Innovations in pharmacy最新文献

{"title":"Effects of Pharmacist Chart Review and Pharmacist Interventions on Diabetes GAP Scores in the Rural Ambulatory Care Setting.","authors":"Austin Steichen, Mark Dewey, Daniel Friesner, DeeAnna Hanson, Sydney Kleven","doi":"10.24926/iip.v16i2.6541","DOIUrl":"10.24926/iip.v16i2.6541","url":null,"abstract":"<p><p><b>Background:</b> The Minnesota Community Measurement assesses health system performance for diabetes care based on five measures: blood glucose (A1c), blood pressure (BP), cholesterol (LDL), tobacco use, and aspirin use, aggregated and known as a \"GAP score.\" Rural areas are negatively impacted by inadequate diabetes care. The positive impact of direct pharmacist patient care on diabetes management is well established, but research on indirect care is lacking. <b>Objective:</b> To assess the impact of pharmacist chart review on GAP scores in a rural primary care clinic. <b>Methods:</b> This was an evidence-based practice project conducted in a rural primary care clinic. Pre- and post-intervention GAP data were collected between January 1, 2023, and February 27, 2024. For each patient, pharmacists reviewed patient medical records for GAP score-related interventions. Reviews were completed at least one day prior to the patient's primary care appointment and sent to the appropriate providers via a secure messaging system. The primary study outcome was the frequency of patients experiencing a reduction in their GAP scores. Secondary outcomes included (1) the frequency of patients meeting the A1c, BP, LDL, tobacco use, and aspirin use GAP goals after one year, and (2) the frequency of patients transitioning from not meeting to meeting each of these GAP goals after one year. The primary and secondary outcomes were compared between the pharmacist and no-pharmacist intervention groups using Chi-square statistics. <b>Results:</b> Patients in the pharmacist intervention group were more likely to experience a reduction in GAP score (p<0.001), and met the A1c and tobacco usage GAP goal more often. Meeting the tobacco use GAP goal, however, was related more to the greater number of patients at goal in the intervention group at baseline. The treatment group was more likely to transition from not meeting to meeting the A1c, blood pressure, and aspirin GAP goals after one year. No significant changes were seen for the LDL GAP goal. <b>Conclusions:</b> Prospective pharmacist chart review may improve diabetes care in rural areas.</p>","PeriodicalId":501014,"journal":{"name":"Innovations in pharmacy","volume":"16 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13233170/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148201963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmacist-Driven Pediatric Vaccine Recommendation and Implementation Service.","authors":"Jacob Sutej, Amy Heiberger, Amanda Hurst","doi":"10.24926/iip.v16i2.6554","DOIUrl":"10.24926/iip.v16i2.6554","url":null,"abstract":"<p><p><b>Background:</b> The Advisory Committee on Immunization Practices recommends improving efforts to vaccinate hospitalized children; however, immunizations are oftentimes only administered in primary care settings. We piloted a pharmacist-driven vaccine recommendation service to increase immunization of hospitalized pediatric patients. <b>Methods:</b> In this prospective cohort study, a pharmacist reviewed the vaccine histories of all immunocompetent patients ages two months to six years hospitalized Monday through Friday in the month of February 2024. If catch-up vaccines were needed, the pharmacist facilitated ordering the immunization(s) to be administered prior to discharge. Intervention data was reported as the number of patients reviewed, percentage of patients who received one or more childhood vaccine(s) in the hospital, and the amount of pharmacist time spent. <b>Results:</b> A total of 130 patients were included, of which 87 (67%) were determined to be up-to-date on immunizations. Among 43 patients eligible to receive a vaccine, 15 patients (35%) received at least one immunization prior to discharge, and a total of 42 vaccines were administered. The median pharmacist time spent per patient obtaining vaccination history and discussing vaccination with the family was 11 minutes and two minutes, respectively. <b>Conclusions:</b> The results of this study confirm that under-vaccination in hospitalized pediatric patients is common, with over 30% of patients missing one or more vaccines. In this study, pharmacist intervention resulted in successful administration of 42 immunizations prior to discharge. Including pharmacists in efforts to improve vaccination of hospitalized children could be considered to decrease the burden of review on inpatient providers and to close the gap on missed immunizations.