A prediction model for differential resilience to the effects of combat-related stressors in US army soldiers

IF 2.4 3区 医学 Q2 PSYCHIATRY
Ronald C. Kessler, Robert M. Bossarte, Irving Hwang, Alex Luedtke, James A. Naifeh, Matthew K. Nock, Maria Petukhova, Ekaterina Sadikova, Nancy A. Sampson, Erik Sverdrup, Jose R. Zubizarreta, Stefan Wager, James Wagner, Murray B. Stein, Robert J. Ursano
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Abstract

Objectives

To develop a composite score for differential resilience to effects of combat-related stressors (CRS) on persistent DSM-IV post-traumatic stress disorder (PTSD) among US Army combat arms soldiers using survey data collected before deployment.

Methods

A sample of n = 2542 US Army combat arms soldiers completed a survey shortly before deployment to Afghanistan and then again two to three and 8–9 months after redeployment. Retrospective self-reports were obtained about CRS. Precision treatment methods were used to determine whether differential resilience to persistent PTSD in the follow-up surveys could be developed from pre-deployment survey data in a 60% training sample and validated in a 40% test sample.

Results

40.8% of respondents experienced high CRS and 5.4% developed persistent PTSD. Significant test sample heterogeneity was found in resilience (t = 2.1, p = 0.032), with average treatment effect (ATE) of high CRS in the 20% least resilient soldiers of 17.1% (SE = 5.5%) compared to ATE = 3.8% (SE = 1.2%) in the remaining 80%. The most important predictors involved recent and lifetime pre-deployment distress disorders.

Conclusions

A reliable pre-deployment resilience score can be constructed to predict variation in the effects of high CRS on persistent PTSD among combat arms soldiers. Such a score could be used to target preventive interventions to reduce PTSD or other resilience-related outcomes.

Abstract Image

美军士兵对作战相关压力影响的不同适应力预测模型。
目标:利用部署前收集的调查数据,为美国陆军作战部队士兵对作战相关压力源(CRS)对持续性 DSM-IV 创伤后应激障碍(PTSD)影响的不同复原力进行综合评分:方法:2542 名美国陆军作战部队士兵在被派往阿富汗前不久完成了一项调查,并在重新部署后两到三个月和 8-9 个月再次完成了调查。调查获得了关于 CRS 的回顾性自我报告。我们采用了精确治疗方法,以确定在后续调查中是否可以从部署前调查数据中发展出对持续性创伤后应激障碍的不同复原力,这些数据来自 60% 的培训样本,并在 40% 的测试样本中得到验证:结果:40.8% 的受访者经历了严重的 CRS,5.4% 的受访者患上了持续性创伤后应激障碍。在复原力方面发现了显著的测试样本异质性(t = 2.1,p = 0.032),在复原力最差的 20% 士兵中,高 CRS 的平均治疗效果(ATE)为 17.1%(SE = 5.5%),而在其余 80% 的士兵中,ATE = 3.8%(SE = 1.2%)。最重要的预测因素涉及近期和终生的部署前困扰障碍:结论:可以构建一个可靠的部署前复原力评分来预测高 CRS 对作战部队士兵中持续性创伤后应激障碍影响的变化。这种评分可用于有针对性的预防干预,以减少创伤后应激障碍或其他与复原力相关的结果。
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来源期刊
CiteScore
5.20
自引率
6.50%
发文量
48
审稿时长
>12 weeks
期刊介绍: The International Journal of Methods in Psychiatric Research (MPR) publishes high-standard original research of a technical, methodological, experimental and clinical nature, contributing to the theory, methodology, practice and evaluation of mental and behavioural disorders. The journal targets in particular detailed methodological and design papers from major national and international multicentre studies. There is a close working relationship with the US National Institute of Mental Health, the World Health Organisation (WHO) Diagnostic Instruments Committees, as well as several other European and international organisations. MPR aims to publish rapidly articles of highest methodological quality in such areas as epidemiology, biostatistics, generics, psychopharmacology, psychology and the neurosciences. Articles informing about innovative and critical methodological, statistical and clinical issues, including nosology, can be submitted as regular papers and brief reports. Reviews are only occasionally accepted. MPR seeks to monitor, discuss, influence and improve the standards of mental health and behavioral neuroscience research by providing a platform for rapid publication of outstanding contributions. As a quarterly journal MPR is a major source of information and ideas and is an important medium for students, clinicians and researchers in psychiatry, clinical psychology, epidemiology and the allied disciplines in the mental health field.
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