Eye & Contact Lens-Science and Clinical Practice最新文献

{"title":"Synergistic Effect of Dual-Focus Soft Contact Lenses and 0.05% Atropine on Myopia Control in Children With Rapidly Progressing Myopia.","authors":"Hae Ri Yum, So Young Han, Shin Hae Park, Sun Young Shin","doi":"10.1097/ICL.0000000000001154","DOIUrl":"10.1097/ICL.0000000000001154","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this study was to evaluate the combined effect of dual-focus soft contact lenses (CLs) and 0.05% atropine in the control of myopia.</p><p><strong>Methods: </strong>A retrospective study was conducted on 142 myopic children aged 7 to 13 years. A single nightly instillation of 0.05% atropine at bedtime was prescribed if the rate of myopia progression exceeded -1.00 D/year. After 1 year of treatment, patients who exhibited myopia progression of more than 0.75 D/year or an increase in axial length of more than 0.25 mm/year were additionally treated with dual-focus soft CLs (MiSight) alongside 0.05% atropine (Combination group, n=71). By contrast, patients who showed myopia progression of less than 0.50 D/year and axial elongation of less than 0.20 mm/year continued treatment with 0.05% atropine only (Monotherapy group, n=71). Subjects in the combination group were further divided into high myopia and low/moderate myopia subgroups, using a cutoff of -6 D.</p><p><strong>Results: </strong>Myopia progression and axial elongation were significantly slower after the addition of dual-focus soft CLs to 0.05% atropine in the combination group ( P =0.001 and P =0.012, respectively). The combination group exhibited statistically significantly faster myopia progression than the monotherapy group before the addition of dual-focus soft CLs (both P <0.001), but no significant difference in myopia progression between the two groups was observed afterward ( P =0.504 and P =0.479, respectively). The inhibition of axial elongation was more pronounced in the low/moderate myopia group compared with the high myopia group ( P =0.028).</p><p><strong>Conclusions: </strong>The combination of dual-focus soft CLs and 0.05% atropine is an effective treatment strategy for controlling myopia in children with rapidly progressing myopia. The additive effect was greater in children with low/moderate myopia than in those with high myopia.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"92-97"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142773924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scleral Contact Lens Benefits for Myopic Patients With Regular Corneas: A Prospective Randomized Study.","authors":"Ruixue Liang, Na Li, Lin Liu, Bei Du, Eric Pazo, Ruihua Wei","doi":"10.1097/ICL.0000000000001151","DOIUrl":"10.1097/ICL.0000000000001151","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the impact of scleral contact lens (SL) wear on the visual quality and the ocular surface wettability in myopic patients with regular corneas.</p><p><strong>Methods: </strong>This prospective, randomized, controlled study enrolled a total of 80 myopes with regular corneas. Subjects were randomly allocated to wear SL or rigid corneal lens (RCL) for 3 months. The objective optical quality parameters were detected using the Optical Quality Analysis System-II, and the ocular surface wettability was assessed using the Keratograph 5M noninvasive ocular surface analyzer. The National Eye Institute 25-Item Visual Function Questionnaire and Ocular Surface Disease Index questionnaire were performed.</p><p><strong>Results: </strong>Both SL and RCL wear could obtain good best-corrected visual acuity. Strehl ratio, modulation transfer function cutoff frequency, objective scattering index, and Optical Quality Analysis System values (Optical Quality Analysis System values at 100%, 20%, and 9% contrasts) in the SL group significantly improved from baseline to the third month (both P <0.05), but not in the RCL group. At the third month, tear meniscus height and noninvasive tear break-up time showed a significant increase in the SL wearers from baseline (both P <0.05), but exhibited no significant changes in the RCL group. At the third month, SL wearers had significantly higher noninvasive tear break-up time compared with RCL wearers ( P <0.05). Besides, after 3-month SL wear, the National Eye Institute 25-Item Visual Function Questionnaire score and the Ocular Surface Disease Index score both remarkably improved from baseline (both P <0.05).