Indian Journal of Dermatology Venereology & Leprology最新文献

{"title":"Association between high-risk human papillomavirus and cervico-vaginal infections in tribal women screened for cervical precancers and cancers in Maharashtra, India: A cross-sectional study.","authors":"Kiran Munne, Shantanu Birje, Anushree Patil, Anamika Akula, Anjali Mayekar, Ganga Bhekare, Sayantika Kumari, Sonu Babu, Leena Tendulkar, Shilpa Kerkar, Prerana Patil, Deepti Tandon, Saleem Pathuthara, Kedar Deodhar, Sanjay Biswas, Shahina Begum, Jayanti Mania Pramanik, Sharmila Pimple, Beena Joshi, Neha Salvi, Sanjay Chauhan","doi":"10.25259/IJDVL_1501_2024","DOIUrl":"https://doi.org/10.25259/IJDVL_1501_2024","url":null,"abstract":"<p><p>Background The vaginal microenvironment is thought to impact infection and persistence of the human papillomavirus which is a necessity for cervical carcinogenesis. Tribal women are at risk for human papillomavirus and cervicovaginal infections due to polygamy, poor hygiene, and illiteracy. Aims We evaluated the association of common cervico-vaginal infections with human papillomavirus infection and cervical precancers among the tribal women of Dahanu taluka, Maharashtra, India. Methods For this cross-sectional study, tribal women from Dahanu taluka were recruited. Cervical brushing samples were collected from them and tested for human papillomavirus by the Hybrid Capture 2 method and polymerase chain reaction for Chlamydia trachomatis. Vaginal samples were collected for gram staining and examined for candidiasis and bacterial vaginosis, followed by visual inspection of the cervix with acetic acid. Results A total of 501 sexually active tribal women were recruited, among whom the human papillomavirus infection rate was 6.5%. Evaluation of vaginal smears by Nugent's scoring revealed bacterial vaginosis in 208 (41.5%), candidiasis in 30 (5.98%), and chlamydia in five (1%) participants. Bacterial vaginosis prevalence was higher in high-risk human papillomavirus-positive women. The presence of clue cells was associated with human papillomavirus positivity, suggesting an association between bacterial vaginosis and human papillomavirus infection and indicating an increased risk of human papillomavirus infection on co-infection with bacterial vaginosis. Limitations Only tribal women were screened, with no screening for other sexually transmitted infections. Since participants were recruited from healthcare centres instead of random sampling, this may have affected infection rate estimates. Due to regional differences in sexual behaviours and gynaecological morbidities, our findings cannot be generalised to tribal women from other regions. Conclusion Early detection and management of reproductive tract and sexually transmitted infections is paramount for preventing co-infections and reduces the risk of cervical carcinogenesis.</p>","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-9"},"PeriodicalIF":3.2,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genotype-phenotype spectrum and correlations in Chinese patients with keratinocytic epidermal naevus: A retrospective study of 22 cases.","authors":"Zhongtao Li, Sheng Wang","doi":"10.25259/IJDVL_1292_2024","DOIUrl":"https://doi.org/10.25259/IJDVL_1292_2024","url":null,"abstract":"<p><p>Background Keratinocytic epidermal naevus is characterised by hyperkeratotic lesions arranged along Blaschko's lines. So far, multiple genes have been implicated, but there is no detailed data or genotype-phenotype correlation studies of keratinocytic epidermal naevi in Chinese patients. Objective To evaluate the clinical, histopathological and genetic features, genotype-phenotype correlations of keratinocytic epidermal naevus in the Chinese population. Methods A retrospective study of patients with keratinocytic epidermal naevi referred to the Department of Dermatology, West China Hospital, in the last four years. Medical history, clinical data, histopathological characteristics, and evidence of genetic mutations were collected from 22 unrelated Chinese patients with this problem. Results The distribution of the keratinocytic epidermal naevi exhibited right-side dominance. Non-epidermolytic epidermis naevus was much more common. Eight reported missense mutations were found in this study, which were detected in five genes, including HRAS, KRT10, FGFR3, GJB2, and PIK3CA. HRAS was the most commonly affected gene (9/22, 40.91%) in this study, with