International Journal of Methods in Psychiatric Research最新文献

{"title":"The Latent Structure of Depression and Anxiety Symptoms: A Bifactor Exploratory Structural Equation Model of the PHQ-9 and GAD-7 in Primary Care","authors":"Gabriel Esteller-Collado,&nbsp;Maider Prieto-Vila,&nbsp;Celia Antuña-Camblor,&nbsp;María Carpallo-González,&nbsp;César González-Blanch,&nbsp;Paloma Ruíz-Rodríguez,&nbsp;Juan Antonio Moriana,&nbsp;Leonardo Adrián Medrano,&nbsp;Antonio Cano-Vindel,&nbsp;Roger Muñoz-Navarro","doi":"10.1002/mpr.70089","DOIUrl":"10.1002/mpr.70089","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>The high comorbidity between depression and anxiety challenges traditional nosological models. In order to better reflect this overlap, dimensional approaches seek to clarify whether these symptoms reflect a single underlying construct of general distress or a more complex multidimensionality. The aim was to examine the underlying structure of depression and anxiety symptoms, measured by the PHQ-9 and GAD-7, by estimating and comparing three factor models: one-factor, two-factor correlated, and bifactor.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Data from 1704 primary care (PC) patients from the PsicAP clinical trial were analysed. Dimensionality was assessed using hierarchical Exploratory Graph Analysis (EGA), and models were estimated using Exploratory Structural Equation Modelling (ESEM). Model fit was compared using the <i>χ</i>², CFI, TLI, RMSEA, and SRMR indices.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The bifactor model offered the most acceptable comparative fit to the data (CFI = 0.956; TLI = 0.928; RMSEA = 0.076; SRMR = 0.028). Bifactor indices revealed a relevant but not dominant general factor (ECV = 0.40), indicating it does not account for sufficient variance to justify an essentially unidimensional interpretation. Furthermore, the specific factors of depression and anxiety emerged as well-defined constructs (<i>H</i> &gt; 0.75) with modest reliable specific variance (ωHS: 0.22 and 0.27, respectively).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>The findings suggest a hierarchical structure where a general factor of distress coexists with specific factors. This suggests the potential utility of considering a multi-level perspective in clinical assessment, accounting for both shared distress and specific symptom profiles.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50310,"journal":{"name":"International Journal of Methods in Psychiatric Research","volume":"35 2","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mpr.70089","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148228833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Social and Clinical Factors Associated With Antipsychotic Medication Discontinuation in Patients With Schizophrenia","authors":"Zhengquan Chen,&nbsp;Yiming Wu,&nbsp;Zuowei Wang,&nbsp;Jun Wang,&nbsp;Chao Jiang,&nbsp;Wenchao Shen,&nbsp;Yanting Zheng,&nbsp;Yi Wu","doi":"10.1002/mpr.70082","DOIUrl":"10.1002/mpr.70082","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This study aims to identify social and clinical factors associated with antipsychotic medication discontinuation in patients with schizophrenia.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This cross-sectional case-control study comprised 111 schizophrenia patients, including 55 who discontinued medication on their own initiative and 56 matched continuous-treatment patients. Assessed factors covered demographics, clinical profiles, and scores from the Positive and Negative Syndrome Scale (PANSS), the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS), and the Personal and Social Performance (PSP) scale.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Patients in the discontinuation group demonstrated significantly higher employment rates (<i>χ</i>² = 24.514, <i>p</i> &lt; 0.001) and marriage rates (<i>χ</i>² = 14.970, <i>p</i> = 0.002) compared to those in the continuous treatment group. The continuous treatment group had more episodes (<i>p</i> &lt; 0.001) and severe symptoms (PANSS, <i>p</i> &lt; 0.001) with lower cognitive (RBANS, <i>p</i> = 0.001) and social functioning scores (PSP, <i>p</i> &lt; 0.001) compared to the discontinuation group. Regression analysis revealed that fewer episodes (<i>β</i> = 2.799, <i>p</i> = 0.018) and lower PANSS negative symptom scores (<i>β</i> = 0.533, <i>p</i> = 0.011) were associated with a greater likelihood of medication discontinuation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The discontinuation group exhibited milder schizophrenia symptoms and higher social functioning than the continuation group. Furthermore, patients with fewer episodes and milder negative symptoms were more likely to discontinue medication.