Jayne Pickering, Wen Shao, Scott Weich, Caroline F. Dalton, Myles Jones, Chris D. J. Taylor, Markus Reuber, Jessica Kingston, Chris Gibbs, Richard P. Bentall
{"title":"Developing Trace: A Transdiagnostic Screening Tool for Early Detection of a Pluripotent at-Risk Mental State","authors":"Jayne Pickering, Wen Shao, Scott Weich, Caroline F. Dalton, Myles Jones, Chris D. J. Taylor, Markus Reuber, Jessica Kingston, Chris Gibbs, Richard P. Bentall","doi":"10.1002/mpr.70046","DOIUrl":"10.1002/mpr.70046","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Early identification of individuals at risk for developing mental health disorders is critical for timely intervention, reducing distress and improving outcomes. This study outlines the development and preliminary validation of ‘TRACE’, a short self-report measure designed to detect a pluripotent at-risk mental state (PARMS). The measure captures a range of subthreshold symptoms and traits associated with emerging manifestations of mania, psychosis and borderline personality disorder.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A sample of 2037 general-population adolescents and young adults (aged 14–36) completed TRACE questions and other psychometrics.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Exploratory Graph Analysis, undertaken on one-half of the dataset, generated a three-factor structure that was successfully replicated in the other half of the data, via confirmatory factor analysis. The final 26-item scale has acceptable model fit (with a scaled CFI of 0.93, TLI of 0.92, with acceptable-to-good error, RMSEA of 0.073) and good concurrent validity with other relevant psychometrics, such as neuroticism and loneliness (<i>r</i> = 0.29 and 0.43, respectively).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>These findings suggest that the tool may be useful in identifying individuals with a broad, pluripotent vulnerability to develop severe mental health disorders. Future research will focus on validating the tool longitudinally and across diverse populations to assess its predictive utility and clinical value.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50310,"journal":{"name":"International Journal of Methods in Psychiatric Research","volume":"34 4","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12675136/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145670674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jurriaan F. M. Strous, Gijs H. J. Roelandt, Jens H. van Dalfsen, Jeanine Kamphuis, Radboud M. Marijnissen, Robert A. Schoevers
{"title":"The Ketamine Trial for Acute Suicidality (KETA): Study Protocol of a Double-Blind Randomized Placebo-Controlled Superiority Trial on Intranasal Racemic Ketamine Compared to the Active Placebo Intranasal Midazolam as Treatment for Acute Suicidality","authors":"Jurriaan F. M. Strous, Gijs H. J. Roelandt, Jens H. van Dalfsen, Jeanine Kamphuis, Radboud M. Marijnissen, Robert A. Schoevers","doi":"10.1002/mpr.70044","DOIUrl":"10.1002/mpr.70044","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Suicidality is a transdiagnostic entity in patients with and without psychiatric disorders. Ketamine is a novel treatment for treatment-resistant depression with favorable effects on related suicidality in this population. Little is known about the effects of ketamine on suicidality as a distinct phenomenon.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To assess whether a dose of 75 mg intranasal (IN) ketamine reduces acute suicidality relative to a 4 mg intranasal dose of the active placebo midazolam, 180 min after administration.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods/design</h3>\u0000 \u0000 <p>A double-blind randomized placebo-controlled trial (<i>N</i> = 100) will assess the efficacy of fixed-dose IN racemic ketamine in patients presenting with acute suicidality, regardless of psychiatric diagnosis. Participants receive a single IN dose of either racemic ketamine (75 mg) or midazolam (4 mg) along with treatment as usual. The primary outcome is the reduction in suicidal ideation as measured by the Beck Scale for Suicide Ideation (BSSI) at 180 min. Secondary outcomes include depression severity with the Montgomery Åsberg Depression Rating Scale (MADRS) and tolerability with the Systematic Assessment for Treatment Emerging Effects (SAFTEE) as well as blood-based and neuroimaging markers.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>This study design considers key aspects such as patient selection, ketamine formulation, clinical management, and the follow-up time points. Potential risks, limitations, and future considerations are additionally discussed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Trial Registration</h3>\u0000 \u0000 <p>EudraCT 2020-002905-24, registered 6 October 2021</p>\u0000 </section>\u0000 </div>","PeriodicalId":50310,"journal":{"name":"International Journal of Methods in Psychiatric Research","volume":"34 4","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12627964/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145551668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jie Luo, Wen Shao, Yuanzhen Wu, Huanhuan Huang, Gaoyang Xu, Yanjie Qi, Paul Overton, Yi Zheng, Fan He