</p>","PeriodicalId":501014,"journal":{"name":"Innovations in pharmacy","volume":"16 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13233171/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148201951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Navigating mental health conversations: Student pharmacists complete Mental Health First Aid Training and apply it through experiential learning in a community pharmacy depression screening program.","authors":"Shannon Habba, David Frond, Kyle Burghardt, Brittany Stewart","doi":"10.24926/iip.v16i2.6452","DOIUrl":"10.24926/iip.v16i2.6452","url":null,"abstract":"<p><p><b>Background:</b> Community pharmacies offer a unique and accessible opportunity to close the existing mental health care gap. Many pharmacists and student pharmacists, however, lack the confidence to effectively engage in conversations regarding mental health. The objective of this study was to assess student pharmacist confidence and knowledge in navigating mental health conversations after Mental Health First Aid (MHFA) training alone versus MHFA training paired with experiential learning opportunities through community pharmacy-based depression screening events. <b>Methods:</b> Student pharmacists in their second through fourth years were recruited to participate in this study. All participants completed a pre-survey to assess baseline knowledge and confidence, underwent MHFA training, and were given the option to participate in community-based depression screenings. A post-survey was then given to assess changes in knowledge and confidence. Survey responses were compared between students who attended depression screening sessions and those who did not. <b>Results:</b> Twenty students completed the study. Of these 20 students, 13 participated in the depression screenings. Students who completed both MHFA training and depression screening events showed greater improvement in mental health knowledge (P=0.03) and confidence (P=0.03) compared to those who completed MHFA training alone. <b>Conclusion:</b> When paired with experiential learning opportunities, MHFA training significantly improves student pharmacists' knowledge and confidence in navigating mental health conversations.</p>","PeriodicalId":501014,"journal":{"name":"Innovations in pharmacy","volume":"16 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13233172/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148201958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between leadership strengths and imposter phenomenon in pharmacy professionals and students.","authors":"Jaclyn D Cole, Anthony DeClue, Jordan Marie Ballou, Kristy Brittain, Melissa J Ruble, Caroline Sasser, Caroline L Ko, Melissa Noble, Brandon T Jennings","doi":"10.24926/iip.v16i2.6441","DOIUrl":"10.24926/iip.v16i2.6441","url":null,"abstract":"<p><p><b>Objective</b>: To identify trends between leadership strengths and the prevalence of imposter phenomenon (IP), with a secondary focus on growth mindset. <b>Methods:</b> An anonymous electronic survey invitation was shared through email and social media accounts, targeting pharmacists and pharmacy students who had completed the GiANT Worldwide 5 Voices Assessment utilized by the Phi Lambda Sigma Leadership Society for leadership development. Survey content included leadership voice order, Clance Imposter Phenomenon (CIP) scale, and Implicit Theories of Intelligence Scale (ITIS). Responses were analyzed through both descriptive and inferential statistics. <b>Results:</b> Twenty-five respondents were included in the final analysis: P3 students (n=4), P4 students (n=6), PGY-1 residents (n=4), PGY-2 residents (n=1), practicing pharmacists (n=4), pharmacy faculty members (n=3), and did not disclose (n=3). Primary voices included 9 Nurturers (36%), 7 Pioneers (28%), 3 Connectors (12%), 3 Creatives (12%), and 3 Guardians (12%). Pioneers (CIP mean=67.43) and Nurturers (CIP mean=66) reported high IP, while Connectors had the least IP prevalence at a moderate level (CIP mean=50.33). Growth mindset was more prevalent in Pioneers and Connectors, while Nurturers more commonly reported a fixed mindset. <b>Conclusion:</b> These findings suggest that the prevalence of IP cannot be assumed based on the volume or perspective (future vs. present orientation) of individual leadership strengths. The prevalence of IP did not appear to correlate with reported growth mindset.</p>","PeriodicalId":501014,"journal":{"name":"Innovations in pharmacy","volume":"16 2","pages":"6441"},"PeriodicalIF":0.0,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13233174/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148201938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of a Pharmacist-Led Telehealth Intervention on Medication Adherence for Patients with Substance Use Disorder in a Rural Community Pharmacy.","authors":"Janice T Nguyen, Scott M Sexton, Jonni Williams","doi":"10.24926/iip.v16i2.6666","DOIUrl":"10.24926/iip.v16i2.6666","url":null,"abstract":"<p><p><b>Background</b>:Substance use disorder has significantly affected the lives of individuals throughout the United States. Pharmacists are well-positioned to assist with medication adherence and other medication-related problems related to substance use disorder treatment. With virtual care becoming readily available, telehealth helps patients to achieve the care they need and helps to overcome the barriers to accessing in-person patient appointments. <b>Objective</b>:To assess the impact of a pharmacist-led telehealth intervention on medication adherence for patients with substance use disorder currently enrolled in a treatment program. The secondary objectives were to evaluate patient relapse rates and determine overall patient satisfaction with pharmacist-driven telehealth services. <b>Methods</b>: The pharmacist-led