Eye & Contact Lens-Science and Clinical Practice最新文献

{"title":"Quality of Life Survey Using NEI VFQ-25 in Japanese Patients With Fuchs Endothelial Corneal Dystrophy.","authors":"Keiko Yamada, Yoshinori Oie, Nozomi Nishida, Sayo Maeno, Chifune Kai, Masahiro Kitao, Reiko Kobayashi, Takeshi Soma, Shizuka Koh, Ryo Kawasaki, Kohji Nishida","doi":"10.1097/ICL.0000000000001159","DOIUrl":"10.1097/ICL.0000000000001159","url":null,"abstract":"<p><strong>Objectives: </strong>To assess the quality of life in Japanese patients with Fuchs endothelial corneal dystrophy (FECD) using The National Eye Institute Visual Function Questionnaire.</p><p><strong>Methods: </strong>Here, 34 patients with FECD (FECD group) and 13 healthy individuals (control group) completed the National Eye Institute Visual Function Questionnaire Japanese version by interview format. The association between dominant eye corrected distance visual acuity and composite score (component 11) or subscales in the FECD group was evaluated using Spearman rank correlation coefficient.</p><p><strong>Results: </strong>The average age was 65.8±11.9 and 60.1±7.9 years in the FECD and control groups, respectively. Corrected distance visual acuity was significantly lower in the FECD group (0.021±0.21 logarithm of the minimum angle of resolution) than in the control group (-0.61±0.055 logarithm of the minimum angle of resolution) ( P <0.0001). Composite scores were significantly lower in the FECD group (77.6±11.0) than in the control group (89.2±7.0) ( P =0.0006). All subscale scores were lower in the FECD group, particularly for distance vision and mental health (81.4±13.1 and 84.0±15.6, respectively) than in the control group (90.7±12.0 and 95.7±5.7) ( P =0.022 and P =0.0046, respectively). Corrected distance visual acuity in the dominant eye did not significantly correlate with composite scores or subscales in the FECD group.</p><p><strong>Conclusions: </strong>Quality of life is lower in patients with FECD than in healthy individuals, particularly regarding distance vision and mental health.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"e135-e141"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142814847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Piggyback Scleral Contact Lens to Enhance Cosmesis and Comfort in Uniocular Stevens-Johnson Syndrome.","authors":"Madhumathi Subramanian, Janani Balaji","doi":"10.1097/ICL.0000000000001143","DOIUrl":"10.1097/ICL.0000000000001143","url":null,"abstract":"<p><strong>Abstract: </strong>Stevens-Johnson syndrome often results in a significant reduction in vision, dryness, and photophobia based on severity. Scleral lenses are well-considered visual interventions that enhance vision and comfort, resulting in an increased quality of life for patients. This case report describes the enhancement of comfort, cosmesis, and reduction of photophobia using a piggyback system (scleral contact lenses over a prosthetic contact lens), whereas the other modalities were unsatisfactory.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"e157-e159"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142548723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact on Distance and Near Contrast Sensitivity of Multifocal Contact Lenses: A Systematic Review.","authors":"Kevin J Mena-Guevara, Dolores de Fez, David P Piñero","doi":"10.1097/ICL.0000000000001149","DOIUrl":"10.1097/ICL.0000000000001149","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the impact on distance and near contrast sensitivity (CS) after fitting multifocal contact lenses (MFCLs) for presbyopia correction according to the scientific evidence already published.</p><p><strong>Methods: </strong>Three bibliographic search was conducted on PubMed, Web of Sciences, and Scopus. Inclusion criteria were articles written in English evaluating distance and/or near CS in presbyopic patients using MFCLs, controlled clinical trials, and articles published from 2000 to 2024. After reading and analyzing carefully the articles that were finally included, the Critical Appraisal Skills Programme (CASP) tool for clinical trials was used to evaluate the quality of the research.</p><p><strong>Results: </strong>A total of eight articles were considered. One study did not find significant changes in binocular contrast sensitivity function (CSF) after fitting center-distance MFCL (CD) in the dominant eye and a center-near (CN) in the nondominant eye. Another research did not detect significant differences comparing CN MFCLs with monovision. However, another study found significant differences when comparing CN MFCL with spectacles. Half of studies only reported the comparison in CSF among different MFCL designs, with two studies confirming worse visual performance with MFCLs compared to pinhole contact lenses. Concerning the CASP analysis, some level of variability in the quality scores was found, with 5/13 in three studies, 6/13 in three studies, 7/13 in one study, and 8/13 in one study.