Journal of Neuroradiology最新文献

{"title":"Assessment of large-scale imaging practices in patients with acute brain hemorrhage in French emergency departments","authors":"Rozenn Mainguy ,&nbsp;Amandine Crombe ,&nbsp;Mylène Seux ,&nbsp;Jérôme Bailleux ,&nbsp;Berengère Delorme ,&nbsp;Marco Pasi ,&nbsp;Jean Philippe Cottier ,&nbsp;Grégoire Boulouis ,&nbsp;Guillaume Gorincour","doi":"10.1016/j.neurad.2024.101222","DOIUrl":"10.1016/j.neurad.2024.101222","url":null,"abstract":"<div><h3>Objective</h3><div>Intracerebral hemorrhage (ICH) is a life-threatening condition, where imaging plays a crucial role but remains poorly standardized. Our main objective was to analyze the imaging protocols used during the acute phase of ICH and ascertain the proportion of patients diagnosed with secondary hemorrhage.</div></div><div><h3>Patients and methods</h3><div>A multicenter retrospective observational study was conducted across over 100 French hospitals affiliated with a national tele-imaging network dedicated to emergency imaging. Among patients managed in the “Stroke Alert” pathway for suspected acute stroke from March 2021 to April 2023, those with ICH diagnosed within 24 h of symptoms onset were identified. Their imaging reports were reviewed to identify the imaging modality used and protocols performed and investigate whether a secondary cause was identified.</div></div><div><h3>Results</h3><div>Of the 18,356 patients included in the ”Stroke Alert” pathway, 662 cerebral hemorrhages were identified (3.6 %). Computed tomography (CT) was the most widely used imaging modality in the acute phase (71.8 % of examinations). Vascular imaging was performed in 78 % of patients with cerebral hemorrhage, most often CT angiography or TOF magnetic resonance angiography. A secondary cause was identified in 8.2 % (54/662) of cerebral hemorrhages, including vascular imaging in the vast majority of cases (92.6 %).</div></div><div><h3>Conclusion</h3><div>Optimization and standardization of imaging protocols in the acute phase of ICH is essential to improve the detection of its secondary causes, particularly vascular, requiring urgent treatment. Vascular imaging improves their early detection.</div></div>","PeriodicalId":50115,"journal":{"name":"Journal of Neuroradiology","volume":"51 6","pages":"Article 101222"},"PeriodicalIF":3.0,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142331453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intracranial aneurysm stiffness assessment using 4D Flow MRI","authors":"Satoshi Koizumi ,&nbsp;Taichi Kin ,&nbsp;Tetsuro Sekine ,&nbsp;Satoshi Kiyofuji ,&nbsp;Motoyuki Umekawa ,&nbsp;Nobuhito Saito","doi":"10.1016/j.neurad.2024.101221","DOIUrl":"10.1016/j.neurad.2024.101221","url":null,"abstract":"<div><h3>Background</h3><div>Although arterial stiffness is known as a biomarker for cardiovascular events and stroke, there is limited information in the literature regarding the stiffness of intracranial aneurysms. In this study, we aim to assess the stiffness of intracranial aneurysms using 4D Flow MRI.</div></div><div><h3>Methods</h3><div>A total of 27 aneurysms in 25 patients with internal carotid artery aneurysms were included in this study. Using 4D Flow MRI, we measured the arterial pulse wave form during a cardiac cycle at planes proximal and distal to the target aneurysm. The damping of these waveforms through the aneurysm was defined as the aneurysm damping index (ADI) and compared to the contralateral side. We also investigated the clinical factors related to the ADI.</div></div><div><h3>Results</h3><div>ADI assessment was successful in all cases. The average ADI was 1.18±0.28, which was significantly larger than 1.0 (<em>P</em> = 0.0027 [<em>t</em>-test]). The ADI on the aneurysm side was larger than on the contralateral side (1.19±0.30 vs 1.05±0.17, <em>P</em> = 0.029 [<em>t</em>-test]). On multivariate analysis, the use of beta-blockers (β=0.46, <em>P</em> = 0.015) and smoking history (β=-0.22, <em>P</em> = 0.024) showed a significant correlation with ADI.</div></div><div><h3>Conclusion</h3><div>We have proposed a novel method to observe arterial pulse wave dumping through intracranial aneurysm using 4D Flow MRI. The damping can be quantitatively observed, and the ADI has correlations with clinical factors such as antihypertensive drugs and smoking. Further studies should focus more on evaluating aneurysm stiffness and its clinical applications.