Indian Journal of Dermatology Venereology & Leprology最新文献

{"title":"Efficacy and safety of dupilumab in Chinese patients aged over 60 years with bullous pemphigoid and comorbidities.","authors":"Shiyu Jin, Sha Jin, Shiwen Wang, Ping Wang","doi":"10.25259/IJDVL_579_2025","DOIUrl":"10.25259/IJDVL_579_2025","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-3"},"PeriodicalIF":3.4,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144876590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extensive cutaneous metastasis from salivary gland adenocarcinoma: A rare occurrence.","authors":"Xing Hu, Huiying Wang, Ruzhi Zhang","doi":"10.25259/IJDVL_543_2024","DOIUrl":"10.25259/IJDVL_543_2024","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-3"},"PeriodicalIF":3.4,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144876593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiple crateriform cutaneous nodules.","authors":"Sudharani Gaikwad, Apoorva Sharma, Debajyoti Chatterjee, Keshavamurthy Vinay","doi":"10.25259/IJDVL_692_2025","DOIUrl":"10.25259/IJDVL_692_2025","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-3"},"PeriodicalIF":3.4,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144876604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Progressive disseminated histoplasmosis mimicking acute cutaneous lupus erythematosus in an immunocompetent woman.","authors":"Lipsa Kumari, Vaishnavi Verma, Sonali Dixit, Neha Taneja","doi":"10.25259/IJDVL_156_2025","DOIUrl":"10.25259/IJDVL_156_2025","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-3"},"PeriodicalIF":3.4,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144876610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Granulomatous mycosis fungoides in a young man: A diagnostic challenge.","authors":"Sushant Agrawal, Rhea Ahuja, Sudheer Kumar Arava, Neha Taneja","doi":"10.25259/IJDVL_109_2025","DOIUrl":"10.25259/IJDVL_109_2025","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-3"},"PeriodicalIF":3.4,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144876597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Homozygous LMNA c.1579C>T mutation manifesting as mandibuloacral dysplasia type A in a pediatric patient.","authors":"Shihuan He, Jingjing Zeng, Jiangu Gong, Dongming Li, Youkun Lin","doi":"10.25259/IJDVL_1585_2024","DOIUrl":"10.25259/IJDVL_1585_2024","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-3"},"PeriodicalIF":3.4,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144876598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mapping the dermoscopic features of the normal face: Findings from 200 subjects with skin of colour.","authors":"Sushant Agrawal, Ananya Sharma, M Ramam, Sujay Khandpur, Binod K Khaitan, Ashish Datt Upadhyay, Vishal Gupta","doi":"10.25259/IJDVL_107_2025","DOIUrl":"10.25259/IJDVL_107_2025","url":null,"abstract":"<p><p>Background Dermoscopy can potentially obviate the need for skin biopsy, particularly at cosmetically sensitive sites such as the face. While dermoscopic features of various skin diseases are well described, information on dermoscopic findings in normal skin is limited. Objectives To study the dermoscopic features of the normal face. Methods Two-hundred subjects without any facial skin disease were included in the study. Dermoscopic findings of different facial sites (forehead, bilateral zygomatic areas, bilateral cheeks, nose and chin) were evaluated using a hand-held dermoscope (Heine Delta 30) by two investigators. Dermoscopic differences between different facial sites, gender and age groups were compared. Results Most (n=156, 78%) subjects had Fitzpatrick skin type IV-VI. A background pseudonetwork was present in a majority at all the sites, except the nose (62-85% vs 41%, p<0.001). An accentuated patchy pseudonetwork was seen most commonly on the cheeks and zygoma (18-21%, p<0.001). Follicles were of uniform size and present at uniform distances in a majority at all sites, but were more commonly variable on the nose (53-70%, p<0.001). Follicular brown pigmentation was seen in 27-37% at all sites, except the forehead (9%, p<0.001). Brown circles around adnexal openings were seen most commonly on the nose (41%, p< .001). A 'dot in circle' morphology was seen most commonly on the zygoma and cheeks (25-30%, p<0.001). Vessels were more commonly seen on the cheeks (48%) and chin (27%) as compared to other sites (p<0.001). The most common vessel pattern was a linear, non-branching one. Focussed or dotted vessels were not seen at any site. White reticular lines were seen almost exclusively on the nose (15%, p<0.001). Accentuated patchy pseudonetwork, follicular plugs and brown circles around adnexal openings were more common in males, while follicular brown pigmentation was statistically significantly more common in females. Accentuated patchy pseudonetwork, follicular plugs, follicular brown pigmentation, brown circles around adnexal openings, vessels, and reticular white lines became more common with advancing age. Limitations Relatively small sample size, smaller proportion of elderly subjects, and a majority of the subjects belonging to darker skin phototypes (V-VI) Conclusion Knowledge of variations in normal dermoscopic findings of the face will help dermatologists in distinguishing abnormal from normal, and improve the interpretation of dermoscopic findings of facial skin lesions.