{"title":"A Network Analysis of ADHD and ASD Symptoms in Chinese Children: Insights on Age and Gender Differences","authors":"Jie Luo, Wen Shao, Yuanzhen Wu, Huanhuan Huang, Gaoyang Xu, Yanjie Qi, Paul Overton, Yi Zheng, Fan He","doi":"10.1002/mpr.70042","DOIUrl":"10.1002/mpr.70042","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>This study aimed to explore the transdiagnostic interactions between ADHD and ASD symptoms in Chinese children, identifying core and bridging symptoms, and examining differences in symptom networks across gender and age subgroups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>Using data from a nationwide mental health survey of 71,217 Chinese children (mean age = 11.49, SD = 2.82), a symptom network analysis was conducted. ADHD and ASD symptoms were assessed via the Child Behavior Checklist (CBCL), with ASD items selected from an empirically derived CBCL autism scale. Network estimation was performed using the Glasso algorithm, and community detection was achieved through exploratory graph analysis (EGA). Network comparison tests (NCT) were used to evaluate differences in network structure and connectivity between gender (male vs. female) and age (younger vs. older) subgroups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Inattentive symptoms (I8 “Cannot concentrate,” I78 “Inattentive/easily distracted”) emerged as central bridging nodes linking ADHD and ASD symptoms. Three stable communities were identified: (1) an inattentive/internalizing cluster reflecting overlapping ADHD-inattentive and ASD features, (2) a hyperactive/impulsive and immature behavior cluster, and (3) a social withdrawal/low energy cluster representing core ASD features. Females exhibited significantly higher network connectivity than males (global strength: <i>S</i> = 1.05, <i>p</i> = 0.03), with tighter symptom interplay. Older children showed greater ADHD-ASD symptom overlap, though global strength differences were non-significant (<i>S</i> = 0.70, <i>p</i> = 0.13).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Two inattentive symptoms (I8 and I78) emerged as among the most strongly connected items in the combined ADHD–ASD symptom profile, suggesting that attentional difficulties could play an important role in the psychopathological mechanisms underlying both conditions. Nevertheless, this cross-sectional finding does not establish causality; longitudinal and intervention studies remain necessary. Screening approaches tailored to gender differences and local cultural context could improve identification of these symptoms in Chinese children and adolescents. The present findings may also guide future refinements in school mental-health support and related policy development.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50310,"journal":{"name":"International Journal of Methods in Psychiatric Research","volume":"34 4","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12627236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145551673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Body Dysmorphic Disorder Questionnaire: Arabic Adaptation and Validation in Dermatology Population","authors":"Pascale Salameh, Jinane El Khoury, Marwa Hallal, Elissa Bader, Raneem Abed El Sater, Micheline Maamari, Maya Habre, Rami Abadi, Grace Obeid, Jihane Abou Rahal, Rudy Abi-Habib","doi":"10.1002/mpr.70045","DOIUrl":"10.1002/mpr.70045","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Body Dysmorphic Disorder (BDD) is a psychiatric condition characterized by excessive preoccupation with perceived flaws in physical appearance, often encountered in dermatologic settings.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>This study aims to validate the Arabic Body Dysmorphic Disorder Questionnaire (BDDQ), used in the dermatologic setting.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Using previous versions of BDDQ, we developed a scale that considers the dermatologic setting and conditions and translated it into Arabic. The new tool was assessed for its construct, structural, and criterion validity and reliability.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The newly developed tool had an appropriate construct validity; it was unidimensional (57% variance explanation), with excellent internal consistency (Cronbach alpha = 0.889). The structural (significant inter-item and item-scale Spearman correlation coefficients) and criterion validity measures (AUC = 0.869) were also appropriate. Compared to a physician diagnosis of BDD, two cut-off values were defined for the scale: 11.5 for screening purposes (Se = 100%; Sp = 31%), and 18.5 for diagnostic purposes (Se = 83% and Sp = 83.5%).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This study developed and validated a quantitative scale in a dermatology setting, the Arabic BDDQ scale. Further studies are recommended to confirm the scale's efficiency for screening and diagnostic purposes.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50310,"journal":{"name":"International Journal of Methods in Psychiatric Research","volume":"34 4","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mpr.70045","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145460525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Qian Xiao, Liying Shen, Fangling Li, Furong Jiang, Bei Xu