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50310,"journal":{"name":"International Journal of Methods in Psychiatric Research","volume":"35 2","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mpr.70082","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148200698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Happiness Measured by a Single Item: Psychometric Evaluation of the Arabic Version of Fordyce Global Happiness Scale Among University Students and Mothers of Children With Intellectual Disabilities","authors":"Amira Mohammed Ali,&nbsp;Saeed A. Al-Dossary,&nbsp;Feten Fekih-Romdhane,&nbsp;Maha Atout,&nbsp;Abdulnaser Fakhrou,&nbsp;Mohamed M. H. Suliman,&nbsp;Abdalla S. M. Gaballa,&nbsp;Ahmad M. A. Zayed,&nbsp;Souheil Hallit,&nbsp;Carlos Laranjeira","doi":"10.1002/mpr.70079","DOIUrl":"10.1002/mpr.70079","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Aiming to validate the Fordyce Global Happiness Scale in Arabic, this cross-sectional study recruited two convenience Saudi samples of 422 university students and 85 mothers of children with intellectual disabilities.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Among students, a latent variable model was used to examine scale convergent/divergent validity relative to life satisfaction and depressive symptomatology. Scale cutoffs were assessed in the two samples through cluster analyses and ROC analysis. Differences in happiness were evaluated between mothers and students and across student groups of gender, academic degree, and type of study (practical vs. theoretical).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The latent variable model expressed good fit, showing satisfaction with life and positive affect as significant positive predictors of happiness, which was inversely associated with somatic complaints and negative affect. Two-step cluster analysis resulted in a two-cluster solution, which revealed three cutoffs (among students: &lt; 5, 5–8, &gt; 8 and among mothers: &lt; 4, 4–8, &gt; 8), which significantly classified the samples according to the levels of happiness into low/mild, moderate, and high. ROC analysis revealed an optimal cutoff of 4.5 with high sensitivity (100%) and acceptable specificity (74% and 62%) among students and mothers, respectively. The highest and lowest levels of all depressive symptoms were noticed in participants with happiness scores (&lt; 4.5 or &lt; 5) and &gt; 8, respectively. Known-group validity was signaled by lower overall happiness scores in the mother sample relative to university students.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Fordyce Global Happiness Scale captures happiness as a distinct construct, which relates to the cognitive and emotional components of well-being and physical symptoms of psychopathology.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50310,"journal":{"name":"International Journal of Methods in Psychiatric Research","volume":"35 2","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mpr.70079","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148151829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Building a Brief Multidomain Questionnaire for Gambling Dual Disorder: Psychometric Validation and RDoC-Based Dimensional Structure.","authors":"Ignacio Basurte-Villamor, Ismael Gomez-Talal, Pablo Vega, Mana Azizsoltani, Javier Gonzalez-Peñas, Francisco Ferre, Nestor Szerman","doi":"10.1002/mpr.70078","DOIUrl":"10.1002/mpr.70078","url":null,"abstract":"<p><strong>Objectives: </strong>Gambling Disorder (GD) frequently co-occurs with other mental disorders, a clinical condition termed Gambling Dual Disorder (GDD) that is often overlooked. We aimed to develop and validate a brief multidomain questionnaire to assess GDD severity within a dimensional, transdiagnostic framework.