Journal of Neuroradiology最新文献

{"title":"Increased 18F-FAPI-04 uptake in neurofibromatosis type 1 in a patient with synchronous bilateral breast cancer","authors":"Yuting Wu , Chunxiu Yuan , Dongju Li , Xiaowei Ma , Jiqin Yang","doi":"10.1016/j.neurad.2025.101385","DOIUrl":"10.1016/j.neurad.2025.101385","url":null,"abstract":"","PeriodicalId":50115,"journal":{"name":"Journal of Neuroradiology","volume":"52 6","pages":"Article 101385"},"PeriodicalIF":3.3,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145024639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic value of centrally restricted diffusion in differentiating radiation necrosis from tumor progression in brain metastases: A single-center observational study","authors":"Valentin Laigle ,&nbsp;Laure Thomas ,&nbsp;Thiebaud Picart ,&nbsp;Emanuele Tommasino ,&nbsp;Chloé Dumot ,&nbsp;Anne d’Hombres ,&nbsp;Loïc Feuvret ,&nbsp;Emilien Jupin-Delevaux ,&nbsp;Delphine Gamondès ,&nbsp;Marc Hermier ,&nbsp;François Cotton ,&nbsp;Jérôme Honnorat ,&nbsp;François Ducray ,&nbsp;Yves Berthezène ,&nbsp;Alexandre Bani-Sadr","doi":"10.1016/j.neurad.2025.101386","DOIUrl":"10.1016/j.neurad.2025.101386","url":null,"abstract":"<div><h3>Background</h3><div>Distinguishing radiation necrosis (RN) from true progression (TP) in irradiated brain metastases is challenging. We evaluated the diagnostic performance of the centrally restricted diffusion sign on diffusion-weighted imaging (DWI).</div></div><div><h3>Methods</h3><div>From August 2014 to August 2024, we screened 321 patients with histologically confirmed brain metastases treated with radiation therapy and follow-up MRI for new or enlarging necrotic lesions ≥1 cm. Two board-certified neuroradiologists independently assessed the centrally restricted diffusion sign—central hyperintensity on b1000 images with corresponding ADC reduction—by rigidly co-registering DWI to postcontrast 3D T1-weighted sequences. Quantitative analysis included mean ADC measurement within manually drawn regions of interest in the necrotic core and the contrast-enhancing rim. Final diagnoses were established by histopathology (<em>n</em> = 17) or multidisciplinary consensus (<em>n</em> = 90).</div></div><div><h3>Results</h3><div>Of 107 patients (median age, 62 years; 57.9 % male), 62 had TP and 45 had RN. Median interval from radiotherapy completion to index MRI was 10.8 months. Overall survival was longer in patients with RN (median not reached) than in those with TP (17.5 months; <em>P</em> &lt; 0.0001). Interobserver agreement for the centrally restricted diffusion sign was moderate (κ =0.55). The sign appeared in 34/45 RN cases and 13/62 TP cases (<em>P</em> &lt; 0.0001). For RN diagnosis, sensitivity was 75.6 %, specificity 79.0 %, and accuracy 77.6 %. Quantitative ADC metrics did not enhance performance.</div></div><div><h3>Conclusion</h3><div>The centrally restricted diffusion sign on DWI may aid differentiation of RN from TP in irradiated brain metastases, despite moderate interrater reliability.</div></div>","PeriodicalId":50115,"journal":{"name":"Journal of Neuroradiology","volume":"52 6","pages":"Article 101386"},"PeriodicalIF":3.3,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intraoperative and long-term multimodal radiological assessment of brain MR-guided laser interstitial thermal therapy (MRgLITT) in children","authors":"Alice Hu ,&nbsp;Lelio Guida ,&nbsp;Ludovic Fillon ,&nbsp;Rima Nabbout ,&nbsp;François Doz ,&nbsp;Oumaima Aboubakr ,&nbsp;Thomas Blauwblomme ,&nbsp;Nathalie Boddaert ,&nbsp;Volodia Dangouloff-Ros","doi":"10.1016/j.neurad.2025.101377","DOIUrl":"10.1016/j.neurad.2025.101377","url":null,"abstract":"<div><h3>Objectives</h3><div>Magnetic resonance-guided laser interstitial thermal therapy (MRgLITT) has emerged as a minimally invasive alternative for drug-resistant epilepsy and pediatric brain tumors, particularly in deep-seated lesions where open surgery presents significant risks. However, the multimodal imaging characteristics of lesions during and after MRgLITT remain underexplored. This study aims to describe the MRI features of MRgLITT-treated lesions in pediatric patients both intraoperatively and during long-term follow-up.