{"title":"Exploration of the Value of Optical Coherence Tomography (OCT) and OCT Angiography in Differentiating Between Major Depressive Disorder and Borderline Personality Disorder","authors":"Qian Xiao, Liying Shen, Fangling Li, Furong Jiang, Bei Xu","doi":"10.1002/mpr.70043","DOIUrl":"10.1002/mpr.70043","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Major depressive disorder (MDD) and borderline personality disorder (BPD) are psychiatric conditions with overlapping clinical features but distinct pathologies. This study aims to explore the microvascular changes in superficial retinal capillary plexus (SRCP) in patients between MDD and BPD using Optical Coherence Tomography (OCT) and Optical coherence tomography angiography (OCTA), as well as determine their clinical diagnostic value.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The study involved 35 MDD patients, 36 BPD patients, and 36 healthy controls (HCs). OCTA and OCT were used to assess macular vessel density (MVD) and peripapillary vessel density (PVD), retinal nerve fiber layer (RNFL), and central retinal thickness (CRT). The study also evaluated the correlation of these ocular parameters with clinical symptoms.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Both MDD and BPD patients showed significant reductions in MVD, RNFL and CRT compared to HCs (all <i>p</i> < 0.05). BPD patients exhibited more pronounced decreases in the foveal area, RNFL and CRT than MDD patients (all <i>p</i> < 0.05). These ocular changes were associated with BPD symptom severity (all <i>p</i> < 0.05). The RNFL and CRT demonstrated potential as diagnostic markers for BPD (AUROCs of 0.625 and 0.695, <i>p</i> < 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>OCT and OCTA might differentiate between MDD and BPD by identifying specific ocular changes, suggesting distinct neurobiological mechanisms for each disorder. These technologies hold promise for improving diagnostic accuracy.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50310,"journal":{"name":"International Journal of Methods in Psychiatric Research","volume":"34 4","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12586372/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145446410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alice Hirdes, Wagner de Lara Machado, Priscila Carvalho Fogaça, Fabiana Rosa de Oliveira Nink, Richard Steiner Salvato, Elton Luiz Ferlin, John P. Hirdes
{"title":"interRAI Quality of Life for Mental Health and Addictions: Psychometric Properties and Differences Across Age, Gender, and Service Settings in Brazil","authors":"Alice Hirdes, Wagner de Lara Machado, Priscila Carvalho Fogaça, Fabiana Rosa de Oliveira Nink, Richard Steiner Salvato, Elton Luiz Ferlin, John P. Hirdes","doi":"10.1002/mpr.70040","DOIUrl":"https://doi.org/10.1002/mpr.70040","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Estimate the psychometric properties of the interRAI Quality of Life for Mental Health and Addictions (interRAI QOL) instrument with users of Psychosocial Care Centers and participants of therapeutic groups in Primary Health Care, exploring age, gender, and service settings differences in quality of life.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>This quantitative study was conducted with 617 users from Psychosocial Care Centers and Primary Care services in two Brazilian states, Rio Grande do Sul and Rondônia. Data collection was carried out using the interRAI QOL. Confirmatory factor analysis and reliability assessment were performed using McDonald's Omega index. Non-parametric tests, including Mann-Whitney and Kruskal-Wallis, were conducted to compare the Quality-of-Life dimensions among participants based on age, gender, and care unit.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The confirmatory factor analysis indicated a good fit for the hypothesized model (CFI = 0.97, RMSEA = 0.08). Reliability was adequate for all subscales according to McDonald's Omega, ranging from 0.71 to 0.88. Gender differences were observed in the well-being and health dimensions, while all dimensions except support showed significant differences based on age group. The care unit location also revealed significant differences across all dimensions. Participants from Psychosocial Care Center Alcohol and Drugs and from Primary Health Care show better QOL profiles than in other settings and regions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The interRAI QOL demonstrated adequate psychometric properties and proved to be a valuable new instrument for assessing quality of life among individuals receiving care in the psychosocial care network.