telehealth program held up to 5 monthly appointments with patients who were seeing a physician for treatment of substance use disorder. Following these appointments, data related to medication adherence, relapse rates, social determinants of health, and patient satisfaction were collected. <b>Results</b>: Six patients enrolled in the substance use disorder telehealth service and completed at least one appointment. Five of these patients completed the full program. A majority of these patients were being treated for opioid use disorder and were taking suboxone. Five of the six patients met adherence goals of 80-100%, with all patients improving adherence from their first visit to their last visit. <b>Conclusion</b>: The implementation of a pharmacist-led intervention of support services for patients with substance use disorder improved medication adherence. The pharmacists were able to address additional issues such as side effects, social determinants of health, and medication cost at these telehealth appointments.</p>","PeriodicalId":501014,"journal":{"name":"Innovations in pharmacy","volume":"16 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13233179/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148201882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of Drug-Device Combination Products and Generic Substitution in the United States.","authors":"Ila Srivastava, YoonJung Lee, Katharine B Feibus, Elizabeth R Bielski, Lolita Sterrett, Danielle Harris, Markham C Luke","doi":"10.24926/iip.v16i2.6461","DOIUrl":"10.24926/iip.v16i2.6461","url":null,"abstract":"<p><p>Generic drug products approved and marketed in the United States include a variety of drug classes and dosage forms along with drug-device combination products (DDCPs). Development of DDCPs can pose scientific, regulatory, and legal challenges, and the Food and Drug Administration (FDA) has prioritized efforts to work with industry to improve scientific methodologies and application quality in an effort to provide quicker access to high-quality generic DDCPs. Once these products become available in the market, the roles of pharmacists and other healthcare providers (HCPs) become crucial. When prescribing, HCPs should provide risk/benefit counseling and, to prevent medication errors, teach patients about the proper use of these products. This review provides a comprehensive overview of the regulatory and developmental processes of generic DDCPs to help pharmacists and other healthcare professionals engage more effectively with patients.</p>","PeriodicalId":501014,"journal":{"name":"Innovations in pharmacy","volume":"16 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13233167/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148201786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Angiotensin-Neprilysin Inhibitor Therapy: A Retrospective Chart Study.","authors":"Roda Plakogiannis, Abraham Stefanidis, Nubriel Hernandez, Etty Vider","doi":"10.24926/iip.v16i1.6428","DOIUrl":"10.24926/iip.v16i1.6428","url":null,"abstract":"<p><p><i>Background:</i> Guideline-directed medical therapy in patients with systolic heart failure (HF) has demonstrated improvement in morbidity and mortality rates. The FDA approved sacubitril/valsartan in 2015 to reduce the risk of cardiovascular death and hospitalization for HF. <i>Objective:</i> The purpose of this study was to evaluate the change in loop diuretic dose and the clinical outcomes of angiotensin receptor-neprilysin inhibitor (ARNI) therapy within a 90-day follow-up period. <i>Methods:</i> A retrospective chart review of 110 HF patients on concomitant ARNI and loop diuretic therapy at New York University Langone Health was conducted. The primary endpoint was a change in loop diuretic dose. Six secondary endpoints, including dose conversion from ACEi or ARB to ARNI therapy, were assessed. <i>Results:</i> Of the 110 HF patients, 72 did not receive diuretic dose adjustments, yet 40 (55.56%) experienced laboratory-dependent dehydration. Fifty-six percent of patients experienced an improvement in systolic blood pressure, and 52 percent experienced a decrease in diastolic blood pressure. Sixty percent of patients experienced an improvement in EF, with a median increase of 10.00% over a 90-day follow-up. A significant negative correlation between patients' age and absolute change in EF was identified (r= -0.28; p < 0.05), indicating that the increase in EF was stronger for younger patients. Eighteen hospitalizations occurred within a 90-day follow-up, with only 4 patients being admitted for heart failure exacerbation. <i>Conclusion and Relevance:</i> This study examines the real-world effects of ARNI therapy in patients with systolic heart failure. Optimization of HF medications, including ARNI therapy, remains an important factor for achieving the maximum benefits in heart failure management. ARNI therapy requires careful monitoring to ensure effective diuresis in symptomatic heart failure patients while avoiding adverse events. Future studies should address diuretic dose adjustment in conjunction with the administration of ARNI and sodium-glucose cotransporter-2 inhibitors.