</div></div>","PeriodicalId":50115,"journal":{"name":"Journal of Neuroradiology","volume":"51 6","pages":"Article 101221"},"PeriodicalIF":3.0,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0150986124001482/pdfft?md5=e9a97069eda827fd9dea8fda8b606792&pid=1-s2.0-S0150986124001482-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142299817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PET-MRI neuroimaging of neurovascular uncoupling related to BBB dysfunction: beyond mild traumatic injury","authors":"Eric Guedj,&nbsp;Tatiana Horowitz,&nbsp;Brieg Dissaux,&nbsp;Douraied Ben Salem","doi":"10.1016/j.neurad.2024.101219","DOIUrl":"10.1016/j.neurad.2024.101219","url":null,"abstract":"","PeriodicalId":50115,"journal":{"name":"Journal of Neuroradiology","volume":"51 5","pages":"Article 101219"},"PeriodicalIF":3.0,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142087461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of baseline blood pressure and outcomes in etiology subtypes of large vessel occlusion stroke: Data from ANGEL-ACT registry","authors":"Haifeng Xu ,&nbsp;Dapeng Sun ,&nbsp;Ligang Song ,&nbsp;Dapeng Mo ,&nbsp;Ning Ma ,&nbsp;Anxin Wang ,&nbsp;Feng Gao ,&nbsp;Xuelei Zhang ,&nbsp;Baixue Jia ,&nbsp;Zhongrong Miao ,&nbsp;ANGEL-ACT study group","doi":"10.1016/j.neurad.2024.101213","DOIUrl":"10.1016/j.neurad.2024.101213","url":null,"abstract":"<div><h3>Background</h3><p>Blood pressure (BP) management at the initial stage of stroke caused by large-vessel occlusion (LVO) remains challenging. We assessed the association between baseline BP and clinical and safety outcomes of endovascular treatment (EVT) in different stroke etiologies.</p></div><div><h3>Methods</h3><p>Patients with acute ischemic stroke and anterior circulation LVO were screened from a prospective, multicenter registry of EVT from November 2017 to March 2019. The primary outcome was poor 90-day outcome (modified Rankin Scale score 3–6). The safety outcome was 24 h post-procedure parenchymal hematoma (PH). The Trial of Org 101072 in Acute Stroke Treatment criteria were used for etiologic stroke classification. Restricted cubic spline and binary logistic regression analysis were performed to examine the association between study outcomes and natural log-transformed BP.</p></div><div><h3>Results</h3><p>In subgroup analyses, a U-shaped correlation existed between baseline mean arterial pressure (MAP) and poor outcome in large-artery atherosclerosis stroke only. Higher MAP was an independent risk factor compared with a central reference value (≥ 133 mm Hg vs 96–115 mm Hg; adjusted OR [aOR], 2.50; 95 % CI, 1.09 to 5.71, <em>P</em> = 0.030). Whereas elevated MAP was associated with PH (aOR, 1.58; 95 % CI 1.04 to 2.39, <em>P</em> = 0.030 for a ln10-unit increase in natural log-transformed MAP) in the range &lt;110 mm Hg exclusively for cardioembolic stroke.</p></div><div><h3>Conclusion</h3><p>Whether it is cause or epiphenomenon, baseline BP was associated with 90-day outcome in large-artery atherosclerosis stroke, whereas in cardioembolic stroke baseline BP was correlated with post-procedure PH within a certain range. Identifying these features based on etiological subtypes may offer a reference for BP management in acute LVO stroke.</p></div>","PeriodicalId":50115,"journal":{"name":"Journal of Neuroradiology","volume":"51 5","pages":"Article 101213"},"PeriodicalIF":3.0,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141914464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parallel placement of Woven EndoBridge (WEB) device for the treatment of wide-necked lobulated aneurysms at the basilar tip","authors":"Haoyu Zhu ,&nbsp;Yupeng Zhang ,&nbsp;Shikai Liang ,&nbsp;Chuhan Jiang","doi":"10.1016/j.neurad.2024.101212","DOIUrl":"10.1016/j.neurad.2024.101212","url":null,"abstract":"","PeriodicalId":50115,"journal":{"name":"Journal of Neuroradiology","volume":"51 5","pages":"Article 101212"},"PeriodicalIF":3.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141538817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Simultaneous arterial spin labeling functional MRI and fluorodeoxyglucose PET in mild chronic traumatic brain injury","authors":"Justin Heholt ,&nbsp;Riya Patel ,&nbsp;Faezeh Vedaei ,&nbsp;George Zabrecky ,&nbsp;Nancy Wintering ,&nbsp;Daniel A. Monti ,&nbsp;Ze Wang ,&nbsp;Andrew B. Newberg ,&nbsp;Feroze B. Mohamed","doi":"10.1016/j.neurad.2024.101211","DOIUrl":"10.1016/j.neurad.2024.101211","url":null,"abstract":"<div><h3>Background and purpose</h3><p>To determine the effect of mild chronic traumatic brain injury (cTBI) on cerebral blood flow and metabolism.