Eye & Contact Lens-Science and Clinical Practice最新文献_第10页

Regional Variations in Corneal Epithelial Cell Density and Morphology Assessed Using In Vivo Confocal Microscopy. 利用体内共焦显微镜评估角膜上皮细胞密度和形态的区域性变化

IF 2.3 4区医学

Eye & Contact Lens-Science and Clinical Practice Pub Date : 2024-04-01 Epub Date: 2024-02-13 DOI: 10.1097/ICL.0000000000001067

Pradipta Bhattacharya, Katie Edwards, Katrina L Schmid

{"title":"Regional Variations in Corneal Epithelial Cell Density and Morphology Assessed Using In Vivo Confocal Microscopy.","authors":"Pradipta Bhattacharya, Katie Edwards, Katrina L Schmid","doi":"10.1097/ICL.0000000000001067","DOIUrl":"10.1097/ICL.0000000000001067","url":null,"abstract":"Aim: To characterize the regional variations in corneal epithelial cell density and morphology using in vivo confocal microscopy (IVCM).Methods: Corneal imaging (IVCM) at 10 locations was performed; corneal apex (i.e., the center), immediately anterior to the corneal nerve whorl (i.e., slightly inferior to the apex), and four quadrants (superior, nasal, inferior, and temporal) both at 1.5 mm and 4.5 mm from the corneal apex (corresponding to 3 mm central and 9 mm peripheral diameter rings). The data of 21 young adults, aged 18 to 35 years, were analyzed. Cell morphometric parameters, including cell density, area, perimeter, Feret diameter, and circularity, were measured for basal and wing cells using Image J software.Results: There was a significant difference in basal cell density (BCD) ( P <0.001) and wing cell density (WCD) ( P <0.001) for different corneal locations. The BCD (mean±SD: 8,839±416 cells/mm 2 ) and WCD (mean±SD: 5,932±310 cells/mm 2 ) were highest at the corneal nerve whorl compared with all other corneal locations. There were significant differences in wing cell area ( P <0.001), perimeter ( P <0.001), Feret diameter ( P <0.001), and circularity ( P <0.001) at varying corneal locations.Conclusion: There are significant regional variations in corneal epithelial cell density and morphology. The BCD and WCD was highest anterior to the corneal nerve whorl.","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"163-170"},"PeriodicalIF":2.3,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139730905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Accelerated Corneal Crosslinking to Arrest Progression of Corneal Ectasia: A Prospective Multicenter Study. 加速角膜交联以阻止角膜异位症恶化：一项前瞻性多中心研究。

IF 2.3 4区医学

Eye & Contact Lens-Science and Clinical Practice Pub Date : 2024-03-01 Epub Date: 2024-02-07 DOI: 10.1097/ICL.0000000000001065

Borja Salvador-Culla, Ahmmed Afsara, Nicola Roper, Julie Mulroy, Lubomira Galankova, Holly Duncan, David Tabibian, Jose Lamarca-Mateu, Francisco C Figueiredo

{"title":"Accelerated Corneal Crosslinking to Arrest Progression of Corneal Ectasia: A Prospective Multicenter Study.","authors":"Borja Salvador-Culla, Ahmmed Afsara, Nicola Roper, Julie Mulroy, Lubomira Galankova, Holly Duncan, David Tabibian, Jose Lamarca-Mateu, Francisco C Figueiredo","doi":"10.1097/ICL.0000000000001065","DOIUrl":"10.1097/ICL.0000000000001065","url":null,"abstract":"Objectives: To report the results of epithelium-off accelerated corneal collagen crosslinking (accelerated corneal crosslinking [ACXL]) in patients with progressive keratoconus.Methods: This prospective, nonrandomized, noncomparative, interventional, multicenter clinical study included all patients who underwent ACXL, either continuous (c-ACXL; 9 mW/cm 2 , 10', 5.4 J/cm 2 ) or pulsed (p-ACXL; 2″ON/1″OFF, 30 mW/cm 2 , 4.5', 5.4 J/cm 2 ) between January 2014 and May 2017. Best-corrected visual acuity, sphere, cylinder, spherical equivalent, and topographical keratometry data were collected preoperatively and at 1, 3, 6, 12, 18, and 24 months postoperatively.Results: Ninety-six eyes of 78 patients were included. The mean age was 20.8±4.4 years (14-33) for c-ACXL and 26.7±7.7 years (12-37) for p-ACXL. The mean best-corrected visual acuity was 0.4±0.4 for c-ACXL and 0.01±0.1 for p-ACXL preoperatively, and 0.3±0.3 ( P =0.0014) and -0.01±0.1 ( P =0.1554), respectively, at the last follow-up. The subjective sphere and spherical equivalent did not show statistically significant differences between the time points ( P >0.05). The subjective cylinder showed significant differences ( P =0.0013 for c-ACXL; P =0.0358 for p-ACXL). Keratometric values (K steep , K flat , and SimK) remained stable, with no statistically significant differences ( P >0.05). No major complications were noted.Conclusions: Both c-ACXL and p-ACXL are equally safe and effective ACXL protocols in stabilizing the progression of keratoconus and can be considered alternatives to the conventional Dresden protocol.","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"126-131"},"PeriodicalIF":2.3,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139724838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sleep Quality in Patients With Ocular Graft-Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation. 异基因造血干细胞移植后眼部移植物抗宿主病患者的睡眠质量。