</p><p><strong>Methods: </strong>A 55-item questionnaire was developed and tested across three phases (feasibility, reliability, validity) in 30, 57, and 223 treatment-seeking adults with DSM-5-TR GD. We assessed internal consistency, test-retest reliability, convergent validity against reference instruments (STAI, BDI-II, ISI, BIS, CAARS, SPIN, MULTICAGE-CAD-4, TCI-R, SDI), ROC-derived cutoffs, and the latent dimensional structure via exploratory and confirmatory factor analyses, mapped onto the NIMH Research Domain Criteria (RDoC).</p><p><strong>Results: </strong>Internal consistency was excellent (α = 0.93); test-retest reliability was moderate (ICC = 0.29-0.62). Convergent validity was strong (r ≈ 0.51-0.72). ROC-based cutoffs prioritized sensitivity, with negative predictive values generally above 0.80. A global severity threshold near 1.44 enabled clinical stratification. A four-factor structure emerged: emotional distress and gambling impairment, impulsivity and behavioral activation, social anxiety and interpersonal suspiciousness, and executive dysfunction with negative self-perception.</p><p><strong>Conclusion: </strong>The instrument is a reliable, valid, RDoC-aligned tool for stratifying GDD severity and tailoring integrated interventions.</p>","PeriodicalId":50310,"journal":{"name":"International Journal of Methods in Psychiatric Research","volume":"35 2","pages":"e70078"},"PeriodicalIF":3.4,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13173363/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147934954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric Assessment of the Arabic Translation of the Adult ADHD Self-Report Scale Version 1.1 6-Question Screener.","authors":"Melyssa Assaf, Nelly Kheir, Rabih Hallit, Diana Malaeb, Kamel Jebreen, Fouad Sakr, Mariam Dabbous, Sahar Obeid, Feten Fekih-Romdhane, Souheil Hallit","doi":"10.1002/mpr.70083","DOIUrl":"10.1002/mpr.70083","url":null,"abstract":"<p><strong>Background: </strong>In the Middle East and North Africa, there is a dearth of research on Adult Attention-Deficit/Hyperactivity Disorder (ADHD). Offering a brief, publicly available, and psychometrically valid screening instrument for adult ADHD that can be easily used in large-scale surveys among Arabic-speaking populations could encourage research and facilitate case detection. The purpose of this study was to translate the Adult ADHD Self-Report Scale v1.1 6-Question Screener (ASRS-6) into Arabic and assess its psychometric properties among a sample of Lebanese adults from the general population.</p><p><strong>Methods: </strong>A cross-sectional study was conducted between April and May 2025 using an online survey distributed via a mixed convenience and snowball sampling. A total of 1059 Lebanese adults participated (mean age = 28.52 ± 11.41 years; 66.0% females). The questionnaire included the Arabic ASRS-6, the validated Arabic versions of the Stress Numerical Rating Scale-11, the Patient Health Questionnaire, and the World Health Organization-Five Well-Being Index. The total sample was randomly divided into two split-half subsamples, one for the exploratory (EFA) and the second for the confirmatory (CFA) factor analysis.</p><p><strong>Results: </strong>The EFA and CFA supported the one factor structure, which showed acceptable fit indices. A correlation was added between residuals of items 5 and 6, which improved the model fit and was consequently used in the analysis. A Cronbach's alpha of 0.68 indicated acceptable internal consistency. A significantly higher ASRS-6 mean scores was found in females versus males (10.85 ± 3.98 vs 10.22 ± 4.09; t (1057) = -2.41, p = 0.009, Cohen's d = 0.157). A significantly higher ASRS-6 mean score was found in single participants compared to married ones (10.84 ± 3.95 vs 10.19 ± 4.16; t (1057) = 2.46, p = 0.014, Cohen's d = 0.163). However, no significant difference was found between participants with a secondary level of education or less compared to those with a university education level in terms of ASRS-6 scores (10.20 ± 4.32 vs 10.73 ± 3.95; t (1057) = -1.68, p = 0.094, Cohen's d = 0.131). Higher ASRS-6 scores were significantly associated with higher depression (r = 0.33; p < 0.001), anxiety (r = 0.33; p < 0.001), stress (r = 0.30; p < 0.001), and lower well-being scores (r = -0.38; p < 0.001).