</p></div><div><h3>Methods</h3><p>62 cTBI and 40 healthy controls (HCs) with no prior history of cTBI underwent both pulsed arterial spin labeling functional magnetic resonance imaging (PASL-fMRI) and fluorodeoxyglucose positron emission tomography (FDG-PET) scanning via a Siemens mMR (simultaneous PET/MRI) scanner. 30 participants also took part in a series of neuropsychological clinical measures (NCMs). Images were processed using statistical parametric mapping software relevant to each modality to generate relative cerebral blood flow (rCBF) and glucose metabolic standardized uptake value ratio (gSUVR) grey matter maps. A voxel-wise two-sample <em>T</em>-test and two-tailed gaussian random field correction for multiple comparisons was performed.</p></div><div><h3>Results</h3><p>cTBI patients showed a significant increase in rCBF and gSUVR in the right thalamus as well as a decrease in bilateral occipital lobes and calcarine sulci. An inverse relationship between rCBF and gSUVR was found in the left frontal lobe, the left precuneus and regions in the right temporal lobe. Within those regions rCBF values correlated with 9 distinct NCMs and gSUVR with 3.</p></div><div><h3>Conclusion</h3><p>Simultaneous PASL-fMRI and FDG-PET can identify functional changes in a mild cTBI population. Within this population FDG-PET identified more regions of functional disturbance than ASL fMRI and NCMs are shown to correlate with rCBF and glucose metabolism (gSUVR) in various brain regions. As a result, both imaging modalities contribute to understanding the underlying pathophysiology and clinical course of mild chronic traumatic brain injury.</p></div>","PeriodicalId":50115,"journal":{"name":"Journal of Neuroradiology","volume":"51 5","pages":"Article 101211"},"PeriodicalIF":3.0,"publicationDate":"2024-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141441005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fetal and postnatal neuroimaging of SUZ12-related overgrowth: Imagawa-matsumoto syndrome","authors":"Onur Simsek,&nbsp;Arastoo Vossough","doi":"10.1016/j.neurad.2024.101210","DOIUrl":"https://doi.org/10.1016/j.neurad.2024.101210","url":null,"abstract":"","PeriodicalId":50115,"journal":{"name":"Journal of Neuroradiology","volume":"51 5","pages":"Article 101210"},"PeriodicalIF":3.5,"publicationDate":"2024-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141291693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endovascular approach to posterior spinal cord AV shunts via the anterior spinal artery","authors":"Silvia Pizzuto ,&nbsp;Jonathan Cortese ,&nbsp;Alessandro Sgreccia ,&nbsp;Federico Di Maria ,&nbsp;Arturo Consoli ,&nbsp;Georges Rodesch","doi":"10.1016/j.neurad.2024.101207","DOIUrl":"10.1016/j.neurad.2024.101207","url":null,"abstract":"<div><p>Intradural spinal cord arteriovenous shunts are challenging vascular lesions with poor prognosis if left untreated. Therapeutic options include endovascular treatment, microsurgery or a combined approach. Surgical approaches are more complex if the lesions are located anteriorly and supplied by the anterior spinal artery (ASA). ASA can also vascularize shunts located on the posterior surface of the spinal cord either by transmedullary arteries, pial circumferential arteries or, if affecting the lower portions of the cord, by the anastomotic channels of the basket. Each of these vessels can be used for endovascular navigation to reach the shunts with good results if appropriate anatomical rules are followed. We describe here some technical considerations based on the anatomical analysis for the embolization of posterior spinal cord arteriovenous shunts vascularized by the anterior spinal artery.</p></div>","PeriodicalId":50115,"journal":{"name":"Journal of Neuroradiology","volume":"51 5","pages":"Article 101207"},"PeriodicalIF":3.5,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141263140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abnormalities in spontaneous brain activity and functional connectivity are associated with cognitive impairments in children with type 1 diabetes mellitus","authors":"Jia-Wen Song ,&nbsp;Xiao-Yan Huang ,&nbsp;Mei Huang ,&nbsp;Shi-Han Cui ,&nbsp;Yong-Jin Zhou ,&nbsp;Xiao-Zheng Liu ,&nbsp;Zhi-Han Yan ,&nbsp;Xin-Jian Ye ,&nbsp;Kun Liu","doi":"10.1016/j.neurad.2024.101209","DOIUrl":"10.1016/j.neurad.2024.101209","url":null,"abstract":"<div><h3>Background</h3><p>It remains unclear whether alterations in brain function occur in the early stage of pediatric type 1 diabetes mellitus(T1DM). We aimed to examine changes in spontaneous brain activity and functional connectivity (FC) in children with T1DM using resting-state functional magnetic resonance imaging (rs-fMRI), and to pinpoint potential links between neural changes and cognitive performance.