{"title":"Disease severity scores in dermatology: An update of the various indices.","authors":"Atreyo Chakraborty","doi":"10.25259/IJDVL_592_2021","DOIUrl":"10.25259/IJDVL_592_2021","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"249-263"},"PeriodicalIF":3.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9770150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Box counting serial image index (BCSI) versus point counting serial image index (PCSI) in scoring melasma: A comparative, non-interventional validation study.","authors":"Papishetty Prathyusha, Jabeen Nihaa, Rangappa Vinutha, Pss Ranugha, N Srilakshmi, Shastry Veeranna, Garehatty Rudrappa Kanthraj","doi":"10.25259/IJDVL_1417_2024","DOIUrl":"10.25259/IJDVL_1417_2024","url":null,"abstract":"<p><p>Background Point counting serial image index (PCSI) is a scoring method used to assess the area and severity of melasma. Double tracing and the inability to assess scattered pigmentation are its limitations. Objectives To propose modifications to PCSI, the Box counting serial image index (BCSI) was compared and validated with PCSI. Methods In BCSI, a preset grid was placed, and serial images were captured. One speck of pigmentation was counted as one box. The area involved and time taken were recorded by the principal investigator and coinvestigator using BCSI and PCSI methods, respectively. The intensity of the pigmentation was recorded on a scale of 0-5. Melasma score = Area x Intensity of pigmentation. The difference in the total scores and time taken were analysed. Results A significant decrease (p<0.0003) in the total scores between baseline and first follow-up and baseline and second follow-up was observed in both methods. Similar to PCSI, BCSI was found to be sensitive to changes over time with treatment (p<0.0003). These p values were recalculated using Bonferroni corrections. The mean time taken by PCSI was significantly higher than BCSI (p < 0.0003). Limitations Grid placement over bony prominences and interference of facial hair. Conclusion BCSI overcomes the limitations of PCSI by directly capturing images and it is easy and rapid.</p>","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"211-216"},"PeriodicalIF":3.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144530853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Feeder nerve in a facial patch of leprosy.","authors":"Harish Kumar Sagar","doi":"10.25259/IJDVL_1625_2025","DOIUrl":"10.25259/IJDVL_1625_2025","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"247-248"},"PeriodicalIF":3.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146144595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intralesional measles, mumps, and rubella vaccine versus vitamin D for treatment of warts: A randomised clinical trial.","authors":"Manar Sallam, Amany Awad, Sara Hamdy, Ahmed State","doi":"10.25259/IJDVL_1669_2024","DOIUrl":"10.25259/IJDVL_1669_2024","url":null,"abstract":"<p><p>Background Warts are prevalent distressing skin growths caused by the human papillomavirus (HPV). These growths are commonly addressed using methods that destroy the tissue, including chemical cautery, electrocautery, or cryotherapy. These methods have many side effects in contrast to intralesional immunotherapy. Objectives This study was conducted to assess the effectiveness, safety, and tolerability of utilising the intralesional measles, mumps, and rubella (MMR) vaccine compared to vitamin D in warts treatment. Methods This randomised clinical trial enrolled 112 participants presenting with multiple warts. The participants were sub-divided into two groups through a random allocation process. Group Ⅰ (n=56) was administered 0.3 mL intralesional MMR vaccine, whereas group Ⅱ (n=56) was administered 0.3 mL intralesional vitamin D3 (equivalent to 15000 IU cholecalciferol). The injection was administered every two weeks into the most noticeable wart, requiring no more than five sessions until improvement. A follow-up period of six months was conducted after the final treatment session. Results A significantly higher percentage of complete response was noticed in the MMR group (80.4%) as compared with the vitamin D group (66.1%). Both groups had an average of four sessions, showing no significant difference. Regarding adverse effects, the MMR group demonstrated a significantly greater incidence of mild pain (96.4%) and injection site itching (12.5%) compared with the vitamin D group. After 6 months of follow-up, no significant difference was noticed in recurrence rates in both groups (3 cases; 5.4% in the vitamin D vs. 2 cases; 3.6% in the MMR group). Conclusion Intralesional MMR demonstrates greater efficacy than vitamin D in treating warts but with a higher incidence of tolerable side effects.</p>","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"285-291"},"PeriodicalIF":3.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144051054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yang Han, Mengmeng Li, Wenmin Fei, Ruixing Yu, Xiaoli Ning, Yong Cui
{"title":"The correlation of pigment content between dermoscopy and histopathology in basal cell carcinoma: A retrospective study.","authors":"Yang Han, Mengmeng Li, Wenmin Fei, Ruixing Yu, Xiaoli Ning, Yong Cui","doi":"10.25259/IJDVL_489_2025","DOIUrl":"10.25259/IJDVL_489_2025","url":null,"abstract":"<p><p>Background Pigmentation significantly impacts the diagnosis and management of basal cell carcinomas (BCCs). Although the dermoscopic-histopathologic correlations in BCCs have been studied, the relationship between quantitative pigment content has not been quantitatively assessed. Aim To quantify the correlation of pigment content between dermoscopy and histopathology in BCCs and to explore the relationship between dermoscopic features and clinical characteristics. Methods We retrospectively analysed clinical/dermoscopic/histopathologic images from 90 histopathologically confirmed BCCs. Pigment content was graded as: non-pigmented (0%), light (<30%), moderate (30-70%), and heavy (>70%) by visual assessment of the lesion involvement. Spearman correlation analysis was used to assess pigment content correlation, and Fisher's exact test was used to evaluate associations between dermoscopic and clinical characteristics. Results A moderate correlation (Spearman's r = 0.5028, p < 0.05) was observed between dermoscopic and histopathological pigment content. Dermoscopic features, including leaf-like areas, spoke-wheel-like structures, and ulceration, were associated with tumour location. Large blue-grey ovoid nests and leaf-like areas were associated with sex, while dotted vessels and leaf-like areas were associated with a disease course <24 months. Limitations The study was constrained by a small sample size and geographic homogeneity, primarily including Asian individuals from a high-BCC-prevalence region. Conclusion Quantitative correlation analysis confirms that dermoscopic pigmentation reflects both melanin density and architectural tumour aggregation, enabling non-invasive assessment of BCC biology.</p>","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"157-163"},"PeriodicalIF":3.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145309882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Erosive lesions with oat-flake-like scaling in a seborrheic pattern.","authors":"Judit Algarra Sahuquillo","doi":"10.25259/IJDVL_1210_2025","DOIUrl":"10.25259/IJDVL_1210_2025","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"241-243"},"PeriodicalIF":3.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146144585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}