</p><p><strong>Conclusion: </strong>Short-term SL wear could provide satisfactory visual quality, ocular comfort, and stable tear film for myopic patients.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"76-84"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Investigation of Short-Term Axial Elongation Control After Orthokeratology Lens Correction: Exploring Its Predictive Role in Long-Term Therapeutic Efficacy.","authors":"Xuemei Han, Feifei Li, Yu Zhang, Jinfei Tang","doi":"10.1097/ICL.0000000000001142","DOIUrl":"10.1097/ICL.0000000000001142","url":null,"abstract":"<p><strong>Objective: </strong>This study was developed with the goal of exploring the efficacy of orthokeratology (OK) as an approach to controlling axial length (AL) growth and identifying factors predictive of the long-term efficacy of this approach.</p><p><strong>Methods: </strong>This was a retrospective study that enrolled 157 myopic children 7 to 15 years of age undergoing OK correction for over 3 years. The short- and long-term effectiveness of this approach at 1 and 3 years post-OK correction, respectively, was assessed. All participants were classified into two groups based on whether they exhibited good or poor long-term efficacy outcomes. Measurements of changes in AL were made at baseline and at 1 and 3 years post-OK. Univariate analyses and binary logistic regression approaches were used to evaluate baseline age, baseline spherical equivalent refraction, baseline keratometry (K) values of flat and steep meridians, and short-term effectiveness with the goal of identifying predictors of long-term efficacy.</p><p><strong>Results: </strong>Univariate analyses led to the identification of significant differences in baseline age, baseline spherical equivalent refraction, baseline AL, and short-term efficacy between these two groups ( P <0.05), whereas gender, baseline flat K, and baseline steep K did not differ significantly ( P >0.05). In binary logistic regression analyses, baseline AL ( P =0.017) and short-term efficacy ( P <0.001) were both found to significantly influence long-term efficacy. Receiver operating characteristic curves demonstrated that short-term efficacy offered an area under the curve value >0.8, consistent with its highly accurate performance as a predictor of long-term efficacy.</p><p><strong>Conclusion: </strong>These results suggest that short-term efficacy outcomes can feasibly be used to predict the long-term effectiveness of OK correction in children. In patients exhibiting poor short-term efficacy, timely replacement or the incorporation of additional treatment modalities may aid efforts to better control the progression of myopia.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"85-91"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142548722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intrastromal Corneal Ring Segments and Keratoconus Progression: A Case Series Study.","authors":"Blanca Benito-Pascual, Pedro Arriola-Villalobos, Olivia Rodríguez-Quet, Vittoria Termine, Ricardo Cuiña-Sardiña, David Díaz-Valle","doi":"10.1097/ICL.0000000000001137","DOIUrl":"10.1097/ICL.0000000000001137","url":null,"abstract":"<p><strong>Objective: </strong>To assess keratoconus (KC) progression following the implant of intrastromal corneal ring segments (ICRSs) in young patients.</p><p><strong>Materials and methods: </strong>Retrospective, longitudinal, observational, controlled nonrandomized case series study. Keratoconus patients aged 25 years or younger who underwent uneventful ICRS surgery and completed at least 3 years of follow-up were enrolled. Controls were of similar age and treatment-naive patients with KC. The following Pentacam imaging (Oculus, Wetzlar, Germany) data were analyzed: keratometric (maximum, in-flattest meridian, in-steepest meridian, and mean), aberrometric (higher-order aberrations and coma), pachymetric (thinnest corneal thickness), and elevation (maximum posterior elevation). The main outcome measure was KC progression.</p><p><strong>Results: </strong>The study sample comprised 20 eyes of 18 cases (age 20.20 ± 3.70 years, nine right eyes, 14 male patients) and 30 eyes of 24 controls (age 20.80 ± 3.20 years, 15 right eyes, 21 male patients). The mean follow-up duration was 4.90 ± 1.70 years (range 3-8 years) for cases and 4.50 ± 1.40 years (range 3-8 years) for controls. Four cases and two controls met criteria for KC progression.