Jia-Wen Song , Xiao-Yan Huang , Mei Huang , Shi-Han Cui , Yong-Jin Zhou , Xiao-Zheng Liu , Zhi-Han Yan , Xin-Jian Ye , Kun Liu
{"title":"Abnormalities in spontaneous brain activity and functional connectivity are associated with cognitive impairments in children with type 1 diabetes mellitus","authors":"Jia-Wen Song , Xiao-Yan Huang , Mei Huang , Shi-Han Cui , Yong-Jin Zhou , Xiao-Zheng Liu , Zhi-Han Yan , Xin-Jian Ye , Kun Liu","doi":"10.1016/j.neurad.2024.101209","DOIUrl":"10.1016/j.neurad.2024.101209","url":null,"abstract":"<div><h3>Background</h3><p>It remains unclear whether alterations in brain function occur in the early stage of pediatric type 1 diabetes mellitus(T1DM). We aimed to examine changes in spontaneous brain activity and functional connectivity (FC) in children with T1DM using resting-state functional magnetic resonance imaging (rs-fMRI), and to pinpoint potential links between neural changes and cognitive performance.</p></div><div><h3>Methods</h3><p>In this study, 22 T1DM children and 21 age-, sex-matched healthy controls underwent rs-fMRI. The amplitude of low frequency fluctuations (ALFF) and seed-based FC analysis were performed to examine changes in intrinsic brain activity and functional networks in T1DM children. Partial correlation analyses were utilized to explore the correlations between ALFF values and clinical parameters.</p></div><div><h3>Results</h3><p>The ALFF values were significantly lower in the lingual gyrus (LG) and higher in the left medial superior frontal gyrus (MSFG) in T1DM children compared to controls. Subsequent FC analysis indicated that the LG had decreased FC with bilateral inferior occipital gyrus, and the left MSFG had decreased FC with right precentral gyrus, right inferior parietal gyrus and right postcentral gyrus in children with T1DM. The ALFF values of LG were positively correlated with full-scale intelligence quotient and age at disease onset in T1DM children, while the ALFF values of left MSFG were positively correlated with working memory scores.</p></div><div><h3>Conclusion</h3><p>Our findings revealed abnormal spontaneous activity and FC in brain regions related to visual, memory, default mode network, and sensorimotor network in the early stage of T1DM children, which may aid in further understanding the mechanisms underlying T1DM-associated cognitive dysfunction.</p></div>","PeriodicalId":50115,"journal":{"name":"Journal of Neuroradiology","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2024-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141184865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nazanin Azizi, Jimmy L. Huynh, Osama Raslan, Matthew Bobinski, Lotfi Hacein-Bey, Arzu Ozturk
{"title":"Pediatric cervical spine clearance after blunt trauma and negative CT: What is the role of MRI?","authors":"Nazanin Azizi, Jimmy L. Huynh, Osama Raslan, Matthew Bobinski, Lotfi Hacein-Bey, Arzu Ozturk","doi":"10.1016/j.neurad.2024.101206","DOIUrl":"10.1016/j.neurad.2024.101206","url":null,"abstract":"<div><h3>Background and purpose</h3><p>The cervical spine in children has marked anatomical and biomechanical differences compared to adults, leading to significantly different patterns and incidence of spinal injury, and consequently to different X-ray and computed tomography (CT) imaging recommendations. Magnetic resonance imaging (MRI) has been validated to clear cervical spine trauma in adults, but not in pediatric patients. We hypothesized that MRI findings have a low probability to change management in children with spine trauma and negative CT findings.</p></div><div><h3>Materials and methods</h3><p>We reviewed records for admitted pediatric patients due to blunt trauma from January 2011 to May 2021, and identified 212 patients who underwent MRI within 3 days of a negative CT. Two neuroradiologists independently reviewed all CT and MRI images for the following categories: fracture, subluxation, spinal canal compromise, ligamentous injury, spinal canal hemorrhage, cord contusion and soft tissue hemorrhage. We identified follow-up MRI examinations as negative or positive for the above categories, and calculated the prevalence of each category as a percentage of cases with negative CT. We also evaluated whether negative and positive MRI groups differed significantly with respect to age and sex of the patients.</p></div><div><h3>Results and conclusions</h3><p>In our study of 212 children with cervical spine trauma and a negative CT, most follow-up MRI scans were found to be negative (79.9 %). Positive MRI findings consisted mainly of ligamentous sprain without disruption (15.1 %). Ligamentous disruption and epidural or soft tissue hemorrhage were found in 4.5 %, and focal cord contusion in 0.5 %. There was no statically significant difference between negative and positive MRI groups with respect to age (<em>P</em> = 0.45) and sex (<em>P</em> = 0.52).</p></div><div><h3>Conclusion</h3><p>In our patient group with a negative CT, MRI did not significantly impact management nor contribute to cervical spine clearance in children.