{"title":"Leprosy literature in India: A journey through history and contemporary insights.","authors":"Bhushan Kumar, Hitaishi Mehta, Vignesh Narayan R, Tarun Narang, Sunil Dogra","doi":"10.25259/IJDVL_104_2025","DOIUrl":"https://doi.org/10.25259/IJDVL_104_2025","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-10"},"PeriodicalIF":3.2,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144530861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A novel mutation in poikiloderma with neutropenia- Clericuzio type in an adult female.","authors":"Himani Chawla, Shivani Bansal, Prashant Chhabra, Vishal Thakur","doi":"10.25259/IJDVL_1823_2024","DOIUrl":"https://doi.org/10.25259/IJDVL_1823_2024","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-3"},"PeriodicalIF":3.2,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144530849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ilaria Proietti, Chiara Battilotti, Francesco Fiorentino, Francesca Svara, Concetta Potenza
{"title":"Atypical fibroxanthoma successfully treated with a single dose of cemiplimab.","authors":"Ilaria Proietti, Chiara Battilotti, Francesco Fiorentino, Francesca Svara, Concetta Potenza","doi":"10.25259/IJDVL_1514_2024","DOIUrl":"https://doi.org/10.25259/IJDVL_1514_2024","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-3"},"PeriodicalIF":3.2,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144037030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intralesional measles, mumps, and rubella vaccine versus vitamin D for treatment of warts: A randomised clinical trial.","authors":"Manar Sallam, Amany Awad, Sara Hamdy, Ahmed State","doi":"10.25259/IJDVL_1669_2024","DOIUrl":"https://doi.org/10.25259/IJDVL_1669_2024","url":null,"abstract":"<p><p>Background Warts are prevalent distressing skin growths caused by the human papillomavirus (HPV). These growths are commonly addressed using methods that destroy the tissue, including chemical cautery, electrocautery, or cryotherapy. These methods have many side effects in contrast to intralesional immunotherapy. Objectives This study was conducted to assess the effectiveness, safety, and tolerability of utilising the intralesional measles, mumps, and rubella (MMR) vaccine compared to vitamin D in warts treatment. Methods This randomised clinical trial enrolled 112 participants presenting with multiple warts. The participants were sub-divided into two groups through a random allocation process. Group Ⅰ (n=56) was administered 0.3 mL intralesional MMR vaccine, whereas group Ⅱ (n=56) was administered 0.3 mL intralesional vitamin D3 (equivalent to 15000 IU cholecalciferol). The injection was administered every two weeks into the most noticeable wart, requiring no more than five sessions until improvement. A follow-up period of six months was conducted after the final treatment session. Results A significantly higher percentage of complete response was noticed in the MMR group (80.4%) as compared with the vitamin D group (66.1%). Both groups had an average of four sessions, showing no significant difference. Regarding adverse effects, the MMR group demonstrated a significantly greater incidence of mild pain (96.4%) and injection site itching (12.5%) compared with the vitamin D group. After 6 months of follow-up, no significant difference was noticed in recurrence rates in both groups (3 cases; 5.4% in the vitamin D vs. 2 cases; 3.6% in the MMR group). Conclusion Intralesional MMR demonstrates greater efficacy than vitamin D in treating warts but with a higher incidence of tolerable side effects.</p>","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-7"},"PeriodicalIF":3.2,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144051054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A case of a true human tail.","authors":"Meghana Reddy, Laxmisha Chandrashekar","doi":"10.25259/IJDVL_323_2025","DOIUrl":"https://doi.org/10.25259/IJDVL_323_2025","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1"},"PeriodicalIF":3.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Navya Anna Paul, Ramesh Bhat M, Beena Antony, Jyothi Jayaraman
{"title":"Antibiotic resistance and biofilm formation in Cutibacterium acnes: A descriptive cross-sectional study.","authors":"Navya Anna Paul, Ramesh Bhat M, Beena Antony, Jyothi Jayaraman","doi":"10.25259/IJDVL_539_2024","DOIUrl":"10.25259/IJDVL_539_2024","url":null,"abstract":"<p><p>Background The issue of antibiotic resistance in acne vulgaris has emerged as a significant concern in recent times. Though the ability of Cutibacterium acnes to form biofilms have been established, its role in acne vulgaris has yet to be ascertained. Aims This descriptive cross-sectional study was aimed to investigate the ability of C. acnes to form biofilms and its potential association with resistance to the commonly used antibiotics. Methods A total of 88 patients with acne vulgaris were selected for this study. Clinical examination and severity grading was done. The collected samples were analysed with Matrix-Assisted Laser Desorption Ionization Time of Flight Mass Spectrometry (MALDI-TOF-MS) and further subjected to biofilm testing using the microtiter plate assay. Results C. acnes were isolated from 43.1 of the samples (n = 38). The highest resistance was observed with azithromycin (73.7%) followed by clindamycin (65.8%), doxycycline (15.8%), ampicillin (31.6%) and minocycline (5.3%). Thirty-seven per cent of the isolates were resistant to at least two antibiotics, 63.2% of C. acnes had a weak capacity to form biofilms and more than 60 percent of the isolates showed resistance to atleast two types of antibiotics as well as weak biofilm forming capacity. Limitations Single-centre study, small sample, long-term follow-up of the patients was not done. In addition, this study is representative of only C. acnes species. Conclusion While C. acnes have the ability to create biofilms, its effectiveness in antibiotic resistance can be deemed as modest based on the findings of this study. It is important to consider alternative mechanisms such as genetic or biochemical plasticity that may contribute to antibiotic resistance.</p>","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"315-320"},"PeriodicalIF":3.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143257084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}