Eye & Contact Lens-Science and Clinical Practice最新文献

{"title":"Recognizing Ocular Milker's Nodule: Diagnostic Clues and Clinical Course in Two Dairy Workers.","authors":"Laxmi Ahir, Nikhil Agrawal, Nidhi Paharia","doi":"10.1097/ICL.0000000000001301","DOIUrl":"10.1097/ICL.0000000000001301","url":null,"abstract":"<p><strong>Abstract: </strong>Milker's nodule is a zoonotic infection caused by the Parapoxvirus (genus Parapoxvirus , family Poxviridae ), typically affecting dairy workers through direct contact with infected cattle. Ocular involvement is rare and usually results from autoinoculation from hand lesions. We report two cases in dairy workers presenting with vesiculoulcerative eyelid lesions and corneal epithelial defects. One patient developed limbitis and stromal keratitis, which resolved completely with topical lubricants, and corticosteroids after reepithelialization. The second case healed spontaneously with conservative therapy. Ocular Milker's nodule closely mimics viral keratitis but follows a benign, self-limiting course. Recognition of characteristic hand lesions and occupational exposure is essential for accurate diagnosis and to avoid unnecessary antiviral therapy. Preventive measures include glove use, hand hygiene, and cattle vaccination.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"387-389"},"PeriodicalIF":2.2,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148406676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Extremely Rare and Devastating Complication of Penetrating Keratoplasty: Postoperative Endophthalmitis Because of Carbapenem-Resistant Klebsiella pneumoniae.","authors":"Kubra Sincar, Oguz Reşat Sipahi, Mervenur Kanat, Sabire Sohret Aydemir, Canan Bor, Melis Palamar, Naim Ceylan, Banu Yaman, Mesut Arici, Ozlem Barut Selver","doi":"10.1097/ICL.0000000000001287","DOIUrl":"10.1097/ICL.0000000000001287","url":null,"abstract":"<p><strong>Abstract: </strong>To report the second case report in the literature of early-onset endophthalmitis caused by carbapenem-resistant Klebsiella pneumoniae (CRKP) after penetrating keratoplasty (PK). The associated diagnostic and therapeutic challenges are highlighted, and the precautions that can be applied are emphasized. A 69-year-old woman with bullous keratopathy underwent elective PK. Within 24 hr postoperatively, stromal infiltration and partial separation at the superior quadrant of the graft and anterior chamber reaction were observed. Urgent rekeratoplasty was performed, and microbiologic culture of the donor tissue revealed extensively drug-resistant CRKP resistant to multiple antibiotics. Despite rapid surgical revision and intensive antimicrobial therapy (topical, intrastromal, intravitreal, and systemic), the infection progressed to orbital cellulitis and systemic involvement, ultimately requiring evisceration. Carbapenem-resistant Klebsiella pneumoniae was also isolated from the excised globe. Donor-derived contamination was strongly suspected because of the early clinical course but could not be confirmed microbiologically because the donor margin tissue was not preserved. Furthermore, retrospective medical data review of the donor did not reveal any similar microorganism and clinical follow-up of PK from the other corneal partner showed no infection. This case constitutes the second documented instance of CRKP-related endophthalmitis after PK in the literature. It emphasizes the importance of donor screening, continuous monitoring of the storage environment, preservation of donor margin tissue, and vigilant monitoring for systemic dissemination and severe postoperative complications.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"382-386"},"PeriodicalIF":2.2,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148044691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving Ophthalmology Resident Knowledge of Contact Lens Science and Practice: Early Experience With a Structured Online Curriculum.","authors":"Minwoo Kwon, Khushali Shah, Sumayya Ahmad, Michelle K Rhee","doi":"10.1097/ICL.0000000000001298","DOIUrl":"10.1097/ICL.0000000000001298","url":null,"abstract":"","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":"52 9","pages":"394"},"PeriodicalIF":2.2,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148800723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of a Prostaglandin Analog-Based Eyelash Serum on Tear Film Stability and the Ocular Surface.","authors":"José-María Sánchez González, Margarita Gandullo-Asuar, Antonio Ballesteros Sánchez, María C Sánchez-González, Julia Hernández-Lucena, Raúl Capote-Puente, Concepción De-Hita-Cantalejo, Carlos Rocha-de-Lossada","doi":"10.1097/ICL.0000000000001300","DOIUrl":"10.1097/ICL.0000000000001300","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to evaluate the short-term effect of a prostaglandin analog-based eyelash serum on the ocular surface.