</p></div>","PeriodicalId":50115,"journal":{"name":"Journal of Neuroradiology","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2024-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141159032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Let's find out about Article-Based Publishing (ABP)/Article Numbering (AN)","authors":"Douraied Ben Salem","doi":"10.1016/j.neurad.2024.101198","DOIUrl":"https://doi.org/10.1016/j.neurad.2024.101198","url":null,"abstract":"","PeriodicalId":50115,"journal":{"name":"Journal of Neuroradiology","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141094912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Meditation mindfulness and hypnosis: We know they work, but just how do they work?","authors":"Lotfi Hacein-Bey, Sidney Krystal, Jean-Pierre Pruvo","doi":"10.1016/j.neurad.2024.101199","DOIUrl":"https://doi.org/10.1016/j.neurad.2024.101199","url":null,"abstract":"","PeriodicalId":50115,"journal":{"name":"Journal of Neuroradiology","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2024-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140950822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A call for junior neuroradiologists to join the “Jeunes Enthousiastes en neuroradiologie DIagnostique” - Research Collaboration (JEDI-RC)","authors":"Thomas Samoyeau","doi":"10.1016/j.neurad.2024.04.003","DOIUrl":"https://doi.org/10.1016/j.neurad.2024.04.003","url":null,"abstract":"","PeriodicalId":50115,"journal":{"name":"Journal of Neuroradiology","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140813541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The importance of arterial systolic pressure (Push) in successful first pass aspiration technique for endovascular thrombectomy","authors":"D Volders, V Linehan, IR Macdonald","doi":"10.1016/j.neurad.2024.04.004","DOIUrl":"10.1016/j.neurad.2024.04.004","url":null,"abstract":"","PeriodicalId":50115,"journal":{"name":"Journal of Neuroradiology","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2024-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140854249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Guillaume Charbonnier, Fortunato Di Caterino, Alessandra Biondi
{"title":"Reply to “Successful recanalization because of the pressure differential between arterial systolic pressure (Push) and vacuum level created by the vacuum source (Pull)”","authors":"Guillaume Charbonnier, Fortunato Di Caterino, Alessandra Biondi","doi":"10.1016/j.neurad.2024.04.005","DOIUrl":"10.1016/j.neurad.2024.04.005","url":null,"abstract":"","PeriodicalId":50115,"journal":{"name":"Journal of Neuroradiology","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2024-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140871030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Factors related to vessel displacement due to stent retriever retraction: An in vitro study","authors":"Hiroyuki Ikeda, Masanori Kinosada, Minami Uezato, Yoshitaka Kurosaki, Masaki Chin, Sen Yamagata","doi":"10.1016/j.neurad.2024.04.002","DOIUrl":"10.1016/j.neurad.2024.04.002","url":null,"abstract":"<div><h3>Background</h3><p>Thrombectomy with a stent retriever (SR) may lead to intracranial hemorrhage due to vessel displacement. We aimed to explore factors related to vessel displacement using an in vitro vessel model.</p></div><div><h3>Methods</h3><p>A vessel model mimicking two-dimensional left internal carotid angiography findings was used in this study. Six SR types (Solitaire 3 × 40, 4 × 40, and 6 × 40; Embotrap 5 × 37; Trevo 4 × 41; and Tron 4 × 40) were fully deployed in the M2 ascending, M2 bend, or M1 horizontal portion. Subsequently, the SR was retracted, and the vessel displacement, maximum SR retraction force, and angle of the M2 bend portion were measured. A total of 180 SR retraction experiments were conducted using 6 SR types at 3 deployment positions with 10 repetitions each.</p></div><div><h3>Results</h3><p>The mean maximum distance of vessel displacement for Embotrap Ⅲ 5 × 37 (6.4 ± 3.5 mm, <em>n</em> = 30) was significantly longer than that for the other five SR types (<em>p</em> = 0.029 for Solitaire 6 × 40 and <em>p</em> < 0.001 for the others, respectively). Vessel displacement was significantly longer in the M2 ascending portion group (5.4 ± 3.0 mm, <em>n</em> = 60) than in the M2 bend portion group (3.3 ± 1.6 mm, <em>n</em> = 60) (<em>p</em> < 0.001) and it was significantly longer in the M2 bend portion group than in the M1 horizontal portion group (1.1 ± 0.7 mm, <em>n</em> = 60) (<em>p</em> < 0.001). A positive correlation existed between the mean maximum SR retraction force or mean angle of the M2 bend portion due to SR retraction (i.e., vessel straightening) and the mean maximum distance of vessel displacement (<em>r</em> = 0.90, <em>p</em> < 0.001; <em>r</em> = 0.90, <em>p</em> < 0.001, respectively).</p></div><div><h3>Conclusions</h3><p>Vessel displacement varied with the SR type, size, and deployment position. Moreover, vessel displacement correlated with the SR retraction force or vessel straightening of the M2 bend portion.</p></div>","PeriodicalId":50115,"journal":{"name":"Journal of Neuroradiology","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2024-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140636404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maëlle Guéganton-Lecat , Romain Provost , Tania Delabarde , Claire Saccardy , Mathilde Ducloyer , Douraied Ben Salem