</div></div><div><h3>Methods</h3><div>We conducted a retrospective analysis of 26 pediatric patients(32 procedures) treated using MRgLITT, including focal cortical dysplasias, low-grade tumors and hamartomas. Imaging acquisition included preoperative, intraoperative, and postoperative MRI with advanced sequences(T1-weighted, FLAIR, DWI, ASL perfusion, and MR spectroscopy). Lesion evolution was assessed over a one-year follow-up period.</div></div><div><h3>Results</h3><div>Intraoperatively, lesions showed a rim of high signal on DWI and on post-contrast T1-weighted images, a lactate peak on MR spectroscopy, and the majority of them had peripheral high signal on FLAIR associated with a low signal core and increased CBF on ASL. During follow-up, lesions may increase in size in the first days or weeks, then decrease in size mainly in the first 3 months and tend to stabilize at 9 months, with persistent gliotic changes on FLAIR sequences. Contrast enhancement resolved in epilepsy-related lesions, but small areas remained in most tumors without correlation with progression.</div></div><div><h3>Conclusion</h3><div>MRgLITT results in a predictable pattern of imaging changes, with lesion contraction occurring primarily within the first 3 months. Understanding these radiological markers is essential for optimizing post-procedure management and treatment decisions in pediatric epilepsies and tumors.</div></div>","PeriodicalId":50115,"journal":{"name":"Journal of Neuroradiology","volume":"52 6","pages":"Article 101377"},"PeriodicalIF":3.3,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144859858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Defining optimal thrombectomy-per-ischemic-stroke targets: a methodology for guiding procedure volumes per center in France","authors":"Fabien de Oliveira ,&nbsp;Lucas Léger ,&nbsp;Chris Serrand ,&nbsp;Vincent Costalat ,&nbsp;Jean-Paul Beregi ,&nbsp;Thibault Mura ,&nbsp;Thierry Boudemaghe ,&nbsp;Julien Frandon","doi":"10.1016/j.neurad.2025.101375","DOIUrl":"10.1016/j.neurad.2025.101375","url":null,"abstract":"<div><h3>Background and purpose</h3><div>Mechanical thrombectomy (MT) has emerged as a groundbreaking treatment for large vessel occlusion strokes. There is limited data on the expected number of thrombectomies based on regional demographics, the ideal proximity to thrombectomy centers for the population, and the appropriate thrombectomy-per-ischemic-stroke ratio centers should target.</div></div><div><h3>Materials and methods</h3><div>This retrospective analysis (2018–2024) used data from the French National Uniform Hospital Discharge Dataset to establish benchmark indicators guiding public health policy. We defined the Thrombectomy Target Level (TTL) as the median standardized thrombectomy-per-ischemic-stroke ratio and the Thrombectomy Alert Level (TAL) as the 25th percentile of the standardized thrombectomy-per-stroke ratio across all administrative regions. These thresholds were calculated annually, and percentages were mapped. Using the TTL and the distribution of thrombectomy-treated stroke cases as a function of distance, we determined the maximum car travel time to achieve this goal.</div></div><div><h3>Results</h3><div>Over the study period, 803,058 strokes and 49,154 thrombectomies (6.1 % of all strokes) were reported in the PMSI. TTL rose from 4.4 % in 2018 to 7.0 % in 2024 and TAL rose from 3.6 % to 5.6 %. The geographic distribution of standardized thrombectomy-per-ischemic-stroke ratio revealed disparities in thrombectomy treatment levels across regions. To meet TTL objectives, the population should be within 50 min by car from a thrombectomy center.</div></div><div><h3>Conclusion</h3><div>We set epidemiological thresholds as targets (TTL) and alerts (TAL) to identify regions performing insufficient thrombectomies. Public health authorities can use these thresholds to adjust and optimize healthcare services. For optimal access, the population should be within an hour’s drive from a center.