IF 2.3 4区医学

Eye & Contact Lens-Science and Clinical Practice Pub Date : 2024-03-01 Epub Date: 2023-10-04 DOI: 10.1097/ICL.0000000000001039

Yinglin Liao, Jing Li, Jing Yang, Wenxin Zhao, Ziyan Chen, Shaowen Wu, Ling Jin, Fen Huang, Lingyi Liang

{"title":"Sleep Quality in Patients With Ocular Graft-Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation.","authors":"Yinglin Liao, Jing Li, Jing Yang, Wenxin Zhao, Ziyan Chen, Shaowen Wu, Ling Jin, Fen Huang, Lingyi Liang","doi":"10.1097/ICL.0000000000001039","DOIUrl":"10.1097/ICL.0000000000001039","url":null,"abstract":"Objectives: To investigate the sleep quality in patients with ocular graft-versus-host disease (oGVHD) compared with patients without oGVHD after allogeneic hematopoietic stem cell transplantation (alloHCT) and healthy controls.Methods: This cross-sectional study analyzed 142 patients after alloHCT including 94 patients with oGVHD and 48 without. Fifty healthy controls were also enrolled. oGVHD was diagnosed according to International Chronic Ocular GVHD Consensus Group (ICOGCG) criteria. Sleep quality was assessed by the Chinese version of the Pittsburgh Sleep Quality Index (CPSQI). Poor sleep quality was defined as CPQSI score greater than 6.Results: Patients after alloHCT demonstrated a significantly higher CPQSI score than those of controls {7.0 [interquartile range (IQR) 5.0-10.0] vs. 5.5 [IQR 4.8-7.0], P =0.002}, especially in the oGVHD subgroup (7.5 [IQR 5.0-11.0] vs. 6.0 [IQR 5.0-8.0], P =0.04) with nearly double prevalence of poor sleep quality (58 [62%] vs. 18 [37%], P =0.006). Poor sleep quality was strikingly correlated with oGVHD diagnosis (adjusted odds ratio [OR]=2.55, 95% confidence interval [CI]: 1.02-6.34, P =0.04) and systemic immunosuppressants (adjusted OR=2.61, 95% CI: 1.32-5.71, P =0.02). Among the ocular parameters, poor sleep quality was significantly associated with higher ICOGCG score (adjusted OR=1.20, 95% CI: 1.03-1.39, P =0.02) and lower tear film break-up time (adjusted OR=0.85, 95% CI: 0.74-0.99, P =0.05).Conclusions: Poor sleep quality was associated with an increased severity of oGVHD and tear film instability in the long-term alloHCT survivorship.","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"145-151"},"PeriodicalIF":2.3,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41174698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Corneal Tomography in a Commercially Available Optical Coherence Tomography Device and Comparison With a Rotating Scheimpflug Camera. 市售光学相干断层扫描设备的角膜断层成像以及与旋转式 Scheimpflug 相机的比较。

IF 2.3 4区医学

Eye & Contact Lens-Science and Clinical Practice Pub Date : 2024-03-01 Epub Date: 2024-01-04 DOI: 10.1097/ICL.0000000000001063

