Lim Jo Anne, Adawiyah Jamil, Nur Izreena Ismail, Ummu Aiman Faisal, Mohan Arumugam
{"title":"A decade of trends in patch test allergen sensitisation from a dermatology centre in Southeast Asia.","authors":"Lim Jo Anne, Adawiyah Jamil, Nur Izreena Ismail, Ummu Aiman Faisal, Mohan Arumugam","doi":"10.25259/IJDVL_1076_2025","DOIUrl":"https://doi.org/10.25259/IJDVL_1076_2025","url":null,"abstract":"<p><p>Background Geographical and socioeconomic factors influence the type of allergens causing allergic contact dermatitis. Aim To investigate the changing trends of allergen sensitisation among patch-tested patients. Methods A retrospective study was performed on patients undergoing patch testing (PT) over 11 years (2012-2022). Data were retrieved from medical records. Results A total of 1035 patients were identified; 59 cases were excluded for incomplete data/wrong indication. Median age was 37 years (IQR 26-57) with bimodal peaks at 25-40 and 55-65 years; 69% were females. History of atopy was present in 76.5% patients. Common dermatitis sites were hands 436 (47.0%), feet 303 (32.7%), and head/ neck region 294 (31.7%). PT positivity rate was 885(89%). Top sensitising allergens were methyldibromoglutaronitrile (MDBGN), formaldehyde, potassium dichromate, nickel sulphate, and fragrance mix. In the cosmetic series, the main allergens were propylene glycol, thimerosal, and tert-butylhydroquinone. MDBGN showed an increasing trend, becoming the leading allergen from 2015-2020 before declining. Formaldehyde sensitisation rose until 2017, then stabilised. Potassium dichromate remained stable with peaks in 2015 and 2018. Cosmetic allergen sensitisation declined during the COVID-19 pandemic, likely due to reduced exposure. Limitations This single-centre study lacked extended PT readings beyond day 4, did not assess clinical relevance, and reflects sensitisation rather than confirmed allergic reactions. Conclusions Preservatives such as MDBGN, formaldehyde, and thimerosal were major sensitisers, alongside potassium dichromate, nickel, fragrance mix, and propylene glycol. Longitudinal analysis of allergen trends aids clinical management, guides PT updates, and directs regulatory decisions.</p>","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-7"},"PeriodicalIF":3.4,"publicationDate":"2026-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147634982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ear signs in dermatology: At a glance.","authors":"Aarushi Arunima, Sejal Jain, Tarun Narang","doi":"10.25259/IJDVL_1612_2025","DOIUrl":"https://doi.org/10.25259/IJDVL_1612_2025","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-5"},"PeriodicalIF":3.4,"publicationDate":"2026-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147634922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sunil Sethi, Gomseu Djoumsie Emmanuel Boris, Nandita Sharma, Rimjhim Kanaujia, Kuiate Jules Roger, Tamokou Jean de Dieu
{"title":"Prevalence and associated risk factors of Mycoplasma genitalium infection in women in Western Cameroon: A cross sectional study.","authors":"Sunil Sethi, Gomseu Djoumsie Emmanuel Boris, Nandita Sharma, Rimjhim Kanaujia, Kuiate Jules Roger, Tamokou Jean de Dieu","doi":"10.25259/IJDVL_370_2024","DOIUrl":"10.25259/IJDVL_370_2024","url":null,"abstract":"<p><p>Background Mycoplasma genitalium is implicated in genitourinary disorders in both men and women as a sexually transmitted infection (STI). This study aimed to ascertain the prevalence of M. genitalium and identify associated risk factors among women. Aim To investigate the prevalence of M. genitalium and identify various risk-factors associated with M. genitalium infection in women attending the clinic in Western Cameroon. Methods A cross-sectional study was conducted in hospitals from five districts of Western Cameroon on sexually active and non-menstruating women attending for antenatal, prenuptial and contraception consultations,between January 2020 and July 2020. Endocervical swabs (n = 680) were collected, and M. genitalium was detected using real-time PCR targeting the MgPa and pdhD genes. Results A total of 680 women, characterised by a mean age of 27.4 ± 7.5 years, were included in this study. The overall prevalence of the M. genitalium infection was 5.2%. Bivariate analysis revealed that having more than one sexual partner was independently associated with three times higher odds of prevalent M. genitalium infection (OR 2.9, 95% CI: 1.03-8.56). Limitations Cross-sectional design limits exploring temporal relationships with other STIs. Freezing specimens for a year until PCR testing may have compromised detection rates of M. genitalium. Conclusion This study contributes valuable data to the limited understanding of M. genitalium epidemiology. The findings may aid in the formulation of national clinical standards for testing and screening strategies, emphasising the importance of addressing associated risk factors in the targeted population.</p>","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"206-210"},"PeriodicalIF":3.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141996853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Elegy on the death of a pemphigus patient.","authors":"Atreyo Chakraborty","doi":"10.25259/IJDVL_1413_2025","DOIUrl":"10.25259/IJDVL_1413_2025","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"266"},"PeriodicalIF":3.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146144601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of aetiological profiles, treatment appropriateness, and outcomes of syndromic management for reproductive tract infections in women from urban clinics.","authors":"Deepti Tandon, Sowrabha Ramachandra, Shilpa Chandrakant Kerkar, Shahina Begum, Kiran Munne, Anushree Devashish Patil, Kimaya Mali, Niranjan Mayadeo, Jyotsna Shatrughan Dwivedi, Vikrant M Bhor","doi":"10.25259/IJDVL_355_2025","DOIUrl":"10.25259/IJDVL_355_2025","url":null,"abstract":"<p><p>Background While syndromic management is widely used in low-resource settings due to its cost-effectiveness and ease of patient care, growing concerns of antimicrobial resistance (AMR) and potential overtreatment highlight the need for regular aetiological testing to monitor treatment appropriateness. Aim To evaluate and compare syndromic management for reproductive tract infection for assessing treatment strategies. Methods In a prospective study, 250 sexually active, non-pregnant women aged 18-50 years, presenting with symptoms of lower genital tract infections were recruited as part of a prospective study from urban clinics in Mumbai. Participants underwent clinical and gynaecological examination, and standard syndromic management was provided. Samples were collected prior to treatment for Nugent scoring, Candida culture, and multiplex polymerase chain reaction (PCR) to detect sexually transmitted infections (STIs). Results The mean age of participants was 32.5 ± 6.6 years, with 51.2% (n=128) belonging to the upper-lower socioeconomic class. Vaginal discharge was the most common symptom (42%, n=105). Aetiological analysis identified causative agents in 90% (n=225) of cases, while 10% (n=25) showed no identifiable aetiology. The most prevalent pathogens were Ureaplasma parvum (47.2%) and Candida species (44.4%), followed by those causing bacterial vaginosis (39.2%). Among Candida species, Candida albicans (47.1%) and Candida krusei (45.2%) were most common. In contrast, Chlamydia trachomatis (3.2%) and Mycoplasma genitalium (1.2%) were less prevalent, and Neisseria gonorrhoeae was not detected. Syndromic management led to overtreatment rates exceeding 96% for these low-prevalence pathogens, raising concerns about AMR. Limitations Since this study is bounded to urban community clinics, it limits the expansion to rural scene, and AMR tests were not conducted due to the fastidious nature of microbes in the study and implementation challenges in resource limiting settings. Conclusion Syndromic management remains feasible in resource-limited settings; however, its limitations in addressing low-prevalence pathogens emphasises the need for periodic aetiological testing to improve diagnostic accuracy and guide appropriate treatment.</p>","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"164-170"},"PeriodicalIF":3.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144876592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}