</p><p><strong>Conclusions: </strong>Intrastromal corneal ring segments did not have significant impact on KC progression in the cohort.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"65-69"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142562994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Size Matters: A Comparative Study on Midday Fogging and Lens Settling in Patients With Keratoconus Wearing Mini-Scleral Lenses With Two Different Diameters.","authors":"Elif Bagatur Vurgun, Semra Akkaya Turhan, Ayşe Ebru Toker","doi":"10.1097/ICL.0000000000001135","DOIUrl":"10.1097/ICL.0000000000001135","url":null,"abstract":"<p><strong>Purpose: </strong>The objective of this study was to compare the changes in postlens fluid optical density, timing and quantity of lens settling, and the clinical performance between two different mini-scleral lenses.</p><p><strong>Methods: </strong>Seventeen eyes of 10 patients with keratoconus were fitted with a 15-mm mini-scleral lens (AirKone Scleral Lenses; Laboratoire LCS, Normandy, France), and 15 eyes of 10 patients with keratoconus were fitted with 16.5-mm mini-scleral lenses (Misa Lenses; Microlens Contactlens Technology, Arnhem, The Netherlands). The lens fit was evaluated with biomicroscopy and anterior segment optical coherence tomography (AS-OCT). At 0, 2, and 4 hrs, corneal clearances were measured with AS-OCT, and optical density measurements were made by Scheimpflug tomography. High-contrast visual acuity (HCVA) and contrast sensitivity (CS) were assessed at each time point. At the end of the 4th hour, participants' comfort, visual quality, and general satisfaction were evaluated with a 5-point Likert scale and 100-mm Visual Analog Scale (VAS) scale.</p><p><strong>Results: </strong>The mean age (24.4 ± 5.4 vs. 21.7 ± 4.5, P = 0.145) and best spectacle-corrected HCVA (0.36 ± 0.15 vs. 0.35 ± 0.20, P = 0.984) were similar in both groups. The mean Snellen HCVA significantly improved with dispensing both mini-scleral lenses and remained stable at 4 hrs in both groups. In comparison, CS significantly decreased at 4 hrs in both groups ( P = 0.02). Both groups' optical density significantly increased over time ( P = 0.003). In the 15-mm mini-scleral lens group, the settling amount was 62.2 ± 11.9 μm (62.6%) and 99.5 ± 14.2 μm (100%) at 2 and 4 hrs, respectively; in the 16.5-mm mini-scleral lens group, it was 46.4 ± 22.3 μm (56.4%) and 82.1 ± 37.3 μm (100%) at 2 and 4 hrs, respectively. More than 50% of settling occurred in the first 2 hrs in both groups. No significant difference was observed between the two groups with regard to visual acuity, CS, optical density, and total settling amount at 4 hrs ( P > 0.05). Patient in the 15-mm mini-scleral lens group scored higher in comfort (4.65 ± 0.7 vs. 3.60 ± 0.9), visual quality (4.76 ± 0.4 vs. 3.73 ± 0.7), and overall satisfaction (95.7 ± 6.0 vs. 65.3 ± 20.3) ( P < 0.0001).</p><p><strong>Conclusion: </strong>Patients reported a heightened level of contentment with the smaller-diameter lens; however, it is crucial to emphasize that both diameter scleral lenses showcase comparable clinical efficacy, midday fogging, and settling.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"53-57"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scleral Lens Use in the Management of Ocular Cicatricial Pemphigoid.","authors":"Boris Severinsky, Shae Chambers, Aysha Shafi, Soroosh Behshad, Joung Kim","doi":"10.1097/ICL.0000000000001172","DOIUrl":"https://doi.org/10.1097/ICL.0000000000001172","url":null,"abstract":"<p><strong>Purpose: </strong>Symptom management in Ocular Cicatricial Pemphigoid (OCP) is challenging because of the progressive factors of dry eye, scarring, trichiasis, and vision impairment. We set out to evaluate the benefits and therapeutic effects of scleral contact lenses in the management of OCP.</p><p><strong>Methods: </strong>A retrospective review was performed over a database of 20 patients (36 eyes) fitted with scleral lenses (SL) at the Department of Ophthalmology, Emory University from May 2018 to April 2021. The fitting indications, time required for ocular surface stabilization, vision rehabilitation success, and ocular complications were evaluated.