Akash Deep Chandra, Sujay Khandpur, M Ramam, Neetu Bhari, Vishal Gupta, Shipra Agarwal
{"title":"Clinico-histopathological review of cutaneous sarcoidosis: A retrospective descriptive study.","authors":"Akash Deep Chandra, Sujay Khandpur, M Ramam, Neetu Bhari, Vishal Gupta, Shipra Agarwal","doi":"10.25259/IJDVL_368_2024","DOIUrl":"10.25259/IJDVL_368_2024","url":null,"abstract":"<p><p>Background Sarcoidosis is a systemic, non-caseating granulomatous disease characterised by clinical and histopathological variability. Objective To review cases of cutaneous sarcoidosis and describe their clinical and histopathological features. Methods A retrospective study was conducted to analyse the clinical and histopathological frecords of all available skin biopsy slides signed out as 'sarcoidal tissue reaction' or 'sarcoidosis' from 2014 till 2022. Results A total of 25 cases were studied. The lesions were most commonly located on the head and neck (18 cases, 72%). Morphologically plaques (20%) were the most common, and the majority of cases had lesions of ≥2 distinct morphologies (44%). Histologically, classical naked granulomas were observed in 72% of cases. The granulomatous infiltrate was pandermal in 56% of cases, perivascular and interstitial in 16%, and perivascular, perieccrine, and interstitial in 12%. Granulomas with a 'leprosy' pattern were observed in 20% of cases. High-density granulomas (occupying >30% of the dermis) were present in 64% of cases. Fibrinoid necrosis and fibrosis between granulomas were observed in 16% and 8% cases, respectively. Inclusion bodies, such as asteroid and Schaumann bodies, were seen in 24% and 4% cases, respectively. Reticulin-rich granulomas were observed in 54% cases, while reticulin-poor granulomas were seen in 8.3%. Elevated serum ACE levels were found in 14 cases, and tuberculin skin test, conducted in 22 cases, was negative. Extracutaneous involvement was found in 11 cases, with 10 having pulmonary and 1 with pulmonary and splenic involvement. Limitation Retrospective nature of the study and small sample size. Conclusion Cutaneous sarcoidosis presents with a wide range of clinical and histomorphological features, necessitating clinico-histopathological correlation and ancillary investigations to establish the diagnosis and rule out mimickers.</p>","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"305-314"},"PeriodicalIF":3.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143257092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Large plaque-type blue naevus with subcutaneous cellular nodules (LPTBN-SN) in a young female: A rare entity.","authors":"Apoorva Sharma, Anuradha Bishnoi, Debajyoti Chatterjee, Keshavamurthy Vinay","doi":"10.25259/IJDVL_1192_2023","DOIUrl":"10.25259/IJDVL_1192_2023","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"393-395"},"PeriodicalIF":3.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141996848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Marginal micrographic surgery without tumour-frozen sections: A quicker margin control surgery for pigmented basal cell carcinomas.","authors":"Saurabh Singh, Nagbhushan Hegde","doi":"10.25259/IJDVL_92_2024","DOIUrl":"10.25259/IJDVL_92_2024","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"417-418"},"PeriodicalIF":3.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sirolimus in dermatology: Jack of many trades.","authors":"Sukhdeep Singh, Apoorva Sharma, Kittu Malhi, Dipankar De, Sanjeev Handa, Rahul Mahajan, Ujjwal Gorsi","doi":"10.25259/IJDVL_869_2023","DOIUrl":"10.25259/IJDVL_869_2023","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"S32-S34"},"PeriodicalIF":3.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141263401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mimickers of erysipelas and cellulitis: A narrative review.","authors":"Shreya K Gowda, Sonika Garg, Biswanath Behera, Vishal Thakur, Deepak Kumar Sahu","doi":"10.25259/IJDVL_160_2024","DOIUrl":"10.25259/IJDVL_160_2024","url":null,"abstract":"<p><p>A diffuse erythematous, edematous tender swelling with a distinct border and local rise in temperature suggest a morphological diagnosis of erysipelas-like eruption. While cellulitis and pseudocellulitis have an ill defined tender erythematous plaque. Erysipelas, and cellulitis are not a straightforward diagnosis as multiple cutaneous eruptions mimic erysipelas. It is important to have comprehensive knowledge about the different causes of erysipelas-like eruptions and pseudocellulitis to reach a diagnosis and treat appropriately. Many infectious diseases such as histoplasmosis, leishmaniasis, dermatophytosis, and infusion of chemotherapeutic agents result in erysipelas-like eruptions and pseudocellulitis. Malignancy-related dermatoses such as carcinoma erysipeloides, erysipeloides melanomatosum, and inflammatory dermatoses such as sweet syndrome, well syndrome, and Crohn's disease present as erysipelas-like eruption.