</div></div>","PeriodicalId":50115,"journal":{"name":"Journal of Neuroradiology","volume":"52 5","pages":"Article 101375"},"PeriodicalIF":3.3,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144827152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"5.0T MRA techniques for evaluating Moyamoya disease: 4D-ASL-MRA vs. 3D-TOF-MRA","authors":"Shi-hai Zhao ,&nbsp;Yuan-ren Zhai ,&nbsp;Yi-jun Zhou ,&nbsp;Gan Sun ,&nbsp;Ke Xue ,&nbsp;Hua-lu Han ,&nbsp;Dong Wang ,&nbsp;Yu-xin Yang ,&nbsp;Ming-li Li ,&nbsp;Jun Ni ,&nbsp;Dong Zhang ,&nbsp;Yi-ning Wang ,&nbsp;Feng Feng","doi":"10.1016/j.neurad.2025.101376","DOIUrl":"10.1016/j.neurad.2025.101376","url":null,"abstract":"<div><h3>Purpose</h3><div>Three-dimensional time-of-flight MR-angiography (3D-TOF-MRA) at 5.0T showed comparable capacity to 7.0T for visualizing small vessels, but has not yet been compared with arterial spin labeling (ASL)-based four-dimensional MR-angiography (4D-ASL-MRA) at 5.0T. This study aimed to compare the performance of these two MRA techniques at 5.0T in evaluating Moyamoya disease (MMD).</div></div><div><h3>Methods</h3><div>This retrospective study included 20 consecutive MMD patients who underwent 4D-ASL-MRA with six labeling times (100 ms to 1800 ms) and 3D-TOF-MRA at 5.0T Analyses included Suzuki grades, contrast-to-noise ratio (CNR), number of branches in middle cerebral artery (MCA), and image scores of terminal internal carotid arteries (ICA), stenosis around terminal ICA, distal MCA, Moyamoya vessels, and leptomeningeal anastomosis (LMA) collateral vessels.</div></div><div><h3>Results</h3><div>Twenty patients (10 females, 33 ± 8 years) with 30 cerebral hemispheres were analyzed. Compared to 3D-TOF-MRA, 4D-ASL-MRA with 900 ms to 1800 ms labeling times demonstrated superior visualization scores for terminal ICA, stenosis around terminal ICA, and LMA (4D-ASL-MRA with 900 ms vs 3D-TOF-MRA: 4.00 ± 0.00 vs 3.50 ± 0.68, 3.00 ± 0.00 vs 2.68 ± 0.55, 2.37 ± 1.19 vs 1.40 ± 0.97, respectively, all <em>p</em> &lt; 0.05), and 4D-ASL-MRA at 1800 ms showed higher CNR in the M4 segment (45.84 ± 20.28 vs 27.54 ± 24.46, <em>p</em> &lt; 0.001) but lower in M1 to M3 segments (65.61 ± 36.22 vs 173.58 ± 148.25, 48.89 ± 29.44 vs 122.86 ± 104.23, 44.68 ± 30.05 vs 78.36 ± 72.64, respectively, all <em>p</em> &lt; 0.05) and more visible distal MCA branches (24.83 ± 5.49 vs 15.03 ± 5.99, <em>p</em> &lt; 0.001). The inter-modality agreement on Suzuki grades between 4D-ASL-MRA and digital subtraction angiography (DSA) was excellent (κ= 0.88), outperforming that between 3D-TOF-MRA and DSA (κ= 0.57).</div></div><div><h3>Conclusion</h3><div>At 5.0T, 4D-ASL-MRA demonstrated superior visualization of terminal ICA, distal MCA, and collateral vessels in MMD, as well as staging MMD more accurately than 3D-TOF-MRA.</div></div>","PeriodicalId":50115,"journal":{"name":"Journal of Neuroradiology","volume":"52 6","pages":"Article 101376"},"PeriodicalIF":3.3,"publicationDate":"2025-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144823116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of MRI as a key evaluator of mesenchymal stem Cell Therapy in Multiple Sclerosis: A systematic review and meta-analysis","authors":"Mohammadreza Elhaie ,&nbsp;Abolfazl Koozari ,&nbsp;Mohammadhossein Mozafari ,&nbsp;Iraj Abedi","doi":"10.1016/j.neurad.2025.101374","DOIUrl":"10.1016/j.neurad.2025.101374","url":null,"abstract":"<div><h3>Background</h3><div>Multiple Sclerosis (MS) is a chronic, immune-mediated disorder marked by inflammation, demyelination, and neurodegeneration, necessitating regenerative therapies. Mesenchymal stem cell (MSC) therapy offers immunomodulatory and neuroprotective potential, but clinical evaluation is challenging.</div></div><div><h3>Methods</h3><div>This systematic review and meta-analysis, registered on PROSPERO (CRD420251017175) and following PRISMA 2020 guidelines, evaluated MRI’s role in assessing MSC therapy for MS. We searched PubMed, Embase, Scopus, Web of Science, and Cochrane Library, screening 1687 records. Nine peer-reviewed clinical studies (<em>n</em> = 7–48 MS patients) were included. MRI modalities (e.g., T1/T2-weighted, diffusion tensor imaging) and outcomes (e.g., lesion load, remyelination) were analyzed narratively and quantitatively using Review Manager 5.1.