</p><p><strong>Results: </strong>The mean age was 67.4 (range, 43-81) years, with four to one female to male predominance. The mean duration of the follow-up was 16.5 months (range, 1.5-35). The mean wearing time was 9.0±1.9 hr a day, with no overnight wear permitted. All fitted patients reported a subjective improvement in ocular comfort after initiations of SL wear. The mean keratopathy grading improved from 2.1±0.8 to 1.4±0.7 at the last documented visit. The mean visual acuity improved from 0.56±0.51 (logMAR) to 0.34±0.45; in 46% of patient eyes, visual acuity improved by two or more lines. And 96% of fitted eyes responded well to therapy and continued scleral lens wear. Patients who initially presented with fornix shortening, symblepharon, and trichiasis remained stable.</p><p><strong>Conclusions: </strong>SL offer ocular surface preservation, symptom relief, and improved visual acuity in patients with ocular pemphigoid. They should be strongly considered as ancillary therapy in patients with OCP.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143069463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Sneaky Culprit: Secondary Infectious Keratitis Due to Brevundimonas diminuta.","authors":"Suma K Thareja, Susan Luo, Sarah Carballo","doi":"10.1097/ICL.0000000000001170","DOIUrl":"https://doi.org/10.1097/ICL.0000000000001170","url":null,"abstract":"<p><strong>Purpose: </strong>To describe a rare case of infectious keratitis secondary to Brevundimonas diminuta, a gram-negative bacillus with fluoroquinolone resistance and rare clinical isolation.</p><p><strong>Methods: </strong>A 50-year-old man with contact lens overuse presented with a large corneal ulcer and hand motion visual acuity. Initial treatment with fortified topical tobramycin and vancomycin yielded slow improvement, and initial culture grew Staphylococcus epidermidis, Staphylococcus hominis, and Corynebacterium bovis. Therapy was tapered to topical moxifloxacin. Loteprednol was added to reduce corneal inflammation after presumed sterilization. Persistent epithelial defect and worsening infiltrate after 3 weeks prompted repeat culture and corneal punch biopsy.</p><p><strong>Results: </strong>Repeat culture revealed B. diminuta resistant to moxifloxacin. Treatment was modified to tobramycin, and therapeutic penetrating keratoplasty was pursued to prevent further stromal loss. Four months postoperatively, the cornea remained clear without recurrence or neovascularization.</p><p><strong>Conclusion: </strong>To our knowledge, this is the second reported culture-positive case of secondary infectious keratitis with B. diminuta, highlighting its rarity and potential for delayed identification. The atypical response to initial therapy underscores the importance of repeat cultures and corneal biopsy in persistent cases. This case contributes to the growing understanding of rare ocular pathogens, advocating for a vigilant clinical approach.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Cataract Surgery on Stereoacuity, Balance, and Falls in Patients With Senile Cataract.","authors":"Ömer Özer, Özer Dursun, Pınar Eroz, Emin Serbülent Guclu","doi":"10.1097/ICL.0000000000001168","DOIUrl":"https://doi.org/10.1097/ICL.0000000000001168","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate the effect of cataract surgery on visual acuity, stereoacuity, balance, and falls in patients with senile cataract.</p><p><strong>Methods: </strong>Prospective, cross-sectional study. The patients were divided into group 1 if the first surgery was performed on the dominant eye and group 2 on the nondominant eye. After a complete ophthalmologic examination, all patients underwent stereoacuity tests (Titmus and TNO test); Berg Balance Scale and the number of falls in the last 36 months were recorded. All assessments were performed at three time points: the preoperative period, 6 months after the first surgery (primary endpoint), and 24 months after the second surgery (secondary endpoint).</p><p><strong>Results: </strong>The mean number of falls was 4.95±2.6/year in the preoperative period and 1.43±0.59/year in the postoperative period. The incidence of falls after the second surgery decreased by 53.15% compared with the preoperative period. The number of falls and preoperative stereoacuity were negatively and moderately correlated (r=-0.546) (P=0.033). In univariate and multivariate analysis, only low preoperative corrected distance visual acuity in the dominant eye was associated with poor stereoacuity (P=0.001) and a high number of falls (P<0.001) in the preoperative period.