</p>","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"346-355"},"PeriodicalIF":3.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Glimpses of gold: Unveiling the enigma of multiple lichen aureus.","authors":"Apoorva Sharma, Dipankar De, Debajyoti Chatterjee","doi":"10.25259/IJDVL_868_2023","DOIUrl":"10.25259/IJDVL_868_2023","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"S77-S78"},"PeriodicalIF":3.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141263398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bridging gaps in pediatric dermatology via telemedicine: An analytical cross-sectional study on 961 children in resource-limited areas of North India using the e-Sanjeevani 2.0 platform.","authors":"Kanya Rani Vashisht, Priyadarshini Sahu, Phani Priya Mandula, Nabaneeta Dash, Amit Agarwal, Richa Gupta, Biman Saikia","doi":"10.25259/IJDVL_1223_2024","DOIUrl":"https://doi.org/10.25259/IJDVL_1223_2024","url":null,"abstract":"<p><p>Background Pediatric tele-dermatology (PTD) offers a potential solution for delivering specialised dermatological care to children in remote areas. Objectives To evaluate the scope, utilisation, receptivity, and factors influencing the optimisation of PTD practice within the context of a developing country's demographic. Methods The study analysed 961 PTD consultations over six months, conducted in underserved areas of North India via an assisted telemedicine platform, e-Sanjeevani 2.0. Data were gathered cross-sectionally through standardised forms, complemented by a retrospective survey to capture the perceptions of referring healthcare providers (RHPs). Patient clinico-demographics and various consultation characteristics were assessed for their impact on clinical decision-making. Results Among the 961 cases studied (median age 5 years, IQR: 2-11; 52.1% female), the majority consisted of infections, infestations, and dermatitis, 1.35% cases were acute/emergency dermatoses managed empirically, and only 4.47% required referral. Friedman test revealed highly significant differences in perceived helpfulness amongst the four consultation variables (p<0.001) - image quality being the most helpful, followed by audiovisual/text interaction, multiple images, and past/medical/family history. Wilcoxon Signed Ranks tests indicated significant differences in perceived helpfulness between each pair of variables (p<0.001). The RHP survey reflected a strong endorsement of the process and a high perceived parent/guardian satisfaction rate (4.47 ± 0.87 on a 5-point scale). Limitations The study did not evaluate diagnostic or management concordance due to a lack of in-person evaluation. Other limitations included a low follow-up rate, short duration of study that may have missed seasonal variations in paediatric dermatoses. Additionally, clinical outcomes, cost-effectiveness, and technical factors such as connectivity and video quality were not assessed. Conclusion The findings support the use of real-time PTD to manage less complex, non-procedural cases, reduce in-person consultations, and improve access to paediatric dermatology care in resource-constrained settings. High-quality images and effective audiovisual communication are pivotal for its optimisation. The service had clinical and educational value and was well-received by parents and providers. The integration of eSanjeevani into India's healthcare infrastructure offers a functional foundation for larger scale expansion of PTD services. Further studies in diverse settings are needed to identify operational barriers to broader implementation and evaluate diagnostic accuracy through direct comparisons with in-person evaluations.</p>","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-7"},"PeriodicalIF":3.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144037033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}