</p><p><strong>Conclusion: </strong>The results provide initial support for applying the Arabic version of the ASRS-6 screener in community epidemiological surveys, clinical outreach, and case-finding initiatives. However, additional work is needed to approve its validity and expand its use in different Arab nations.</p>","PeriodicalId":50310,"journal":{"name":"International Journal of Methods in Psychiatric Research","volume":"35 2","pages":"e70083"},"PeriodicalIF":3.4,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13240305/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148007392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Learning Outcomes That Maximally Differentiate Psychiatric Treatments.","authors":"Eric V Strobl, Semmie Kim","doi":"10.1002/mpr.70074","DOIUrl":"10.1002/mpr.70074","url":null,"abstract":"<p><strong>Objectives: </strong>To develop a statistical method that uncovers clinically meaningful differences between active psychiatric treatments, even when traditional rating scales fail to do so.</p><p><strong>Methods: </strong>We introduce Supervised Varimax (SV), a novel algorithm that transforms individual items from clinical rating scales into a small set of optimized outcomes that maximally differentiate treatments. SV was applied to data from two large, multi-center, randomized controlled trials: CATIE (schizophrenia) and STAR*D (treatment-resistant depression).</p><p><strong>Results: </strong>SV identified significant differential treatment effects that were not evident in the original analyses. In CATIE Phase I, olanzapine was more effective than quetiapine and ziprasidone for hostility, and perphenazine outperformed ziprasidone for emotional dysregulation. In Level 2 of STAR*D, bupropion augmentation was more effective than buspirone augmentation for patients with increased appetite. These findings were validated using post-hoc permutation testing and matched to clinical subgroups using simple, symptom-based rules.</p><p><strong>Conclusions: </strong>SV enables precision psychiatry by optimizing outcome definitions to enhance treatment differentiation in RCTs. This approach provides interpretable, clinically actionable insights using existing trial data, without requiring complex predictive modeling or additional biomarkers.</p><p><strong>Trial registration: </strong>CATIE (NCT00014001), STAR*D (NCT00021528).</p>","PeriodicalId":50310,"journal":{"name":"International Journal of Methods in Psychiatric Research","volume":"35 2","pages":"e70074"},"PeriodicalIF":3.4,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13108915/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147787853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating the Mystical Experience Questionnaire Into a Broader Psychometric Framework: English Validation of the Psychedelic Experience Scale and Comparison of Psilocybin and LSD Sessions Across Two Controlled Settings.","authors":"Kurt Stocker, Matthias Hartmann, Frederick S Barrett, William A Richards, Nathan D Sepeda, Laura Ley, Anna M Becker, Friederike Holze, Matthias E Liechti","doi":"10.1002/mpr.70073","DOIUrl":"10.1002/mpr.70073","url":null,"abstract":"<p><strong>Objectives: </strong>For English, the validated part of Psychedelic Experience Scale (PES48) is a four-factor structure called the Mystical Experience Questionnaire (MEQ30). The other validated part of the PES48 consists of four more factors: two more mystical factors (paradoxicality and connectedness, which together with the MEQ30 form the MEQ40), and two more non-mystical factors (visual experience and distressing experience). However, this latter four-factor part of the PES48 has thus far only been validated for the German version of the PES48. We investigated whether the overall eight-factor structure of the PES48 (which includes the MEQ30 four-factor structure) can also be validated, and thus potentially be put to good use in English.</p><p><strong>Methods: </strong>Data from 280 English PES measurements (145 different healthy participants) from four placebo-controlled studies with low to high doses of psilocybin were included. The reliability of the eight subscales was evaluated using measures of internal consistency. The validity of the factor structure was assessed through model fit indices from confirmatory factor analysis. English results were then also compared with the German PES validation data set from Stocker et al. (2024).