Mukaddes Damla Ciftci, Cumali Degirmenci, Melis Palamar
{"title":"Evaluation of Scleral Thickness in Patients With Keratoconus.","authors":"Mukaddes Damla Ciftci, Cumali Degirmenci, Melis Palamar","doi":"10.1097/ICL.0000000000001169","DOIUrl":"https://doi.org/10.1097/ICL.0000000000001169","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate scleral thickness of patients with keratoconus by anterior segment optical coherence tomography (AS-OCT).</p><p><strong>Materials and methods: </strong>Fifty-two eyes of 42 patients with keratoconus (group 1) and 42 right eyes of 42 healthy individuals (group 2) were included. Scleral thickness measurements were taken with AS-OCT 6, 4, and 2 mm behind the scleral spur in four gaze positions: superior, inferior, temporal, and nasal. The data including central corneal thickness (CCT) by Pentacam from patients with keratoconus was also analyzed and its relationship with scleral thickness was evaluated.</p><p><strong>Results: </strong>In group 1, mean scleral thickness from 6 mm posterior to scleral spur in superior, inferior, temporal, and nasal quadrants were 397±35.3 (320-482), 408±29.5 (341-467), 393±40.8 (297-469), and 403±35.8 (310-482) μm, respectively. In group 2, mean scleral thickness from 6 mm posterior to scleral spur in superior, inferior, temporal, and nasal quadrants were 440±42.2 (346-552), 461±33.9 (390-563), 451±46.6 (340-549) and 448±34.3 (350-521) μm, respectively. The mean scleral thickness in group 1 was significantly lower in all quadrants compared with group 2 (P<0.001). The mean CCT in group 1 was 478.22±87.55 (306-632) μm. Positive correlation was found between scleral thickness measurements taken at 4 mm (ϱ=0.312, P=0.037) and 2 mm (ϱ=0.308, P=0.039) posterior from the scleral spur in the inferior quadrant and CCT.</p><p><strong>Conclusion: </strong>Scleral thickness was significantly lower in patients with keratoconus. Scleral thickness and CCT were positively correlated in inferior quadrant. Even though it is not yet known whether scleral changes are progressive or not, scleral thickness measurement may also find a place in the diagnosis and follow-up of patients with keratoconus in the future.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Drug Delivery in PROSE Device as Alternative to Frequent Drop Administration in Severe Ocular Surface Disease.","authors":"Yandong Bian, Deborah S Jacobs","doi":"10.1097/ICL.0000000000001163","DOIUrl":"https://doi.org/10.1097/ICL.0000000000001163","url":null,"abstract":"<p><strong>Abstract: </strong>The design of the prosthetic replacement of the ocular surface ecosystem (PROSE) device allows it to serve as a novel drug delivery system. In this article, we describe the off-label administration of amphotericin B and cenegermin by instillation in the PROSE device reservoir for the treatment of Candida keratitis in the setting of a persistent epithelial defect.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hiroshi Toshida, Akiko Matsuzawa, Shizuka Koh, Yuichi Hori
{"title":"History of Lens Care Products in Japan: Insights From Advertisements in the Journal of the Japan Contact Lens Society for 65 Years.","authors":"Hiroshi Toshida, Akiko Matsuzawa, Shizuka Koh, Yuichi Hori","doi":"10.1097/ICL.0000000000001147","DOIUrl":"https://doi.org/10.1097/ICL.0000000000001147","url":null,"abstract":"<p><strong>Abstract: </strong>This review examines the history of contact lens (CL) care products, particularly focusing on hard contact lenses (HCLs) like those made from polymethyl methacrylate and rigid gas permeable (RGP) materials. Although literature on CL history is extensive, there is limited information on the history of CL care products, especially in Japan. This review uses advertisements from the Journal of the Japan Contact Lens Society from 1959 to 2023 to trace the evolution of these products. The early HCL care primarily involved simple cleaning with dishwashing liquids because of the robust nature of polymethyl methacrylate lenses. Advertisements for care products became more prevalent with the introduction of RGP lenses that are more prone to dirt and deposit buildup. The first significant advertisements for HCL care products appeared in 1968, with notable products highlighting advancements in cleaning, rinsing, and storing solutions. The introduction of soft contact lenses in Japan in 1972 necessitated new care methods, such as boiling disinfection. Over the years, the market saw the introduction of various multipurpose solutions and specialized cleaning agents, although the number of advertisements for these products has declined since the late 1990s. Economic factors and changes in the CL industry have influenced the advertising trends observed in the journal. Despite the decline in market share for RGP lenses, they remain essential for specific conditions like keratoconus, some corneal disorders with irregular astigmatism, and moderate to high astigmatism. This review underscores the ongoing need for effective CL care products and the role of advertisements in documenting their history.