Journal of Aapos最新文献_第4页

Intravenous fluorescein overdose in a child undergoing fluorescein angiography 一名接受荧光素血管造影术的儿童静脉注射荧光素过量。

IF 1.2 4区医学

Journal of Aapos Pub Date : 2024-10-01 DOI: 10.1016/j.jaapos.2024.103996

Rhea W. Teng BS, Michael T.B. Nguyen MD, David G. Hunter MD, PhD, Pablo Altschwager MD

引用次数: 0

Fluoxetine as a possible treatment for adult amblyopia: results of a double-blind, randomized, placebo-controlled trial 氟西汀作为治疗成人弱视的一种可能方法：一项双盲、随机、安慰剂对照试验的结果。

IF 1.2 4区医学

Journal of Aapos Pub Date : 2024-10-01 DOI: 10.1016/j.jaapos.2024.104009

Arash Mirmohammadsadeghi MD , Alireza Mousavi MD , Mohammad Reza Akbari MD , Hassan Khojasteh MD , Babak Masoomian MD , Motahhareh Sadeghi MD , Samira Yadegari MD , Hassan Asadigandomani MD

{"title":"Fluoxetine as a possible treatment for adult amblyopia: results of a double-blind, randomized, placebo-controlled trial","authors":"Arash Mirmohammadsadeghi MD , Alireza Mousavi MD , Mohammad Reza Akbari MD , Hassan Khojasteh MD , Babak Masoomian MD , Motahhareh Sadeghi MD , Samira Yadegari MD , Hassan Asadigandomani MD","doi":"10.1016/j.jaapos.2024.104009","DOIUrl":"10.1016/j.jaapos.2024.104009","url":null,"abstract":"<div><h3>Purpose</h3><div>To evaluate the effects of oral fluoxetine on visual acuity and visual-evoked potential (VEP) parameters in adults patching for amblyopia.</div></div><div><h3>Methods</h3><div>In this randomized clinical trial, adults (>18 years of age) with anisometropic or strabismic amblyopia were assigned randomly to a treatment (fluoxetine) group or a placebo group. Standard treatments for amblyopia (glasses prescription and patching) were prescribed for 4 months for all patients beforehand. The first group received fluoxetine (20 mg per day) and the second group received a placebo for 3 months, both continuing patching. Visual acuity evaluation and VEP were performed before and after treatment.</div></div><div><h3>Results</h3><div>A total of 55 participants were included: 29 in the fluoxetine group and 26 in the placebo group. Mean age was 27.2 ± 8.6 years (18-54). The mean logMAR visual acuity of the amblyopic eye improved by 0.20 ± 0.24 (0-0.8) in the fluoxetine group (<em>P</em> < 0.001) and by 0.08 ± 0.15 (0-0.7) in the placebo group (<em>P</em> = 0.01); mean logMAR improvement was significantly higher in the fluoxetine group than in the placebo group (<em>P</em> = 0.04). At the end of the study, mean visual acuity of the fluoxetine group (0.36 ± 0.21 log MAR) was better than the placebo group (0.43 ± 0.35 log MAR). Among the VEP parameters, N75 amplitude did not change significantly in either group relative to baseline, but the changes were statistically significantly different between the two groups (<em>P</em> = 0.05); N135 latency improved from baseline in the fluoxetine group (<em>P</em> = 0.03).</div></div><div><h3>Conclusions</h3><div>In our study cohort, fluoxetine treatment resulted in greater improvement in visual acuity than placebo during patching for adult amblyopia.</div></div>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142299927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preventable vision loss in children with Coats disease 柯茨病儿童可预防的视力丧失。

IF 1.2 4区医学

Journal of Aapos Pub Date : 2024-10-01 DOI: 10.1016/j.jaapos.2024.104000

Francisco Altamirano MD, Efren Gonzalez MD, Ankoor S. Shah MD, PhD, Isdin Oke MD, MPH