Piotr Kanclerz, Szymon Adam Radomski

{"title":"Corneal Tomography in a Commercially Available Optical Coherence Tomography Device and Comparison With a Rotating Scheimpflug Camera.","authors":"Piotr Kanclerz, Szymon Adam Radomski","doi":"10.1097/ICL.0000000000001063","DOIUrl":"10.1097/ICL.0000000000001063","url":null,"abstract":"Objective: To compare the outcomes of corneal tomography obtained with an anterior-to-posterior segment optical coherence tomography device (Revo, Optopol Technologies Sp. z o.o.) and a rotating Scheimpflug camera (Pentacam AXL, Oculus Optikgeräte, Wetzlar, Germany).Methods: In healthy subjects, agreement in stereometric parameters commonly used in cataract and refractive surgery was assessed. Comparison between the devices was performed using correlation coefficients, the Bland-Altman method, and a paired t test.Results: Results of right eyes of 78 patients (47 women) aged 25.24±5.56 years were analyzed. The flat and steep anterior keratometry values were significantly higher for Revo than Pentacam (43.65±1.58 D vs. 42.99±1.47 D; P = 0.000, and 44.53±1.57 D vs. 43.82±1.49 D; P =0.000, respectively) and showed excellent correlation ( r =0.978 and 0.974, respectively). The results for maximal keratometry manifested a higher difference (45.89±1.69 D vs. 44.27±1.51 D for Revo and Pentacam, P =0.000) but were also strongly correlated ( r =0.871). Revo showed significantly lower corneal thickness values than Pentacam, both for apex pachymetry (535.54±32.45 vs. 550.74±31.55 μm; P =0.000) and for thinnest pachymetry (522.58±32.16 vs. 547.25±31.95 μm; P =0.000). The correlation coefficients for anterior and posterior corneal elevation at the thinnest point showed weak positive correlation ( r =0.179 and 0.185), while the correlation for corneal asphericity was moderate ( r =0.317).Conclusions: There was a significant difference between keratometric values obtained with Revo and the Pentacam AXL, although the measurements showed excellent correlation. Similar results were found for corneal thickness measurements, but not for corneal surface elevation and corneal asphericity.","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"138-144"},"PeriodicalIF":2.3,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139106879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Double-Blind Comparison of Eyelash Epilation Techniques for the Purpose of Demodex folliculorum Mite Retrieval. 以毛囊线虫螨虫检索为目的的睫毛脱毛技术的双盲比较。

IF 2.3 4区医学

Eye & Contact Lens-Science and Clinical Practice Pub Date : 2024-03-01 Epub Date: 2024-02-06 DOI: 10.1097/ICL.0000000000001070

Etty Bitton, Walter Wittich

{"title":"Double-Blind Comparison of Eyelash Epilation Techniques for the Purpose of Demodex folliculorum Mite Retrieval.","authors":"Etty Bitton, Walter Wittich","doi":"10.1097/ICL.0000000000001070","DOIUrl":"10.1097/ICL.0000000000001070","url":null,"abstract":"Objective: Demodex folliculorum blepharitis is typically confirmed with lash epilation and microscopic identification of mites. However, mite counts may vary with the epilation technique. As there is no gold standard to epilating lashes for the purposes of mite counts, the aim of this study was to compare three epilation techniques.Method: A prospective randomized double-blind study compared three epilation techniques on lashes with cylindrical dandruff. Techniques included (A) direct pulling of the lash; (B) rotating the lash before epilation; and (C) sliding the cylindrical dandruff away, lash rotation, and epilation. Mean mite counts were analyzed using a repeated-measures analysis of variance.Results: Forty (n=40) participants (20 M: 20 F, mean age of 62.3±17.1 years) revealed similar mite counts between right (1.43±1.74) and left (1.35±1.59) eyes ( P =0.63). A significant difference ( P =0.03) in mite count was noted (technique A: 1.05 ± 1.60; technique B 1.76 ± 1.80; and technique C 1.36 ± 1.54) with technique B yielding the highest mite count ( P =0.04).Conclusion: Demodex mite count is a key parameter in establishing infestation or to determine treatment efficacy. This study revealed that rotating the lash before epilation yielded the highest mite count. Future studies should report the epilation technique used to allow for study comparisons.","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"152-157"},"PeriodicalIF":2.3,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139724839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of Keratoconus Among High School Students in Southern Brazil: A Community-Based Study. 巴西南部高中生角膜炎患病率：一项基于社区的研究。