</p>","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-8"},"PeriodicalIF":3.4,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144876603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation of mast cell density and histopathological characteristics of syringoma: An immunohistochemical study.","authors":"Tae Min Kim, Soyun Cho","doi":"10.25259/IJDVL_1893_2024","DOIUrl":"10.25259/IJDVL_1893_2024","url":null,"abstract":"<p><p>Background Syringoma, a benign skin tumour characterised by stromal fibrosis and epithelial encirclement, suffers from limited treatment options. Aim This study aimed to analyse the correlation between mast cell density and histological features of syringomas, particularly stromal fibrosis and epidermal pigmentation. Methods Immunohistochemical staining with CD117 and estrogen receptor (ER)-α was performed in 49 samples from 47 patients of syringoma to assess mast cell density and ER-α expression. Results The study revealed a female predominance (4.2:1), with a median age of 42 years (range, 21-80 years) and an onset at the age 28.5 years (5-74). All 49 cases were localised, primarily to the eyelid (67.3%), followed by the face (18.4%), vulva (8.2%), and axilla/extremities (6.1%). Epidermal thickness correlated directly with tumour thickness (r=0.652, p<0.01), which varied across anatomical sites. Mast cell density significantly correlated with basal pigmentation (r=0.338, p=0.02), stromal fibrosis (r=0.308, p=0.03), and stromal ER-α (r=0.249, p=0.03), suggesting their involvement in syringoma pathogenesis. Acanthosis, basal hyperpigmentation, and stromal fibrosis were prevalent in 83.7%, 83.7%, and 100% of patients, respectively. ER-α positivity was observed in the syringoma stromal area in 30 cases (61.2%), whereas positivity in the tumour cell area was confirmed in only 3 cases (6.1%). Limitations The retrospective nature of the analysis and the limited sample size may affect the generalisability of the findings. Conclusion Our findings highlight a significant correlation between mast cells and stromal fibrosis, as well as basal hyperpigmentation in syringomas. This suggests the potential involvement of mast cells in their pathomechanism. Furthermore, the correlation of mast cell density with stromal ER-α may explain the female predominance.</p>","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-7"},"PeriodicalIF":3.4,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144876585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term efficacy and safety of JAKi in refractory livedoid vasculopathy.","authors":"Yue Xiao, Yiyi Wang, Ping Tan, Dingke Wen, Shuzhen Zhao, Wei Li","doi":"10.25259/IJDVL_1218_2024","DOIUrl":"10.25259/IJDVL_1218_2024","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-3"},"PeriodicalIF":3.4,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144876602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bidirectional association between vitiligo and melasma: A large-scale population-based study.","authors":"Shany Sherman, Hadar Duskin-Bitan, Tamir Agiv, Danielle Bar, Lilach Marom-Haham, Assi Levi, Daniel Mimouni, Li-Chi Chen, John E Harris, Jen Barak Levitt, Yochai Schonmann, Arnon D Cohen, Doron Netzer","doi":"10.25259/IJDVL_1828_2024","DOIUrl":"10.25259/IJDVL_1828_2024","url":null,"abstract":"<p><p>Background The dual diagnosis of vitiligo and melasma and their association has hardly been studied. Objective To test our hypothesis of an independent bidirectional association between vitiligo and melasma. Methods A population-based study was conducted on 24,436 patients with vitiligo and 119,205 matched comparators. Both a retrospective cohort design and a nested case-control design were used, with the calculation of adjusted hazard ratios (HRs) and odds ratios (ORs). Results The incidence of melasma per 1000 person-years was 1.38 (95% CI 1.22-1.54) in the vitiligo group and 0.88 (95% CI 0.84-0.96) in the comparison group. Patients with vitiligo had a 60% increased risk of developing melasma regardless of hormonal treatment, phototherapy, and thyroid disorders (adjusted HR, 1.58; 95% CI, 1.35-1.86). The prevalence of pre-existing melasma was higher in patients with vitiligo than in matched comparators (0.9% vs. 0.5%, P<0.001). Melasma was associated with a 30% increase in the odds of developing vitiligo (adjusted OR 1.32; 95% CI 1.12-1.55), regardless of hydroquinone treatment. Limitations Retrospective data collection. Conclusion A bidirectional association between vitiligo and melasma was observed. Treatment strategies for individuals with a dual diagnosis warrant further investigation.</p>","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-7"},"PeriodicalIF":3.4,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144876582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}