</p><p><strong>Conclusions: </strong>The limited evidence on the impact on CS of using MFCLs does not allow to extract consistent generalizable conclusions, with only three studies suggesting a variable impact and no evidence of the real clinical benefit of using this metric for the evaluation and optimization of MFCL fitting. More research is needed on this topic.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"e117-e122"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Responses to Questions About Keratoconus Using ChatGPT-4.0, Google Gemini and Microsoft Copilot: A Comparative Study of Large Language Models on Keratoconus.","authors":"Suleyman Demir","doi":"10.1097/ICL.0000000000001158","DOIUrl":"10.1097/ICL.0000000000001158","url":null,"abstract":"<p><strong>Objectives: </strong>Large language models (LLMs) are increasingly being used today and are becoming increasingly important for providing accurate clinical information to patients and physicians. This study aimed to evaluate the effectiveness of generative pre-trained transforme-4.0 (ChatGPT-4.0), Google Gemini, and Microsoft Copilot LLMs in responding to patient questions regarding keratoconus.</p><p><strong>Methods: </strong>The LLMs' responses to the 25 most common questions about keratoconus asked by real-life patients were blindly rated by two ophthalmologists using a 5-point Likert scale. In addition, the DISCERN scale was used to evaluate the responses of the language models in terms of reliability, and the Flesch reading ease and Flesch-Kincaid grade level indices were used to determine readability.</p><p><strong>Results: </strong>ChatGPT-4.0 provided more detailed and accurate answers to patients' questions about keratoconus than Google Gemini and Microsoft Copilot, with 92% of the answers belonging to the \"agree\" or \"strongly agree\" categories. Significant differences were observed between all three LLMs on the Likert scale ( P <0.001).</p><p><strong>Conclusions: </strong>Although the answers of ChatGPT-4.0 to questions about keratoconus were more complex for patients than those of other language programs, the information provided was reliable and accurate.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"e107-e111"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11850007/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142774590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Review of Contact Lens Regulations in the Asia Pacific Region.","authors":"Jie Rong Jerome Lee, Ting Hui Yee, David Levitz, Blanche Xiao Hong Lim, Jodhbir Singh Mehta, Fiona Stapleton, Chris Hong Long Lim","doi":"10.1097/ICL.0000000000001150","DOIUrl":"10.1097/ICL.0000000000001150","url":null,"abstract":"<p><strong>Abstract: </strong>The increased usage of nonrefractive cosmetic contact lenses in Asia and a trend toward increased online purchasing of both refractive and cosmetic contact lenses poses unique challenges in the management of contact lens-related complications. However, regulations have lagged behind this increased uptake in the community. This paper reviews regulations surrounding the manufacturing, import, and distribution of contact lenses in the Asia Pacific region and compares them with international regulations from the European Union and United States. It found a need for more specific regulations and closer surveillance targeted at new trends in contact lens purchasing and usage. This paper also found a need for more effective enforcement of current regulations.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"e149-e156"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142789696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial Doctors: Performance of Chatbots as a Tool for Patient Education on Keratoconus.","authors":"Zeynep Özer Özcan, Levent Doğan, Ibrahim Edhem Yilmaz","doi":"10.1097/ICL.0000000000001160","DOIUrl":"10.1097/ICL.0000000000001160","url":null,"abstract":"<p><strong>Purpose: </strong>We aimed to compare the answers given by ChatGPT, Bard, and Copilot and that obtained from the American Academy of Ophthalmology (AAO) website to patient-written questions related to keratoconus in terms of accuracy, understandability, actionability, and readability to find out whether chatbots can be used in patient education.</p><p><strong>Methods: </strong>Twenty patient-written questions obtained from the AAO website related to keratoconus were asked to ChatGPT, Bard, and Copilot. Two ophthalmologists independently assessed the answers obtained from chatbots and the AAO website in terms of accuracy, understandability, and actionability according to the Structure of Observed Learning Outcome taxonomy, Patient Education Materials Assessment Tool-Understandability, and Patient Education Materials Assessment Tool-Actionability tests, respectively. The answers were also compared for readability according to the Flesch Reading Ease scores obtained through the website.