l-Cysteine Graphene Oxide Deposition on Contact Lenses.

IF 2.1 4区医学 Q2 OPHTHALMOLOGY

Eye & Contact Lens-Science and Clinical Practice Pub Date : 2025-10-13 DOI:10.1097/ICL.0000000000001230

Krupa Mukkaragari, Pratap Kollu, Nagaraju Konda

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引用次数: 0

Abstract

Objective: l-cysteine graphene oxide (CysGO) was synthesized and deposited onto the hydrogel and silicone hydrogel contact lenses (CLs) to study the surface characterization.

Methods: A cysteine graphene oxide composite was synthesized, characterized, and deposited on commercially available soft CLs. Characterization techniques such as FESEM, Fourier Transform Infrared, Raman spectroscopy, X-ray photoelectron spectroscopy (XPS), and Ultraviolet-Visible spectroscopy were employed to analyze CysGO deposited lens surface characterisation. Swelling and transmission percentages were calculated.

Results: Raman spectra revealed an increased Id/Ig ratio of 2.5 for CysGO compared with GO (2.25), indicating reduced layer stacking due to cysteine interaction. IR spectra confirmed the presence of amide groups, and XPS spectra exhibited a distinct s2p peak at 164eV and N2 spectrum at 399 eV exclusively in CysGO, confirming its deposition on the lens substrate. The deposited CLs showed a uniform coating of CysGO, an increase in the swelling percentage (P<0.001), and no difference in transmittance percentage when compared with the control.

Conclusion: This study presents the inaugural investigation of CysGO deposition applied to CL, revealing its advantageous properties, including uniformity and enhanced wettability. The potential of this coating extends beyond these characteristics, prompting further exploration of its diverse properties and applications in subsequent studies.

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隐形眼镜上的l-半胱氨酸氧化石墨烯沉积。

目的：合成l-半胱氨酸氧化石墨烯（CysGO），并将其沉积在水凝胶和硅酮水凝胶隐形眼镜（CLs）上，研究其表面表征。方法：合成半胱氨酸氧化石墨烯复合材料，对其进行表征，并将其沉积在市售的软CLs上。采用FESEM、傅里叶变换红外、拉曼光谱、x射线光电子能谱（XPS）和紫外可见光谱等表征技术分析了CysGO沉积透镜的表面特征。计算肿胀率和透射率。结果：拉曼光谱显示，与氧化石墨烯（2.25）相比，CysGO的Id/Ig比增加了2.5，表明半胱氨酸相互作用减少了层堆积。红外光谱证实了CysGO中酰胺基团的存在，XPS光谱在164eV处显示出明显的s2p峰，在399 eV处显示出N2峰，证实了CysGO沉积在透镜衬底上。结论：本研究首次研究了CysGO沉积在CL上的应用，揭示了其优越的性能，包括均匀性和增强的润湿性。这种涂层的潜力超出了这些特性，促使其在后续研究中进一步探索其不同的性能和应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Eye & Contact Lens-Science and Clinical Practice OPHTHALMOLOGY-

CiteScore

4.50

自引率

4.30%

发文量

150

审稿时长

6-12 weeks

期刊介绍： Eye & Contact Lens: Science and Clinical Practice is the official journal of the Contact Lens Association of Ophthalmologists (CLAO), an international educational association for anterior segment research and clinical practice of interest to ophthalmologists, optometrists, and other vision care providers and researchers. Focusing especially on contact lenses, it also covers dry eye disease, MGD, infections, toxicity of drops and contact lens care solutions, topography, cornea surgery and post-operative care, optics, refractive surgery and corneal stability (eg, UV cross-linking). Peer-reviewed and published six times annually, it is a highly respected scientific journal in its field.