IF 2.3 4区医学

Eye & Contact Lens-Science and Clinical Practice Pub Date : 2024-03-01 Epub Date: 2024-02-07 DOI: 10.1097/ICL.0000000000001066

Otavio de Azevedo Magalhães, Bruna Nunes Pagano, Luana Veber Grellmann, Victor Sanchez Zago, Claudia Leite Kronbauer

{"title":"Prevalence of Keratoconus Among High School Students in Southern Brazil: A Community-Based Study.","authors":"Otavio de Azevedo Magalhães, Bruna Nunes Pagano, Luana Veber Grellmann, Victor Sanchez Zago, Claudia Leite Kronbauer","doi":"10.1097/ICL.0000000000001066","DOIUrl":"10.1097/ICL.0000000000001066","url":null,"abstract":"Objectives: This study aimed to determine the prevalence of keratoconus (KC) in teenagers who live in Southern Brazil and detect any possible associated factors.Methods: This prospective, observational, mobile clinic-based cross-sectional study collected data from students between 14 and 21 years from seven high schools who were living in the Greater Porto Alegre metropolitan region in Southern Brazil. Subjects were clinically surveyed and examined using a slitlamp and rotational Scheimpflug corneal tomography system. All data were collected at the mobile clinic during a single visit.Results: Eight-hundred twenty-six students were evaluated (357 boys and 469 girls) with an average age of 16.7±1.2 years. Six subjects were classified as having KC (four girls), yielding a prevalence rate of 0.73% (95% confidence interval, 0.27%-1.57%) or one per 137 teenagers in Southern Brazil. Logistic regression showed an association between KC and positive history of eye rubbing ( P =0.02).Conclusion: According to our investigation, this is the first KC prevalence study in South America using the latest technologies (Scheimpflug imaging). The prevalence of KC among teenagers in Southern Brazil is within the highest reported worldwide. We also found an association between KC and history of eye rubbing. Keratoconus is not an uncommon disorder in our population, and the efforts to identify the disease and reduce its risk factors in an earlier phase are justified.","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"117-120"},"PeriodicalIF":2.3,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139724841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of Keratoconus Based on Scheimpflug Corneal Tomography Metrics in a Pediatric Population From a Chicago-Based School Age Vision Clinic. 基于 Scheimpflug 角膜断层扫描指标的芝加哥学龄儿童视力诊所小儿角膜炎患病率。

IF 2.3 4区医学

Eye & Contact Lens-Science and Clinical Practice Pub Date : 2024-03-01 Epub Date: 2024-02-07 DOI: 10.1097/ICL.0000000000001072

Jennifer S Harthan, John D Gelles, Sandra S Block, William Tullo, Andrew S Morgenstern, Becky Su, Daniel Chung, Austin Yu, Steven A Greenstein, Peter S Hersh, Steven Barry Eiden

{"title":"Prevalence of Keratoconus Based on Scheimpflug Corneal Tomography Metrics in a Pediatric Population From a Chicago-Based School Age Vision Clinic.","authors":"Jennifer S Harthan, John D Gelles, Sandra S Block, William Tullo, Andrew S Morgenstern, Becky Su, Daniel Chung, Austin Yu, Steven A Greenstein, Peter S Hersh, Steven Barry Eiden","doi":"10.1097/ICL.0000000000001072","DOIUrl":"10.1097/ICL.0000000000001072","url":null,"abstract":"Purpose: Determine the pediatric prevalence of keratoconus (KC) using Scheimpflug corneal tomography.Methods: A prospective observational study was done on subjects aged 3 to 18 years at the Princeton Vision Clinic, Chicago, IL. Scheimpflug tomography (Pentacam HR, OCULUS Optikgerate GmbH) scans (Belin/Ambrósio Enhanced Ectasia BAD3) yielded BAD Final D (Final D) and Back Elevation at the Thinnest Point (BETP) measurements. Criteria differentiating non-KC from KC suspects & KC were, Non-KC -Final D <2.00 in both eyes; KC suspect -Final D ≥2.00 and <3.00 in combination with BETP ≥18 μm for myopia and ≥28 μm for hyperopia/mixed astigmatism in at least one eye; and KC -Final D of ≥3.00 with BETP ≥18 μm for myopia or ≥28 μm for hyperopia/mixed astigmatism in at least one eye. Two thousand two hundred and six subjects were recorded, removing duplicate and poor-quality scans leaving 2007 subjects.Results: Of 2007 subjects, six were classified as KC -prevalence of 1:334, three subjects were KC suspects -prevalence of 1:669, and total prevalence of KC suspects and KC was 1:223.Conclusion: The prevalence of KC in children is higher than previously reported, emphasizing the importance of sensitive screening for KC at its earliest manifestation as standard in pediatric comprehensive eye examinations.","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"121-125"},"PeriodicalIF":2.3,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139724842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Autologous Serum and Platelet-Rich Plasma on Human Corneal Endothelial Cell Regeneration: A Comparative Study. 自体血清和富血小板血浆对人角膜内皮细胞再生影响的比较研究。