</p><p><strong>Results: </strong>Bard had significantly higher scores compared with ChatGPT-3.5, Copilot, and AAO website according to Structure of Observed Learning Outcome taxonomy and Patient Education Materials Assessment Tool-Understandability ( P <0.001 for each), whereas there was no significant difference between the other groups. Bard and ChatGPT achieved significantly higher scores than the AAO website according to the Patient Education Materials Assessment Tool-Actionability scale ( P =0.001). The AAO website achieved significantly higher scores than the Bard on the Flesch Reading Ease scale, whereas there was no significant difference between the other groups ( P =0.017).</p><p><strong>Conclusion: </strong>Chatbots are promising to provide accurate, understandable, and actionable answers. Chatbots can be a valuable aid in the education of patients with keratoconus under clinician supervision. In this way, unnecessary hospital visits can be prevented, and the burden on the health care system can be alleviated, while patient awareness can be raised.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"e112-e116"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of Meibomian Gland Dysfunction by Classical Eyelid Hygiene Measures With and Without Additional Lipid Substitution for Tear Film Stabilization.","authors":"Isabel Weinstein, Augustin Kelava, Dieter Dausch, Berthold Seitz","doi":"10.1097/ICL.0000000000001155","DOIUrl":"10.1097/ICL.0000000000001155","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to document the treatment success of eyelid hygiene with liposomal suspension using new diagnostic tools and to determine whether additional lipid substitution provided measurable benefits in meibomian gland dysfunction.</p><p><strong>Methods: </strong>A single-center controlled, partially single masked study was conducted. Group A used eyelid hygiene only, whereas group B additionally applied a liposomal eye spray. Subjective perception using the Ocular Surface Disease Index (OSDI) questionnaire, measurement of tear film osmolarity, noninvasive tear film break-up time, assessment of the lipid layer, meibography, inspection of lid margins, assessment of the meibomian glands, and measurement of matrix-metallopeptidase-9 were collected at baseline and after 12 weeks.</p><p><strong>Results: </strong>Eighty-two patients were included and randomized into two groups. Both groups showed a decrease in OSDI score ( P <0.001), an increase in lipid layer thickness ( P <0.001), significant improvement in the degree of loss of meibomian glands ( P <0.001), in the damage pattern of the eyelid margins ( P <0.001), in the quality of meibomian gland secretion, and in matrix-metallopeptidase-9 after 12 weeks.</p><p><strong>Conclusions: </strong>Our study confirms the success of treatment with eyelid hygiene measures using a liposomal suspension. The additional benefit of lipid substitution was not significant after 12 weeks of treatment.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"e123-e128"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11850009/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142814866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors Contributing to Follow-up Nonadherence After Infectious Keratitis Diagnosis.","authors":"Pauline M Dmitriev, Shreya Swaminathan, Qiang Zhang, Christopher J Rapuano, Zeba A Syed","doi":"10.1097/ICL.0000000000001157","DOIUrl":"10.1097/ICL.0000000000001157","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate demographic, socioeconomic, and clinical factors associated with nonadherence with initial follow-up after a diagnosis of infectious keratitis.</p><p><strong>Methods: </strong>A retrospective chart review of patients aged 18 to 60 years who were diagnosed with infectious keratitis at the Wills Eye Hospital Emergency Room from March 2019 to September 2019 was conducted. The primary outcome was nonadherence with initial follow-up recommendation and included patients who did not follow-up in the time frame requested by the diagnosing physician and those who were lost to follow-up.</p><p><strong>Results: </strong>Two hundred and seventeen patients were included with a mean age of 39.0±11.6 years, and 38.2% of patients were nonadherent. Patients who identified as non-Hispanic White were more likely to be nonadherent compared with Hispanic White patients (odds ratio [OR]=5.00, 95% confidence interval [CI]: 1.27-20.00, P =0.021). Additional variables associated with nonadherence included lower income (OR=0.92, 95% CI: 0.85-0.99, P =0.020) and government versus private insurance (OR=2.13, 95% CI: 1.09-4.15, P =0.027). Among clinical variables, patients not cultured at the initial evaluation were more likely to be nonadherent (OR=2.54, 95% CI: 1.36-4.77, P =0.004).</p><p><strong>Conclusions: </strong>Race, income, insurance, and corneal culturing had associations with follow-up nonadherence. Identifying barriers to follow-up for infectious keratitis may have important implications in preventing vision loss and other complications.