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50310,"journal":{"name":"International Journal of Methods in Psychiatric Research","volume":"34 4","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mpr.70040","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145406526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnostic and Predictive Utility of Plasma Phosphoethanolamine Levels in Depressive Disorder: A Naturalistic Observational Study","authors":"Noriyuki Kawamura, Akinori Nakata, Tsuyoto Harada, Yoshiaki Ohashi, Hajime Sato, Kazunori Sasaki, Shoichiro Tsugane","doi":"10.1002/mpr.70041","DOIUrl":"10.1002/mpr.70041","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Plasma phosphoethanolamine (PEA) has been proposed as a potential biomarker for depressive disorder. To further assess its diagnostic utility and relevance across psychiatric conditions, we conducted a larger observational study in a psychiatric primary care setting.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Between 2013 and 2020, 576 patients underwent DSM-5-based psychiatric assessments. Plasma PEA levels were measured in 295 patients with depressive disorders, 264 with other psychiatric disorders, and 17 with physical illnesses.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>PEA demonstrated moderate or high diagnostic accuracy for depressive disorder (AUC = 0.81, 95% CI: 0.78–0.85). Lower PEA levels were significantly associated with depression (OR = 16.30, <i>p</i> < 0.001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>These findings suggest that plasma PEA concentration may serve as a useful biomarker for depressive disorder. Further studies are warranted to explore its potential relationship with white matter pathology in psychiatric conditions.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50310,"journal":{"name":"International Journal of Methods in Psychiatric Research","volume":"34 4","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12559855/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145379648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Feten Fekih-Romdhane, Ons Ghorbel, Carlos Laranjeira, Majda Cheour, Frederic Harb, Souheil Hallit
{"title":"Validation of the Eight-Item Paranoid Thoughts Scale (GPTS-8) in Tunisian Arab Adults","authors":"Feten Fekih-Romdhane, Ons Ghorbel, Carlos Laranjeira, Majda Cheour, Frederic Harb, Souheil Hallit","doi":"10.1002/mpr.70039","DOIUrl":"https://doi.org/10.1002/mpr.70039","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Growing research indicated that it is highly valuable and clinically beneficial to quantitatively measure and detect the potential presence of paranoid thinking. Among the various existing self-report instruments to measure paranoia, the Green et al. Paranoid Thoughts Scale (GPTS) was recommended as having the most well-defined, clearly articulated construct underlying its items, and the strongest psychometric qualities in general and clinical population samples. Yet, the psychometric performance of the GPTS remains unknown in the Arab language and culture. To address this gap, our study aimed to explore the psychometric properties of an Arabic translation of the shortest version of the scale (i.e., the GPTS-8).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A cross-sectional study was conducted. Data were collected during the period September 1st 2024 to January 31th 2025. A total of 552 Arabic-speaking general population adults from Tunisia aged 25.81 ± 4.86 years participated.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Analyses provided support for a bidimensional model, with a first dimension referring to ideas of persecution and a second one corresponding to ideas of reference. The internal consistency reliability coefficients were high, with both Cronbach's alpha and McDonald's <i>ω</i> reported to be 0.83 for ideas of persecution and 0.83 for ideas of reference. Measurement invariance was established for both subscales, implying that the Arabic GPTS-8 measures the same underlying construct of paranoia in the same way across male and female respondents. Finally, paranoia scores correlated positively with psychotic experiences scores, indicating convergent validity, as well as with depression, anxiety and insomnia scores, supporting the concurrent validity of the scale.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>By translating and validating GPTS-8 for the first time in Arabic, this study contributes to rendering the tool available to a broader array of clinicians and researchers who work with Arabic-speaking people. We believe the new Arabic version of the GPTS-8 will provide further encouragement to research and development in this yet-unexplored field among Arabic-speakers.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50310,"journal":{"name":"International Journal of Methods in Psychiatric Research","volume":"34 4","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mpr.70039","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145297393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Philippa Lynn Mayer, Anna Lisa Westermair, Nele Assmann, Joos Bloo, Natalia Calvo, Chiara De Panfilis, Eva Fassbinder, Marc Ferrer, Gitta Jacob, Juliette Richetin, Anja Schaich, Emanuele Preti, Jan Philipp Klein, Arnoud Arntz