IF 2.3 4区医学

Eye & Contact Lens-Science and Clinical Practice Pub Date : 2024-02-01 Epub Date: 2023-11-29 DOI: 10.1097/ICL.0000000000001056

Emine Kilic-Toprak, Aysegul Cort-Donmez, Ibrahim Toprak

{"title":"Effects of Autologous Serum and Platelet-Rich Plasma on Human Corneal Endothelial Cell Regeneration: A Comparative Study.","authors":"Emine Kilic-Toprak, Aysegul Cort-Donmez, Ibrahim Toprak","doi":"10.1097/ICL.0000000000001056","DOIUrl":"10.1097/ICL.0000000000001056","url":null,"abstract":"Objectives: To investigate the effects of autologous serum (AS) and platelet-rich plasma (PRP) on human corneal endothelial cell (HCEC) proliferation and apoptosis in comparison to Y-27632 as the commonly studied Rho-associated kinase (ROCK) inhibitor.Methods: The human corneal endothelial primary cell line was used for this study. As the treatment groups, HCECs were incubated with AS, PRP, and Y-27632, whereas the control group received no treatment. Cell proliferation (measured by 5-bromo-2'-deoxyuridine [BrdU] incorporation) and apoptosis (based on the caspase-3 level) were compared between the control, Y-27632, AS, and PRP groups.Results: In the Y-27632, AS, and PRP groups, the ratios of BrdU-incorporated cells were significantly higher (115±0.2%, 125±0.2%, 122±0.4% at 24 hr, and 138±2.4%, 160±0.2%, 142±0.2% at 48 hr, respectively) than in the control group (100±18.4% at 24 hr, 100±1.1% at 48 hr) ( P <0.05 for all). Furthermore, AS provided a higher HCEC proliferation ratio compared with the Y-27632 group at 24 and 48 hr ( P <0.05 for all). Caspase-3 was significantly lower in the AS group (60.3±3.3%) than in the control (100±2.3%), Y-27632 (101.9±5.2%), and PRP (101±6.8%) groups ( P <0.05 for all).Conclusions: The results of this study demonstrated for the first time that AS and PRP promoted HCEC proliferation and AS significantly decreased apoptosis in HCECs. A superior effect on HCEC proliferation was also observed with AS compared with Y-27632. Future \"autologous\" regenerative therapeutic options for corneal endothelial failure may involve the utilization of AS and PRP owing to their accessibility, simplicity in preparation, immunologic compatibility, and donor-free nature.","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"106-111"},"PeriodicalIF":2.3,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138452922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Patient Experiences With Therapeutic Contact Lenses and Dry Eye Disease. 患者使用治疗性隐形眼镜和干眼症的经验。

IF 2 4区医学

Eye & Contact Lens-Science and Clinical Practice Pub Date : 2024-02-01 Epub Date: 2023-11-01 DOI: 10.1097/ICL.0000000000001051

Ellen Shorter, Cherie B Nau, Jennifer S Fogt, Amy Nau, Muriel Schornack, Jennifer Harthan