</p>","PeriodicalId":501014,"journal":{"name":"Innovations in pharmacy","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12509722/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145282387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nigeria's Pharmaceutical Industry: Addressing Over-Reliance on Importation and Proposing Sustainable Solutions.","authors":"David Ololade Atanda, Joshua Ayodeji Abolade, Rhoda Oluwadamilola Olatuyi, Esther Oyinlola Olatunbosun","doi":"10.24926/iip.v16i1.6502","DOIUrl":"10.24926/iip.v16i1.6502","url":null,"abstract":"<p><p>In Africa, Nigeria can be regarded as the most populous country with a population size of 227 million people and also a lower-middle-income country. As at 2014, according to a report by WHO, 25% of the pharmaceutical products needed by Nigerians were delivered locally, while the remaining 75% are imported from nations such as India, UK and China, this performance indices indicate poor performance. Due to the heavy reliance on importation faced by the Nigeria's pharmaceutical industry, access to medicines that are essential has been limited and local production capacity has weakened. With the growing interest in plant-based therapies, dosage standardisation for many of these herbal products due to insufficient funding for extensive research into herbal medicine and insufficient clinical trials has made it difficult to assess the effectiveness of herbal treatment systematically and validate scientifically the traditional remedies. Limited facilities for in-vivo and in-vitro studies further limits knowledge advancement in pharmaceutical sciences. The effects of these situations have resulted into drug shortages, prolific substandard medicines and vulnerability to supply chain disruptions. Addressing these challenges requires a multifaceted approach involving policy reform, and the establishment of well-equipped pharmaceutical research and production facilities. Countries such as India and the United States have implemented initiatives backed up by the government which has enabled local companies to manufacture APIs, enhance self-sufficiency in healthcare and research capabilities. Nigeria can adopt similar strategies to reduce dependency on importation and promote innovation in the pharmaceutical sector.</p>","PeriodicalId":501014,"journal":{"name":"Innovations in pharmacy","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12509718/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145282503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Patient Assistance Program Committee at the Jackson Free Clinic: Discussing the Need, Design, and Implementation.","authors":"Gregory R Vance, Johnny Yang, Nickhil Rugnath, Leonna Conley, Victoria Green, Harshin Sanjanwala, Chin B Yen, Amanda Pham, John D Salvemini, James Pitcock","doi":"10.24926/iip.v16i1.6496","DOIUrl":"10.24926/iip.v16i1.6496","url":null,"abstract":"<p><p>Many populations face the barriers of high medication costs due to limited resources, especially those served by student-run free clinics (SRFCs). As part of the solution, patient assistance programs (PAPs) managed through pharmaceutical companies provide free medications to patients who are unable to afford them. Various PAP-related interventions have been proven to improve efficiency and patient care in SRFCs. The Jackson Free Clinic (JFC) serves some of the most vulnerable populations in Mississippi, which as a state has performed poorly nationally in a variety of healthcare metrics. Proximity to such a population and access to service from training health professionals provides a unique opportunity to create change by implementation of student-driven PAP services. The newly established PAP committee undertakes the tasks necessary to enroll, track, and dispense individual patients' medications received through enrollment in an assistance program specific to the needed medication. The hope of the PAP committee is to reduce the responsibility of medical and pharmacy teams, increase enrollment likelihood, improve medication adherence, decrease patient wait time, and improve patient care. The development of the PAP committee has shown the value of implementing an organized PAP formulary, a consistent organizational structure, and an all-inclusive written hand-guide, which has created an improved training environment for committee members. Other results reported by regional SRFCs have suggested the clinical and cost benefits of implementing PAPs, particularly a committee. The novel method employed at JFC requires additional research and development toward the larger effort of improving patient care, which we plan to investigate with future endeavors.</p>","PeriodicalId":501014,"journal":{"name":"Innovations in pharmacy","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12509720/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145282505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding Space Pharmacy Education for Pharmacists with the Teeter-Totter Model: If-Then Logic Model and Socio-Ecological Framework for Space Pharmacy Council.","authors":"Muhammad Ahmer Raza","doi":"10.24926/iip.v16i1.6598","DOIUrl":"10.24926/iip.v16i1.6598","url":null,"abstract":"<p><p>Letter to the Editor.</p>","PeriodicalId":501014,"journal":{"name":"Innovations in pharmacy","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12509715/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145282540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}