{"title":"Psychometric Evaluation of the Borderline Personality Disorder Checklist","authors":"Philippa Lynn Mayer, Anna Lisa Westermair, Nele Assmann, Joos Bloo, Natalia Calvo, Chiara De Panfilis, Eva Fassbinder, Marc Ferrer, Gitta Jacob, Juliette Richetin, Anja Schaich, Emanuele Preti, Jan Philipp Klein, Arnoud Arntz","doi":"10.1002/mpr.70029","DOIUrl":"10.1002/mpr.70029","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Borderline Personality Disorder (BPD) is a severe and disabling condition. The Borderline Personality Disorder Checklist (BPDCL) was designed to specifically assess the subjective burden of a patient due to BPD symptoms. Various translations have been developed, but an assessment of the psychometric properties of these translations is needed. The aim was to examine the psychometric qualities of the BPDCL across different languages (i.e., Italian, Dutch, German, Spanish, English, and Greek).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Secondary data was used by reaching out to various researchers, who administered the BPDCL in previous studies. Five studies (<i>N</i> = 3199) conducted in Spain, Germany, Italy, the Netherlands, Australia, England, and Greece, were included in the current data set. The BPDCL was administered to BPD patients (<i>N</i> = 1131), Axis I disorder patients (<i>N</i> = 57), patients with other personality disorders (<i>N</i> = 225), and healthy controls (<i>N</i> = 1786). Item analyses and analyses assessing the known-groups and convergent validity were performed to investigate the psychometric properties of the checklist.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Each version of the BPDCL, differing in language, demonstrated high-reliability coefficients (Cronbach's Alpha ranged from 0.93 to 0.96 and was 0.96 for the entire sample). The correlations between the BPDCL and other instruments, used in the studies, were weak to strong. Correlations greater than 0.55 were observed between the BPDCL and the scales BPDSI, SCL-90 and the BSI. In addition, the BPDCL seems to differentiate well between diagnostic groups. BPD patients scored the highest, followed by patients with other personality disorders, who in turn scored higher than Axis I disorder patients and healthy controls.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>In general, the BPDCL possesses good psychometric properties and seems to be an adequate self-report instrument to measure the subjective burden of BPD patients.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50310,"journal":{"name":"International Journal of Methods in Psychiatric Research","volume":"34 3","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mpr.70029","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145139114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Madeleine Benton, Elana Payne, Nabiha Waheed, Katrina Turner, Helen R. Murphy, Helen Skouteris, Khalida Ismail, Sergio A. Silverio
{"title":"The Psychosocial and Healthcare Utilisation Experiences of Women With Gestational Diabetes Mellitus From Diagnosis to 12 Months Postnatal: A Protocol for a Qualitative, Longitudinal Interview Study","authors":"Madeleine Benton, Elana Payne, Nabiha Waheed, Katrina Turner, Helen R. Murphy, Helen Skouteris, Khalida Ismail, Sergio A. Silverio","doi":"10.1002/mpr.70038","DOIUrl":"10.1002/mpr.70038","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Gestational diabetes mellitus (GDM) affects a significant and growing proportion of women each year. We know little about how their needs and experiences change over the perinatal period. This study aims to explore the psychosocial and healthcare experiences of women with a GDM diagnosis from pregnancy to 12-month postnatal.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This is a qualitative, longitudinal study comprising of individual interviews with women diagnosed with GDM who live in the UK at three time points: 35-weeks’ gestation; 3-months postnatal; 12-months postnatal. Data will be analysed using template analysis. Comparisons will be made both between participants and timepoints to allow for biographical and temporal interpretations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>This study will provide in-depth insights into women's lived-experiences, psychosocial needs, and interactions with healthcare services. Particular attention will be given to the transition between antenatal and postnatal periods.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Study findings will support the co-development of a tailored mother-infant dyad intervention grounded in women's needs and preferences across the perinatal period, aimed at improving long-term health outcomes for women and their children with a focus on diabetes prevention.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50310,"journal":{"name":"International Journal of Methods in Psychiatric Research","volume":"34 3","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mpr.70038","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}