</p></div><div><h3>Methods</h3><p>In this study, 22 T1DM children and 21 age-, sex-matched healthy controls underwent rs-fMRI. The amplitude of low frequency fluctuations (ALFF) and seed-based FC analysis were performed to examine changes in intrinsic brain activity and functional networks in T1DM children. Partial correlation analyses were utilized to explore the correlations between ALFF values and clinical parameters.</p></div><div><h3>Results</h3><p>The ALFF values were significantly lower in the lingual gyrus (LG) and higher in the left medial superior frontal gyrus (MSFG) in T1DM children compared to controls. Subsequent FC analysis indicated that the LG had decreased FC with bilateral inferior occipital gyrus, and the left MSFG had decreased FC with right precentral gyrus, right inferior parietal gyrus and right postcentral gyrus in children with T1DM. The ALFF values of LG were positively correlated with full-scale intelligence quotient and age at disease onset in T1DM children, while the ALFF values of left MSFG were positively correlated with working memory scores.</p></div><div><h3>Conclusion</h3><p>Our findings revealed abnormal spontaneous activity and FC in brain regions related to visual, memory, default mode network, and sensorimotor network in the early stage of T1DM children, which may aid in further understanding the mechanisms underlying T1DM-associated cognitive dysfunction.</p></div>","PeriodicalId":50115,"journal":{"name":"Journal of Neuroradiology","volume":"51 5","pages":"Article 101209"},"PeriodicalIF":3.5,"publicationDate":"2024-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141184865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pediatric cervical spine clearance after blunt trauma and negative CT: What is the role of MRI?","authors":"Nazanin Azizi,&nbsp;Jimmy L. Huynh,&nbsp;Osama Raslan,&nbsp;Matthew Bobinski,&nbsp;Lotfi Hacein-Bey,&nbsp;Arzu Ozturk","doi":"10.1016/j.neurad.2024.101206","DOIUrl":"10.1016/j.neurad.2024.101206","url":null,"abstract":"<div><h3>Background and purpose</h3><p>The cervical spine in children has marked anatomical and biomechanical differences compared to adults, leading to significantly different patterns and incidence of spinal injury, and consequently to different X-ray and computed tomography (CT) imaging recommendations. Magnetic resonance imaging (MRI) has been validated to clear cervical spine trauma in adults, but not in pediatric patients. We hypothesized that MRI findings have a low probability to change management in children with spine trauma and negative CT findings.</p></div><div><h3>Materials and methods</h3><p>We reviewed records for admitted pediatric patients due to blunt trauma from January 2011 to May 2021, and identified 212 patients who underwent MRI within 3 days of a negative CT. Two neuroradiologists independently reviewed all CT and MRI images for the following categories: fracture, subluxation, spinal canal compromise, ligamentous injury, spinal canal hemorrhage, cord contusion and soft tissue hemorrhage. We identified follow-up MRI examinations as negative or positive for the above categories, and calculated the prevalence of each category as a percentage of cases with negative CT. We also evaluated whether negative and positive MRI groups differed significantly with respect to age and sex of the patients.</p></div><div><h3>Results and conclusions</h3><p>In our study of 212 children with cervical spine trauma and a negative CT, most follow-up MRI scans were found to be negative (79.9 %). Positive MRI findings consisted mainly of ligamentous sprain without disruption (15.1 %). Ligamentous disruption and epidural or soft tissue hemorrhage were found in 4.5 %, and focal cord contusion in 0.5 %. There was no statically significant difference between negative and positive MRI groups with respect to age (<em>P</em> = 0.45) and sex (<em>P</em> = 0.52).</p></div><div><h3>Conclusion</h3><p>In our patient group with a negative CT, MRI did not significantly impact management nor contribute to cervical spine clearance in children.</p></div>","PeriodicalId":50115,"journal":{"name":"Journal of Neuroradiology","volume":"51 5","pages":"Article 101206"},"PeriodicalIF":3.5,"publicationDate":"2024-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141159032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}