</p><p><strong>Results: </strong>Six of the eight subscales (mystical, positive mood, transcendence of time and space, ineffability, connectedness, distressing experience) of the English PES48 show high internal consistency, one subscale (paradoxicality) shows good, and one (visual experience) acceptable internal consistency. Both MEQ models (MEQ30 and MEQ40) show similar fits (acceptable to good model fits). In English, both MEQ models show better fits than in German. All six MEQ40 scale means of the English data are higher compared to German data.</p><p><strong>Conclusions: </strong>The findings suggest that the eight-factor PES48 is also a valid psychometric tool in English. With the MEQ40 part of the PES48, one can measure mystical experience with a still wider conceptual breath than with the MEQ30. Furthermore, one can also measure non-mystical visual and distressing states in an overall more comprehensive and broader conceptualization of the psychedelic experience. Higher MEQ40 scale means for the English than the German study participants could inspire future research into the role of setting in relation to mystical experience.</p>","PeriodicalId":50310,"journal":{"name":"International Journal of Methods in Psychiatric Research","volume":"35 2","pages":"e70073"},"PeriodicalIF":3.4,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13110837/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147787898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Suicide Risk Among Transgender Adolescents and Young Adults: A Meta-Analysis of Nearly One Million Participants.","authors":"Noheir Ashraf Ibrahem Fathy Hassan, Eman A Toraih, Menna A Shebl, Amaan Usmani, Uday Atwal, Ayesha Laraib-Ijaz, Helen A O Samuel, Ahmed Ibrahim Eldessouky, Anwar Alhouli, Yusuf Elsawah, Sonnet Sunny, Muaaz Aslam, Jaafer Shah, Yusef Hazimeh, Hani Aiash","doi":"10.1002/mpr.70077","DOIUrl":"10.1002/mpr.70077","url":null,"abstract":"<p><strong>Background: </strong>Mental health disparities among transgender and gender diverse adolescents and young adults represent a critical public health concern. This meta-analysis examined suicidal risk among transgender youth compared to their cisgender peers.</p><p><strong>Methods: </strong>Following PRISMA guidelines, we analyzed 29 studies published between 2015-2024, comprising nearly one million participants (957,163; 29,041 transgender and 928,122 cisgender). Random effects models were used to calculate risk ratios (RR) and prevalence estimates for suicidal ideation, planning, attempts, and completion.</p><p><strong>Results: </strong>Transgender youth showed significantly higher prevalence of suicidal ideation (transmale: 52.2%, transfemale: 49.5% vs. cismale: 18.1%, cisfemale: 22.4%; p < 0.001) and attempts (48.0%-51.3% vs. 18.0%-22.0%; p < 0.001). Risk analyses revealed elevated risks for ideation (RR = 2.38, 95% CI: 1.97-2.88), attempts (RR = 2.85, 95% CI: 1.31-6.21), and completed suicide (RR = 4.80, 95% CI: 2.15-10.74). However, substantial heterogeneity was observed across all suicide outcomes (I² > 90%), indicating that pooled estimates should be interpreted with caution. Publication bias assessment suggested potential overestimation of unadjusted effects, with trim-and-fill adjustment reducing the pooled risk estimate (adjusted RR = 1.25, 95% CI: 1.08-1.45). No significant differences emerged between transmale and transfemale groups (p > 0.05).</p><p><strong>Conclusion: </strong>Overall, this meta-analysis documents markedly elevated suicidality among transgender adolescents and young adults, while emphasizing the need for cautious interpretation of aggregated effect sizes and further high-quality longitudinal research.</p>","PeriodicalId":50310,"journal":{"name":"International Journal of Methods in Psychiatric Research","volume":"35 2","pages":"e70077"},"PeriodicalIF":3.4,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13240427/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148018795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High Prevalences of Current Mental Disorder Diagnoses Among University Students in Sweden: A Cross-Sectional Study With Implications for Student Mental Health Services.","authors":"Anne H Berman, Claes Andersson, Marcus Bendtsen, Petra Lindfors, Nooshin Talebizadeh, Naira Topooco, Olof Molander","doi":"10.1002/mpr.70080","DOIUrl":"10.1002/mpr.70080","url":null,"abstract":"<p><strong>Objectives: </strong>To establish diagnostic prevalences for common mental disorders among students at higher education institutions (HEI's) in Sweden.