</p><p><strong>Conclusion: </strong>Cataract surgery in patients with senile cataracts not only improves visual acuity but also increases stereoacuity level, improves balance, and decreases falls. These effects should be further studied in multicenter, large-participant studies.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143034638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Topographical and Refractive Outcomes After Corneal Cross-linking in Novice Scleral Lens Users.","authors":"Faith Aisien, Laura Di Meglio, Kraig Bower, Amanda Crum","doi":"10.1097/ICL.0000000000001166","DOIUrl":"https://doi.org/10.1097/ICL.0000000000001166","url":null,"abstract":"<p><strong>Objective: </strong>To determine if scleral fittings that occur before corneal cross-linking (CXL) are still successful after the procedure.</p><p><strong>Methods: </strong>This prospective study included seven patients with keratoconus or post-laser-assisted in situ keratomileusis (LASIK) corneal ectasia who were fitted with scleral lenses then underwent CXL. Four patients (six eyes) had keratoconus and three patients (five eyes) had post-LASIK ectasia. Topographic and refractive parameters, as well as uncorrected visual acuity, best spectacle-corrected visual acuity, and scleral lens-corrected visual acuity were collected preoperatively and compared with values 1 and 3 months postoperatively.</p><p><strong>Results: </strong>Ten eyes had no significant change in refractive parameters from baseline to 3 months (P>0.05). Nine eyes had no significant change in Km (mean keratometry), K2 (steep keratometry), Kmax (maximal corneal curvature), or pachymetry from baseline to 3 months (P>0.05). On average, there was no significant difference regarding scleral lens or topographic measurements preoperatively versus postoperatively (P>0.05).</p><p><strong>Conclusion: </strong>On average, no significant differences were observed between preoperative and postoperative corneal measurements or refractive correction. These findings suggest that scleral fittings could be introduced before CXL to expedite the process of lens prescription and future acquisition. Safe scleral lens use with a lens fit before surgery could resume 1 month postoperatively.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143024845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Double Povidone-Iodine 5% Preparation Before Cataract Surgery for Endophthalmitis Prevention.","authors":"Jamie L Odden, Jacob Winters, Leonid Zlotcavitch, Alex Mammen, Eric G Romanowski, Robert M Q Shanks, Deepinder K Dhaliwal","doi":"10.1097/ICL.0000000000001164","DOIUrl":"https://doi.org/10.1097/ICL.0000000000001164","url":null,"abstract":"<p><strong>Objective: </strong>To compare endophthalmitis rates after cataract extraction in patients with different preoperative prophylaxis: double povidone-iodine preparation with topical antibiotics versus a control group.</p><p><strong>Methods: </strong>All cases of postoperative endophthalmitis over the last 17 years were reviewed. Incidence rates of endophthalmitis for all cataract surgeries (current procedural terminology codes 66982 and 66984) performed by 26 surgeons were calculated. Cataract surgery combined with glaucoma and corneal procedures were excluded (1,347 surgeries). Incidence rates were compared for the study group (i.e., use of double povidone-iodine preparation) versus the control group. In the study group, two standard interventions were implemented: preoperative instillation of fluoroquinolone drops every 15 min for 1 hr and preoperative irrigation of conjunctival fornices and eyelashes with 10 cc of 5% povidone-iodine. In both the study and control group, povidone-iodine preparation was performed in the operating room, and postoperative fluoroquinolone drops were used.</p><p><strong>Results: </strong>From January 2005 to May 2022, no cases of endophthalmitis were identified out of 7,611 cataract extractions performed by three surgeons who used the double povidone-iodine preparation. Seven new cases of endophthalmitis were identified in the control group during the same time (7 out of 9,876=0.07%). Two of these cases had combined cataract surgery with endoscopic cyclophotocoagulation, and five cases had cataract surgery alone. Individual surgeon rates of endophthalmitis ranged from 0% to 0.29%.</p><p><strong>Conclusion: </strong>A double povidone-iodine preparation may provide more robust prophylaxis against postcataract extraction endophthalmitis than a single preparation.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}