</div></div><div><h3>Results</h3><div>Conventional MRI detected short-term reductions in lesion load and inflammation, while advanced techniques showed microstructural repair, notably with intrathecal MSCs. An exploratory Meta-analysis of four studies found a significant T2 lesion volume decrease (mean difference -5.12 mm³, 95 % CI -9.65 to -0.59, <em>P</em> = 0.03, I²=93 %) and higher likelihood of no new T2 lesions (risk ratio 1.69, 95 % CI 1.31–2.19, <em>P</em> &lt; 0.0001, I²=0 %). High heterogeneity and small sample sizes limited findings.</div></div><div><h3>Conclusion</h3><div>MRI shows promise as a biomarker for MSC therapy efficacy in MS, capturing lesion dynamics. Larger, standardized trials are needed to address methodological inconsistencies and validate findings. This study uniquely emphasizes the role of MRI—including advanced modalities—as a primary outcome measure for MSC therapy in MS, highlighting gaps in imaging standardization across studies</div></div>","PeriodicalId":50115,"journal":{"name":"Journal of Neuroradiology","volume":"52 5","pages":"Article 101374"},"PeriodicalIF":3.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144704096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Single-stent strategy for a dissected carotid loop in acute tandem occlusion: Technical considerations","authors":"Jean Papaxanthos,&nbsp;Malgorzata Milnerowicz,&nbsp;Xavier Barreau,&nbsp;Omer Eker,&nbsp;Jerome Berge,&nbsp;Gaultier Marnat,&nbsp;Thomas Courret","doi":"10.1016/j.neurad.2025.101373","DOIUrl":"10.1016/j.neurad.2025.101373","url":null,"abstract":"<div>Managing a dissected carotid loop in tandem occlusion stroke is a challenging situation. Despite the low stroke recurrence rate after spontaneous carotid dissection, some situations may require carotid stenting.1, 2, 3 After intracranial revascularization, several complex endovascular techniques have been reported, aiming to adapt to the tortuous anatomy of the carotid and involving extensive metal coverage through telescopic stenting and flow diverters in the acute phase.4, 5, 6 In this video, </div>","PeriodicalId":50115,"journal":{"name":"Journal of Neuroradiology","volume":"52 5","pages":"Article 101373"},"PeriodicalIF":3.0,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144679965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dual antiplatelet therapy practices following Pipeline Shield embolization and their impact on adverse events in three large real-life registries","authors":"Jildaz Caroff ,&nbsp;Cristian Mihalea ,&nbsp;Jens Fiehler ,&nbsp;Mario Martinez-Galdamez ,&nbsp;Saleh Lamin ,&nbsp;Markus Holtmannspötter ,&nbsp;Laurent Spelle","doi":"10.1016/j.neurad.2025.101372","DOIUrl":"10.1016/j.neurad.2025.101372","url":null,"abstract":"<div><h3>Background</h3><div>Dual Antiplatelet Therapy (DAPT) prescription following flow-diverter stent treatment of intracranial aneurysms is standard of care but evidence regarding the drugs of choice and duration of DAPT remains limited. We aim report to report practitioners’ DAPT prescribing habits and to analysis their impact on adverse events in real-world use of Pipeline™ Flex with Shield Technology stent.</div></div><div><h3>Methods</h3><div>Data from 3 post-market core lab adjudicated studies were retrospectively analyzed. Patients with acutely ruptured aneurysms, or on single APT were excluded. DAPT durations were collected, and patients were divided in 2 DAPT duration groups (&lt; or ≥ 6 months).</div></div><div><h3>Results</h3><div>The analysis included 707 patients with 776 aneurysms. The P2Y12 inhibitor of choice was mainly clopidogrel in 68.7 %, ticagrelor in 15.8 % and prasugrel in 12.2 %. Median DAPT duration was 177 days (IQR 93–227). Younger patients and those with mRS ≤ 2 significantly received longer DAPT. Global ischemic stroke rate was 3.2 % (2.5 % before and 0.7 % after DAPT discontinuation) whereas major bleeding risk was 3.5 % (3.5 % before and 0 % after DAPT discontinuation). Post-discharge ischemic stroke and major bleeding rates were 1.8 % and 1.4 % respectively. Cumulative rates of both thromboembolic complications and ischemic strokes were higher in the &lt; 6 months group (7.5 %) vs &lt; 6 months group (4.6 %) without reaching statistical significance.