{"title":"Preventable vision loss in children with Coats disease","authors":"Francisco Altamirano MD, Efren Gonzalez MD, Ankoor S. Shah MD, PhD, Isdin Oke MD, MPH","doi":"10.1016/j.jaapos.2024.104000","DOIUrl":"10.1016/j.jaapos.2024.104000","url":null,"abstract":"<div><h3>Purpose</h3><div>To describe the prevalence and risk factors associated with amblyogenic refractive error in children with Coats disease.</div></div><div><h3>Methods</h3><div>The medical records of children (<18 years of age) with unilateral Coats disease treated at a single tertiary care center were retrospectively reviewed. Data collected included patient demographics, ocular examinations, and treatments. Outcomes included the prevalence and factors associated with amblyogenic refractive error.</div></div><div><h3>Results</h3><div>A total of 50 children (82% male) were included; of these, 37 (74%) had refractive data to review. The median age at presentation was 5 years (IQR, 2-10). The Coats disease classification was stage 1 in 1 (2%), stage 2 in 29 (58%), and stage 3 or greater in 20 (40%). Most children (76%) had at least one visit with a pediatric specialist; the rest were only seen by a retina specialist. Among patients with refractive data, amblyogenic refractive error was identified in 46%. Glasses were prescribed to 50% of children. Children diagnosed at an earlier age had increased odds of amblyogenic refractive error (OR = 0.72; 95% CI, 0.57-0.91; <em>P</em> = 0.006) than those diagnosed at an older age.</div></div><div><h3>Conclusions</h3><div>Our results suggest that amblyogenic refractive error is prevalent among children with Coats disease, and refractions are not always performed. There is a need to coordinate care between pediatric and retina specialists caring for children with Coats disease to ensure timely diagnosis of amblyogenic refractive error to optimize visual outcomes in this population.</div></div>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142299948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Congenital glaucoma in brittle cornea syndrome type 2 with a novel mutation in PRDM5 脆性角膜综合征 2 型先天性青光眼伴有 PRDM5 的新型突变。

IF 1.2 4区医学

Journal of Aapos Pub Date : 2024-10-01 DOI: 10.1016/j.jaapos.2024.104001

Rashmi Krishnamurthy DNB , Sirisha Senthil FRCS , Jeyapoorani Balasubramanian PhD , Muralidhar Ramappa MD

引用次数: 0

Incidence and presenting clinical features of pediatric keratoconus in a US population 美国儿童角膜病的发病率和临床表现特征。

IF 1.2 4区医学

Journal of Aapos Pub Date : 2024-10-01 DOI: 10.1016/j.jaapos.2024.104003

Marybeth K. Farazdaghi MD , Erick D. Bothun MD , Meagan Tran , David O. Hodge MS , Brian G. Mohney MD

{"title":"Incidence and presenting clinical features of pediatric keratoconus in a US population","authors":"Marybeth K. Farazdaghi MD , Erick D. Bothun MD , Meagan Tran , David O. Hodge MS , Brian G. Mohney MD","doi":"10.1016/j.jaapos.2024.104003","DOIUrl":"10.1016/j.jaapos.2024.104003","url":null,"abstract":"<div><h3>Purpose</h3><div>To report both the incidence of pediatric keratoconus (PKC) in a population-based cohort and the risk for undergoing corneal surgery over a 20-year period at a single institution.</div></div><div><h3>Methods</h3><div>The medical records of all patients <19 years of age diagnosed with keratoconus while residing in Olmsted County, Minnesota, from January 1, 1975, through December 31, 2019, were retrospectively reviewed. The records of patients <19 years with keratoconus examined at our institution from January 1, 2001, through December 31, 2020, were also reviewed.</div></div><div><h3>Results</h3><div>The incidence of PKC in this population over the 45-year study period was 2.48 cases per 100,000 people per year (95% CI, 1.67-3.29). The mean age at diagnosis was 15.25 years (range, 7-18) years, and 28 (77.8%) were male. During a mean follow-up of 2.8 years (range, 0-17.3 years), 33 of 71 patients managed at our institution (46%) underwent at least one corneal procedure. In this cohort, the Kaplan-Meier risk of requiring a procedure by 10 years following diagnosis was 60%.</div></div><div><h3>Conclusions</h3><div>The incidence of PKC in Olmsted County, Minnesota, over a 45-year period was 2.48 cases per 100,000 people per year. Nearly half of the patients managed at our institution over the past 20 years required a procedure during follow-up.</div></div>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142299930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bilateral cataract surgery in children: immediate sequential versus delayed sequential surgery 儿童双侧白内障手术：立即顺序手术与延迟顺序手术。

IF 1.2 4区医学

Journal of Aapos Pub Date : 2024-10-01 DOI: 10.1016/j.jaapos.2024.103992

Helen Wondem MD , Sheldon Stohl MD , Zoma Tede MD , Hadas Mechoulam MD , Irene Anteby MD