</p><p><strong>Methods: </strong>A prospective interventional study was conducted on 19 healthy women. Participants applied an eyelash serum containing dechloro dihydroxy difluoro ethylcloprostenolamide once daily to the upper eyelid margin for 6 weeks. Tear film parameters, meibomian glands analysis, and ocular surface inflammation and damage were assessed at baseline and posttreatment using the S390L slit lamp (Firefly WDR, MediWorks, Shanghai, China).</p><p><strong>Results: </strong>A significant reduction in tear film stability was observed, with decreases of 3.92±7.45 sec in first noninvasive break-up time ( P =0.003) and 3.97±6.25 sec in average noninvasive break-up time ( P <0.001). Tear volume was reduced, as shown by decreases of 0.01±0.04 mm in tear meniscus height ( P =0.049) and 0.27±0.66 mm 2 in tear meniscus area ( P =0.019). Ocular hyperemia increased, with temporal ciliary hyperemia rising by 1.68±3.45% ( P =0.006) and temporal conjunctival hyperemia by 2.41±4.14% ( P =0.001). No statistically significant changes were observed in meibomian gland morphology or ocular surface staining.</p><p><strong>Conclusions: </strong>Daily application of the prostaglandin analog-based eyelash serum induced tear film instability, reduced tear volume, and increased ocular hyperemia. These findings suggest that even short-term use may disrupt ocular surface homeostasis and cause mild inflammation. Further studies with longer follow-up are needed to assess its safety profile on the ocular surface.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"368-374"},"PeriodicalIF":2.2,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148708400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Agreement of Corvis ST Biomechanical IOP Measurements With Pachymetry-Based Correction Formulas in Patients With Keratoconus: A Comparative Analysis According to Disease Severity.","authors":"Fahri Onur Aydın, Ali Ceylan, Yusuf Berk Akbaş, İdil Çelen Arabacı, Serhat Ermiş, Burçin Kepez Yıldız","doi":"10.1097/ICL.0000000000001284","DOIUrl":"10.1097/ICL.0000000000001284","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the agreement of intraocular pressure (IOP) measurements obtained by Corvis ST using biomechanically corrected IOP (bIOP), noncontact tonometry (NCT), and pachymetry-based correction formulas (Ehlers, Shah, Dresden, Spoerl) across different keratoconus severity levels and in comparison with healthy control eyes.</p><p><strong>Methods: </strong>This prospective, cross-sectional study included 77 patients with keratoconus (77 eyes), categorized by severity using Pentacam-based Topographic Keratoconus Classification and 54 healthy control patients. Patients underwent corneal tomography, and IOP was measured with Corvis ST. Uncorrected NCT-IOP (IOPnct), biomechanically corrected IOP (bIOP), and pachymetry-based corrected IOP (Ehlers, Shah, Dresden, Spoerl) were compared. Agreement among methods was assessed using Bland-Altman analysis.</p><p><strong>Results: </strong>The mean patient age was 26.4±7.3 years (59.7% male). NCT consistently underestimated IOP compared with bIOP, while Ehlers (+2.6 mm Hg), Shah (+1.4 mm Hg), and Dresden (+0.7 mm Hg) formulas significantly overestimated ( P <0.001). The Spoerl formula (-0.9 mm Hg) showed no significant difference compared with bIOP ( P =0.209). Bland-Altman analysis confirmed that the Spoerl formula had the smallest bias and narrowest limits of agreement across all keratoconus stages. Differences between methods became more pronounced with increasing severity, particularly evident for Ehlers and Shah formulas. In healthy control eyes, the different IOP estimation methods showed relatively small bias relative to bIOP.</p><p><strong>Conclusions: </strong>Noncontact tonometry significantly underestimates, and common pachymetry-based corrections (Ehlers, Shah, Dresden) tend to overestimate IOP in keratoconic eyes. The Spoerl formula provides IOP values most closely aligned with the Corvis ST bIOP across all keratoconus stages and was the most consistent pachymetric correction method relative to this biomechanically corrected comparator. Agreement between methods was closer in healthy corneas than in keratoconic eyes, supporting the influence of altered corneal biomechanics on tonometric measurements.