{"title":"Impact of social media-based follow-up nursing on itch severity and self-care in atopic dermatitis patients: A randomised controlled trial.","authors":"Cuimin Ren, Ruimin Wang, Yaohui Ma, Yun Yang, Haixia Ma, Chenglin Liu, Dandan Li","doi":"10.25259/IJDVL_595_2025","DOIUrl":"https://doi.org/10.25259/IJDVL_595_2025","url":null,"abstract":"<p><p>Background Atopic dermatitis (AD) is a chronic inflammatory skin disease requiring long-term management. Traditional care models often lack continuous support post-discharge. Aim To evaluate the impact of social media-based follow-up nursing on itch severity and self-care in AD patients. Methods This randomised controlled trial included 100 AD patients assigned to either a research group (n=49, received social media-based follow-up nursing) or a control group (n=49, received conventional nursing). Itch severity (numeric rating scale- NRS), eczema area and severity index (EASI), investigator's global assessment (IGA) and self-care ability (exercise of self-care agency scale) were assessed at baseline and 6 months post-intervention. The primary endpoint was the between-group difference in the mean change of the NRS score from baseline. Results At 6 months, patients in the research group showed significantly greater improvement. The mean reduction in the NRS score was 0.93 points greater in the research group than in the control group (95% CI: 0.52 to 1.34; p < 0.001). The research group also demonstrated significantly higher post-intervention total self-care ability scores (138.3 ± 9.00 vs. 111.21 ± 8.99, p<0.001). Limitations This was a single-centre study with a relatively short follow-up period. Conclusion Social media-based follow-up nursing effectively reduces itch severity and improves self-care in AD patients, suggesting its potential as a valuable tool for chronic disease management.</p>","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-7"},"PeriodicalIF":3.4,"publicationDate":"2026-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147634988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diego Abbenante, Davide Bertolla, Michela Tabanelli, Silvia Zago, Michela Starace
{"title":"Subungual dermal nerve sheath myxoma of the left thumb: Case report and literature review.","authors":"Diego Abbenante, Davide Bertolla, Michela Tabanelli, Silvia Zago, Michela Starace","doi":"10.25259/IJDVL_959_2025","DOIUrl":"https://doi.org/10.25259/IJDVL_959_2025","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-3"},"PeriodicalIF":3.4,"publicationDate":"2026-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147635051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Akriti Agrawal, B Haritha Meda, Jerene Mathews, Erukkambattu Jayashankar
{"title":"Linearly arranged nodules over the back in a young male.","authors":"Akriti Agrawal, B Haritha Meda, Jerene Mathews, Erukkambattu Jayashankar","doi":"10.25259/IJDVL_1333_2025","DOIUrl":"https://doi.org/10.25259/IJDVL_1333_2025","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-2"},"PeriodicalIF":3.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147635079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Apoorva Sharma, Dipankar De, Rahul Mahajan, Sanjeev Handa
{"title":"Keloidal scarring in pemphigus: A report of two cases.","authors":"Apoorva Sharma, Dipankar De, Rahul Mahajan, Sanjeev Handa","doi":"10.25259/IJDVL_1653_2025","DOIUrl":"https://doi.org/10.25259/IJDVL_1653_2025","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-3"},"PeriodicalIF":3.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147634963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Newshree Rout, Sivaranjini Ramassamy, Sreerekha Jinkala, Chengappa G Kavadichanda