</p><p><strong>Methods: </strong>This was a cross-sectional study assessing diagnostic prevalences for 17,948 students at 30-day, 12-month and lifetime timepoints, according to the Diagnostic and Statistical Manual, fifth edition (DSM-5). Sample participants at 15 HEI's answered an online survey 2020-2023 within the World Mental Health International College Student (WMH-ICS) initiative. Diagnoses are reported for Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD), Panic Disorder (PD), Bipolar Disorder (BD, any), Alcohol Use Disorder (AUD) and Substance Use Disorder (SUD). Multilevel logistic regression was used to estimate odds ratios in relation to diagnoses of any mental disorder.</p><p><strong>Results: </strong>Respondents (69.4% women, 25.5 mean age, range 18 to ≥ 36) reported 25.2%, 39.3% and 44.5% prevalences for any mental disorder at 30-day, 12-month and lifetime periods. Odds for any mental disorder were markedly higher for non-binary students and those with non-heterosexual orientation; odds were also higher for students aged 20-29 years, women, heterosexual individuals with same-sex attraction and post-pandemic respondents.</p><p><strong>Conclusions: </strong>The findings augment existing concern over student mental health. Student mental health services should expand menus for low-threshold treatment interventions, to promote flourishing and resilience.</p>","PeriodicalId":50310,"journal":{"name":"International Journal of Methods in Psychiatric Research","volume":"35 2","pages":"e70080"},"PeriodicalIF":3.4,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13240059/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148037275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric Validity of the CES-D Scale for Assessing Depressive Symptoms in University Students in Bogotá. Colombia.","authors":"Angela Gissette Caro-Delgado, Víctor Rivera Mancilla, Jorge Medina-Parra, Freddy H Villalobos-Galvis","doi":"10.1002/mpr.70072","DOIUrl":"10.1002/mpr.70072","url":null,"abstract":"<p><strong>Introduction: </strong>The Center for Epidemiological Studies Depression Scale (CES-D) is a widely used tool for assessing depressive symptoms. This study examined its psychometric properties in a sample of 1738 university students in Bogotá.</p><p><strong>Methods: </strong>Instrumental study with a cross-sectional, single-center design with two-stage sampling. Exploratory and two-factor factorial analyses were applied, along with reliability estimates and subgroup analyses by gender and social stratum.</p><p><strong>Results: </strong>Exploratory factor analysis revealed a three-factor structure (depressive affect, positive affect, and social aspects), which explained 56% of the total variance. The KMO index was 0.95, and Bartlett's sphericity test was significant (χ² = 17,902.82, df = 190, p < 0.001). The bifactor model showed a strong overall factor (hierarchical omega = 0.85; ECV = 0.71), supporting the use of a total score. Internal consistency was high (α = 0.93; ω = 0.94). Women scored significantly higher than men (p < 0.001). Differentiated cut-off points by sex are proposed: ≥ 52 for women and ≥ 45 for men.</p><p><strong>Conclusions: </strong>These findings support the validity and reliability of the CES-D as a unidimensional measure of depressive symptoms in the Colombian university population and highlight its usefulness as a screening tool in public health settings, particularly within Latin American regional contexts where early detection of mental health problems is a priority.</p>","PeriodicalId":50310,"journal":{"name":"International Journal of Methods in Psychiatric Research","volume":"35 2","pages":"e70072"},"PeriodicalIF":3.4,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13110790/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147787864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}