{"title":"Patient Experiences With Therapeutic Contact Lenses and Dry Eye Disease.","authors":"Ellen Shorter, Cherie B Nau, Jennifer S Fogt, Amy Nau, Muriel Schornack, Jennifer Harthan","doi":"10.1097/ICL.0000000000001051","DOIUrl":"10.1097/ICL.0000000000001051","url":null,"abstract":"Objectives: To report patient-reported experiences with dry eye disease and therapeutic contact lenses.Methods: A survey was distributed to patients with dry eye disease. Demographics, Ocular Surface Disease Index (OSDI), systemic disease, contact lens history, and burden of care information were collected. Descriptive statistics are presented and categorized by nonlens, soft lens, and scleral lens (SL) wearers.Results: Of 639 respondents, 15% (94/639) were currently using therapeutic soft or SLs (47 soft and 69 SL). Mid-day fogging or clouding of vision was reported by SL (75%, 50/67) and soft lens (62%, 29/47) wearers. Seventy-two percent of SL wearers spent more than 20 min daily on dry eye treatment while 43% of soft lens wearers spent more than 20 min. Median annual expenditure was higher for SL ($1,500, n=63) than nonlens ($500, n=371) or soft lens wearers ($700, n=43). Mean OSDI scores in all groups were in the severe category (51±22 years, n=401 nonlens wearers; mean age; 45±22 years, n=47 soft lens wearers; 60±24 years, n=69 SL wearers).Conclusions: Mid-day fogging and blurring of vision was reported by most of the individuals using therapeutic lenses for dry eye disease. SL wearers allocate the most resources for dry eye care.","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"59-64"},"PeriodicalIF":2.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10843105/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71428659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Inflammatory and Cytological Effect of Repeated Povidone-Iodine Application in Patients Receiving Intravitreal Injections. 玻璃体内注射患者反复应用聚维酮碘对炎症和细胞学的影响。

IF 2.3 4区医学

Eye & Contact Lens-Science and Clinical Practice Pub Date : 2024-02-01 Epub Date: 2023-10-04 DOI: 10.1097/ICL.0000000000001044

Ersin Akbulut, Furkan Kirik, Cansu Ekinci Aslanoglu, Emine Rümeysa Hekimoglu, Ebru Haciosmanoglu Aldogan, Mehmet Hakan Ozdemir

{"title":"The Inflammatory and Cytological Effect of Repeated Povidone-Iodine Application in Patients Receiving Intravitreal Injections.","authors":"Ersin Akbulut, Furkan Kirik, Cansu Ekinci Aslanoglu, Emine Rümeysa Hekimoglu, Ebru Haciosmanoglu Aldogan, Mehmet Hakan Ozdemir","doi":"10.1097/ICL.0000000000001044","DOIUrl":"10.1097/ICL.0000000000001044","url":null,"abstract":"Objective: To investigate the effect of repeated povidone-iodine (PVI) application on the ocular surface parameters of patients who received intravitreal injections.Materials and methods: In this prospective study, 52 eyes of 52 patients with age-related macular degeneration who underwent unilateral intravitreal injection at least three times in the last 1 year (intravitreal injection [IVI] group), 52 fellow eyes with no previous intravitreal injection (NIVI group), and 51 eyes of 51 healthy subjects (control) were included. Tear break-up time (TBUT), the Schirmer test, the Oxford staining score, the Ocular Surface Disease Index questionnaire, conjunctival impression cytology, and tear inflammatory cytokine levels (interleukin [IL]-1β and IL-6) were analyzed in all participants.Results: The IVI group had lower TBUT and higher Oxford staining score than the NIVI and control groups ( P <0.05). No significant difference was found between the groups in the Schirmer test ( P =0.161). Conjunctival impression cytology analysis revealed that the IVI group had a significantly lower goblet cell count and significantly higher Nelson staging result than the NIVI and control groups ( P <0.05). As a result of tear cytokine analysis, although IVI and NIVI groups had higher IL-1β and IL-6 levels than the control group ( P <0.05), there was no difference between NIVI and IVI groups ( P ≥0.05).Conclusions: Repeated PVI application caused cytotoxic injury to the ocular surface, resulting in goblet cell loss and squamous metaplasia of epithelial cells. As a result, the stability of the tear film layer was found to be impaired and ocular surface-related symptoms developed in patients.","PeriodicalId":50457,"journal":{"name":"Eye & Contact Lens-Science and Clinical Practice","volume":" ","pages":"73-78"},"PeriodicalIF":2.3,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41146410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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