{"title":"Predictors of severity of sequelae in discoid lupus erythematosus: A longitudinal cohort study.","authors":"Newshree Rout, Sivaranjini Ramassamy, Sreerekha Jinkala, Chengappa G Kavadichanda","doi":"10.25259/IJDVL_866_2025","DOIUrl":"https://doi.org/10.25259/IJDVL_866_2025","url":null,"abstract":"<p><p>Background The factors predicting the severity of sequelae of discoid lupus erythematosus (DLE) have not been studied. Objective To characterise factors predicting the severity of sequelae in DLE. Methods This longitudinal follow-up study (June 2023 to January 2025) included patients with DLE with/without other forms of cutaneous lupus erythematosus (CLE). Predictors of sequelae severity were analysed in 58 patients with follow-up of at least 3 months. The primary outcome was the factors associated with increased scar and dyspigmentation severity. Results Disease duration (p=0.001) and baseline cutaneous lupus erythematosus disease area and severity index (CLASI) scale/hypertrophy sub-score (p=0.016) determined scarring severity, while severity of pigmentation was predicted by disease duration (p=0.002) and baseline CLASI erythema sub-score (p<0.001). The mean follow-up was 8.38±5.89 months. Limitations Smoking status and quantitative data on photoprotective measures were not elicited from the participants. Conclusion The severity of sequelae is determined by disease duration and baseline disease activity scores.</p>","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-6"},"PeriodicalIF":3.4,"publicationDate":"2026-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147634993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Guillermo Pérez Limousin, Ane Jaka, Adrià Plana Pla, José Manuel Carrascosa
{"title":"Use of pulsed dye laser in iron infusion-induced dermal haemosiderosis.","authors":"Guillermo Pérez Limousin, Ane Jaka, Adrià Plana Pla, José Manuel Carrascosa","doi":"10.25259/IJDVL_1407_2025","DOIUrl":"https://doi.org/10.25259/IJDVL_1407_2025","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-2"},"PeriodicalIF":3.4,"publicationDate":"2026-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147635031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anoop Kumar, Rahul Mahajan, Niharika Srivastava, Shirin Bakshi, Laveena Kaushal, Adil Karim, Vinod Kumar, Dipankar De, Sanjeev Handa, Biman Saikia
{"title":"Patients with congenital ichthyosis show differential activation of IL-23/Th17 pathway among various disease subtypes - A single-centre experience.","authors":"Anoop Kumar, Rahul Mahajan, Niharika Srivastava, Shirin Bakshi, Laveena Kaushal, Adil Karim, Vinod Kumar, Dipankar De, Sanjeev Handa, Biman Saikia","doi":"10.25259/IJDVL_1749_2024","DOIUrl":"https://doi.org/10.25259/IJDVL_1749_2024","url":null,"abstract":"<p><p>Background Congenital ichthyosis is a rare genetic skin condition characterised by aberrant keratinisation. This study focused on assessing the differential expression of Th17-related cytokines in different subtypes of ichthyosis and its correlation with clinical features. Aim We aimed to compare the gene expression of Th17-related genes and serum levels of IL-17 and IL-23 cytokines of the ichthyosis subgroups in the Indian population. Methods We analysed blood and skin specimens from consecutively diagnosed patients with congenital ichthyosis along with age/sex-matched healthy controls using reverse transcription-polymerase chain reaction (RT-PCR), enzyme-linked immunosorbent assay (ELISA), as well as immunohistochemistry (IHC) for Th17/IL-23 pathway genes. Additionally, IFN-γ (Th1), IL-4 (Th2), and IL-17A (Th17)-dominant cell populations were measured using flow cytometry. Clinical severity was assessed using measures including the overall ichthyosis score (ICH score), which integrates erythema (E), scaling (S), and body surface area (BSA) scores. Results This study analysed interleukins in 48 congenital ichthyosis patients and 34 controls. We observed a significant upregulation of IL-17A and IL-23 in all patients, particularly autosomal recessive congenital ichthyosis (ARCI), X-linked recessive ichthyosis (XLRI), and Netherton syndrome (NS) subtypes. Similarly, serum levels of IL-17A were significantly augmented in all ichthyosis subtypes, with ARCI showing the highest increase. Whereas, an increase in IL-23 was only detected in ARCI. NS patients had significantly increased IL-22 levels. Limitations Our study included small sample size and lack of mRNA and cytokines expression in skin biopsy samples. Conclusion The study highlighted significant immunological alterations in interleukins associated with the Th17 pathway in different subtypes of congenital ichthyosis.</p>","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-9"},"PeriodicalIF":3.4,"publicationDate":"2026-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147635004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}