the c.37G>C (6/22, 27.27%) substitution representing a possible hotspot mutation. Mutation allele loads were higher in the affected lesions than blood samples. Epidermolytic epidermal naevus was found in three patients exclusively carrying KRT10 mutations. Inflammatory epidermal naevi were caused by mutations of KRT10 and PIK3CA. Most of the mosaic mutations detected in keratinocytic epidermal naevi patients were the same as germline mutations identified in systemic diseases caused by these genes. Limitations The retrospective nature of the study. Conclusion Our findings reveal the genotype-phenotype spectrum and their correlation amongst Chinese patients with keratinocytic epidermal naevi. In addition, our data underscores the importance of genetic testing in lesional skin to help characterise and categorise keratinocytic epidermal naevi, decide on a therapeutic strategy, and offer genetic counselling and prenatal diagnosis.</p>","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-6"},"PeriodicalIF":3.2,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Newer entities in dermatology: A short review on the newly defined dermatoses and acronyms.","authors":"Sukhdeep Singh, Manavi Gupta, Anuradha Bishnoi, Sanjeev Handa","doi":"10.25259/IJDVL_710_2024","DOIUrl":"https://doi.org/10.25259/IJDVL_710_2024","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-5"},"PeriodicalIF":3.2,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corymbiform syphilis: A remarkable presentation with several coexistent morphologies.","authors":"Bryce McKenzie DeLong, Subuhi Kaul, David Othman, Shilpa Mehta","doi":"10.25259/IJDVL_1874_2024","DOIUrl":"https://doi.org/10.25259/IJDVL_1874_2024","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1"},"PeriodicalIF":3.2,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mutation analysis in three Chinese pedigrees with palmoplantar keratoderma caused by SERPINB7 gene mutations.","authors":"Hongmin Han, Jing Li, Yaqi Cao, Chunyu Han, Xin Li, Yi Zhang, Jianwen Han","doi":"10.25259/IJDVL_1062_2024","DOIUrl":"https://doi.org/10.25259/IJDVL_1062_2024","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-3"},"PeriodicalIF":3.2,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between final diagnosis and the levels of lactate dehydrogenase/soluble interleukin-2 receptor in the random skin biopsy-performed patients: A retrospective study of 50 cases.","authors":"Hiroshi Miida","doi":"10.25259/IJDVL_1321_2024","DOIUrl":"https://doi.org/10.25259/IJDVL_1321_2024","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-3"},"PeriodicalIF":3.2,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cutaneous metastases from ovarian clear cell carcinoma.","authors":"Teng Liu, Jianmin Chang","doi":"10.25259/IJDVL_1886_2024","DOIUrl":"https://doi.org/10.25259/IJDVL_1886_2024","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1"},"PeriodicalIF":3.2,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143257095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case of eyelid capillary telangiectasia in juvenile clinically amyopathic dermatomyositis.","authors":"Shreya K Gowda, Biswanath Behera, Bhini Ameta, Bevan Priyadharsan, Ranjan Kumar Patel","doi":"10.25259/IJDVL_1407_2024","DOIUrl":"https://doi.org/10.25259/IJDVL_1407_2024","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-3"},"PeriodicalIF":3.2,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143256940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Crusted scabies in an atopic dermatitis patient on treatment with dupilumab.","authors":"Veronica Hamann Aita, Daniel Lorenzini, Gabriela Agne Magnus, Magda Blessmann Weber","doi":"10.25259/IJDVL_753_2024","DOIUrl":"https://doi.org/10.25259/IJDVL_753_2024","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-2"},"PeriodicalIF":3.2,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143257093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eccrine syringofibroadenoma and amyloidosis cutis dyschromica: A new association.","authors":"Mona Mostafa Korany, Yousra Azzazi, Asmaa Sobhy Amer, Salma Maged Abdelraouf, Marwa Mohamed Fawzy, Mohammad El-Darouti","doi":"10.25259/IJDVL_1423_2024","DOIUrl":"https://doi.org/10.25259/IJDVL_1423_2024","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-3"},"PeriodicalIF":3.2,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143257097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}