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":"50 12","pages":"522-526"},"PeriodicalIF":2.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11593975/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The History and Impact of Prescribing Orthokeratology for Slowing Myopia Progression.","authors":"Michael J Lipson, Bruce H Koffler","doi":"10.1097/ICL.0000000000001123","DOIUrl":"10.1097/ICL.0000000000001123","url":null,"abstract":"<p><strong>Abstract: </strong>This paper discusses the history and impact of orthokeratology on slowing the progression of myopia. It discusses the origins and evolution of orthokeratology from polymethymethaccrylate lenses worn during the day to its current prescribing of highly permeable, innovative reverse-geometry designs worn only while sleeping. Technological advances in corneal topography, lens design, lens materials, and manufacturing have facilitated growth of orthokeratology to a precise and predictable procedure. More recently, significant interest in orthokeratology has been stimulated by its efficacy in slowing axial elongation in myopic children. Safety of children wearing contact lenses while sleeping has been an ongoing concern. The potential of serious complications exists, but long-term studies and clinical experience have shown that risks of those events can be minimized with strict compliance with lens cleaning, disinfection, and hand hygiene. Because no correction is required during waking hours, patients using orthokeratology report higher vision-related quality of life, less activity restrictions, and more comfortable eyes compared with spectacles or contact lenses worn during the day. The future growth of orthokeratology will be fueled by the prescribing of orthokeratology as a modality to slow axial elongation and an alternative modality to spectacles, traditional contact lenses, and refractive surgery to correct refractive error.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"517-521"},"PeriodicalIF":2.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142299994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Eye & Contact Lens: Origins and Evolution of this Journal.","authors":"Joann J Kang, S Lance Forstot","doi":"10.1097/ICL.0000000000001127","DOIUrl":"https://doi.org/10.1097/ICL.0000000000001127","url":null,"abstract":"","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":"50 12","pages":"502-504"},"PeriodicalIF":2.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kayleigh M Risser, Melody Y Zhou, Karl G Koster, Felicia I Tejawinata, Xinyu Gu, Thomas L Steinemann
{"title":"Contact Lens Regulation: Where Have We Been, Where are We Going?","authors":"Kayleigh M Risser, Melody Y Zhou, Karl G Koster, Felicia I Tejawinata, Xinyu Gu, Thomas L Steinemann","doi":"10.1097/ICL.0000000000001148","DOIUrl":"10.1097/ICL.0000000000001148","url":null,"abstract":"<p><strong>Abstract: </strong>The Food and Drug Administration and the Federal Trade Commission influence the contact lens (CL) market, with the Food and Drug Administration regulating CLs as medical devices and the Federal Trade Commission dictating how they are prescribed and sold. Legislative oversight came to the forefront in 2004, when the Contact Lens Rule was introduced, drastically changing how CLs are prescribed and distributed. This article examines the evolution of CL regulations over the past two decades and discusses how regulation, such as allowing passive verification, has shaped the current and evolving CL market. We also explore how related products (decorative CLs, artificial tears) are regulated and compare US regulations with those abroad. Finally, we discuss how future technological advancements, including artificial intelligence, promise to change the CL industry and its regulation worldwide.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"508-516"},"PeriodicalIF":2.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Klaus Ehrmann, Cristian Talens-Estarelles, Fiona Stapleton, Brenda Truong, Jessica Chen, Blanka Golebiowski