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"e129-e134"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142814846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Analysis of Cosmetic and Functional Outcomes in Corneal Tattooing (Keratopigmentation) versus Ocular Prosthesis.","authors":"Ebubekir Durmus, Omer Faruk Yilmaz, Zahide Büsra Sahin, Esma Ecem Ersoy Ozkan, Mehmet Serhat Mangan, Halit Oguz","doi":"10.1097/ICL.0000000000001162","DOIUrl":"10.1097/ICL.0000000000001162","url":null,"abstract":"<p><strong>Objectives: </strong>This study compares the cosmetic and functional outcomes of corneal tattooing/keratopigmentation and ocular prostheses in rehabilitating disfigured eyes, focusing on esthetic appearance and emotional well-being.</p><p><strong>Methods: </strong>Ninety-two patients were included: 48 received corneal tattooing, and 44 were fitted with ocular prostheses. Anophthalmic surgery was indicated for trauma, painful blind eye, endophthalmitis, tumor, and corneal ulcer, while corneal tattooing was performed for trauma, corneal ulcer, and endophthalmitis. Comprehensive ophthalmic examinations, a seven-item satisfaction questionnaire, and assessments of ocular movement in four directions and postoperative complications (e.g., infection, enophthalmos, fornix loss, and eyelid disorders) were conducted.</p><p><strong>Results: </strong>Patients who underwent ocular cosmetic rehabilitation reported high satisfaction, with corneal tattooing yielding higher satisfaction rates across all measures ( P <0.001). Patients with corneal tattooing exhibited significantly better ocular movement in all four cardinal directions ( P <0.001 for temporal, nasal, superior, and inferior). The prosthesis group experienced more postoperative complications, including ocular surface disorders and structural anomalies.</p><p><strong>Conclusion: </strong>Corneal tattooing and ocular prostheses both provide viable options for rehabilitating disfigured eyes. Corneal tattooing offers advantages in ocular movement, fewer complications, and higher patient satisfaction, while ocular prostheses are more suitable for addressing phthisis bulbi, tumors, and ocular pain.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"e142-e148"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Objective Analysis of the Effect of Obstructive Sleep Apnea on Anterior Segment Parameters.","authors":"Erdem Dursun, Baki Derhem, İsmet Karacan, Tevfik Oğurel","doi":"10.1097/ICL.0000000000001176","DOIUrl":"https://doi.org/10.1097/ICL.0000000000001176","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the effect of obstructive sleep apnea syndrome (OSAS) on corneal anterior segment parameters compared with body mass index (BMI)-matched and polysomnography (PSG)-negative healthy controls.</p><p><strong>Methods: </strong>This cross-sectional case-control study included 42 patients with OSAS and 25 age-sex BMI-matched and PSG-negative healthy volunteers. Obstructive sleep apnea syndrome was diagnosed by the polysomnographic sleep test, and the control subjects were determined from a negative overnight PSG. Maximum keratometry (Kmax), central corneal thickness, corneal symmetry index (SI), keratoconus vertex (KV), Baiocchi-Calossi-Versaci (BCV), anterior chamber volume (ACV), anterior chamber angle (ACA), and anterior chamber depth (ACD) values from topographic measurements and endothelial cell density (ECD), coefficient of variation, and hexagonality percentage (Hex) values from specular microscopic measurements were recorded.</p><p><strong>Results: </strong>In our study, 48 eyes of 24 patients with mild-moderate OSAS (Group 1) and 36 eyes of 18 patients with severe OSAS (Group 2) and 50 eyes of 25 BMI-matched and PSG-negative volunteers (Group 3) were evaluated. Among the keratoconus index values, front and back KV values were significantly higher in the OSAS group compared with the control group (P=0.001, P:0.003, respectively), while there was no significant difference in SI and BCV values (P>0.05). Central corneal thickness was statistically lower in the severe OSAS group compared with the control group. There was no statistically significant difference between patients with OSAS and controls in Kmax, ACD, ACA, and ACV values. Among the specular microscopic measurements, the ECD value was significantly lower in the severe OSAS group (P<0.05).</p><p><strong>Conclusion: </strong>In the study comparing age-sex and BMI-matched groups, some abnormal changes in corneal endothelial morphology and topographic keratoconus screening indices were observed in patients with OSAS. We assume that these corneal changes are due to intermittent hypoxia and hypoxia-induced inflammatory response during apnea-hypopnea episodes in OSAS.</p>","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143416135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}