{"title":"Bilateral cataract surgery in children: immediate sequential versus delayed sequential surgery","authors":"Helen Wondem MD , Sheldon Stohl MD , Zoma Tede MD , Hadas Mechoulam MD , Irene Anteby MD","doi":"10.1016/j.jaapos.2024.103992","DOIUrl":"10.1016/j.jaapos.2024.103992","url":null,"abstract":"<div><h3>Purpose</h3><div>To compare ocular and anesthesia-related complications in a cohort of patients having undergone either delayed sequential bilateral cataract surgery (DSBCS) or immediate sequential bilateral cataract surgery (ISBCS).</div></div><div><h3>Methods</h3><div>The medical records of children who underwent bilateral cataract surgery at our institution between 2012 and 2021were reviewed retrospectively. Included patients were 0-24 months of age, aphakic, and followed for at least 1 year after surgery.</div></div><div><h3>Results</h3><div>A total of 56 children were included: 23 underwent ISBCS; 33, DSBCS. Mean age at surgery was 2.6 ± 2.5 months for ISBCS patients and 2.8 ± 3.0 months for DSBCS patients (<em>P</em> = 0.752). Association with systemic diseases was more common in the ISBCS group. The mean anesthesia time per child was shorter in the ISBCS group (<em>P</em> < 0.001), although the mean total procedure time was similar in both groups. The rate of intraoperative anesthesia-related complications and intraocular complications was similar in both groups. There were no cases of endophthalmitis. The mean number of additional surgical interventions per child and the mean number of follow-up visits within 1 year were similar between groups. Children in the ISBCS group required fewer nights of hospital admission (<em>P</em> < 0.001).</div></div><div><h3>Conclusions</h3><div>ISBCS in children in this series did not lead to an increased incidence of ocular or anesthesia-related complications compared with DSBCS. ISBCS avoids repeated anesthesia and shortens the total time that the child is under anesthesia.</div></div>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142299924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transient eye closure and ocular preference in patients with intermittent exotropia. 间歇性外斜患者的一过性闭眼和眼球偏好。

IF 1.2 4区医学

Journal of Aapos Pub Date : 2024-09-26 DOI: 10.1016/j.jaapos.2024.104015

Masoud Rostami, Mohammad Yaser Kiarudi, Samira Hassanzadeh, Mohammad Etezad Razavi, Mahdi Sharifi, Mohammed Ziaei

{"title":"Transient eye closure and ocular preference in patients with intermittent exotropia.","authors":"Masoud Rostami, Mohammad Yaser Kiarudi, Samira Hassanzadeh, Mohammad Etezad Razavi, Mahdi Sharifi, Mohammed Ziaei","doi":"10.1016/j.jaapos.2024.104015","DOIUrl":"10.1016/j.jaapos.2024.104015","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the relationship of sensory and motor ocular dominance to transient eye closure (TEC) under bright light conditions in patients with intermittent exotropia.</p><p><strong>Methods: </strong>Forty patients (age range, 7-40 years) with intermittent exotropia were included in this prospective study. Motor and sensory ocular dominance were evaluated using the hole-in-the-card and Worth 4-Dot tests. Presence of any outward eye deviation or TEC was assessed and recorded in all participants under bright light conditions. Based on the fusion control grade of exodeviation, patients were assigned to good, fair, and poor control groups, and the results were compared.</p><p><strong>Results: </strong>A total of 23 patients (58%) showed TEC under bright light: 18 (45%) in the good control group, 14 (35%) in the fair control group, and 8 (20%) in the poor control group. Eighteen patients (56%) with good and fair control showed TEC in the dominant eye. Five (63%) with poor control closed their nondominant eyes, and in all of them, outward eye deviation was observed before TEC. The angle of deviation at far and near and the degree of near stereopsis were not related to presence of TEC (P = 0.70, P = 0.06, and P = 0.34, resp.).</p><p><strong>Conclusions: </strong>In patients with intermittent exotropia who exhibit TEC under bright light, those with good control tend to close the dominant eye, whereas in the majority of patients with poor control, spontaneous deviation occurs and is then followed by TEC of the nondominant eye.</p>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142331573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