{"title":"A New Method to Measure Ocular Surface Sensitivity: Repeatability and Reproducibility of the Liquid Jet Esthesiometer.","authors":"Klaus Ehrmann, Cristian Talens-Estarelles, Fiona Stapleton, Brenda Truong, Jessica Chen, Blanka Golebiowski","doi":"10.1097/ICL.0000000000001146","DOIUrl":"https://doi.org/10.1097/ICL.0000000000001146","url":null,"abstract":"<p><strong>Objectives: </strong>To assess the reliability of the liquid jet esthesiometer (LJA) for measurement of corneal sensitivity.</p><p><strong>Methods: </strong>Two separate studies were conducted to assess intrasession repeatability (study 1) and intersession reproducibility (study 2) of corneal sensitivity measured using the LJA. Thirty participants (13 female and 17 male participants, age 23±6 years) participated in study 1 and another 30 (18 female and 12 male participants, 35±10 years) participated in study 2. For study 1, mechanical sensation threshold of the central cornea was measured three times on the same day, with a 30-min break between repeats. For study 2, central corneal sensation threshold was measured on five different days by one of eight randomly assigned examiners.</p><p><strong>Results: </strong>Corneal sensation thresholds obtained in studies 1 and 2 were 2.3±1.0 and 2.5±1.2 μL, respectively. No significant differences between repeated measurements were obtained in either study (P≥0.19). Thresholds were lower (i.e., corneal sensitivity was higher) in female than male participants (2.1±1.0 vs. 2.7±0.9 μL in male participants, P=0.02) but were not affected by contact lens wear. Clinical reliability of the LJA was good for intrasession repeatability (coefficient of repeatability ±1.6 μL, intraclass correlation coefficient 0.74, within-subject coefficient of variation (CVW) 24%) and moderate for intersession reproducibility (Coefficient of Reproducibility ±2.2 μL, CVW 32%). Measurement variability was independent of threshold level (P=0.84).</p><p><strong>Conclusions: </strong>The LJA offers good clinical repeatability and is a reliable tool to measure corneal sensitivity in different population groups, regardless of stimulus thresholds. Day-to-day fluctuations in corneal sensitivity probably account for the relatively lower reproducibility.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sohum Sheth, Shawn Khan, April Olson, Lauren Jeang, Sonal Tuli, Ankit Shah
{"title":"Evaluation of Cyanoacrylate Tissue Adhesive Glue Application Outcomes in Corneal Thinning and Perforation.","authors":"Sohum Sheth, Shawn Khan, April Olson, Lauren Jeang, Sonal Tuli, Ankit Shah","doi":"10.1097/ICL.0000000000001144","DOIUrl":"10.1097/ICL.0000000000001144","url":null,"abstract":"<p><strong>Objectives: </strong>Corneal thinning and perforation are ocular emergencies necessitating urgent intervention to prevent visual impairment or enucleation. Cyanoacrylate tissue adhesive is frequently used to maintain globe integrity in these cases. However, gaps remain in understanding the outcomes of corneal gluing and the factors influencing its efficacy. This case series evaluates the clinical characteristics and outcomes of glue application in corneal thinning and perforation.</p><p><strong>Methods: </strong>A retrospective chart review was conducted on patients treated for corneal thinning and perforation at the University of Florida between January 2012 and May 2023. Demographic data, clinical history, glue application details, and posttreatment outcomes were collected and analyzed.</p><p><strong>Results: </strong>The study included 128 eyes from 125 subjects. Corneal perforation was found in 71 eyes (55.5%), mostly centrally (49.2%). The leading cause of perforation/thinning was microbial infection (45.3%). The average number of glue applications per eye was 1.66. Within 1 month, 23 patients (18.0%) required only glue reapplication, 37 (28.9%) required surgical intervention (regardless of glue reapplication), and 68 (53.1%) required no further treatment. Factors significantly linked to gluing failure (requiring surgery within 1 month) in univariate analysis included large perforation size, microbial infection, ocular surface disorder, single glue application, and indirect application via sterile drape. Multivariate analysis showed that only large perforation size was significantly associated with gluing failure.</p><p><strong>Conclusion: </strong>Corneal glue application is an effective temporizing measure for corneal thinning and perforation, with multiple applications potentially providing added stability to the globe. However, the need for surgical intervention is high.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}