{"title":"CT analysis of skull contents in naturally mummified human corpses, a multicentric study","authors":"Maëlle Guéganton-Lecat , Romain Provost , Tania Delabarde , Claire Saccardy , Mathilde Ducloyer , Douraied Ben Salem","doi":"10.1016/j.neurad.2024.04.001","DOIUrl":"10.1016/j.neurad.2024.04.001","url":null,"abstract":"<div><h3>Introduction</h3><p>This study aimed to assess skull contents, brain appearance, and density on postmortem computed tomography in naturally mummified corpses.</p></div><div><h3>Material and Methods</h3><p>For this purpose, a retrospective multicentric study, including mummified corpses from two French centers (Brest and Nantes) and from the New Mexico Decedent Image Database (USA), was performed by analyzing postmortem computed tomography (PMCT) focused on the head and neck of partially or fully mummified corpses discovered between 2011 and 2022. The PMCT analysis provided data on the CT appearance of brains, allowing them to be classified into four different categories (desiccation, liquefaction, dura mater only (DMO), and absence), and to measure densities (HU) of the brain remains. In addition, data on postmortem intervals (PMI) from Nantes and Brest centers were collected and analyzed to test the link between brain densities and PMIs.</p></div><div><h3>Results</h3><p>54 cases of naturally mummified corpses were included. The brains were classified as liquefied (56%), desiccated (17 %), DMO (20 %), and absent (7 %) based on their CT appearance. Dehydrated brains were significantly (<em>p</em> < 0.004) denser (median 102 HU, interquartile range (IQR) 41) than either liquefied brains (median 39.5 HU, IQR 9) or brains with DMO (median -25 HU, IQR 57). However, the density of brain remains was not significantly affected by where the bodies were found (<em>p</em> = 0,41). Analysis of PMI and brain densities was performed on 22 cases. The results showed that brain remains were significantly (<em>p</em> = 0.039) denser when they were found after a PMI of more than six months.</p></div><div><h3>Conclusion</h3><p>Brain desiccation was the aspect with the highest densities on PMCT, and for which we were able to highlight great preservation of anatomical structures observable in living organisms.</p></div>","PeriodicalId":50115,"journal":{"name":"Journal of Neuroradiology","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2024-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140636375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lufei Feng , Mengying Yu , Mo Zheng , Wangle Huang , Fei Yao , Chaomin Qiu , Ru Lin , Ying Zhou , Haoyu Wu , Guoquan Cao , Dexing Kong , Yunjun Yang , Haoli Xu
{"title":"Low blood flow ratio is associated with hemorrhagic transformation secondary to mechanical thrombectomy in patients with acute ischemic stroke","authors":"Lufei Feng , Mengying Yu , Mo Zheng , Wangle Huang , Fei Yao , Chaomin Qiu , Ru Lin , Ying Zhou , Haoyu Wu , Guoquan Cao , Dexing Kong , Yunjun Yang , Haoli Xu","doi":"10.1016/j.neurad.2024.03.003","DOIUrl":"10.1016/j.neurad.2024.03.003","url":null,"abstract":"<div><h3>Background and purpose</h3><p>A significant decrease of cerebral blood flow (CBF) is a risk factor for hemorrhagic transformation (HT) in acute ischemic stroke (AIS). This study aimed to ascertain whether the ratio of different CBF thresholds derived from computed tomography perfusion (CTP) is an independent risk factor for HT after mechanical thrombectomy (MT).</p></div><div><h3>Methods</h3><p>A retrospective single center cohort study was conducted on patients with AIS undergoing MT at the First Affiliated Hospital of Wenzhou Medical University from August 2018 to December 2023. The perfusion parameters before thrombectomy were obtained according to CTP automatic processing software. The low blood flow ratio (LFR) was defined as the ratio of brain volume with relative CBF <20 % over volume with relative CBF <30 %. HT was evaluated on the follow-up CT images. Binary logistic regression was used to analyze the correlation between parameters that differ between the two groups with regards to HT occurrence. The predictive efficacy was assessed utilizing the receiver operating characteristic curve.</p></div><div><h3>Results</h3><p>In total, 243 patients met the inclusion criteria. During the follow-up, 46.5 % of the patients (113/243) developed HT. Compared with the Non-HT group, the HT group had a higher LFR (0.47 (0.34–0.65) vs. 0.32 (0.07–0.56); <em>P</em> < 0.001). According to the binary logistic regression analysis, the LFR (aOR: 6.737; 95 % CI: 1.994–22.758; <em>P</em> = 0.002), Hypertension history (aOR: 2.231; 95 % CI: 1.201–4.142; <em>P</em> = 0.011), plasma FIB levels before MT (aOR: 0.641; 95 % CI: 0.456–0.902; <em>P</em> = 0.011), and the mismatch ratio (aOR: 0.990; 95 % CI: 0.980–0.999; <em>P</em> = 0.030) were independently associated with HT secondary to MT. The area under the curve of the regression model for predicting HT was 0.741.</p></div><div><h3>Conclusion</h3><p>LFR, a ratio quantified via CTP, demonstrates potential as an independent risk factor of HT secondary to MT.</p></div>","PeriodicalId":50115,"journal":{"name":"Journal of Neuroradiology","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140584810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}