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"362-367"},"PeriodicalIF":2.2,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147965187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sjögren Disease and the Corneal Surface.","authors":"Reiko Kobayashi, Shizuka Koh","doi":"10.1097/ICL.0000000000001261","DOIUrl":"10.1097/ICL.0000000000001261","url":null,"abstract":"<p><strong>Abstract: </strong>Dry eye in Sjögren disease is characterized by lacrimal gland dysfunction, often resulting in decreased lacrimal fluid secretion, tear film thinning, epithelial cell damage, and ocular surface inflammation. Beyond lacrimal gland impairment, corneal nerves play a crucial role in the disease, with patients exhibiting a spectrum of symptoms depending on structural and functional nerve abnormalities. Two phenotypes are recognized in patients with Sjögren disease: one with diminished symptoms despite worsening clinical signs (neurotrophic aspect), and another with heightened symptoms such as hyperalgesia or photoallodynia that are disproportionate to clinical findings (neuropathic aspect). A comprehensive understanding of corneal nerve status may enable more personalized treatment approaches.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"328-331"},"PeriodicalIF":2.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146127051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corneal Sensitivity Recovery After Eyelid Malposition Surgery: A Clinical Perspective.","authors":"Francisco Calleja-Casado, Amparo Lanuza García, Sergio Obiol Ferrando, Elena Navarro Hernández, Antonio Miguel Duch Samper","doi":"10.1097/ICL.0000000000001280","DOIUrl":"10.1097/ICL.0000000000001280","url":null,"abstract":"","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"347"},"PeriodicalIF":2.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147876263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ocular Neuropathic Pain: A Clinician's Approach.","authors":"Deborah S Jacobs","doi":"10.1097/ICL.0000000000001295","DOIUrl":"10.1097/ICL.0000000000001295","url":null,"abstract":"<p><strong>Abstract: </strong>Ocular neuropathic pain (ONP) can be defined as \"pain\" or \"discomfort\" projected to eye because of a lesion or disease or physiological dysfunction of the nervous system. The diagnosis of ONP is a clinical one; history, eye examination, the anesthetic challenge, and in vivo confocal microscopy providing supportive roles in helping to distinguish nociceptive, nociplastic, and neuropathic pain. Multimodal treatment involving local agents and interventions, along with systemic agents, is often required.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"338-342"},"PeriodicalIF":2.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148303816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neurotrophic Keratopathy in Herpes Zoster Ophthalmicus.","authors":"Bennie H Jeng","doi":"10.1097/ICL.0000000000001252","DOIUrl":"10.1097/ICL.0000000000001252","url":null,"abstract":"<p><strong>Abstract: </strong>Neurotrophic keratopathy (NK) is a serious condition that can lead to significant visual morbidity. One of the greatest challenges of treating NK is that there are a wide variety of underlying conditions that affect the corneal nerves, and the root cause of the NK for any given individual is necessary in order to provide the best possibility of treatment success. NK is noted to be frequently caused by herpetic disease, including herpes zoster ophthalmicus (HZO), and studies have demonstrated that the risk of developing NK increases with recurrences of HZO. As such, vaccination to prevent HZO, as well as suppressive valacyclovir to reduce the chance of multiple recurrences of HZO in individuals who have had HZO, can decrease the risk of NK from HZO as well as the subsequent vision loss. These preventative therapies are therefore highly recommended.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"324-327"},"PeriodicalIF":2.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145811974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hidden in Plain Sight: The Miscoding of Chronic Postsurgical Pain as Dry Eye Disease.","authors":"Nathan Goturi, Deborah S Jacobs, Eric A Moulton","doi":"10.1097/ICL.0000000000001285","DOIUrl":"10.1097/ICL.0000000000001285","url":null,"abstract":"<p><strong>Abstract: </strong>Chronic postsurgical pain (CPSP) is a complication of cataract surgery. It is underrecognized and may be misdiagnosed as dry eye disease (DED). This retrospective case series presents three patients with no history of DED who developed CPSP after cataract surgery, but were misdiagnosed with DED for months or years. Despite these patients continuing to complain of persistent eye pain, their symptoms were dismissed as DED, delaying appropriate management. These cases highlight the challenges in recognizing CPSP and detrimental consequences of misdiagnosis as DED. In addition, these cases demonstrate that International Classification of Diseases codes for DED can serve as proxies allowing retrospective identification and investigation of CPSP in large databases, which in turn, may contribute to identification of risk factors, improved use of resources, and better outcomes for patients with CPSP after cataract surgery.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"343-346"},"PeriodicalIF":2.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147965198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}