</div></div><div><h3>Conclusion</h3><div>In this large real-world retrospective analysis, most major adverse events were reported within 30 days post-FDS procedure. Complications rates after discharge and after DAPT discontinuation were very low and similar between DAPT duration groups. These data provide a foundation for designing future prospective studies to evaluate optimal DAPT protocols—both in terms of drug type and duration—which could potentially inform future clinical guidelines.</div></div>","PeriodicalId":50115,"journal":{"name":"Journal of Neuroradiology","volume":"52 5","pages":"Article 101372"},"PeriodicalIF":3.0,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144663279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of M2-segment occlusion angiographic shape on recanalization and clinical outcomes in mechanical thrombectomy","authors":"Osama Elshafei ,&nbsp;Jonathan Cortese ,&nbsp;Ali Gaber ,&nbsp;Eman Eltantawy ,&nbsp;Adrian Dan Popica ,&nbsp;Léon Ikka ,&nbsp;Cristian Mihalea ,&nbsp;Vanessa Chalumeau ,&nbsp;Mariana Sarov ,&nbsp;Olivier Chassin ,&nbsp;Christian Denier ,&nbsp;Jildaz Caroff ,&nbsp;Laurent Spelle","doi":"10.1016/j.neurad.2025.101371","DOIUrl":"10.1016/j.neurad.2025.101371","url":null,"abstract":"<div><h3>Background</h3><div>Mechanical thrombectomy (MT) for M2-segment occlusions of the middle cerebral artery can be an effective treatment for acute ischemic stroke but its effectiveness and the choice of the first line strategy remains unanswered questions. The angiographic shape of the occlusion has been suggested to impact the recanalization rates in M1-segment occlusions. We aimed to investigate whether the angiographic shape of the M2-segment impacts the outcomes of MT with stent retriever (SR) or contact aspiration (CA).</div></div><div><h3>Methods</h3><div>From January 2015 to December 2022, consecutive patients admitted to a single high-volume institution for acute ischemic stroke with an M2-segment occlusion treated by MT were included and retrospectively analyzed. Patients were classified into two groups, regular or irregular, according to the angiographic occlusion shape. Patients demographic, procedural, clinical and safety outcomes data were reviewed.</div></div><div><h3>Results</h3><div>A total of 214 MT procedures were included and categorized as regular (39 %) and irregular (61 %) shape occlusion groups. Interrater agreement was high (<em>k</em> = 94 %). There were no significant differences between the two groups as regard demographic, procedural, clinical and safety outcomes except for smoking (33.5 % vs 16.8 %, <em>p</em> = 0.01). Procedural outcomes, recanalization rates and clinical outcomes did not significantly differ between the regular and irregular occlusion groups. In subgroup analysis, for irregular occlusions SR as a first-line strategy was associated with higher rates of excellent recanalization (mTICI 2c - 3) after the first pass compared to CA±SR (44 % vs 27.16 %, <em>p</em> = 0.05), and also better clinical outcomes, with lower 24-hour NIHSS (<em>p</em> &lt; 0.01) and lower 3-month mRS (<em>p</em> = 0.04). In regular occlusions, no significant differences were found in recanalization rates or clinical outcomes when using SR or CA±SR.</div></div><div><h3>Conclusion</h3><div>Choosing SR as the first line strategy for irregular shape M2-segment occlusions is associated with higher rates of recanalization after the first pass and better clinical outcomes. Further prospective studies are needed to confirm our findings.</div></div>","PeriodicalId":50115,"journal":{"name":"Journal of Neuroradiology","volume":"52 5","pages":"Article 101371"},"PeriodicalIF":3.0,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144634381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Would you board a plane if the pilot had never trained on a flight simulator?","authors":"Baptiste Donnard ,&nbsp;Gregoire Boulouis ,&nbsp;Aymeric Rouchaud ,&nbsp;Gaultier Marnat ,&nbsp;Thibault Agripnidis ,&nbsp;Jean-Pierre Pruvo ,&nbsp;Kevin Janot","doi":"10.1016/j.neurad.2025.101370","DOIUrl":"10.1016/j.neurad.2025.101370","url":null,"abstract":"","PeriodicalId":50115,"journal":{"name":"Journal of Neuroradiology","volume":"52 5","pages":"Article 101370"},"PeriodicalIF":3.0,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}