US youth perspectives on eye trauma and eye protection 美国青少年对眼外伤和护眼的看法。

IF 1.2 4区医学

Journal of Aapos Pub Date : 2024-08-01 DOI: 10.1016/j.jaapos.2024.103949

{"title":"US youth perspectives on eye trauma and eye protection","authors":"","doi":"10.1016/j.jaapos.2024.103949","DOIUrl":"10.1016/j.jaapos.2024.103949","url":null,"abstract":"<div><p>Eye injuries from sports, activities, and work are a leading cause of vision loss<span> in youth. Most eye injuries can be prevented with protective eyewear. An open-ended survey on youth perspectives on eye trauma and protection was administered to the MyVoice Text Message Cohort of US youth ages 14-24 years. Qualitative, text message responses were coded using thematic analysis. The survey was distributed to 798 recipients; 641 (80.3%) responded. Many youth were concerned about the impact of excessive screen use (n = 278 [43.8%]) and sunlight or UV exposure (n = 239 [37.6%]) on their eye health. Fewer were concerned about injury<span><span> from sports and activities (n = 115 [18.1%]) or job-related eye risks (n = 77 [12.1%]). The most common actions that youth took to protect their eyes included sun protection (eg, sunglasses; n = 300 [47.2%]), refractive correction (eg, glasses, contacts; n = 195 [30.7%]) and screen protection (eg, blue light blocking glasses; n = 159 [25.0%]). Fewer wore eye protection for sports or activities (n = 54 [8.5%]) or work (n = 41 [6.5%]). Youth concerns about eye injury from screens and sunlight are misaligned with the main causes of vision loss in this population, suggesting that </span>public health education is needed to promote optimal eye safety.</span></span></p></div>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141312188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Duane syndrome in association with congenital disorder of glycosylation type Ig (ALG12-CDG) 伴有先天性糖基化紊乱 Ig 型（ALG12-CDG）的杜安综合征。

IF 1.2 4区医学

Journal of Aapos Pub Date : 2024-08-01 DOI: 10.1016/j.jaapos.2024.103954

引用次数: 0

Long-term comparison of horizontal rectus surgery with vertical tendon transposition and combined vertical tendon transposition and inferior oblique–weakening in V-pattern exotropia 水平直肌手术与垂直腱转位术以及垂直腱转位术和下斜肌联合减弱术治疗 V 型外斜视的长期比较。

IF 1.2 4区医学

Journal of Aapos Pub Date : 2024-08-01 DOI: 10.1016/j.jaapos.2024.103958

{"title":"Long-term comparison of horizontal rectus surgery with vertical tendon transposition and combined vertical tendon transposition and inferior oblique–weakening in V-pattern exotropia","authors":"","doi":"10.1016/j.jaapos.2024.103958","DOIUrl":"10.1016/j.jaapos.2024.103958","url":null,"abstract":"<div><h3>Purpose</h3><p>To compare the efficacy of bilateral lateral rectus recession with vertical tendon transposition (LRVT) and LRVT combined with inferior oblique (IO) disinsertion for V-pattern exotropia.</p></div><div><h3>Methods</h3><p>The medical records of patients who had mild-to-moderate (+1 and +2) inferior oblique overaction (IOOA) and underwent half-tendon-width upward LRVT (transposition group), and LRVT with IO disinsertion (combined surgery group) for V-pattern exotropia and who had at least 3 years of postoperative follow-up were reviewed retrospectively.</p></div><div><h3>Results</h3><p>A total of 45 patients were included: 22 in the transposition group and 23 in the combined surgery group. Preoperatively, there were no differences in V pattern, IOOA, or horizontal misalignment in primary position, upgaze, or downgaze between groups. The amount of exotropia in the primary position was 30.2<sup>Δ</sup> ± 10.7<sup>Δ</sup> in the transposition group, and 31.6<sup>Δ</sup> ± 14.1<sup>Δ</sup> in the combined surgery group (<em>P</em> = 0.974). A significant decrease in V pattern was observed in the combined surgery group and the transposition group at 6 months and 3 years postoperatively (<em>P</em> < 0.001). The reduction of V pattern in the combined surgery group at 6 months (20.2<sup>Δ</sup> ± 7.8<sup>Δ</sup> vs 15.6<sup>Δ</sup> ± 6.9<sup>Δ</sup> [<em>P</em> = 0.02]) and 3 years (20.1<sup>Δ</sup> ± 8.1<sup>Δ</sup> vs 15.2<sup>Δ</sup> ± 7.1<sup>Δ</sup> [<em>P</em> = 0.014]) was found to be greater than the transposition group. There were no differences in the success rate in the primary position at 6 months (<em>P</em> > 0.05).</p></div><div><h3>Conclusions</h3><p>Both tendon transposition with horizontal rectus surgery and combined tendon transposition and IO-weakening surgery decreased V-pattern exotropia. However, combined surgery had a greater effect on decreasing V pattern in patients with mild-to-moderate IOOA.</p></div>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141472116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0