Athanasiou","doi":"10.1146/annurev-bioeng-062117-120924","DOIUrl":"https://doi.org/10.1146/annurev-bioeng-062117-120924","url":null,"abstract":"The zygapophysial joint, a diarthrodial joint commonly referred to as the facet joint, plays a pivotal role in back pain, a condition that has been a leading cause of global disability since 1990. Along with the intervertebral disc, the facet joint supports spinal motion and aids in spinal stability. Highly susceptible to early development of osteoarthritis, the facet is responsible for a significant amount of pain in the low-back, mid-back, and neck regions. Current noninvasive treatments cannot offer long-term pain relief, while invasive treatments can relieve pain but fail to preserve joint functionality. This review presents an overview of the facet in terms of its anatomy, functional properties, problems, and current management strategies. Furthermore, this review introduces the potential for regeneration of the facet and particular engineering strategies that could be employed as a long-term treatment.","PeriodicalId":50757,"journal":{"name":"Annual Review of Biomedical Engineering","volume":"20 ","pages":"145-170"},"PeriodicalIF":9.7,"publicationDate":"2018-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-bioeng-062117-120924","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35874797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 49